#81 - Muscle recovery after joint injury with Dr Chris Fry

Dr Glenn McConell chats with Associate Professor Chris Fry from the University of Kentucky, USA. Joint injury causes muscle weakness and atrophy (reductions in muscle size) due to the the inactivity but also separately due to the injury itself. Substances are released from muscle to help repair the joint/bone. Prehab is important before surgery. There can be residual effects long after joint injury. We also discussed hypertrophy and aging and the importance of having a lot of muscle capillaries as age to obtain the optimum response to resistance training. Lots more. We had a really great chat. Chris has a very pleasant manner. I enjoyed it a lot. Twitter: @ChrisFryPhD
0:00. Introduction and welcome
3:09. How Chris got into exercise research
6:10. ACL injuries and muscle wasting /weakness
9:05. Joint injuries and the risk of arthritis
10:05. The effects of the inactivity vs the injury itself
13:55. Protein synthesis vs breakdown after an ACL injury
19:30. Why in evolutionary sense does joint injury result in muscle atrophy
22:50. What are the signals to cause muscle atrophy
24:00. Myostatin release after joint injury
26:55. Acute vs chronic injury
28:15. Other joint injuries to joints (other than ACL)
29:25. Atrophy in different muscle fibre types
31:15. Best way to prepare for surgery after an injury
34:05. How quickly start rehab after surgery
35:45. Are there residual effects long after joint injury?
39:55. Bone vs joint injury
43:30. Muscle reactive oxygen species/ mitochondria after injury
46:05. Aerobic capacity of muscle still reduced after rehab
47:05. Should take anti inflammatories after injury?
49:20. Vitamin D and muscle injury
52:15. Does joint injury affect muscle in the non injuried limb?
54:45. What can do to slow atrophy after injury?
55:55. Does muscle size and strength go hand in hand after injury
57:15. Time since injury/trauma and surgery
58:55. Sex difference and joint injury
1:00:20. Age and joint injuries
1:01:10. Hypertrophy and aging
1:02:05. Aging: inactivity vs training response
1:03:00. More capillaries in muscle increases response to resistance training
1:05:00. Aerobic pre conditioning can help with hypertrophy
1:08:30. Anabolic resistance and aging
1:12:25. Connective tissue and training responses with aging
1:15:20. Satellite cells and muscle growth
1:17:45. Takeaway messages
1:19:01. Outro
Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.
The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.
He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (link.springer.com/book/10.100....
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Not medical advice

[@fraktaliaful]

Fantastic

[@kostaspapazoglou2851]

Very valuable and reassuring for those who are serious about their health and well-being. For those who cross-train hard and consistently, occasionally get injured and apply the methodologies and logic expounded in the discourse with your guest. Cheers!

[@Second247]

When talking of muscle size i'm always reminded of study that i read looking at crosscountry skiers and musclefibers in their their quads and triceps. They had very big type IIA fibers in their triceps, which had similar capillar density to type I fibers, but they were something like 1,5-2 times as big. Musclefibers had build more capillaries, unlike quads which had much more clear cut difference between type II and type I fibers, both clearly remaining in their specialized role. I think they hypothesis was that their triceps require both good aerobic performance and high strength output.
This would be really interesting to see studied on some all-rounder cyclists who actually need to be able to sprint and ride at threshold. Do their musclefibers it their quads display the same.
I lack the knowledge to put that into context. It would be interesting to compare that to strength atheltes, how big were their musclefibers really.
Bodybuilding is interesting case overall because there are some quite taxing high volume workouts which some of them do. If sprint interval training increases capillary density the best, as some researchers have said, then bodybuilders often already do that. Myoreps (15reps to bordering failure and then just enough rest to be able to finish 5reps) and long 20 rep sets fit the timedomain quite nicely.
But what i've listened to research world around bodybuilding i don't think this has been studied all that much.

[@insideexercise]

Interesting. I’m not sure either. Did you see that episode with Wim Derave? It’s likely he would know about these points.

[@Second247]

@@insideexerciseI might have missed that one
EDIT: Yeah, i've listened that one. But it was so good that it deserves another listen!