2022 University of Manitoba Gairdner Lecture by Dr. Pieter Cullis

Dr. Pieter Cullis, 2022 Canada Gairdner International Award winner presented at the University of Manitoba for the Annual Gairdner Lecture - Science and Serendipity: Lipid Nanoparticles that Enable COVID-19 MRNA Vaccines.

[@maxentropy7596]

At 40:00 Cullis states that he got a phone from presumably BioNTech in 2017. But interestingly his next statement skips to 2020. What was Cullis working on in the intervening 3 years?

[@brucemoose926]

NMR is rebranded as MRI for use in medicine because the word nuclear would scare off most people.

[@lieneke3108]

Mr. Cullis, such a great explanation of it all. And what an achievement! I heard you say the LNP cannot be targeted yet (other then being taken up by the liver…). Can you then explain to me how they promised the SARS Cov2 mRNA being uptaken by dendritic cells only? And my second question is: if they indeed cannot be targeted as you say, how are other cells prevented to be attacked by it’s own immuunsysteem (iow: prevent auto-immunity)?

[@EmJen-dl7rr]

Uptaken by Dendritic cells only?

[@robt8042]

46:18 admits it's not able to target and basically no answer to this problem. Meanwhile just experiment on the world population until you work it out. Unbelievable.

[@coolgamegamecool2291]

can not hear the questions. please post the questions.

[@msheart2]

Virus oh right those things, extracellular debris..