The $140 Mail-Order CRISPR Kit: Is Unregulated Biohacking the Future of Science?

แชร์
ฝัง
  • เผยแพร่เมื่อ 19 มิ.ย. 2016
  • What happens when you democratize science and give anyone the ability to edit DNA?
    Subscribe to Reason TV for daily content like this: bit.ly/1Ocr2AL
    See the full text at Reason.com: reason.com/reasontv/2016/06/17...
    MORE VIDEOS LIKE THIS:
    3D Printing DNA and Hacking Life's Code:
    • 3-D Printing DNA: Hack...
    WHAT OUT OF CONTROL BIOHACKING MEANS FOR THE FUTURE:
    • What "Out of Control" ...
    ---
    "Are people dying and suffering needlessly because of all these committees and all these rules?" asks Josiah Zayner, a scientist, biohacker, and founder of the biotech company The Odin, which supplies low-cost CRISPR kits for the consumer market. "And what if people just say, 'F- you, I'm going to do it anyway'? And what if people start getting cured?"
    CRISPR is a gene editing system that allows scientists to modify the DNA of organisms ranging from bacteria to plants and fungus to human beings. The Odin sells kits for the the modification of bacteria and yeast.
    Reason TV visited Zayner in his garage lab to discuss the implications and ethics of bringing CRISPR to the masses, why he left a prestigious job in a NASA laboratory to start his own company, how regulation stifles scientific innovation, and why he believes that unregulated, decentralized experimentation will lead to the some the next great scientific breakthroughs.
    Watch the full interview above, or click below for downloadable versions. Approximately 10 minutes. Produced by Zach Weissmueller. Camera by Alexis Garcia. Music by Kai Engel.

ความคิดเห็น • 1.1K

  • @marcosbeni5875
    @marcosbeni5875 8 ปีที่แล้ว +260

    1:45 Very accurately describes my job as a contractor for the military. Government is only good at creating large bureaucracies to waste money, resources, and talent.

    • @BruceThomson
      @BruceThomson 7 ปีที่แล้ว +35

      I worked in six different govt. departments here in New Zealand, and sympathize. There was this joke... How do you create a govt department? You get a huge stadium, carpet it, set up hundreds of desks, dividers, phones, meeting rooms, computers, intranet. Seal all the doors except for one. From outside, open that door. Toss in a memo. Close the door.

    • @bhbluebird
      @bhbluebird 7 ปีที่แล้ว +3

      Marcos Beni same here. his description was dead on point

    • @Donaldo
      @Donaldo 7 ปีที่แล้ว +5

      Happens in private sector, too.

    • @rickflair6250
      @rickflair6250 7 ปีที่แล้ว +2

      Marcos Beni nnmu

    • @___Truth___
      @___Truth___ 7 ปีที่แล้ว +4

      Donaldo thats a false equivalence. Some =! All . Unlike government. Where ALL are inefficient and Wasteful. Being wasteful is death to the private sector, while being wasteful is an overall function of government.

  • @oPHILOSORAPTORo
    @oPHILOSORAPTORo 8 ปีที่แล้ว +106

    "We're throwing science at the wall and seeing what sticks." - Cave Johnson

  • @sniper6081
    @sniper6081 8 ปีที่แล้ว +709

    Stuff like this will dramatically increase the rate of advancement in biotech and medical science.

    • @Lobos222
      @Lobos222 8 ปีที่แล้ว +21

      or bio terrorism...

    • @sniper6081
      @sniper6081 8 ปีที่แล้ว +31

      Lobos222 Really? You had to go the fear route? Do you ever get tired of being scared all the time?

    • @Lobos222
      @Lobos222 8 ปีที่แล้ว +17

      Buff Awesome
      I would argue you are petty naive if you think this isnt going to be regulated... There are reasons there are regulation on chemicals. Because while most dont make a bomb or similar, some might want to and regulation is put in place to prevent those with illegitimate intent to not gain access. This is the same type of thing. A double edge sword.
      This has nothing to do with fear. Fear is cowering in a corner. Shutting your eyes while driving and hope for the best is foolish. Having progressive regulation is sensible.

    • @sniper6081
      @sniper6081 8 ปีที่แล้ว +14

      Lobos222 You can't really regulate something that's decentralized. What's the government going to do? Go into every single house in the country to find all the people using this technology? The laws would be unenforceable. Uber is a perfect example of this. There's many place where their services are banned, but they continue to operate anyway. What's the government going to do? Check every single car on the road? That's the point this video made. it's not that the government won't regulate it. it's that they can't.

    • @Lobos222
      @Lobos222 8 ปีที่แล้ว +5

      Buff Awesome
      Uber is regulated just like the Taxi bis in some nations that have a properly functioning government. In one nation Uber actually shut down because they didnt get away with their social dumping bis plan of transferring the value of the car into money for the driver short term, while screwing him over long term because hes actually making less than it costs for him to drive because the hidden costs dont show up until later when he would need to swap out vehicles or similar...
      Yes, if you deal in drugs or whatever illegal activity at home. The police will come and shut it down. Nor would you have easy legal access to the ingredients at stores and so on.
      Btw how old are you, because you sound very young. Example: "You can't really regulate something that's decentralized." "What's the government going to do?"
      You really think its hard to shut down a person that drives in public for a living? That pays taxes and or does not pay taxes? If Uber was illegal and the government wanted to do something. They could impound the cars for illegal usage. Fine the drivers. Limit their license for X time etc... and if they continue. Put them in prison.
      Its like you are used to such a level of inaction you think it wouldnt be possible. LoL

  • @ZombieLicorice
    @ZombieLicorice 8 ปีที่แล้ว +585

    It is going to scare a lot of folks but we need more scientists like this. People willing to stand closer to fire to forge a better weapon.

    • @jeanrenetournecuillert2449
      @jeanrenetournecuillert2449 7 ปีที่แล้ว +1

      Totally agree

    • @craigleomegle2433
      @craigleomegle2433 7 ปีที่แล้ว +5

      Since its unregulated it has its pros and cons therefore people can bring back the black plague and others can find cures. It's beautiful to be honest pretty much like computer hacking.

    • @melvinjacobson6013
      @melvinjacobson6013 7 ปีที่แล้ว +3

      there still is a black plauge were just resistant to it cuz modern day penicillin

    • @roderik1990
      @roderik1990 7 ปีที่แล้ว +10

      Keyword, scientist, while the unregulated nature of something like this means there will also be tons of quacks and idiots using it.

    • @cyrilmani4169
      @cyrilmani4169 7 ปีที่แล้ว +5

      really well said man!

  • @supersonicdickhead374
    @supersonicdickhead374 8 ปีที่แล้ว +237

    the guy that invented the wheel had the same problem. Nobody was interested, fire was all the rage.

    • @nippernappertton
      @nippernappertton 6 ปีที่แล้ว

      Well to be fair, the guy that invented a good wheel, which required some intricate craftmanship and technological knowledge, had their culture and language spread through the steppe west and through europe following the Sun as god on it's four-wheeled carriage.

    • @illDefine1
      @illDefine1 5 ปีที่แล้ว

      Man harnessed fire 1.5 million years ago and the wheel was invented in its earliest stage 8000 years ago. According to your timeline, eternal life was all the rage.

    • @nGUNNARp
      @nGUNNARp 5 ปีที่แล้ว +3

      how does this comment have so many thumbs up? do people actually think that "the guy who invented the wheel" was shut down?

    • @kostailijev7489
      @kostailijev7489 5 ปีที่แล้ว

      Yeah right!

    • @shiki2540
      @shiki2540 3 ปีที่แล้ว

      @@nGUNNARp It's a joke

  • @user-gd5rr6kz2b
    @user-gd5rr6kz2b 7 ปีที่แล้ว +4

    My father quit NASA because of the same reason. When he got hired he was given an office but couldn't even log into the programs on his computer because he wasn't given login creditinals, so he spent his first month staring at a computer he couldn't use. Then when he finally got login creditinals and finally got to work his supervisor came to him and told him that he was working too much and to tone it down... apparently they are union and my dad was doing more work than what is required for them to do. He ended up getting so frustrated with the incredibly slow pace that they wanted him to work at that he quit and went back to his old job. I was blown away when he told me about how slowly things moved there.

  • @hathynhighley8548
    @hathynhighley8548 ปีที่แล้ว +2

    I was around 16 when i seen this. Dr Zayner showed me the path to becoming a biohacker. I did a couple of The Odin kits throughout the years and now im on my way to becoming an official bioengineer. Who would have thought.

  • @nikkiminajj47
    @nikkiminajj47 7 ปีที่แล้ว +2

    When is he going to release a "CRISPR for dummies" book so I can have super powers?

  • @deathpony698
    @deathpony698 7 ปีที่แล้ว +296

    all aboard the CRISPR hype train

    • @TheArabsolga
      @TheArabsolga 7 ปีที่แล้ว +12

      Lets fucking gooooo

    • @cerii5943
      @cerii5943 7 ปีที่แล้ว +4

      deathpony698 Hype Hype!

    • @Darksagan
      @Darksagan 7 ปีที่แล้ว +1

      HAHAHAHAHH

    • @bananaman6046
      @bananaman6046 7 ปีที่แล้ว +2

      deathpony698 YES YYEEES

    • @mathejoujou8492
      @mathejoujou8492 6 ปีที่แล้ว +3

      Neo Hungarian Barbarian you hate it while you understand literally nothing about it

  • @JoshuaFinancialPL
    @JoshuaFinancialPL 7 ปีที่แล้ว +24

    yeah that looks sanitary

  • @RaPiiDHUNT3R1
    @RaPiiDHUNT3R1 8 ปีที่แล้ว +149

    Real scientists provide value to the market like this guy, there's literally dozens of them, DOZENS!

    • @KevinP32270
      @KevinP32270 7 ปีที่แล้ว +1

      AGREED.

    • @abdulwardak4913
      @abdulwardak4913 7 ปีที่แล้ว +4

      An-Cap Edits DUDE TELL ME MORE PEOPLE!!!

    • @claudiusatlas8083
      @claudiusatlas8083 7 ปีที่แล้ว +18

      An-Cap Edits bullshit. Science is science, whether it makes people money is irrelevant.

  • @TheOkami1113
    @TheOkami1113 7 ปีที่แล้ว +43

    The fact of the matter is that unless you have at least an undergraduate-level knowledge of molecular biology and biochemistry experimental methods and design, a vast majority of these resources will be wasted. That's not to say that having access to Cas9 is pointless. It's just that you can't even begin to have a conversation about breakthroughs if, in fact, you don't understand the surface level stuff.

    • @6ghastlyghoul9
      @6ghastlyghoul9 7 ปีที่แล้ว +17

      TheOkami1113 You can find all information about biology and chemistry online. Who cares about a degree when you create something that actually works?

    • @fireteamomega2343
      @fireteamomega2343 7 ปีที่แล้ว +10

      There's enough resources online for those who are inclined to learn to become masters at nearly anything. This kit along with a centrifuge a few basic reagents rnases dnase and a cell culture kit can do amazing things even in an amateurs hands. Agreeably it is helpful to have someone walk you through the current processes. But imagine what you could've spent that 60k on had you the knowledge you spent it on.

    • @Aaron565
      @Aaron565 6 ปีที่แล้ว +1

      Guess giving children modular computer toys is also useless. Guess reading a DIY tutorial to breed plants is also impossible too.

    • @curvingfyre6810
      @curvingfyre6810 6 ปีที่แล้ว

      the main goal is to streamline the process for the user, which is being done by people who do have that education, so that individuals already working in fields of interest, like that beer brewer, can innovate on their own time, using their own experience and market knowledge. whats a scientist going to know about what makes beer high quality? thus, giving them the job is going to waste time and resources, even though there is undoubtedly good money in it. the same analogy applies to most fields.

    • @jshricks
      @jshricks 4 ปีที่แล้ว

      Bah, old school belief. There is the internet which easily replaces college.

  • @unzensiert7339
    @unzensiert7339 8 ปีที่แล้ว +8

    I can't wait doing this stuff and exploring virtually a new world.

  • @jakefrye3363
    @jakefrye3363 8 ปีที่แล้ว +419

    That was awesome, this guy needs a youtube channel or something

    • @MrBillz714
      @MrBillz714 8 ปีที่แล้ว +6

      name please?

    • @holdmybeer
      @holdmybeer 8 ปีที่แล้ว +11

      Josiah Zayner

    • @WTFMannyxFTW
      @WTFMannyxFTW 7 ปีที่แล้ว +2

      DMToad Its in the Video?

    • @iIO_OIi
      @iIO_OIi 7 ปีที่แล้ว

      Rollo Larson, it's the game Markus Person made before Minecraft, it allows you to watch videos and comment when you walk up to a terminal in the game.

    • @freedomforall2924
      @freedomforall2924 7 ปีที่แล้ว +1

      Rollo Larson ..it's found on TH-cam. Go to TH-cam and type www.TH-cam...then search TH-cam..click like and subscribe, then comment on TH-cam.

  • @matts.6234
    @matts.6234 7 ปีที่แล้ว +2

    I've taken some higher level biology classes and have been thinking about this stuff since I heard about CRISPR.
    It's been my dream to have access to this stuff, and this guy is making it accessible for anyone.
    This is going to be an amazing time for medical advancements due to his innovation.

  • @RockHoward
    @RockHoward 8 ปีที่แล้ว +5

    Zayner has been on a number of podcasts and they are all worth listening to.

  • @ThroughOurLensPodcast
    @ThroughOurLensPodcast 7 ปีที่แล้ว +48

    How can I subscribe to this guy

  • @umbrah
    @umbrah 8 ปีที่แล้ว +4

    I have witnessed and experienced paperwork politics,
    It can be overwhelmingly counter-productive.
    Open-source the world, and let the willing build.

  • @Lima547
    @Lima547 3 ปีที่แล้ว +1

    He is super right! I did my PhD in the UK and for 1 day experiment in the lab I had sometimes 1 full day of paperwork to be completed. Waste of time and money and we wonder why we don’t have a cure for cancer and other major diseases yet.

  • @mrman949
    @mrman949 5 ปีที่แล้ว +1

    I noticed myself saying: “thats dangerous” or “I don’t think it works that way”
    And then I realized, the institutions have closed my mind to possibilities. Rock on biohackers

  • @ranevc
    @ranevc 7 ปีที่แล้ว +14

    "Eating shit" is already a common therapy for some GE conditions.

    • @realitycheck3400
      @realitycheck3400 7 ปีที่แล้ว

      yourtv
      Yep, this "scientist" thinks HE's the shit.
      But in reality, this is shit. 💩

  • @tuxedo214
    @tuxedo214 7 ปีที่แล้ว +50

    Isn't it a little contradictory to talk about how people are gonna "blow our minds" with this newfound potential while at the same time saying that we shouldn't even talk about how it could be used in a malicious way because it's "not possible"?
    We'll go extinct from lack of wisdom long before we go extinct from disease or what have you. Regulations aren't perfect and the practice is young, let's do it right not quick and sloppy
    Also, keep in mind... this guy is making money off of every box he sells. It's only fair to question if what he says is genuine or motivated by capitalization on a fresh industry (ie: playing down the magnitude of the situation). Just be skeptical, it's good.. for science!

    • @andreasstuermer8101
      @andreasstuermer8101 7 ปีที่แล้ว +1

      Connor Scepticism is ok, but why don't you order a box and see how it works? Onle people afriad of it have no clue what this technology is

    • @tuxedo214
      @tuxedo214 7 ปีที่แล้ว +10

      Andreas Stuermer
      I know what CRISPR is I've been following it for years and come summer I'll be using it for research purposes.
      My hesitation isn't from a lack of knowing, it's FROM knowing how powerful this practice is and will eventually be. If you actually have the insight you claim, on this you would probably agree. But what I'm really concerned with is how this will be used out of the light of the public eye.
      No one's making these rules to hinder scientific progress, that's ridiculous. They're to keep us in check as we work towards the direction that we, as a community, agree won't either cause a biological disaster (intentionally or otherwise) or REALY disturb the public and cause policy makers to snuff this out before it even gets a chance to do us any good.

    • @AndersLindstedt
      @AndersLindstedt 7 ปีที่แล้ว

      Right? Over 99% of the comments are clearly from non-scientists. Very frustrating to read through these comments

    • @Aaron565
      @Aaron565 6 ปีที่แล้ว +3

      You idiot, a fifteen year old with an old dell desktop can permanently disable our national energy infrastructure in a matter of months and here you are thinking someone is going to from the ground up design a unique internationally controlled WMD bioweapon.
      To make something dangerous it takes a team and resources, that includes examples of other bioweapons. Anyone into that already has the gear.
      This is a hobbyist kit.

  • @MrJonsound
    @MrJonsound 7 ปีที่แล้ว +170

    playing with pot genes with my kit, hope to increase THC production with it

    • @ronpaulrevered
      @ronpaulrevered 7 ปีที่แล้ว +34

      I knew you were out there. Are you seriously doing this? Are you editing for speed, yield, terps, plant structure, calyx structure?

    • @Indra.artist
      @Indra.artist 7 ปีที่แล้ว +1

      trying it why not?

    • @doppelhelixes
      @doppelhelixes 7 ปีที่แล้ว +18

      my minds eye you are an idiot if you try that, if you transplant those genes, put them in other plants! the enzymes you need are known - you could let every plant produce THC or any other protein out of Weed, or just put those genes into yest and make a nice bear or bread

    • @Indra.artist
      @Indra.artist 7 ปีที่แล้ว +3

      asswipe

    • @TheAnantaSesa
      @TheAnantaSesa 7 ปีที่แล้ว +25

      maybe you can make a legal plant that produces THC. or make a strain of cannibus that is technically a new species and so not yet banned.

  • @BruceThomson
    @BruceThomson 7 ปีที่แล้ว +1

    Excellent video, thanks. I might buy the kit if I learn more about what it can do, the amount of complexity, time, etc.. Bruce Thomson in New Zealand.

  • @chocomalk
    @chocomalk 8 ปีที่แล้ว +10

    Cool guy.
    Bringing back the chemistry set in a big way lol

  • @mr19zee
    @mr19zee 7 ปีที่แล้ว +3

    the light responding protein could turn into a bio-computer processor or something similar

  • @Brad-lt6mr
    @Brad-lt6mr 7 ปีที่แล้ว

    Hands down the best thing I've watched in a long while. Does he have a channel?

  • @zebrom7994
    @zebrom7994 7 ปีที่แล้ว +1

    I don't think people realize most things we can do with crispr is doable already. The whole biohacking thing. But crispr makes it cheaper and quicker.

  • @tasteslikeawesome
    @tasteslikeawesome 7 ปีที่แล้ว +20

    yeast for LSD!

  • @darkbluemt
    @darkbluemt 7 ปีที่แล้ว +5

    This will be how man/bear/pig is created. Half man, half bear, half pig 🐷.

    • @bobgnarly1312
      @bobgnarly1312 7 ปีที่แล้ว +1

      darkbluemt two halfs make a whole

  • @sarahblossomware3753
    @sarahblossomware3753 7 ปีที่แล้ว +1

    Love this! I have a home lab complete with centrifuge, PCR machine, chemicals, beakers, etc. I guess I'm a biohacker? Cool, Josiah Zayner.

  • @dylangallagher1884
    @dylangallagher1884 8 ปีที่แล้ว

    this is crazy great. I am really interested and related to the products you are sharing. I am curious to look into the uses of your technology to look at soil microbes

  • @effies1959
    @effies1959 8 ปีที่แล้ว +62

    The cancer business will assonate him just like big oil killed off every other technology. I wish him the very best as he is the future

    • @doppelhelixes
      @doppelhelixes 7 ปีที่แล้ว

      Max Stephens unless you want to insert protooncogene out of other species, you would need to sequence your cancer genom and your own genom for finding the right rna to apply and fighting the cancer and you would need a 100% success rate, because one surviving cell is enough - and if you just insert protooncogene out of other species that became imune to cancer, good luck, nobody knows if that would heal you, kill you or don't do anything at all

    • @lakebass789
      @lakebass789 7 ปีที่แล้ว

      Tiefsee I feel a lab rat would be best to test this on first...

    • @tealeaflist
      @tealeaflist 7 ปีที่แล้ว +4

      Too Many of Us to assassinate.

    • @jerrywhidby5259
      @jerrywhidby5259 7 ปีที่แล้ว +4

      And nobody is going to talk about the elephant in the room. Well then I'm off to play Asson's Creed. LOL

    • @alexsiemers7898
      @alexsiemers7898 7 ปีที่แล้ว +1

      The Information Age makes that impossible to get away with...

  • @aeronomer8389
    @aeronomer8389 8 ปีที่แล้ว +111

    "Let's give people knowledge and let'em change the world." That's exactly why I consider myself a libertarian.

    • @Luka1180
      @Luka1180 7 ปีที่แล้ว +5

      Exactly. Give knowledge. As a centre-left person, or perhaps centrist, I believe in freedom and equality for everyone, but I also believe that you SHOULD have some knowledge on what you're doing with these kinds of things. But once you have that, I'd say do anything you want! Whether this knowledge should be gained through taking a PhD or other kind of doctorate, or just studying without necessarily going to institutions, I'm not sure about. Not just because it is safer; it is actually a lot more satisfying to work with these sort of things when you really know how they work.
      I do believe that the projects you work on during your education should be more unregulated in regard to what kind of things or products you want to study or develop. Like he said, there are too many regulations on that. People who feel like you should work on this, and not that, or just not work at all. Many universities do advocate for this kind of freedom, which is called 'academic freedom', but not there are too many who are too strict on it.

    • @petrabanjarnahor229
      @petrabanjarnahor229 7 ปีที่แล้ว +1

      Lukas Sprehn genetic engineering is going to destroy humanity at some point. Much like atomic bomb or something like that.

    • @arsenelupin5424
      @arsenelupin5424 7 ปีที่แล้ว +3

      Petra Marbun but it could also save it and/or prevent those other things oh poisonous virus get the virus run some tests until bacteria survives crispr boom cure etc.

    • @thehurts9216
      @thehurts9216 7 ปีที่แล้ว +2

      Gtfo with your politics. They have no place with science. Do you think all of mankind scientific breakthroughs and accomplishments happened because before starting an experiment people creates laws and rules to govern said experiment? Who cares about libs, left and rights. First off it matters not in science, and second, the party system is the worst thing for politics. It's exactly that kind of division that hurts the people

    • @rammy3767
      @rammy3767 7 ปีที่แล้ว +4

      Aero Nomer this was the dumbest, most off topic statement I've heard today

  • @upsty6499
    @upsty6499 5 ปีที่แล้ว +1

    This is amazing, I wish you all the success in the world. I'm interested in this technology and I believe you guys are doing humankind a service.

  • @anomalydheryn9360
    @anomalydheryn9360 7 ปีที่แล้ว

    awesome job reason TV.. that's really are important news to me.. can you gave the link on the description on where we can buy it.. thank you..

  • @tombumk7443
    @tombumk7443 8 ปีที่แล้ว +5

    Must say, he proves that you just can't judge a book by its cover. At first I saw the piercings and I was like, what's with this loser? Then I listened to him, and I now feel kinda small.

    • @couchgrouches7667
      @couchgrouches7667 6 ปีที่แล้ว

      Tom Bumk Reminds me of that one biker who trains cats

    • @danielmcbrearty5063
      @danielmcbrearty5063 6 ปีที่แล้ว

      still seems like a wacko looser, dudes making oats light up in his garage while eating his mates shit.

  • @SuperFinGuy
    @SuperFinGuy 8 ปีที่แล้ว +4

    Great video Reason. He should team up with Liz Parrish to bring up indefinite life extension.

  • @taurusvida4343
    @taurusvida4343 5 ปีที่แล้ว +1

    Eres admirable y no dejes que nadie te detenga. Siento que el mundo tiene demasiado dolor y si puedes ayudar a aliviar ese dolor, millones de familias serían felices. You are amazing ❤️

  • @jewelleryaddict
    @jewelleryaddict 8 ปีที่แล้ว

    like your way of thinking. am not in your class in terms of education on science but even I can see this idea of yours to spread knowledge and ability to the masses might harvest some wonderful new possibilities that may without you have taken generations to unfold given the "authorities" reign over sciences advances. carry on!

  • @huckaf
    @huckaf 8 ปีที่แล้ว +243

    This dude knows and has experienced the real deal. He is not a comformist sheep who mindlessly believes in all institutions without even having worked there.

    • @KevinP32270
      @KevinP32270 7 ปีที่แล้ว +2

      AGREED.

    • @diamondmetal3062
      @diamondmetal3062 7 ปีที่แล้ว +9

      Fer Contreras It's not really that fascinating. I got the thing and I understand how CRISPR works. All this is doing is spreading awareness of it. While CRISPR is revolutionary in every sense of the term. All this kit allows you to do is to modify bacteria so that they glow or don't grow in a petri dish

    • @fahimhuq2768
      @fahimhuq2768 7 ปีที่แล้ว +13

      Fer Contreras you're worse than those sheep.

    • @Fuar11
      @Fuar11 7 ปีที่แล้ว +10

      bisquitnspanky The irony here is laughable.

    • @vegetablescankill
      @vegetablescankill 7 ปีที่แล้ว +11

      Fer Contreras goddammit you fucking 'WOKE' nerds are even bigger sheep than normal people

  • @charlesmanning3454
    @charlesmanning3454 7 ปีที่แล้ว +8

    5:20 not something that should be thought about? Really? This guy has all wisdom of one his beer yeasts.
    Yes institution have revue boards because people were suffering due to unethical research. IRBs are big awful committees but the alternative is not necessarily better.
    What if people start getting cured? What if people start getting sick?

    • @Sweetenv77
      @Sweetenv77 5 ปีที่แล้ว

      Amen to tht !

  • @redstoneprojectrules
    @redstoneprojectrules 7 ปีที่แล้ว

    Do we also have to pay the $10.000 CRISPER-CAS license when we use this kit, or has this been taken care of?

  • @spiceaholic420
    @spiceaholic420 7 ปีที่แล้ว +1

    "And this is when I figured out: 'honest work is for suckers, government work doesn't make sense.' There saved you 5 min

  • @codyalexandervaldez8449
    @codyalexandervaldez8449 7 ปีที่แล้ว +8

    A major catalyst to contributing to the future, amazing person good for you buddy.

  • @VegasLoungeAct
    @VegasLoungeAct 8 ปีที่แล้ว +5

    What exactly can you do with the kit he sells?

    • @empresslithia
      @empresslithia 8 ปีที่แล้ว +6

      From what I understand, he only supplies the tools. What you do is up to you. It's possible to create a new super plant for example, or to make glow in the dark mice... I'm guessing you need to supply the RNA yourself.

    • @einstin2
      @einstin2 8 ปีที่แล้ว +11

      CRISPER CAS9 uses the cell's own machinery to edit the genetic code of that cell (and only those cells that are treated our descended from cells that were treated). You can use this to add any gene from one plant or animal to another. You could use this to make plants phosphorescent, make beer yeast that produces vanillin, or with some legislative barriers removed you can replace genes that cause Huntington's with healthy versions. You could also use this technology to make bacterial meningitis immune to current therapies, or a bacteria that targets people with sickle cell anemia, or possibly (though I'm not sure) create a nasty virus by first having the target virus carrier infect a bacteria, then editing the viral DNA while the bacteria is suspended, then having the bacteria produce the virus DNA that has now been edited to do whatever you want it to do.
      I'm a libertarian so I'm against government regulation of this, but I'd be a fool to not admit that I see the possible danger.

    • @RUNCOOKIE48
      @RUNCOOKIE48 7 ปีที่แล้ว +2

      You can only make bacteria resistant to an antibiotic, and then grow the bacteria on media that has the antibiotic. You cannot do anything else with just the materials he gives you

    • @andreasstuermer8101
      @andreasstuermer8101 7 ปีที่แล้ว +9

      Adam Billman You make designer viruses sound like a walk in the park. Viruses have evolved over millions of years. If you change anything - sometimes just one single amino acid, the immune system starts recognising it better and you wasted 10000s of euros and a few years of work

    • @einstin2
      @einstin2 7 ปีที่แล้ว +2

      Andreas Stuermer well everything sounds like a walk in the park when viewed from abstraction. You will note that I didn't mention the expensive supercomputers that deal with protein folding simulations to ensure the virus protein shell functions properly, or the difficulty of producing entirely synthetic DNA, or the years of testing and clinical trials that would be required for therapeutic use. There is a difference between possible and easy.

  • @LaSanya2001
    @LaSanya2001 7 ปีที่แล้ว +1

    I'm very sure through this man we could make plants that we already use, make even more useful i.e. remove the toxin Solanin from the fruit of Potatoes and remove both Solanin and Tomatin from the Tomato so we can use the entire Tomato plant. Through Genetic Modification, we could also save endangered plants like all the Sequoia trees by increasing their low germination rate that is pretty low or introduces genes that allow the trees to build anti-freezing chemicals.

  • @chrisw1462
    @chrisw1462 4 ปีที่แล้ว +1

    Mother of Storms - John Barnes (book) - A distopian future scifi epic that looks at gene modification from both sides - light and dark, legal and illegal - and then takes it to a whole new level entirely. It'll really make you think.

  • @stickynote5674
    @stickynote5674 7 ปีที่แล้ว +4

    This guy is amazing.

  • @darklight6921
    @darklight6921 8 ปีที่แล้ว +3

    love this guy.

  • @filipplimitowski6430
    @filipplimitowski6430 6 ปีที่แล้ว

    Does this method modifies every cells’ dna or of just one cell?

  • @waslineilezer8733
    @waslineilezer8733 5 ปีที่แล้ว

    Great stuff bro! I like the way you compare this early stage of gene editing as the primitive stages of innovated technologies that we as humans use pretty much in all of our daily lives. My question is, wasn’t mircobita implants introduced before crispr?

  • @jisookim6904
    @jisookim6904 7 ปีที่แล้ว +4

    Did anybody try this? I am curious how it's supposed to work. As far as I know (only began as undergraduate) you need to know the genome of whatever you're editing, okay, so maybe you find that in a data base. Then you need to make a template for the part of the genome you want to add. I found out there's computer programs that you can use and that you can then order these templates by mail. Then the problems really begin, you now got your buffer, templates, the genome you want to edit and everything else necessary. You need a centrifuge to properly mix it. You need a special oven that keeps the temperature exactly right for the enzyme. Even if you manage all that without the proper machines and you can do the next steps at some point you need to know whether it worked and for that you need a sequencer. So you'd have to send samples of what you made to an actual laboratory to make sure. This is absolute bogus if you ask me. Every time you want to do a single experiment it would cost you a hundred dollars just for all the mail. Plus the machines you need and the computer programs and the books (because you sure as hell aren't smart and skilled enough to do it without all of that). Crispr/Cas9 is easy, for people having the right equipment and experience in molecular biology. That's also why the dude isn't worried that anybody could produce something dangerous (which is entirely possible if scientists would put their mind to it). It's just not going to happen with a few chemicals and pipettes you ordered online, the idea of democracy in science is nice but genome editing isn't the best place to start, it goes way over the head of the general public and it certainly will require a few thousand dollars investment if you seriously want to get somewhere. In my opinion this guy is more likely running a scam than seriously trying to help people invent new stuff. If he was serious about that he'd be explaining how exactly Crispr/Cas9 works and how it can be done in your own basement.

    • @EMed9423
      @EMed9423 6 ปีที่แล้ว

      Jisoo Kim Are you still interested in the process of CRISPR and Cas9?

  • @MartinusHoevenaar
    @MartinusHoevenaar 7 ปีที่แล้ว +5

    The new Lego. :-)

  • @LoveBuhay
    @LoveBuhay 7 ปีที่แล้ว +1

    I love how freedom of openness to the possibility to the possible

  • @user-qr5fg1os8e
    @user-qr5fg1os8e 5 ปีที่แล้ว

    Hi. This is the sbs broadcasting station in Korea.
    We are preparing a documentary on health early next year.
    I'm looking for various images of biohackers.
    It was decided that this video was discovered on TH-cam.
    It's a very good video.
    "Do you mind if I let you know where you came from and broadcast it on our TV? I leave adress.
    Please give me a positive reply.
    Thank you very much.

  • @RecklawTheAmazing
    @RecklawTheAmazing 7 ปีที่แล้ว +7

    Not sure if I approve of this in principal, but it's really fucking cool in practice.

  • @scottoswald7535
    @scottoswald7535 7 ปีที่แล้ว +16

    Wow, well done. I can't wait to see what amateur scientists come up with.

  • @Liberty4Ever
    @Liberty4Ever 8 ปีที่แล้ว

    I'm Doctor Science (a self conferred title) and this scares the crap out of me! Interesting interview, though.
    Homer Simpson inadvertently crossed the tomato with tobacco to create the tomacco plant, which produced highly addictive nicotine laced tomatoes. I want to make strawberries that contain caffeine. With $140 CRISPER kits, you can bet half our biosphere will be producing THC within 50 years. As Hunter Thompson observed, when the going gets weird, the weird turn pro.

  • @bentnickel7487
    @bentnickel7487 5 ปีที่แล้ว

    Heard Zayner on the Coast to Coast radio program, learned just enough to know he's on to something. Thanks Josiah.

  • @sabereaseera1384
    @sabereaseera1384 7 ปีที่แล้ว +5

    I wouldn't trust anyone that looks like that

    • @ssach7
      @ssach7 7 ปีที่แล้ว +4

      I bet you'd trust a random guy in a suit then?

    • @sabereaseera1384
      @sabereaseera1384 7 ปีที่แล้ว +1

      E S probably

  • @corlfranco9371
    @corlfranco9371 7 ปีที่แล้ว +9

    year 2050: the biosphere is broken and mutant spores invaded every plant and living thing, making it grow strings a fibrous material in insanelly massive ammounts from every sqaure inch of surface

    • @Jayheid98
      @Jayheid98 7 ปีที่แล้ว +3

      Corl Franco Halo??

    • @illDefine1
      @illDefine1 5 ปีที่แล้ว

      Until we splice em.

    • @mynameisnobody5838
      @mynameisnobody5838 5 ปีที่แล้ว

      Corl Franco Uh year 20..... now what do you think is happening right now what do you think morgellons is? The government is way ahead of you on that.

  • @MrCTruck
    @MrCTruck 7 ปีที่แล้ว

    What sort of antibiotics did you use for clearing your gut?

  • @joesniffer9815
    @joesniffer9815 7 ปีที่แล้ว +1

    Great video :) Too many scientific developments are suppressed simply because the discovery was made by the wrong person (not being in academia, not having PhD, et cetera). Props to this man. Science must be the Number One priority of the human species. Stop the wars and focus on education!

  • @BenWillock
    @BenWillock 8 ปีที่แล้ว +14

    $140 CRISPR kits? That seems like a good way to make bio-terrorism a reality.

    • @jowge6759
      @jowge6759 8 ปีที่แล้ว +4

      Did you even watch the video?

    • @BenWillock
      @BenWillock 8 ปีที่แล้ว +12

      BadlyDrawnFrog Yes, the fact that he answered the question by dismissing it out of hand doesn't mean its no longer a valid point.

    • @jowge6759
      @jowge6759 8 ปีที่แล้ว +6

      *****
      He didn't dismiss it out of hand. He clearly said that the kit doesn't contain anything that can be used to cause harm or put a weapon in the hands of the wrong people.

    • @TheAnantaSesa
      @TheAnantaSesa 7 ปีที่แล้ว +2

      can that statement be verified? there are lots of pro-gmo activists that dismiss the threats that will outlive them. it's not courage when it's stupid recklessness. some people just don't care as much as others so naturally the more dissatisfied will be more eager to take their chances with untested tech. +BadlyDrawnFrog

    • @mackenziebarefoot1913
      @mackenziebarefoot1913 7 ปีที่แล้ว +3

      I mean pressure cookers arnt supposed to do harm but look at why when you buy one, you're now on a list. you can turn anything to a weapon

  • @danodbdb
    @danodbdb 7 ปีที่แล้ว +59

    Unfortunately crisper will be used for evil.

    • @andreasstuermer8101
      @andreasstuermer8101 7 ปีที่แล้ว +3

      danodbdb How so?

    • @andreasstuermer8101
      @andreasstuermer8101 7 ปีที่แล้ว

      Yupaki Eidemo How would you add new proteins to a virus without making it visible to the immune system? Nature has billions of years head-start over us

    • @andreasstuermer8101
      @andreasstuermer8101 7 ปีที่แล้ว +1

      Yupaki Eidemo People may try but it's extremely hard. Even 20 years from now. Trust a science guy on this. Also there will be good biohackers writing biological anti-virus software/vaccines

    • @underglow59
      @underglow59 7 ปีที่แล้ว +2

      the way you make it sounds is like you would be playing a game of who can out code who. 140$ and anyone and everyone could bio engineer a super bug . seems a bit irresponsible .

    • @mrspidey80
      @mrspidey80 7 ปีที่แล้ว +8

      It's a tool like any other. Hammers can be used for evil too.

  • @colin7225
    @colin7225 7 ปีที่แล้ว

    Iv always thought it would be cool to have six arms, like goro from mortal combat. I could achieve so much more, is this possible with your kit?

  • @rahulpaul2976
    @rahulpaul2976 5 ปีที่แล้ว

    Is it possible to change skin color by using crispr cas9 treatment?

  • @LNasterio
    @LNasterio 7 ปีที่แล้ว +6

    I'm not so sure largely spread unregulated GMO product is a good idea...
    but I'm not opposing what he is doing either.

    • @TheBenrollo
      @TheBenrollo 7 ปีที่แล้ว +1

      Asterio why?

    • @andrep4805
      @andrep4805 7 ปีที่แล้ว

      TheBenrollo chemicals can degrade, if released in the environment. Organisms can survive and breed, if released. A realistic problem could be like so: an engineered bacteria that makes soil richer causes reduced fertility in another organism(say it out competes another bacteria). Something simple that could be a real problem.

    • @Aaron565
      @Aaron565 6 ปีที่แล้ว +1

      No, you'll not create something so successful that a singular instance of it takes over the biosphere.

  • @bilbo_gamers6417
    @bilbo_gamers6417 7 ปีที่แล้ว +57

    And then Christianity comes along...

    • @bckey1440
      @bckey1440 7 ปีที่แล้ว +5

      The Nazis were occultists

    • @undiecover3939
      @undiecover3939 7 ปีที่แล้ว

      Philemon6 no they werent

    • @WaterspoutsOfTheDeep
      @WaterspoutsOfTheDeep 7 ปีที่แล้ว +6

      Christianity brought about modern science and universities. It is the backbone of the rise of western society.

    • @somemaycallthisjunkmeicall133
      @somemaycallthisjunkmeicall133 7 ปีที่แล้ว

      bisquitnspanky
      Christianity embraces jews

    • @Hakken1
      @Hakken1 7 ปีที่แล้ว +5

      Philemon6 Look out! We have someone here who's actually read their history! Yes. The Nazi were occultists.

  • @tymesho
    @tymesho 8 ปีที่แล้ว +1

    this is happening in a very small warehouse in Ann Arbor Mi. the possible result will be the first "living" bio screen for hand helds. super tough, but if it does break, the material is "grown" back. literally just a few years, FEW! away.

    • @MilwaukeeF40C
      @MilwaukeeF40C 8 ปีที่แล้ว +2

      Who's going to wait a few years for the screen to heal?

  • @bkingk8
    @bkingk8 7 ปีที่แล้ว

    I worked for the Australian government for 8 years, my last 4 years was spent sitting on my ass doing nothing for 90k + a year.
    Thank fuck i took a redundancy and got back into the private industry.

  • @SevastianNandez
    @SevastianNandez 7 ปีที่แล้ว

    Can you modify my genes to lower my calve insertions and make them more prone to muscle stimulation

  • @adamdye88
    @adamdye88 7 ปีที่แล้ว

    Is possible to use to make bees stronger & less affected by harmful chemicals? If so where can I get this?

  • @inappropriatecontent2589
    @inappropriatecontent2589 6 ปีที่แล้ว

    Entering college this year with a major in biotechnology, sooooo excited!

  • @justincarnes1553
    @justincarnes1553 7 ปีที่แล้ว +1

    This guy's hope and trust in humanity is so inspiring

  • @nicklandreth2527
    @nicklandreth2527 4 ปีที่แล้ว +1

    Could we use open source bio licenses to prevent Monsanto from owning everything couldn't we?

  • @amosbackstrom5366
    @amosbackstrom5366 7 ปีที่แล้ว +2

    I can hardly believe this. This is absolutely amazing.

  • @ivan6139
    @ivan6139 5 ปีที่แล้ว

    If you are already dying, what would you do? Will you wait till it come for you even if you have a way to get cured or will you go for it? No one wants to die.

  • @tsoha85
    @tsoha85 7 ปีที่แล้ว

    I love the topic. I liked the video.
    Just one thing though. Devices that have access to a culture/species collective knowledge is a common and ancient theme. Being "portable" is even a super old idea even though slightly less common idea also. The idea and/or desire for such a thing has always been around. What I think he meant to imply was that, "nobody accurately predicted" that it would be the phone to fill the niche. Science fiction, fantasy, religion, and even folklore all have this very concept somewhere in them.
    Overall though, I'd give it a 8/10. Only because I feel like there is important content missing. I can only presume to guess that either more questions were asked and then just edited out, or, you didn't even ask some of the best questions. This feels like a teaser for a really good interview.

  • @Kenshiroit
    @Kenshiroit 5 ปีที่แล้ว

    Is it possible to stimulate activate or transplant genes in a plant to grow a tree out of it?

  • @themarinatedgentleman9563
    @themarinatedgentleman9563 7 ปีที่แล้ว

    I want one!!! I specifically want to work on candida overgrowth, and autoimmune diesease.

  • @tebogomonkwe3026
    @tebogomonkwe3026 7 ปีที่แล้ว

    where can we order the crispr toolkit

  • @geo3219
    @geo3219 7 ปีที่แล้ว

    Josiah Zayner, you the man dawg. Go crowd sourcing with chemistry and research. This sounds like a capital idea old boy. As the arduino took off to interesting places, this will no doubt make some fun do it yourself builds. Who knows where the first thousand kits ship to. ? ? Shagadelic baby ! ! !

  • @oljimeagle
    @oljimeagle 7 ปีที่แล้ว +1

    "Ma Im quitting NASA and Im gonna do science in the basement.."

  • @HoneyViVi
    @HoneyViVi 7 ปีที่แล้ว

    Where can I get this kit?

  • @jaredgarden2455
    @jaredgarden2455 7 ปีที่แล้ว

    I have an amateur chemistry lab with a decent amount of equipment including 3 neck RB flask, condensers, beakers and Erlenmeyer flasks, claisen adapters and a few other bits and pieces.
    Haven't discovered anything new but i work away at my projects every weekend, trying to synthesize interesting compounds.
    Unfortunately though i don't know anybody else that does this sort of thing except the other chem nerds on the internet.
    I talked to the cops about it and they said im the first amateur chemist they have come across for decades, atleast in my area.
    :(

  • @astspace6708
    @astspace6708 6 ปีที่แล้ว

    I am hosting an open community lab with a orientation on biology. We have used Aminolab's product to teach synthetic biology to the public. I wonder if we can get some samples and instruction from your lab to teach CRISPR techniques? We can get back to you about the feedbacks we might received from our participants

  • @michaelg1061
    @michaelg1061 7 ปีที่แล้ว

    The original idea of a device using bioluminescent genes as a part of it could potentially be a step forward toward organic / biomechanical circuitry which actually does have merit as computers able to grow replacement parts simply thru cell division could have relevant applications to space travel among other things

  • @harmhoeks5996
    @harmhoeks5996 7 ปีที่แล้ว +1

    Amazing. Both on product & attitude

  • @carltonsorrells7609
    @carltonsorrells7609 7 ปีที่แล้ว

    I've only watched 35 seconds but I enjoy every detail so far. Why? Just because I support the idea, and advancement and evolution of the human race.

  • @swalexander6218
    @swalexander6218 4 ปีที่แล้ว +1

    We need independent progressive scientists who are willing to find crispr9 solutions for psoriasis. Example: why psoriasis reacts aggressive after eating tomatoes or other nightshades.

  • @alexanderx33
    @alexanderx33 6 ปีที่แล้ว

    Haven't watched the video, just came here to say seeing this title on reason tv seems like the prequal to the bioshock series.

  • @scottcosentino5239
    @scottcosentino5239 7 ปีที่แล้ว

    how do i get this kit? i want it

  • @ToiletBowl
    @ToiletBowl 7 ปีที่แล้ว

    I've read things of this bio hacking when I was in middle school and you fast forward 10 years to now and this has simply became more advanced. I've read how you can alter the genetics of a child to the specifications of your choosing. Anything from height to intellect. I can see this being useful but it's like fire playing with fire.

  • @GodWorksOut
    @GodWorksOut 7 ปีที่แล้ว

    Institutions see innovation as risk and that's probably why it's more focused on mass producing and utilizing already tried and true methods.
    Gene manipulation is so fascinating... we'll be taking control of our own evolution!

  • @rahulpaul2976
    @rahulpaul2976 3 ปีที่แล้ว

    it is possible to change skin color by using gene therapy /crspr cas9??

  • @rusticrick999
    @rusticrick999 5 ปีที่แล้ว

    I haven't bought one of these kits but I have done CRISPR, cloning, PCR you name it. DNA oligomers have to be designed and ordered from a biotech company, plasmids have to be purchased. Even if someone is knowledgeable enough to pick out the right genes and engineer the oligomers correctly, no biotech company is going to sell DNA oligomers or plasmids to the general public since they don't want to deal with individuals, only reputable institutions with accounting departments. I see a huge disconnect here so someone enlighten me how this is going to fly.

  • @Search4truth488
    @Search4truth488 7 ปีที่แล้ว

    This is one area where I happen to completely agree with the libertarian stance. One thing I've seen first hand is psychiatric medication, where there are drugs which are both less harmful and more effective, but doctors advise people not to take them because they're going through unnecessarily long clinical trials.

  • @acidfroggy1194
    @acidfroggy1194 7 ปีที่แล้ว

    When you think about it America's greatest inventors started out this way. They were not the product of central planning or academic grants. They tinkered, invented, and Society reaped the benefits.