Analgesic Pathway | Endogenous Opioid System

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  • เผยแพร่เมื่อ 21 ก.ย. 2024

ความคิดเห็น • 84

  • @nimrakhan6143
    @nimrakhan6143 3 ปีที่แล้ว +25

    Dr Mike you so simply and clearly explain in 10 mins what my teachers cannot explain even after hours of lectures.

  • @JL-dx1ov
    @JL-dx1ov 3 ปีที่แล้ว +4

    Roger Federer makes tennis look easy, DR MIKE makes neuroscience look easy.
    Quality of the great. Thank you, namaste.

  • @wethenatureenthusiastssa1736
    @wethenatureenthusiastssa1736 3 ปีที่แล้ว +6

    Thank you so much from the bottom of my ♥

  • @colacolette19
    @colacolette19 3 ปีที่แล้ว +11

    excellent video! I've been looking for hours for the right video on ascending and descending pathways, and this is both informative and engaging! Tysm!

  • @howtomedicate
    @howtomedicate 4 ปีที่แล้ว +5

    Well explained video!
    It makes me also think of the fear-pain-cyclus. Where fear for pain, leads to tention which causes more pain. And this pain leads to more fear, and so on.

  • @Lisboacampelo
    @Lisboacampelo 3 ปีที่แล้ว +2

    I'm a brazilian student, and your video really helped me. Thank you,.

  • @gilbertocarrijodocoutofilh840
    @gilbertocarrijodocoutofilh840 3 ปีที่แล้ว +1

    One thing is read and hardly imagine. Other different thing is see, understand and believe. Thanks, you cured my blindness about this Topic.

  • @tarabrown8343
    @tarabrown8343 4 ปีที่แล้ว +9

    Love your style of teaching. I teach using the whiteboard too. So helpful. I also appreciate your explanation of everything. Your videos helped me so much for my uni exams. Thank you!

  • @peterngangahsc9945
    @peterngangahsc9945 3 ปีที่แล้ว +1

    Here in Kenya we say "asante sana" in swahili language, meaning "thank you very much" the video is educative

  • @claregoodwin1694
    @claregoodwin1694 2 ปีที่แล้ว +2

    Thank you, great video, it's helped me to get my head around this topic

  • @menamohamedelshehawi4271
    @menamohamedelshehawi4271 3 ปีที่แล้ว +1

    I don't know if he is a reaaaally good teacher or if its his mcdreamy look but all in all I finallyyy understood this part of neurophysiology
    thank you

  • @53-priyankatodkar44
    @53-priyankatodkar44 3 ปีที่แล้ว +3

    It really gives a clarity about this topic, Thanks 😊

  • @shahada8002
    @shahada8002 3 ปีที่แล้ว +2

    Perfect, thank you so much Doctor

  • @brookeminihan4123
    @brookeminihan4123 3 ปีที่แล้ว +2

    Great explanation!

  • @juanluisfernandez5985
    @juanluisfernandez5985 4 ปีที่แล้ว +4

    Your videos are awesome; because of that and to satisfy my curiosity, can I know a little bit about your professional background? Thanks

  • @haileymarshal8180
    @haileymarshal8180 2 ปีที่แล้ว +1

    thanks

  • @unoriginalpotato4924
    @unoriginalpotato4924 4 ปีที่แล้ว +2

    You are an amazing teacher!

  • @leticiabueno3761
    @leticiabueno3761 2 ปีที่แล้ว +1

    amazing, thank you so much for this video :)

  • @floryriana641
    @floryriana641 ปีที่แล้ว

    bro, i read multiple lecture notes and couldnt understand a thingg. But Dr Mike just explained all of those in just 9 minutessss!!

  • @Aya-sp6xe
    @Aya-sp6xe 4 ปีที่แล้ว +1

    ماشاء الله هايل جدا هكذا تستحق لقب الدكتور

  • @cbbhvjc
    @cbbhvjc 3 ปีที่แล้ว +1

    Amazing circuit so well explained!

  • @MT_Method
    @MT_Method 6 หลายเดือนก่อน

    Beautiful video, just have to say that it’s not mentioned the dorsal ganglia of the dorsal root. Thanks a lot Dr Mike!

  • @nohaali6176
    @nohaali6176 3 ปีที่แล้ว +1

    Thank you, I was quite confused in this part until I watched this video

  • @jessicarivera7059
    @jessicarivera7059 4 ปีที่แล้ว +2

    Wonderful video!!! You're a great educator.

  • @MemeCrew5690
    @MemeCrew5690 4 ปีที่แล้ว +2

    Awesome! Thank you so much! I love your videos!

  • @Thomaseron2
    @Thomaseron2 3 ปีที่แล้ว +1

    Very educational, thank you! Wanted to know a bit more about pain relief since my cat bit me at the vet the other day. Got me thinking, if serotonin and opioids are released for pain relief that could possibly explain why some people with depression cut themselves.

  • @pocachontaspocachontas726
    @pocachontaspocachontas726 3 หลายเดือนก่อน

    Thank you, Dr. 👍

    • @DrMattDrMike
      @DrMattDrMike  3 หลายเดือนก่อน

      You're most welcome!

  • @hibar4852
    @hibar4852 4 ปีที่แล้ว +2

    THIS IS SO GOOD THANK YOU!!

  • @ahmadqurashy110
    @ahmadqurashy110 4 ปีที่แล้ว +2

    Amazing
    Thanks doctor ❤

  • @alexandrashields2600
    @alexandrashields2600 8 หลายเดือนก่อน

    Wonderful, thanks again for an amazing and easy to understand video!

  • @medsurgmaster
    @medsurgmaster 3 ปีที่แล้ว +9

    No matter how much my teachers explain I have become addictive
    Your videos have morphine like properties 😂
    Thank you

  • @user-bb1fy2lu4j
    @user-bb1fy2lu4j ปีที่แล้ว

    Thank you very much doctor , we appreciate your hardwork
    now I finally understand this pathway 😊

  • @jonatanduelund9123
    @jonatanduelund9123 ปีที่แล้ว

    Excellent overview and summation thank you! PS great pacing

  • @WannaCry_Alpha
    @WannaCry_Alpha 3 ปีที่แล้ว

    Nice visualization... It made easier to understand...

  • @booksetmore1219
    @booksetmore1219 3 ปีที่แล้ว +3

    Is the enkephalin synapse the same kind of synapse that is mentioned within the Gate Control theory? :) Great video, such a great visualization and explained well!

  • @violetarlein
    @violetarlein 2 ปีที่แล้ว

    superb. thank you for having made this video

  • @I_love_BTS_2025
    @I_love_BTS_2025 3 ปีที่แล้ว +1

    Thanks a lot for this awesome explanation😍🥰

  • @luckyhans6300
    @luckyhans6300 2 ปีที่แล้ว

    Wow ! u r just amazing

  • @lethargicguy3374
    @lethargicguy3374 ปีที่แล้ว

    Very clear and concise ⭐

  • @pacifiquebusiness
    @pacifiquebusiness 3 หลายเดือนก่อน

    Thank You 🙏

    • @DrMattDrMike
      @DrMattDrMike  3 หลายเดือนก่อน

      You’re welcome 😊

  • @sudeeptalapatra3982
    @sudeeptalapatra3982 2 ปีที่แล้ว +1

    Hats of to you sir....I could not get this concept clearly from book, this video makes it crystal clear but you didn't explain pre and post synaptic inhibition by encaphalinergic interneuron i.e neurotransmitter block and K+ channel block.... add it sir...

  • @gordiking506
    @gordiking506 3 ปีที่แล้ว

    super cool!!

  • @asmaulhossain2320
    @asmaulhossain2320 3 ปีที่แล้ว +1

    Really superb ♥

  • @jasmineothman3492
    @jasmineothman3492 ปีที่แล้ว

    great! 🙏🌿

  • @zakirzak1494
    @zakirzak1494 4 ปีที่แล้ว +1

    Great video .... could you do a video about how they identify the receptors and the various Brian pathways so accurately. I mean micro details not the macro. Thank you 🙏

  • @MyNameisDianaa
    @MyNameisDianaa 4 ปีที่แล้ว +1

    incredible!!

  • @homeopathymedicos3849
    @homeopathymedicos3849 4 ปีที่แล้ว +1

    Thanks sir ,

  • @AK.ALMAHASNEH
    @AK.ALMAHASNEH 3 ปีที่แล้ว

    Thank you so much 🍀🍀♥️

  • @hhhafyoo8510
    @hhhafyoo8510 7 หลายเดือนก่อน

    best of the best

  • @spidwars
    @spidwars 3 ปีที่แล้ว

    Thamk you

  • @asmaabbas1110
    @asmaabbas1110 ปีที่แล้ว

    Perfecto 👏

  • @PhysiologywithChristian
    @PhysiologywithChristian 4 ปีที่แล้ว +1

    Great video!

  • @Tannyyyyyyyyyyy
    @Tannyyyyyyyyyyy 3 ปีที่แล้ว +1

    Thanks sir😇

  • @ploptunez5529
    @ploptunez5529 3 ปีที่แล้ว

    Probably should of watched this before doing my UNI quiz, 🤔 and the answer is Delta 🙌🙌, I answered MU because I had absolutely no idea 🙁

  • @kristilacey7802
    @kristilacey7802 ปีที่แล้ว

    Absolute "🤩rippa" - Thanking you

  • @mscrunchy68
    @mscrunchy68 3 ปีที่แล้ว

    When we are experiencing a lot of pain it's easy to think that our endogenous pain relief isn't doing very much but I had ABGs taken shortly after giving birth and couldn't feel anything more than a slight nudging at my wrist, so something was working.

  • @MsRightio
    @MsRightio ปีที่แล้ว

    Is it a coincidence that enkephalin has a similar sound to encephalitis?

  • @PureLogic777
    @PureLogic777 4 ปีที่แล้ว +5

    Great lecture. Does this activation of the analgesic pathway by pain in one area of the body provide some body-wide analgesia? Or is it more focused than that? I've noticed when I eat pepper the mild burn in my mouth will stop a mild headache. Thanks

    • @cullis8327
      @cullis8327 3 ปีที่แล้ว

      In my experience, getting whipped is like taking a high dose of xanax, except you don't feel foggy, just kinda clear afterwards. And yeah, whole body.
      Obviously hard to OD or get addicted, it's exquisitely painful and thus only really an emergency fix.

    • @spiritlevelstudios
      @spiritlevelstudios 2 ปีที่แล้ว

      @@cullis8327 wtf

    • @cullis8327
      @cullis8327 2 ปีที่แล้ว

      @@spiritlevelstudiosi guess you're new to the world. That's how it works. Injury causes the body to release opioids it produces to counteract the pain. But if methods that just cause pain, without real injury are used, such as e.g. wide belts, you just get the opioids in exchange for brief, intense pain.
      It's pretty funny, because e.g. religious ascetics sometimes whip themselves on a faith basis.
      In essence and in effect, what they're doing is not much different than chewing down on some oxy pills.
      Still, it's impressive, because inflicting serious enough pain on yourself to trigger the opioid release is not easy, at all.

  • @fahatmohamed7613
    @fahatmohamed7613 ปีที่แล้ว

    Just wow

  • @amisoumak
    @amisoumak 3 ปีที่แล้ว

    The cross section of spinal cord is wrong

  • @josephsvennson5694
    @josephsvennson5694 4 ปีที่แล้ว +2

    If my Dr looked like Dr Mike my periaqueductal gray would explode.

  • @hariompandey4788
    @hariompandey4788 10 หลายเดือนก่อน

    Physique🔥

  • @JustinRawley
    @JustinRawley 3 ปีที่แล้ว

    Very nice review; however, you stubbed your toe, then mapped the toe to the lip/face area of the SI.

  • @deekircher21
    @deekircher21 4 ปีที่แล้ว

    May you please do a video on DNA?

  • @minallraj9116
    @minallraj9116 3 ปีที่แล้ว +1

    Cool

  • @osamaalhuthifi1388
    @osamaalhuthifi1388 ปีที่แล้ว

    Wow

  • @aryannaghavi3987
    @aryannaghavi3987 2 ปีที่แล้ว

    triceps 🤲🏼

  • @tonytony792655
    @tonytony792655 ปีที่แล้ว

    cool

  • @raghad5356
    @raghad5356 6 หลายเดือนก่อน

    دكتور انا احبك

  • @islamanwar860
    @islamanwar860 2 ปีที่แล้ว

    ❤️❤️❤️❤️❤️❤️❤️

  • @gurkeetsingh9165
    @gurkeetsingh9165 ปีที่แล้ว

    Biceps 💯

  • @rudyy1295
    @rudyy1295 2 ปีที่แล้ว

    Sir you should know that it really is hard to concentrate while you have all these muscles showin off-

  • @Amal-fq1wn
    @Amal-fq1wn 2 ปีที่แล้ว

    i love u

  • @robertschrum5496
    @robertschrum5496 ปีที่แล้ว

    Plz print in large caps so d audience can read what u r saying. CC is so awful.

  • @TM-ey5py
    @TM-ey5py 3 ปีที่แล้ว

    It looks like you’re wearing a kid’s t-shirt.

  • @salvinorindoge3811
    @salvinorindoge3811 4 ปีที่แล้ว

    thanks