Just for clarification: the BPA diet study on the mouse model, it doesn’t necessarily conclude if low methylation/high methylation is good/bad, right? The main conclusion is that, we see BPA diet can affect the methylation in mouse gene expression of the yellow fur coat gene - which means is just one example of how gene expression can be affected by something like BPA. Would that be correct ?
You are correct: this experiment tells us only that the diet and environment are able to influence genome methylation. The inference would be, the abundance of manmade chemicals and preservatives in our modern world might be having unpredicted (and unpredictable) effects on our genes and thus our health and development...and that of future generations.
Really good ,lucidly explained 👏
Very-well explained. Thank you so much!
amazing🐁
Just for clarification: the BPA diet study on the mouse model, it doesn’t necessarily conclude if low methylation/high methylation is good/bad, right? The main conclusion is that, we see BPA diet can affect the methylation in mouse gene expression of the yellow fur coat gene - which means is just one example of how gene expression can be affected by something like BPA. Would that be correct ?
You are correct: this experiment tells us only that the diet and environment are able to influence genome methylation.
The inference would be, the abundance of manmade chemicals and preservatives in our modern world might be having unpredicted (and unpredictable) effects on our genes and thus our health and development...and that of future generations.
Why does the methylation diet not impact the fur color of the mother but is passed on to the offspring?
I think it's because it is happening during the development of the mouse, not necessarily after the mouse has developed and grown.