I can't thank you enough! Your videos helped me through nursing school 5 years ago, and are now helping me with my Oncology certification, this is clear concise and to the point!
We need teachers like you so that learning is never boring, Thankyou for such amazing videos with great artwork that keeps me motivated through out the time.
This is incredible! Thank you so much for creating this. I’m struggling through my chemotherapy administration training as a RN, and this really helps get an overview of the modes of action of the major groups. Thanks again!!
I'm already familiar with the categories of chemotherapeutic drugs, but this video does an incredible job of drilling down to the details of the mechanisms of action. Bravo!!
Hey, I am thankful! I cant thank you more. Your vedios really made this difficult topic seem easy. And these drawings provided me a vision to understand concepts and visualize answers during exam. I hope you make a second vedio of this anticancer agents part 2.
Hey, Armando, your way of explanation such difficult concepts is superb. indeed very helpful for meds students easy to remember and full of knowledge material appreciated and regards
In recent years, the discovery of cancer stem cells has revolutionized our understanding of this disease. It has long been known there is incredible heterogeneity in a tumor, and now it seems these dangerous cells that often resemble pluripotent stem cells sit at the top of the hierarchy. It now seems apparent this small subpopulation of cells is crucial to the self proliferation, self renewal, refraction to treatment, and most importantly metastasis that characterize cancer as a disease. Some studies have shown that 1 in 400,000 non-stem cancer cells may undergo EMT and tumorigeneses (metastasis), compared to 1 in 7 of these cancer stem cells. As stem cells, they are incredibly robust cells that are difficult to kill, since their survival is crucial to the survival of our species and are forcing us to rethink our understanding and treatment of cancer. It was shown in one study that this small population of cells are nearly immune to chemotherapeutic treatment and highly resistant to ionizing radiation. As the scientists applied chemotherapeutic treatment to tumors in vivo, the proportion of cancer stem cells that was originally about 2% of the cells in the tumor became over 20%, suggesting that the treatment was killing the "bulk" tumor cells that are incapable of metastasis and selecting for the survival of these far more dangerous cells. They are immunologically privileged, employ drug efflux pumps to remove chemotherapeutic agents, and have constituitively active DNA repair mechanisms (contrary to the believe repair mechanisms fail in all cancer cells) that protect from radiation induced damage. We measure drug efficacy in oncology almost solely upon the principle of tumor remission, or the shrinking of a tumor in size after treatment. Again, evidence is mounting that suggests we are selecting for the survival of these cells and initial remissions represent the death of cancer cells that are not stem cells and therefore largely incapable of metastasis. To all the future physicians, researchers, and oncologists out there reading this, you must be aware of these robust and dangerous cells, and I challenge you to find new ways to specifically target and destroy them.
im learning this in colledge now (pharmacy), you really did well in breaking this down and briefly explaining almost each group, this is really a good video for getting a little into the subject before starting learning it more in depth and its a great video for a brief summary (repetition) of the material you just earned a new sub ! well done mate and thank you for doing this !
Before I ask anything, your videos have helped me a lot with my essay about chemotherapy, so thank you for that! However, one youtube video isn't much of a source and I find it hard to find good scientific sources who go by the basics before getting specific. I see the link in the descriptions, but do you perhaps have a list with papers/chapters you've used?
You just covered a two hour lecture in 14 mins. God bless you
HBB gene 🧬 biological treatment honey 👌🦚🐝😂❤
I can't thank you enough! Your videos helped me through nursing school 5 years ago, and are now helping me with my Oncology certification, this is clear concise and to the point!
You have no idea, how many lives of medical students you are saving😊😢🎉🎉
We need teachers like you so that learning is never boring, Thankyou for such amazing videos with great artwork that keeps me motivated through out the time.
This is incredible! Thank you so much for creating this. I’m struggling through my chemotherapy administration training as a RN, and this really helps get an overview of the modes of action of the major groups. Thanks again!!
Thank you Satanic Matrix Awareness for having the Balls to post this video! Kill Chemo Doctors Song 🔥
th-cam.com/video/MQfWcPiCcc8/w-d-xo.html
Clear to understand.looking forward to more topic about pharmacology .
I'm already familiar with the categories of chemotherapeutic drugs, but this video does an incredible job of drilling down to the details of the mechanisms of action. Bravo!!
awesome video to go through before starting a chapter. simple wording explaining all the relevant details. 14 mins and you are done😊💖
Pharmacy student here… thank you so so so much for the insanely clear explanations
Thank you so much. I’m a new grad nurse and assigned in Oncology, this saved me a lot.
Your diagrams are magical, made understand everything........
Your drawings are magic
Very helpful!! 🙂 Even for the clear and succinct explanation of the cell cycle!! Pay attention people!! 🧐🙏 Great presentation. Thanks!
Thank you for clarifying mechanism of action within short period of time.
Hey, I am thankful! I cant thank you more. Your vedios really made this difficult topic seem easy. And these drawings provided me a vision to understand concepts and visualize answers during exam. I hope you make a second vedio of this anticancer agents part 2.
thankyouu, this 14-minutes video beats the whole 2 hours of my lecturer explanations!!
Hands down the most beautiful drawn diagram ive ever seen wtf
Hey, Armando, your way of explanation such difficult concepts is superb.
indeed very helpful for meds students
easy to remember and full of knowledge material
appreciated and regards
Very clear and doubtfree video on Chemotherapy.
In recent years, the discovery of cancer stem cells has revolutionized our understanding of this disease. It has long been known there is incredible heterogeneity in a tumor, and now it seems these dangerous cells that often resemble pluripotent stem cells sit at the top of the hierarchy. It now seems apparent this small subpopulation of cells is crucial to the self proliferation, self renewal, refraction to treatment, and most importantly metastasis that characterize cancer as a disease. Some studies have shown that 1 in 400,000 non-stem cancer cells may undergo EMT and tumorigeneses (metastasis), compared to 1 in 7 of these cancer stem cells.
As stem cells, they are incredibly robust cells that are difficult to kill, since their survival is crucial to the survival of our species and are forcing us to rethink our understanding and treatment of cancer. It was shown in one study that this small population of cells are nearly immune to chemotherapeutic treatment and highly resistant to ionizing radiation. As the scientists applied chemotherapeutic treatment to tumors in vivo, the proportion of cancer stem cells that was originally about 2% of the cells in the tumor became over 20%, suggesting that the treatment was killing the "bulk" tumor cells that are incapable of metastasis and selecting for the survival of these far more dangerous cells. They are immunologically privileged, employ drug efflux pumps to remove chemotherapeutic agents, and have constituitively active DNA repair mechanisms (contrary to the believe repair mechanisms fail in all cancer cells) that protect from radiation induced damage.
We measure drug efficacy in oncology almost solely upon the principle of tumor remission, or the shrinking of a tumor in size after treatment. Again, evidence is mounting that suggests we are selecting for the survival of these cells and initial remissions represent the death of cancer cells that are not stem cells and therefore largely incapable of metastasis. To all the future physicians, researchers, and oncologists out there reading this, you must be aware of these robust and dangerous cells, and I challenge you to find new ways to specifically target and destroy them.
Thank you! Your illustrations are always great and you speak clearly that's easy to understand!
Always You have a solution for confusions MaShaAllah. Continue your work . Best of luck for future. InShAllah you will get best reward
Thank you, you are an amazing teacher and a brilliant illustrator.
This helped a lot for understanding antineoplastic agents. Thankyou ✨
Im too stupid for this
😂😂
Same
Same
😂😂😂
Especially one hour before exam
One of the best lesions
I have been a subscriber for a long time now,and your work is impressive you are an amazing teacher!!Congratulations for 1M+ subscribers
im learning this in colledge now (pharmacy), you really did well in breaking this down and briefly explaining almost each group, this is really a good video for getting a little into the subject before starting learning it more in depth and its a great video for a brief summary (repetition) of the material
you just earned a new sub ! well done mate and thank you for doing this !
I have to say: Thank you very much.
The best anticancer medicine video!
The explanation is very clear and nice
I love your work , we need more courses in oncology like that
It's a trually an amazing vdo with literally simple and very understanding concept ....Thanku so much for making it interesting...
Easy to understand and clearly explained
What an incredible video bro.
Once again I've come to The Master's Page for succinct and lucid clarification.
at 10:46 i almost thought that my laptop hanged up ... 😅 btw your lectures saves us from big thick textbooks revision
This video is very amazing and easy to understand.
One of the best pharmacology video I ever seen ty so much...
Awesome work, I very much enjoy watching your videos!
Very clear and wonderful video. Thanks a lot Armando 👏👏👏👏
Very helpful 😃. Thank you .Please where's the other video on hormones as an anti cancer drug class?
You helped me so much! Thank you!!! You're so clear and succinct.
You're one of a kind, thanks your video really helped me a lot to understand many things in my lesson
Great video & illustrations that really help in understanding these complex concepts. Thanks a million!!!!
4:44 is when he starts talking about alkylating agents
Thank you!!
Very nicely explained .. it's very difficult topic but u cleared all concepts thanks a lot.
Very clear presentation
May God bless you so much!!!
I have watched this video at least 15 times. Thanks you so much, excellent explanation. Just wondering if the video on hormonal agents was ever made?
U have deep understanding of pharmacology and genetics
Thank you very much. Very useful and necessary information.👍
Such a beautiful lecture 👏👏loved it
CRYSTAL CLEAR EXPLANATION OF ANTICANCER AGENTS!💞
This is wonderful. Thank you!
Online classes suck but this here cleared my concepts😀❤️❤️
Best youtube Pharmaology tutorials !!!!
Thank much!!! You don't know how much you facilitate the process for us, please going (Y)
Amazing presentation! Thanks for creating it. Truly helpful!
Thank you for making it easy to understand.
spot on descriptions, and easy to understand to boot!
you are incredible sir...the presentation is very nice and brief...make us easy to understand
Remarkable presentation
Oh my god 🔥 you are just insane sirr ✨
little correction: Adenine, Guanine,.... are not nucleotides, they are bases. AMP, GMP,... are the nucleotides.
You are genius sir respect for you
Thanks for the Video.. Amazing Explanation.💌
Hey Armando.. Thanks for the great video! Is there any way I can get a printout of this drawing?
Very well explained. Thank you very much
Very easy to understand
This is really helpful. BIG THANKS!
This is the most creative video I have ever seen on TH-cam..
Good explanation.
THANKYOU SO MUCH! IT'S REALLY HEPLINGFULL
Phenomenal video
Thank you so much .... it's video making ..in all steps clear to understands...and succinctly
Thank you universe
Thank you very very much.
Thank you for making this
Thank you soooo much🫶🏽🫶🏽🫶🏽❤❤❤
Thank you so much 💖
Thank you as always for these great videos
This is Brilliant!! Thank you so much sir 🙏🏻
Great video, thank you!
감사합니다 정말...
Thank you so much sir!
OMG THIS SAVED MY ASS. I’ve exam tom. 😂
Thank you ❤❤❤
Did you really draw all that? .. it's really good
Wow! I finally understood these :) Thank you so much :) Your videos are amazing 💜
it's so easy to understand...thz u so much
Wooow thanks for that effort. Its impressive ❤️🌹
Before I ask anything, your videos have helped me a lot with my essay about chemotherapy, so thank you for that! However, one youtube video isn't much of a source and I find it hard to find good scientific sources who go by the basics before getting specific. I see the link in the descriptions, but do you perhaps have a list with papers/chapters you've used?
Totally helpful...
But, I think small mistake is there, it's alkylating agents not alkalating...thank you.
Thank you so much....it really helped 😊
great one
Just wow !
good job
thank you great job
🎊🎊 amazing work!!