Rhonda Patrick: Nutrigenomics, Epigenetics, and Stress Tolerance

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  • เผยแพร่เมื่อ 13 มิ.ย. 2024
  • Our genes influence the way we absorb and metabolize micronutrients. Nutrigenomics looks at the influence genetic variation has over micronutrient absorption/metabolism and the biological consequences of this dynamic relationship. Our diet also influences which of these genes are turned on or off! Emerging evidence in the field of epigenetics has demonstrated that not only can we change the expression of our own genes within our own lifetime; sometimes these changes are heritable and affect our children and grandchildren. In this talk we’ll be exploring the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.
    Rhonda Perciavalle Patrick, Ph.D. is an assistant scientist at Children’s Hospital Oakland Research Institute working with Dr. Bruce Ames. She investigates the effects of micronutrient (vitamins and minerals) deficiencies on metabolism, inflammation, DNA damage, and aging in people. She also researches the role of vitamin D in brain function and dysfunction.
    In addition to Rhonda’s active role as a researcher, she also functions as a science communicator for a broad lay audience via her web and video presence found at FoundMyFitness.com. She is passionate about disseminating health-related information in a way that the general public can easily understand. She is a frequent speaker and writer on topics ranging from general health and wellness, to diet and aging, to vitamins and their effects. It is Rhonda’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.
    Rhonda earned her Ph.D. in biomedical science from the University of Tennessee and performed her graduate research work at St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California, San Diego. She has done extensive research on aging, cancer and nutrition, and metabolism

ความคิดเห็น • 111

  • @Countauguste
    @Countauguste 2 ปีที่แล้ว +1

    Dr. Rhonda has a sense of humour. She spews out faster than the mind can bear. Cheers!

  • @eCitizen1
    @eCitizen1 3 ปีที่แล้ว +4

    We are so lucky to have Dr. Rhonda Patrick, how else would we learn this stuff? Awesome talk, and an awesome speaker. I set the playback speed to 0.75 to help with absorption (hehe).

  • @jamesart9
    @jamesart9 7 ปีที่แล้ว +20

    Aside from the wonderful content, Rhonda's presentation is absolutely brilliant.
    She knows her stuff inside and out and is not reading from a script, just sharing what she knows. (A Lot.)
    Wonderful stuff.

  • @christopherellis2663
    @christopherellis2663 5 ปีที่แล้ว +12

    I tend to eat during a four hour window, in the afternoon. As I was recently travelling, I did not eat for forty hours. This is, in my opinion, the normal way to eat. I am in my seventieth year. 🇷🇴 I also enjoyed several hours in the Széchenyi Spa in Budapest 🇭🇺 mainly going between the cold pool and Vulkán Szauna, set at 80 C. Both were lovely.

  • @poosta7
    @poosta7 7 ปีที่แล้ว +21

    Awesome presentation(s) !!! I have a PhD i Biology and have heard many experts present on their area of expertise...Dr. Patrick is the best I have ever experienced.

  • @absbi0000
    @absbi0000 ปีที่แล้ว

    Amazingly accessible information. Thanks Dr. Rhonda Patrick 👍

  • @jhughes911
    @jhughes911 9 ปีที่แล้ว +52

    POWERFUL Rhonda Patrick!

  • @FoundMyFitness
    @FoundMyFitness 9 ปีที่แล้ว +27

    I've actually put together a really great PDF that summarizes absolutely everything and adds references to what I talk about in the above video… if any of you guys are partial to that sort of thing you can get it here: www.foundmyfitness.com/?sendme=lifestyle-heuristic
    Special thanks to the IHMC for having me out. Getting to meet ATLAS and see some of the amazing things going on down there in Pensacola was a LOT of fun.

    • @watersNO9
      @watersNO9 9 ปีที่แล้ว +4

      FoundMyFitness you are insane! I'm training to be a Nutritional Therapist, and listening to your podcasts and videos makes me so much smarter than the rest of the class! Can you please do some talks on Inflammatory Bowel Disease i.e. Crohn's Disease. I have been diagnosed with it, and since listening to your supplementation advice my symptoms have improved 10 fold!

    • @venuthottathil1
      @venuthottathil1 8 ปีที่แล้ว

      Sexygirls

  • @johnteran8889
    @johnteran8889 9 ปีที่แล้ว +8

    Both you and Dr Ames at the IHMC. That's enough to vet this organization twice over.

  • @VincyMan
    @VincyMan 8 ปีที่แล้ว +10

    What an excellent presenter of such critical information! You have provided a day's information in less than one hour. Well worth viewing multiple times!

  • @_jamesbradley__
    @_jamesbradley__ 5 ปีที่แล้ว +5

    Excellence in communication and knowledge. Thank you so much.😎👍

  • @sylvialeftin5094
    @sylvialeftin5094 2 ปีที่แล้ว

    Thank you Dr. Patrick for your amazing resesrch findings!!!
    Shalom,
    Sylvia Leftin

  • @arnsteinholm7372
    @arnsteinholm7372 6 ปีที่แล้ว +2

    Epigenetic analyses will reveal more and more stunning knowledge which in turn will emerge into a broad spectral range of innovative opportunities for managing age related epigenetic controlled illnesses in a much more efficient and sustainable way .... especially compared to the more or less ineffective and inhumane mainstream cancer treatments which still in use ... which probably kills hundreds of thousands each year :-( You have both the skills and matching pedagogic explanations regarding your thorough knowledge about nutrition related epigenetics ... thank you so much Dr. Rhonda !! :-)

  • @Kirsten_is_cursed10
    @Kirsten_is_cursed10 5 ปีที่แล้ว +2

    This woman is the reason I want to be a doctor 👏🏻

  • @Heroqualle9
    @Heroqualle9 6 ปีที่แล้ว

    What a great time to be alive and being able to watch this. Thank you! :)

  • @samjam7546
    @samjam7546 7 ปีที่แล้ว +4

    Great introduction to nutrigenomics. Thank you Dr. Patrick

  • @haileyrowe793
    @haileyrowe793 7 ปีที่แล้ว

    Amazing insight and presentation. I LOVE Dr. Rhonda Patrick.

  • @sweetmintkiss
    @sweetmintkiss ปีที่แล้ว

    She knows what she is doing looking like a teen at 45y.o. amazing speech ❤️

  • @lyleburns8532
    @lyleburns8532 2 ปีที่แล้ว

    I love Rhonda "get your vitamin D!" Patrick!!!

  • @NataliesImperfectJourney
    @NataliesImperfectJourney 9 ปีที่แล้ว +26

    Smart chicks rock!!! Awesome presentation!

  • @suziealt6842
    @suziealt6842 5 ปีที่แล้ว

    I love listening to and learning from you!

  • @tehgreg2
    @tehgreg2 9 ปีที่แล้ว +2

    Greatest commercial for science I've ever seen. You've spent a lot of time and resources on this. Awfully nice of you to share. Thanks.

  • @peterpham9813
    @peterpham9813 7 ปีที่แล้ว +7

    Thank you Dr. Patrick for this valuable info. Our multiple systems slows down with age among the causes are free radicals. Activate the NrF2 pathway to promote the gene expression to produce anti-oxidants from within our cells to remove free radicals and activate the NrF1 pathway to restore the mitochondria optimum efficiency for ATP production are vital for our body to expand its longevity through keeping things in balance.. The technology already exists.

    • @brownboysgolf
      @brownboysgolf 7 ปีที่แล้ว

      Peter Pham pro T :)

    • @mv8908
      @mv8908 2 ปีที่แล้ว

      Cruciferous am I right

  • @WYLOEvelin
    @WYLOEvelin 7 ปีที่แล้ว

    Rohnda, thank you! Very, very powerful!

  • @googleone9209
    @googleone9209 8 ปีที่แล้ว +2

    So relevant and high yield Dr. Patrick!

  • @michelbisson6645
    @michelbisson6645 5 ปีที่แล้ว

    Wonderful presentation as usual so brilliant...

  • @josemiguelmandolesi4199
    @josemiguelmandolesi4199 6 ปีที่แล้ว

    I love watching her videos.

  • @kirillgedde3645
    @kirillgedde3645 5 ปีที่แล้ว

    Thanks for your work!

  • @eternal_stoic_
    @eternal_stoic_ 3 ปีที่แล้ว

    I wish I could have her as a profesor, teacher or something. She is amazing

  • @mcbowler
    @mcbowler 9 ปีที่แล้ว

    amazing info here. thanks!

  • @dennismcgraw9659
    @dennismcgraw9659 5 ปีที่แล้ว

    We love your videos!!

  • @jameswalsh8816
    @jameswalsh8816 3 ปีที่แล้ว

    Always love your videos Rhonda. Incredibly intelligent and gorgeous woman!!

  • @anthonydmorse
    @anthonydmorse 5 ปีที่แล้ว

    Mind Blown!!

  • @lilacosmanthus
    @lilacosmanthus 7 ปีที่แล้ว +1

    This is such an important presentation. More people need to see it.
    Shared.

    • @g.s.5868
      @g.s.5868 6 ปีที่แล้ว

      1) people are afraid to skip 1 meal
      2) people are too addicted to their carbs
      3) people prefer to inject themselves with insulin than to give up the food that is causing their illness

  • @albertouribe435
    @albertouribe435 5 ปีที่แล้ว

    Thank you

  • @TheToothGoose
    @TheToothGoose 7 ปีที่แล้ว +1

    31:36 - Dr. Patrick delivers a prophesy while in a trance state.

  • @whiteeagle5969
    @whiteeagle5969 4 ปีที่แล้ว

    Rhonda you are stellar! - intellectually of course

  • @BenDickey
    @BenDickey 9 ปีที่แล้ว

    Thanks.

  • @jackbravo8496
    @jackbravo8496 8 ปีที่แล้ว +1

    Does isolated protein,such as in a protein shake, intake lower NAD as well or just fats and carbs? And if it does, is it dose dependent or threshold dependent?

  • @giankolbjornsen
    @giankolbjornsen 5 ปีที่แล้ว

    Rhonda, thank you! A very clear, informative and interesting explanation. Well done.

  • @macjoyjoy
    @macjoyjoy 6 ปีที่แล้ว

    Regarding 5:40 - What happens if you take Collagen Peptides which contains Proline? Is that a proper go-around way to mitigate that problem?

  • @paulcohen6727
    @paulcohen6727 8 ปีที่แล้ว +1

    There have been two studies involving monkeys and calorie restriction. One, done at the University of Wisconson, found that thin monkeys (who were calorie restricted) had fewer medical problems than obese monkeys who could eat all they wanted, and so, the thin monkeys lived longer than the obese ones. So, this proved nothing that we didn't already know. Obesity often shortens lives. However, what would happen if calorie restriction was compared to a prudent healthy diet of normal calorie content? This experiment was done on monkeys at the National Institutes of Aging and it found that there was no difference in life span; calorie restriction only annoyed the monkeys who were subjected to it. In addition, when people went into the animal's quarters, they had to wear surgical masks to avoid spreading microbes to the monkeys? Why? because calorie restriction depresses the immune system, making it impractical in the real world. It may also weaken bones and muscle. I've seen six-footers on calorie restriction who only weight 130 pounds. You call that healthy?

  • @lt9316
    @lt9316 4 ปีที่แล้ว

    What a brain she has!!!

  • @Hevlincris
    @Hevlincris 5 ปีที่แล้ว

    Awesome

  • @823850
    @823850 8 ปีที่แล้ว +1

    I'm intrigued by the fact that beta carotenes are fat soluble and better used when eaten with fat. I can't get myself to eat carrots or bell peppers by themselves. But some additive-free peanut butter as a dip or spread, and I've got a meal. Now I'm wondering if I was sensing something.

  • @Kitopa
    @Kitopa 4 ปีที่แล้ว

    I fucking LOVE rhonda patrick

  • @lt9316
    @lt9316 4 ปีที่แล้ว

    How can we get access to her reports?

  • @badmojjo
    @badmojjo 5 ปีที่แล้ว

    52:40... very nice! A woman asking questions about men issues, very nice, thank you :)

  • @attractiveness999
    @attractiveness999 9 ปีที่แล้ว

    i love you rhonda

  • @sponusic9878
    @sponusic9878 8 ปีที่แล้ว

    Regarding the question about how do we know that our nutrients are being utilized well... See the Fenech study, Carcinogenesis 2005; 26(5): 991. High levels of some nutrients led to genetic destabilization (B2, B5, biotin, some of this related to folate deficiency), while supplementing high with others proved positive.

  • @failyourwaytothetop
    @failyourwaytothetop 2 ปีที่แล้ว

    Autophagy seems to contradict what she says. Fasting for days on end from another lecture I saw has benefits of regeneration and elimination of residual cellular components not removed from the normal biological waste systems. That lecture highlighted the benefits of every once in a while about 2 to 3 times a year the necessity of multiday fasts. It would be interesting if she would address and respond to this.

  • @sponusic9878
    @sponusic9878 8 ปีที่แล้ว +4

    Loved your video BUT, with all the talk about magnesium and vitamin D, you didnt explain the vital role of magnesium in converting 25OH )vitamin D to the active form. This is what we nutritionists think about....

    • @sponusic9878
      @sponusic9878 8 ปีที่แล้ว +1

      You need to check out how magnesium is vital in converting the pro-hormone into the active hormone, 1,25 dihydroxyvitamin D.

    • @hikerJohn
      @hikerJohn 5 ปีที่แล้ว

      Why no response to SaysRobert's good question? Did you find one on your own?

  • @highvoltage5933
    @highvoltage5933 4 ปีที่แล้ว

    Brilliant job rhonda are statins involved in anyway with changing the way we consume and obsorbe nutrients from what we eat or do they change our dna in anyway. and it's true what they say you are what you eat 😁 👍👏

  • @boogihoff
    @boogihoff 9 ปีที่แล้ว

    Interesting. You would love Dr Joel Wallach...he has several books but the two I am thinking are Epigenectics and Dead Doctors Don't Lie😀y'all will love his research!

  • @Percyfaith7
    @Percyfaith7 6 ปีที่แล้ว

    Rhonda Patrick mentioned 60 as an optimal Vit D level I have heard between 60 and 80 are optimal. Not sure she mentioned not good to be over 60 and I am wondering her reasoning. Anyone seeing this know how to determine our own optimal D level?

    • @qthirteen13
      @qthirteen13 5 ปีที่แล้ว

      Martha Ray look up Ivor Cummings... has done some good work in Vitamin D area

  • @hikerJohn
    @hikerJohn 5 ปีที่แล้ว +1

    Once this is really understood I bet you could manipulate gene expressions to reduce risk to older couples wanting to have children.

  • @SotirisVenetis
    @SotirisVenetis 5 ปีที่แล้ว

    at 32.24..she says INTERMIDIATE FASTING FOR 48 hours....does this mean eating in a window of 8 hours or once a day..and after 48 hours this will be activated...?OR it means intertemidate fasting..EATING EVERY 48 HOURS..so taht after 48 hours of not eating at all...and you will get teh autophagy benefits....?

  • @agent7224
    @agent7224 7 ปีที่แล้ว +2

    HI RHONDA PATRICK. I DIDN'T EVEN KNOW WHAT NUTRIGENOMICS... DIDN'T EVEN KNOW IT EXISTED! SO HOW MUCH VITAMIN D CAN MY FRIEND TAKE? HE'S 186 POUNDS, ATHLETIC. THANK YOU. YOU ARE AN AWESOME HUMAN BEING!!

    • @wdalence
      @wdalence 7 ปีที่แล้ว +1

      Agent 722 blood test... she said

    • @agent7224
      @agent7224 7 ปีที่แล้ว

      k thx walther!

    • @qthirteen13
      @qthirteen13 5 ปีที่แล้ว

      Agent 722 look at Ivor Cummings work into Vitamin D... we should probably be getting 4000IU a day at minimum.

  • @dwightjessup507
    @dwightjessup507 8 ปีที่แล้ว

    So -- Rhonda, are you willing to share your Power Point?
    BTW I am a patreon.

  • @ReeferMadman
    @ReeferMadman 4 ปีที่แล้ว

    All hail Ming! I mean Mrs Rhonda!

  • @nobodynothing2594
    @nobodynothing2594 ปีที่แล้ว

    She looks the same even now 8yrs since this video 😮

  • @peacefulpony
    @peacefulpony 9 ปีที่แล้ว +7

    Kind of hard to watch this and not load up 23andme to flirt with the "order now" button.

    • @sponusic9878
      @sponusic9878 8 ปีที่แล้ว +3

      23andme is a great tool but you need to use other apps to interpret- she metioned Promeathese but I dont personally care for that one.; easy one is Genetic Genie, then Sterling's MTHFR support, Nutrihacker; Livewello, even then there is much to learn--- it's about the time you want to invest ...you could try start with a couple major genes like MTHFR, COMT, PEMT, SUOX, etc.

    • @hikerJohn
      @hikerJohn 5 ปีที่แล้ว

      Thanks for this reply

  • @bshef3424
    @bshef3424 6 ปีที่แล้ว +1

    "SCIENCE" :)

  • @sponusic9878
    @sponusic9878 8 ปีที่แล้ว +4

    when you up the vitamin D supplement you deplete mg stores... and what about vitamin A and other fat soluble supplements and their role in vitamin D binding to receptor? there are consequences of taking too much D! This alone wont solve the problem.

    • @peytonrivers7526
      @peytonrivers7526 8 ปีที่แล้ว +1

      In another video Rhonda says the proper vitamin D dose is 30-60IU/day, and that you don't want to go below or above it.

    • @carlosfernando7552
      @carlosfernando7552 7 ปีที่แล้ว

      carlos Fernando #@#98632

    • @user-cm9ef4fw7m
      @user-cm9ef4fw7m 6 ปีที่แล้ว

      SP Onusic idiot

    • @sharmannobody7889
      @sharmannobody7889 5 ปีที่แล้ว

      Dickhead.

    • @cha55am
      @cha55am 5 ปีที่แล้ว

      Tony Tiller one or two abusive comments here. You should be ashamed of yourselves

  • @LasVegasSand_s
    @LasVegasSand_s 4 ปีที่แล้ว +1

    31:01

  • @dangheck
    @dangheck 9 ปีที่แล้ว +1

    Please do an ama on reddit. Please!!!

    • @FoundMyFitness
      @FoundMyFitness 9 ปีที่แล้ว +4

      Silver Mean I actually did a couple of "Author AMA" sessions on /r/science when some of the papers I authored were posted there.
      Part 1...
      www.reddit.com/r/science/comments/1yk41h/in_faseb_journal_today_serotonin_oxytocin_and/
      Part 2...
      www.reddit.com/r/science/comments/2x4k39/omega3_and_vitamin_d_may_control_brain_serotonin/

    • @dangheck
      @dangheck 9 ปีที่แล้ว +2

      I didn't think to search outside r/ama ! Thanks!

  • @truthtrekker
    @truthtrekker 5 ปีที่แล้ว +1

    Good for Rhonda Patrick. Another thinker confirms at 37:00 what HeLa cells have taught us already: Human Cells are Immortal. Immortal means that you never die. Death is a grave mistake. The energy of the dead goes back inside of the Sun.

    • @absbi0000
      @absbi0000 4 ปีที่แล้ว

      truthtrekker the sun is slowly dying

    • @truthtrekker
      @truthtrekker 4 ปีที่แล้ว

      @@absbi0000 *Next thing you'll be telling me is that there is an invisible man living in a castle on a cloud in the sky and that a woman can bear a male child without a load of sperm.*

  • @Ironmurs
    @Ironmurs 2 ปีที่แล้ว

    This woman is the most beautiful cyborg evers. Love you Doc 😘

  • @thejerryj
    @thejerryj 8 ปีที่แล้ว

    I understand that the obese male mouse had offspring that the offspring was type I diabetic. If that same male mouse were to return to a normal weight would his offspring still be diabetic?

  • @arcidiavolo
    @arcidiavolo 8 ปีที่แล้ว +1

    yeah. but how they wiped out vit d receptors in that mouse? with poison of some kind perhaps? or one by one?

  • @brandonbigisland844
    @brandonbigisland844 9 ปีที่แล้ว +7

    why cant they make all women like this?

    • @qthirteen13
      @qthirteen13 5 ปีที่แล้ว

      Brandon BigIsland too many fall into the vegan bandwagon...sadly

    • @marynordseth2788
      @marynordseth2788 5 ปีที่แล้ว

      you pig

  • @paulgent9203
    @paulgent9203 5 ปีที่แล้ว +3

    Can’t work out weather she’s over smart or over hot. Just saying

  • @davidstrong7854
    @davidstrong7854 5 ปีที่แล้ว +3

    These people that all they think about is supplements. Why not tell them to supplement with WHOLE FOODS

    • @qthirteen13
      @qthirteen13 5 ปีที่แล้ว

      David Armstrong cause her middle name is Supplement and Sulphuropane....lol
      Whole foods aren’t as profitable. ;-)

    • @hikerJohn
      @hikerJohn 5 ปีที่แล้ว

      She does all the time - just not in *every* lecture. So what do you mean by "These people"?

  • @MattBuysHouse
    @MattBuysHouse 3 ปีที่แล้ว

    Who's this fox? 🦊,

  • @mauimike81
    @mauimike81 4 ปีที่แล้ว

    I wonder why her face looks so greasy. Maybe diet.

    • @eCitizen1
      @eCitizen1 3 ปีที่แล้ว

      I'm guessing she has one of the best diets of anyone ever. Harsh lighting is more likely.

  • @Countauguste
    @Countauguste 2 ปีที่แล้ว

    Dr. Rhonda has a sense of humour. She spews out faster than the mind can bear. Cheers!