Hi there! Around 4:30, you mention parathyroid hormone being at a "good ratio" with vitmain d level - what would you suggest might be an ideal PTH to vitamin d level? for example, I am well over 150 ng/ml (max number my test goes to), yet my PTH is 33. I would personally have expected PTH to be lower for such a high vitamin d level, so my thinking is this indicates vit d resistance. Would love to hear your thoughts.
Great topic. I have few questions on this. So increased PTH levels with normal vit d levels are the way to diagnose vid D resistance. What about scenarios where PTH is elevated for diferent reasons while vit is normal? In the presence of autoimmune, why not suplement high dose vit D anyway? Also woukd genetic VLDR mutations predispose to issue. Lastly why would vit D cause flare in chronic patients? Could it be possible vit D lowering blood calcium increases circ oxylates thus symptoms?
I have Mast Cell Activation and Ive been taking 10.000 UI vitamin D dose daily for a year and my PTH level increased and calcium decreased, maybe a higher dose would be better.
Wondering if a genetic variant like I have might contribute to this issue / be an indicator for trialing the protocol despite having a 'normal' lab level? Quoting from Dr Rhonda Patrick's analysis of my 23andMe data - "The variant form (T) of the rs7041 polymorphism is thought to result in a protein that binds less efficiently to vitamin D. The (G;T) genotype may increase the risk of Vit D deficiency."
great convo, i learned a lot
Hi there! Around 4:30, you mention parathyroid hormone being at a "good ratio" with vitmain d level - what would you suggest might be an ideal PTH to vitamin d level? for example, I am well over 150 ng/ml (max number my test goes to), yet my PTH is 33. I would personally have expected PTH to be lower for such a high vitamin d level, so my thinking is this indicates vit d resistance. Would love to hear your thoughts.
video reply is on the way!
@@halifaxnaturopathicdoctor6227 Can't wait, thank you so much!!
Great topic. I have few questions on this.
So increased PTH levels with normal vit d levels are the way to diagnose vid D resistance.
What about scenarios where PTH is elevated for diferent reasons while vit is normal?
In the presence of autoimmune, why not suplement high dose vit D anyway?
Also woukd genetic VLDR mutations predispose to issue.
Lastly why would vit D cause flare in chronic patients? Could it be possible vit D lowering blood calcium increases circ oxylates thus symptoms?
Great questions, as always - video reply is forthcoming :)
Hi, could high dose of vitamin D3 work for mast cell activation as well?
Could it be NAFLD (non-alcoholic fatty liver disease) which make the vit D resistance?
good question. I haven't heard of this link. What mechanism of action do you think might link the two?
I have Mast Cell Activation and Ive been taking 10.000 UI vitamin D dose daily for a year and my PTH level increased and calcium decreased, maybe a higher dose would be better.
Interesting. I'm posting a video regarding this later today or tomorrow.
Wondering as well if supplementing with K2 helps to counter potential increases in calcium levels?
Dr. T has told me it doesn't really matter. I had the same thought as you...but she's the expert!
Wondering if a genetic variant like I have might contribute to this issue / be an indicator for trialing the protocol despite having a 'normal' lab level? Quoting from Dr Rhonda Patrick's analysis of my 23andMe data - "The variant form (T) of the rs7041 polymorphism is thought to result in a protein that binds less efficiently to vitamin D. The (G;T) genotype may increase the risk of Vit D deficiency."
Orthomolecularmedicine