Longevity: can ageing be reversed?

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  • เผยแพร่เมื่อ 12 พ.ค. 2024
  • Ageing has always been inevitable but fasting, epigenetic reprogramming and parabiosis are just some of the scientific techniques that seem to help people stay young. Might the Peter Pan dream become real?
    00:00 - Can science turn back the clock?
    01:01 - Centenarians
    02:51 - What is ageing?
    04:51 - Dietary restriction
    06:00 - Roundworms
    07:55 - Epigenetics
    09:43 - Blood and guts
    11:40 - Senolytics
    12:38 - Metformin
    13:51 - Anti-ageing treatments are coming
    Sign up to The Economist’s daily newsletter: econ.st/3QAawvI
    Read the Technology Quarterly on longevity: econ.st/462fqto
    Christian Californians may have a solution to America’s obesity: econ.st/3EC4GG9
    How to eat to 100: econ.st/3EwQTAq
    Who wants to live forever? Quite a lot of people: econ.st/3LjHBMh
    Is longevity more than a billionaire’s pipe-dream? Listen to our science and technology podcast Babbage to find out more: econ.st/3PzSbBl
    A $3bn bet on finding the fountain of youth: econ.st/3EzGZyb

ความคิดเห็น • 549

  • @healthquest365
    @healthquest365 7 หลายเดือนก่อน +161

    The research into slowing down or even halting the aging process is indeed a fascinating and rapidly evolving field! Thanks for a great video.

    • @ashdang23
      @ashdang23 7 หลายเดือนก่อน +4

      It is entirely possible to happen by 2050. if things get better and go according to plan we could be living in Disney land by 2050.
      (speculation)

    • @Dr_Oleg_Kulikov
      @Dr_Oleg_Kulikov 5 หลายเดือนก่อน +2

      A singularity point is near. Do you think AI and governments need people living longer?

    • @erikhonkys118
      @erikhonkys118 18 วันที่ผ่านมา

      @@Dr_Oleg_Kulikov actually yeah. If there will not be many people. There will be no diverse and even AI will go insane.

  • @ChuckStaley
    @ChuckStaley 7 หลายเดือนก่อน +143

    As I approach my 92nd birthday, I thought that I may want to get some longevity tips, so I started watching these different videos and realize how much information there is! When I'm asked how I got to be in my 90s without one serious illness or medication I give them my secret: Your belief makes it so!

    • @y.g.1313
      @y.g.1313 6 หลายเดือนก่อน +3

      Just to clarify: you stated that it is your consiencious belief, that is propelling your longevity without any disease at age of 92?

    • @ChuckStaley
      @ChuckStaley 6 หลายเดือนก่อน +2

      Yes. And my belief that I will live for many years ahead. I repeat to myself daily: I am a healthy, wealthy and wise young man... And so it is.
      I might add: I had every childhood disease, smoked 3 packs of cigs a day for 20 years, tried and used most every drug in the 70s, don't exercise much, and eat what I want. Two weeks ago I started skipping breakfast and I see weight and shape results. @@y.g.1313

    • @Christaraspap
      @Christaraspap 6 หลายเดือนก่อน +16

      Having a positive mindset is important but it's not enough. If you don't eat a balanced diet, don't exercise, don't sleep well and if you're smoking and drinking, no matter how happy you are, you will not live long.

    • @serenakoh136
      @serenakoh136 6 หลายเดือนก่อน +1

      @@y.g.1313*conscientious

    • @nicolatesla5786
      @nicolatesla5786 5 หลายเดือนก่อน +1

      The best way would be start your raw vegan diet when you're in your teens and 20s.

  • @andreigheorghe3135
    @andreigheorghe3135 7 หลายเดือนก่อน +46

    Go anti aging community!

  • @blink182bfsftw
    @blink182bfsftw 7 หลายเดือนก่อน +52

    That woman looks 60 😮 she's 98?!

    • @palestinabaddie
      @palestinabaddie 3 หลายเดือนก่อน

      yes

    • @Dan-uf2vh
      @Dan-uf2vh หลายเดือนก่อน

      nah, she looks 80

    • @splintcell22
      @splintcell22 หลายเดือนก่อน

      @@Dan-uf2vh nah, she looks 180

  • @SilverFan21k
    @SilverFan21k 7 หลายเดือนก่อน +45

    Thank you The Economist very much for this great video and all the recent articles on Longevity! ❤

  • @GiornoJovani
    @GiornoJovani 7 หลายเดือนก่อน +143

    0:13: 🧪 Scientists are researching ways to slow down or even stop the aging process, attracting significant investment.
    3:27: 🐢 Ageing can be changed, as shown by the example of Aldabra giant tortoises who hardly age at all.
    7:00: 🧬 Changing certain genes can slow down aging and increase lifespan in animals.
    10:27: 🧪 Parabiosis, the linking of blood circulations between animals, has shown potential for extending the lifespan of older animals.
    13:05: 💊 Certain drugs, such as metformin and rapamycin, have been shown to slow down aging and improve health in diabetics and non-diabetics.
    Recap by Tammy AI

    • @ambition112
      @ambition112 7 หลายเดือนก่อน +7

      Thanks for saving my time! amazing summary with lovely time stamps! where you get this Tammy AI?

    • @jdlk-ny5yo
      @jdlk-ny5yo 7 หลายเดือนก่อน +7

      You just made my life 15mins longer….now if only I had something to do with it

    • @rejiequimiguing3739
      @rejiequimiguing3739 7 หลายเดือนก่อน +1

      Now also glucosamine, alpha ketoglutarate, taurine, glycine, aspirin.

    • @taniamariadeoliveira2089
      @taniamariadeoliveira2089 7 หลายเดือนก่อน

      ❤👏👏👏👏👏

    • @glennprentice6051
      @glennprentice6051 7 หลายเดือนก่อน

      Can you please send me some references for Metfornin’s benefits as we age?

  • @isalutfi
    @isalutfi 7 หลายเดือนก่อน +12

    Thank you for sharing this insightful and helpful video.

  • @chaitassy
    @chaitassy 7 หลายเดือนก่อน +49

    ❤ I'm 68 but look like 50 I'm still working and productive! Thank for these information. It's encouraging me move forward in my future years!😊

    • @brunoheggli2888
      @brunoheggli2888 7 หลายเดือนก่อน +6

      The earlyer we die the better!I never heard dead people complaining about being dead!Its just about how we die,hopfully painfree and just sleep forever peacefull!We all arent that importend!

    • @Frostbiker
      @Frostbiker 7 หลายเดือนก่อน +1

      Bruno: kindly lead the way. We promise to follow you. Eventually.

    • @brunoheggli2888
      @brunoheggli2888 7 หลายเดือนก่อน

      @@Frostbiker Yes sure you sleep and never woke up again and you dont know when it happens!Maybe this night,maybe in 30 years whats the diffrence?We arent that importend,the world can live without us!

    • @brunoheggli2888
      @brunoheggli2888 7 หลายเดือนก่อน +1

      @@Frostbiker And all this"I am 68 but looks like 50 and i am still productif"who cares?You want an Oscar for that?You arent more worth then someone that is 50 looks 68 and is unproductif!Its crazy how people think that they are sooooo importend and so valueable for humanity that they think their mind should be preserved by uploading their crazy ego to a computer!

    • @bcase5328
      @bcase5328 7 หลายเดือนก่อน +2

      One thing which would need to be changed is employer age discrimination. They hide it, but it is very real and can start when the employee is in their 40s.

  • @evanmathias7490
    @evanmathias7490 7 หลายเดือนก่อน +10

    The process of cellular reprogramming, which involves the introduction of four transcription factors known as Yamanaka factors, can reverse the epigenetic and functional age of cells, restoring their pluripotency and rejuvenation. By using this technique, it may be feasible to generate autologous bone cells that are derived from one's own somatic cells, but have a younger biological age. These cells can then be used in conjunction with 3D printing technology, which can create customised and biocompatible bone scaffolds that match the shape, size, and structure of the desired bone tissue. By transplanting these 3D printed bones into the body, it may be possible to replace damaged or diseased bones with younger and healthier ones, as well as to stimulate the endogenous bone regeneration and repair mechanisms. This may also have systemic effects on the overall health and longevity of the individual, as the transplanted cells may secrete factors that can modulate the aging process of other tissues and organs .

  • @k.h.6991
    @k.h.6991 7 หลายเดือนก่อน +18

    As others here have noticed, you've completely ignored the diet and lifestyle things people can implement today. Perhaps because they don't require a startup? Look into Walter Longo's work on longevity. Oh wait, he does have a startup.

  • @Biohacker24
    @Biohacker24 7 หลายเดือนก่อน +2

    Amazing 🙌🏽

  • @mehmet.albyrk
    @mehmet.albyrk 3 หลายเดือนก่อน +1

    While watching I feel happy with all generous information given on this vivid topic thanks for your great work.

  • @karenmateo4969
    @karenmateo4969 4 หลายเดือนก่อน +4

    The research that the scientifics are doing is very interesting. I didn’t know about this, but I’m very surprised at the posibility of slowing down or even stopping the aging proccess. What caught my attention was that they are not only interested in aging, but also in a healthy aging and about the positive effects on our society.

  • @VivaLaVittoria
    @VivaLaVittoria 5 หลายเดือนก่อน +27

    One of the missing pieces of this discussion is that so many of the "age related diseases" are actually LIFESTYLE related diseases. The lifestyle one has lived for decades simply catches up with one the longer they've been around. Research already shows that lifestyle (physical activity, diet, social connections, smoking, etc) has a huge impact on morbidity and mortality on a population level.

    • @chickensalad3535
      @chickensalad3535 4 หลายเดือนก่อน +4

      The reason that it “catches” up with us though is typically because our body’s defenses have degraded to the point where they can’t fight certain issues off.

    • @DEBO5
      @DEBO5 3 หลายเดือนก่อน +3

      @@chickensalad3535yes but imagine it didn’t have to fight those unnecessary battles and could instead work in improving the immune system

  • @JL-vk1rs
    @JL-vk1rs 6 หลายเดือนก่อน +2

    very well done and interesting video!

  • @jonh9561
    @jonh9561 7 หลายเดือนก่อน +1

    Fascinating video.

  • @stephensharma4994
    @stephensharma4994 7 หลายเดือนก่อน +28

    YES!! science can slow down ageing ,,, the human body is all about its bio-chemistry , but unfortunately we have not reach that level of scientific advancement ,,,, may be some day we will!!

    • @roryblake7311
      @roryblake7311 7 หลายเดือนก่อน +1

      Patents are pending...

    • @Izakokomarixyz
      @Izakokomarixyz 6 หลายเดือนก่อน +6

      slowing age? i think we might actually reverse it. but perhaps there’s also a way to make aging slow down considerably as well.

    • @palestinabaddie
      @palestinabaddie 3 หลายเดือนก่อน +1

      @@Izakokomarixyz when will we permanently stay young

    • @luisfernando5998
      @luisfernando5998 3 หลายเดือนก่อน

      Hopefully ChatGPT will find a solution

    • @dill6827
      @dill6827 หลายเดือนก่อน +2

      One step at a time, hopefully someone in the future will be able to get there.

  • @user-yf9jn4ji1m
    @user-yf9jn4ji1m 2 หลายเดือนก่อน

    Amazing report, love it ❤

  • @ronnianabalos4627
    @ronnianabalos4627 6 หลายเดือนก่อน +3

    Definitely worth my time to watch❤😊❤

  • @thetype85
    @thetype85 7 หลายเดือนก่อน +18

    It is disappointing that they barely covered limited calorie intake.
    Intermittent fasting promotes autophagy.
    Autophagy is well known in the medical field to reduce inflammation and increase lifespan.
    It is literally a mode your body enters where it starts to recycle old damaged cells, One of the big advantages is it reduces the risk of cancer.

    • @cleitondecarvalho431
      @cleitondecarvalho431 5 หลายเดือนก่อน +2

      I never heard of it. Tell me more, is there tips of how to fast in a healthy way ?

    • @luisfernando5998
      @luisfernando5998 3 หลายเดือนก่อน

      @@cleitondecarvalho43123 hr fast 1 hr eating window u won’t age

    • @jimsimpson1006
      @jimsimpson1006 หลายเดือนก่อน

      But a recent study has cast doubt on it, linking it to a much higher risk of cardiovascular disease. I do hope it turns out to be wrong!

    • @mlachaise
      @mlachaise หลายเดือนก่อน +2

      @@jimsimpson1006That wasn’t a scientifically peer reviewed study. It was a presentation at a conference on a survey. Digging into the presentation, it’s shown to be full of very dubious statistical sampling and methods. It clearly looks like an attempt at gaining attention for the authors.

    • @mlachaise
      @mlachaise หลายเดือนก่อน

      @@cleitondecarvalho431Look up intermittent fasting on TH-cam. There’s been a lot of scientific evidence in animal models that it greatly extends the healthy period of one’s lifespan. It’s theorized that things work similarly in humans. It’s a big trend right now in the health and longevity community.

  • @Thaythichgiachanh262
    @Thaythichgiachanh262 4 หลายเดือนก่อน

    Thanks for all your great advice. I really enjoy watching your videos, they provide a lot of knowledge and are very helpful on a daily basis in choosing food when shopping, etc. Thank you ❤✨

  • @Quixote1818
    @Quixote1818 7 หลายเดือนก่อน +15

    You can clear senescent cells by fasting for 2 to 3 days one or twice a year. It's called autophagy or self eating. Prolonged fasting has many longevity benefits, including improving brain function.

  • @nmagnus9924
    @nmagnus9924 6 หลายเดือนก่อน +1

    What a wonderful video, thank you!

  • @davisoaresalves5179
    @davisoaresalves5179 7 หลายเดือนก่อน +1

    Loved Keynes quotation.

  • @santosnaosantos
    @santosnaosantos 7 หลายเดือนก่อน +5

    I have multiple sclerosis, I just want the healing to live well, I just want to be able to live.

  • @abdulrashidparacha5899
    @abdulrashidparacha5899 7 หลายเดือนก่อน +1

    Excellent 👌

  • @user-yv4gg7jb2f
    @user-yv4gg7jb2f 7 หลายเดือนก่อน

    nice topic and music btw

  • @mvrao29
    @mvrao29 6 หลายเดือนก่อน

    Excellent treatise on longevity.

  • @sub9ironman
    @sub9ironman 7 หลายเดือนก่อน +87

    If you want to cheat aging, you need to do physical activity every single day of your life without interruptions.

    • @roryblake7311
      @roryblake7311 7 หลายเดือนก่อน +6

      Daily walking is essential. Walking moves lymph (containing nutrition) from the gut to the lymph nodes. If nutrition stays in the gut it is consumed by parasitic bacteria in the microbiome.

    • @craigpardy6204
      @craigpardy6204 7 หลายเดือนก่อน +8

      How is this cheating?

    • @jimj2683
      @jimj2683 7 หลายเดือนก่อน +11

      Sure, but cancer, dementia or a heart attack is still going to get you before you are 100. Also, you will be weak and frail. What we need are radical new treatments: Gene therapy, stem cell therapy, epigenetics etc...

    • @davidstrong7854
      @davidstrong7854 7 หลายเดือนก่อน +6

      yes , but that is only one part of it. But activity is the cheapest and most available method.

    • @roryblake7311
      @roryblake7311 7 หลายเดือนก่อน +1

      @@davidstrong7854 Daily walking circulates Lymph better than other forms of activity.

  • @mikhailmamontov2155
    @mikhailmamontov2155 5 หลายเดือนก่อน +24

    I retired at 48, and for 10 years I work out, swim every day, eat right, sleep enough, avoiding all financial and family stresses. It simply does not work, I age every year, and I notice it. I am not afraid of aging and dying, I just monitor myself for fun because I do not need to work. Probably to prevent aging one has to use a lot of medications.

    • @h.h8766
      @h.h8766 5 หลายเดือนก่อน +3

      How were you allowed to retire at 48? That is very young.

    • @TouringTony
      @TouringTony 4 หลายเดือนก่อน +1

      Are you working your brain or just your body?
      Do you have a strong social network?
      Stopping work can be bad for your health. I semi retired 5 years ago and haven't felt like I'm ageing. I cycle regularly and keep my brain very active

    • @kenc8359
      @kenc8359 4 หลายเดือนก่อน

      Got a social circle? Any friends?

    • @palestinabaddie
      @palestinabaddie 3 หลายเดือนก่อน

      @@kenc8359 I don't :(

    • @Leon-th6nl
      @Leon-th6nl 3 หลายเดือนก่อน

      well yeah obviously, all the stuff you mentioned is the bare minimum you need to do to slow aging down

  • @estebanlegare
    @estebanlegare 7 หลายเดือนก่อน

    Fascinating

  • @Anil18834
    @Anil18834 7 หลายเดือนก่อน +1

    Brilliant

  • @nccccccccccccc
    @nccccccccccccc 7 หลายเดือนก่อน +2

    There's still one important purpose of mechanism of aging - novelties in culture,ideas,and systems(political or ideological)

  • @squamish4244
    @squamish4244 7 หลายเดือนก่อน +1

    Let's do this!

  • @thechayanbiswas
    @thechayanbiswas 7 หลายเดือนก่อน +2

    does this affect the kidneys?

  • @sakismpalatsias4106
    @sakismpalatsias4106 7 หลายเดือนก่อน +1

    Yes

  • @sofipanfer
    @sofipanfer 4 หลายเดือนก่อน

    The discussion about cellular rejuvenation and the role of genetic interventions offers a glimpse into the exciting possibilities. This video not only educates viewers on the science behind aging but also sparks contemplation about the ethical implications and societal impact of potentially extending human lifespans.

  • @swenic
    @swenic 7 หลายเดือนก่อน +11

    Biological ageing is the accumulation of cellular damage. Cellular repair is down-regulated when we are in "Fight-or-Flight" and this is triggered by stress hormones and elevated insulin levels. Restoring hormonal balance by managing our stress and dietary habits allows our bodies to repair and rejuvenate. Mindfulness and breathing habits, intermittent fasting like 16-8 or even OMAD, and low carb or keto are key for a natural solution.

    • @Izakokomarixyz
      @Izakokomarixyz 6 หลายเดือนก่อน

      If accumulation of cellular damage is the main reason then why is Andy milonakis still looking quite young for being almost 50? You would expect him to show obvious signs of skin damage from almost 50 years of being alive. Anyway I think the information theory of aging makes more sense.

    • @swenic
      @swenic 6 หลายเดือนก่อน

      I don't know who that is. In order to look younger than your peers one can do a few things including regular exercise. If your'e interested in the biological age you should at the Horvath's clock or similar biological indicators of age.
      What is the "information theory of aging" that you mention?

  • @ReinventingRogerOsorio
    @ReinventingRogerOsorio 7 หลายเดือนก่อน +22

    Wow, imagine how bad age discrimination will be when you turn 100 years old and still show up to the office…

    • @Invertatude
      @Invertatude 7 หลายเดือนก่อน +8

      ok boomer LOL

    • @guitarsoundsaround
      @guitarsoundsaround 7 หลายเดือนก่อน +5

      AI will replace so many people in the next decade.
      I’d prefer to live doing what I love.

    • @M.Evra91
      @M.Evra91 7 หลายเดือนก่อน +5

      At that age, you would have already accumulated enough wealth to be self employed

    • @dencsyy
      @dencsyy 5 หลายเดือนก่อน +2

      I mean, if you could be "young". Living and working as a 30 years old at your age of 100. I don't think that anyone would mind it.
      + it's not a rule to fall behind with technology and new stuff in life. For example my grandpa was really young minded. Played video games and was always curious about the future and new stuff. Let's be as open as possible, not just for new stuff but for everything. People, life, let's be as friendly as possible with each other :) hopefully we will live this reverse aging technology.

  • @danivega.a
    @danivega.a 5 หลายเดือนก่อน

    Really interesting video about living longer and maybe turning back the clock on aging. It talks about the cool science stuff happening right now. Can we actually reverse aging? The video breaks down the science behind it, like messing with cells and genes. It's pretty mind-blowing to think about how technology and medicine might help us live longer and healthier lives. The video also brings up some big questions about what this could mean for society and how we think about getting older.

  • @ResidualSelfImage
    @ResidualSelfImage 7 หลายเดือนก่อน +5

    altering the gut microbiome alters the kind of Nutrional absorption and the efficacy of that absorption which can be negatively impacted by medically or dietary introduced antibiotics. Keeping old people alive longer will tax the current retirement system or will prevent upward economic mobility of young workers in the current centralized big money economic system.

    • @truth8422
      @truth8422 7 หลายเดือนก่อน +2

      You're completely missing the point. The goal isn't to simply keep them alive longer. It's to keep them alive AND healthy, which means they can remain productive and retire later. It also means they're using way less healthcare resources thereby further reducing the burden on tax payers. This is a compete no brainer.

    • @mihalydesposito5466
      @mihalydesposito5466 7 หลายเดือนก่อน

      ​@@truth8422 well, purely from the perspective of retirement funds and economic growth, depending on how the life extending technology manages to help also remain productive, it might be a huge boost. I wouldn't be so fast on that though, considering the video completely skipped the psychological point of view. which is hugely impacting on actual productivity. Healthy and energetic, okay, but is that all a human is? How about adapting to new technologies, lifestyles, and generally just being tired of your job (people live longer and healthier already, still what happened when in France they tried to push retirement ahead?), how about mental agility (the older you are, the harder to learn, is this aslo going to be improved)? and even if people end up working, let's say until their 90s, I would really not undervalue the impact that all would have on economic mobility. if the technology plays out well and old people remain to use their lifelong expertize to add value to the economy, that might actually risk increasing the viscosity, if not straight away crystallising (depending on effectiveness) the present economic and power structures

  • @cappybenton
    @cappybenton 7 หลายเดือนก่อน +1

    Wunderbar

  • @paulreynolds2569
    @paulreynolds2569 7 หลายเดือนก่อน +2

    But, I wonder how the issue of simple wear and tear on the body is addressed in aging, as the years go by? Not all age-related ailments are intracellular. The interaction between different cell types/masses and extra-cellular damage that accumulates over time, isn't going to be repaired by simple reversing of aging within cells(?) Just as a physical injury has to be attended to medically, at ANY age. Microinjuries within and between tissues, accumulate over time. How would reversing the age of cells address the changes in tissues incurred by such accumulating microinjuries?

    • @nedames3328
      @nedames3328 2 หลายเดือนก่อน

      Younger cells are better at self-repair and maintaining the body.

    • @paulreynolds2569
      @paulreynolds2569 2 หลายเดือนก่อน

      Thanks for helping to clarify.
      So, I understand that because cells are younger they will be better at repairing injuries accumaled over time, but what about alterations to physical structures to tissue masses due to injury/accumulated injuries("wear and tear")?
      An example would be a PVD(posterior vitreous detachment, which I have in the left eye). PVDs are common after age 50 due to gradually shrinking a vitreous humor and leave you with additional floaters and "flashing light" sensations. You could reverse the age of the involved cells, but what would actually "reattach" the vitreous to the back of the eye(other than complex surgery)? Reversing the age of cells would perhaps normalize the vitreous to a more normal volume and hydration, but it is still going to remain unattached to the back of the eye. @s3328

  • @davidwilfand916
    @davidwilfand916 3 หลายเดือนก่อน +1

    I am very happy at the overton window shift that is occuring in the anti-aging space.

  • @eddyr1041
    @eddyr1041 7 หลายเดือนก่อน +1

    We need much progress in these ....
    Too much ageing pop need solutins for ourveconomi

  •  7 หลายเดือนก่อน +1

    Not a single mention of Telomere treatment. Wow!!!

  • @user-cy5yu8ng6f
    @user-cy5yu8ng6f 7 หลายเดือนก่อน +2

    תעשה סרטון על האם דרך המשי הייתה גם ברומא

  • @marioesteban7477
    @marioesteban7477 4 หลายเดือนก่อน

    The concept of slowing down the aging process through scientific techniques like fasting, epigenetic reprogramming, and parabiosis sparks intriguing possibilities. The mention of these methods raises questions about the potential for realizing a "Peter Pan" dream of staying perpetually young. The intersection of science and aging opens up exciting avenues for exploration and raises hope for innovative approaches to enhance longevity and well-being.

  • @user-ko4fe3mx4j
    @user-ko4fe3mx4j 4 หลายเดือนก่อน +2

    Living longer could give people more time to do things that they like, many people spend their live working, they don´t have enought time to get fun, visit other countries, create memories with their families. Ageing and mortal illness are inevitable now but what if we could slow down ageing or find a effective cure for cancer, we could enjoy more the life instead of being worried about when would be the end.

  • @CamelxRavenNova2
    @CamelxRavenNova2 6 หลายเดือนก่อน

    Bryan Johnson is awesome

  • @MarcEsadrian
    @MarcEsadrian 7 หลายเดือนก่อน +17

    Hold on for now, if you're older. Do everything you can to extend your lifespan, but even more so, the span of your health: the window is almost here. Research new supplements (GlyNAC, for instance) and established ones (magnesium, creatine, and omega 3), as well as engage in healthy lifestyle choices (eating right and exercising). Stay with us until we solve the riddle entirely.

    • @dencsyy
      @dencsyy 5 หลายเดือนก่อน +2

      Thank you, it was really calming to read this :) I'll focus on keeping my self healthy as long as possible.
      I'm looking forward about the near future. Hopefully we will live this day, when aging will be reversable. I would love to live more, experience more and even learn and study new subjects. After being a 2D animator and graphic designer for a few years I've been wondering all the time what would it be like to work as a scientist. If I could have more time to do both of my interests in my life. I would like to entertain and to even help people. It would be amazing if this reverse aging thing is real. I hope it is.
      Until then, stay healthy my friends. Keep yourself safe and I hope you're happy in most of your days :)

  • @Melanie____
    @Melanie____ 4 หลายเดือนก่อน

    A whole food Plant based diet will positively impact epigenetic expression to aid in longevity as well as work in a number of other anti aging pathways

  • @yv3009
    @yv3009 7 หลายเดือนก่อน +4

    Even from this video : "Unfortunately, not".

  • @jessferreyra5607
    @jessferreyra5607 4 หลายเดือนก่อน

    Exploring scientific methods like fasting, epigenetic reprogramming, and parabiosis for anti-aging raises interesting possibilities. However, some caution that pursuing rejuvenation and very long life for humans could threaten civilization. Those in power may actively work to limit average lifespans to preserve societal stability. Additionally, accessing longevity secrets may come at a significant cost, adding complexity to the ethical and practical considerations of extending human life.

  • @Reaklibert
    @Reaklibert 7 หลายเดือนก่อน

    It's weird that David sinclair isn't in this video.

  • @ashaharyani7733
    @ashaharyani7733 4 หลายเดือนก่อน

    Nice channal thx utube team 😊😊4m Pakistan 🎉

  • @ashaharyani7733
    @ashaharyani7733 5 หลายเดือนก่อน

    Nice information sharing ❤❤ ❤😊 from Pakistan thx 🙏 utube whole world 🌎 salute u

  • @longtimelo
    @longtimelo 4 หลายเดือนก่อน +2

    Wish all that money and effort would instead go to curing cancer, diabetes, heart disease and addiction

  • @dreamville2293
    @dreamville2293 7 หลายเดือนก่อน

    I’ve heard that Anthony Bourla is an Aldabra Giant Tortoise.

  • @pepitoperez594
    @pepitoperez594 7 หลายเดือนก่อน +22

    Honestly I would like better to stop having the fear of death. I hate to have panic attacks about it. About how much painful it could be, or the feeling about not sharing with my love ones ever again or experiencing anything else for the rest of eternity. How can science help me remove this evolutionary trait that makes me and my body want to live? How to make dead much less painful?

    • @bulkierwriter2772
      @bulkierwriter2772 7 หลายเดือนก่อน +7

      You need to stop being scared of the inevitable, and let go of your ego, nobody deserves eternal life and this will backfire, imagine how powerful dictators will be and how politicians will dominate generations, wealth will only build and solidify into those who already own it. You want to work and pay taxes longer?

    • @B8ffakaduck
      @B8ffakaduck 7 หลายเดือนก่อน +11

      The only sad thing about death is the people you leave behind. But with time, they will also be fine.
      There's no reason to fear it, it will come. All you can do is use your time the best possible way until the inevitable knocks at your door

    • @pepitoperez594
      @pepitoperez594 7 หลายเดือนก่อน +2

      @@bulkierwriter2772 exactly, I don't want to live forever. Instead I would like to live without the fear of death. However, it is codify within our genes after millions of years of evolution, and it has to be that way because if living things don't have the "natural urge to stay alive " then life as we know it wouldn't be posible. I understand why people would like to live a few years more, specially if we can stay younger for longer. But living forever would not solve any problem. I even think death help us give meaning to our lives, make us appreciate it more.

    • @perfectallycromulent
      @perfectallycromulent 7 หลายเดือนก่อน +3

      you seem to be having a focus on this at a level that is both very distressing for you, and beyond what most people experience. you may need anti-anxiety medication or other medical treatment here.

    • @pepitoperez594
      @pepitoperez594 7 หลายเดือนก่อน

      probably yes, but I'm unemployed so I can't afford it though :V@@perfectallycromulent

  • @shueydj
    @shueydj 7 หลายเดือนก่อน +1

    Nicotinamide riboside + pterostilbene to juice epigenetic remodeling and DNA repair. Its the sirtuins ... at least partially.

  • @Dan-uf2vh
    @Dan-uf2vh หลายเดือนก่อน +1

    8-12 years for partial cell reprogramming resulting in a net longevity escape velocity for the relatively healthy. 20 years for *full* rejuvination. Both may happen sooner depending on how well AI accelerates biotech and how easy reversing aging turns out to be.
    It will probably take 30-40 years from now to also structurally reverse aging so that you *look* 20, because otherwise you will be carrying around some misshaped skin and bone. If full sci-fi nanotech is needed for restructuring, this might actually take 50 years.
    In any of those cases, a bright future awaits most people who can live healthily for the next 20 years into the new age.
    Personally, I look forward to having a biology which I simply never got to enjoy in my youth as I was constantly having a headache or the flu, as well as full of stress and dissatisfaction. When genetics are no longer a limiting factor, we can finally be equal and free.

  • @nufrepusgnirbi
    @nufrepusgnirbi 7 หลายเดือนก่อน +10

    Live longer? I can’t afford that 😂
    And I already had enough at 31.

    • @rtm1619
      @rtm1619 7 หลายเดือนก่อน +2

      The people at the very top made you feel this way, they'll be very happy their plan is working

  • @JJV7243
    @JJV7243 7 หลายเดือนก่อน +48

    The vast majority of aging can be greatly slowed down by improving our DNA repair enzymes and ensuring our telomeres maintain a decent length. However, certain cells cannot replicate or regrow once you get old (nerves/muscles) thus we'd need stem cells to do that. However, there are also non-enzymatic chemical reaction byproducts that form within your cells that are irreversible - these will always cause us to "age".
    Most of these improvements would require fully genetically engineered humans to actually function/work, which is quite far off at the moment.

    • @bulkierwriter2772
      @bulkierwriter2772 7 หลายเดือนก่อน +4

      Hopefully it’s never a possibility.

    • @blink182bfsftw
      @blink182bfsftw 7 หลายเดือนก่อน +11

      ​@@bulkierwriter2772honestly yeah can you imagine tyrants living forever? Terrible for the world

    • @joaopaulopeluzio4195
      @joaopaulopeluzio4195 7 หลายเดือนก่อน +5

      Actually, with partial reprogramming you can rejuvenate neurons to a youthful state, the problem is that the capacity of the brain is limited, even if we can maintan a youthful state forever this will reach a informational limit sooner or later, that is why synthetic biology is so important and this field is also growing very fast

    • @bulkierwriter2772
      @bulkierwriter2772 7 หลายเดือนก่อน +3

      @@blink182bfsftw Yep that’s what I’ve been telling people, along with their AI robots, and congress would stay the same and wealth would further consolidate into fewer hands.

    • @hoangle2483
      @hoangle2483 7 หลายเดือนก่อน +24

      @@blink182bfsftw how about the other way around? smart, kind hearted people now can live longer to contribute to society ?

  • @Atombender
    @Atombender 7 หลายเดือนก่อน +3

    You will age, mortal!

  • @MiguelGarcia-pz9tr
    @MiguelGarcia-pz9tr 4 หลายเดือนก่อน

    We all wish to live longer, genetic studies are advancing incredibly fast, this is a great opportunity for those who wish to do more things, such as adults, those who wish to make amends for their mistakes and finally those who wish to conclude something of their lives.
    Undoubtedly science is making a great contribution in this field.

  • @DharmendraRaiMindMap
    @DharmendraRaiMindMap 7 หลายเดือนก่อน +2

    The desire to live forever will live forever

  • @koiyujo1543
    @koiyujo1543 5 หลายเดือนก่อน

    we could change genes like using the technology CRISPR but that's not yet fully protected but were getting close it's just the matter of when?

  • @avi6579
    @avi6579 6 หลายเดือนก่อน

    Very well then

  • @hjtam88
    @hjtam88 7 หลายเดือนก่อน +3

    Forever young, I want to be forever young.....

  • @xg_zack
    @xg_zack 7 หลายเดือนก่อน

    Its unwise for and economist to say impossible. Consider it fundamental to their job to make it possible.

  • @user-cy5yu8ng6f
    @user-cy5yu8ng6f 7 หลายเดือนก่อน +1

    תעשה סרטון על איןציקלופדיה

  • @kuntalgo
    @kuntalgo 7 หลายเดือนก่อน

    But do the lobbying Healthcare and Pharma companies actually want the old-age related medical expenses to decrease?

  • @Gopnikawa
    @Gopnikawa 5 หลายเดือนก่อน +5

    I’m currently in the process of writing a story about some man who was imprisoned for a crime he didn’t commit… for over 40 years… since he was 18 years old. The bitter old man rejected all forms of help and support, be it massive sums of money or emotional support. He was hellbent on never accepting getting old in prison and defying the odds of time itself to regain a youthful body and exuberance at all costs… to the point that nothing else this world has to offer would’ve changed his mind; not even a promise of unlimited power over the world.

    • @kanakalatahembram1650
      @kanakalatahembram1650 5 หลายเดือนก่อน +2

      Plot twist: the jail was standing over an Ancient cave where there existed....."the fountain of youth" 😜

  • @thinkhine8866
    @thinkhine8866 6 หลายเดือนก่อน

    My father passed away 90 ,my mother passed away 78.( father and mother passed away not for aging but my mother had C liver disease and my father had chocking ( homcare person careless problem).

  • @thinkhine8866
    @thinkhine8866 6 หลายเดือนก่อน

    Can it anti aging ?

  • @arttoegemann
    @arttoegemann 2 หลายเดือนก่อน

    My feed list led this with The True Cost of Aging, same source, that discouraged aging. 😅 I have not seen this video yet. Does it mention the Yamanaka factor? (Yes.) Much, much longer human lives are about to happen. Prepare public health policy, create a new healthcare.

  • @antoniobortoni
    @antoniobortoni 7 หลายเดือนก่อน

    mmmm In the pursuit of rejuvenation and longevity, cutting-edge science champions a harmonious blend of intermittent fasting, consistent exercise, and an enriched diet full of antioxidants like blueberries and green tea. Moreover, supplements such as Lion's Mane mushroom stand out for their potential cognitive benefits. Embracing these habits not only promises a life of extended years but also one of vibrant quality, urging us all to lean into a future where we age gracefully and mindfully...

  • @hawarnajar3117
    @hawarnajar3117 7 หลายเดือนก่อน +1

    Brave new world

  • @MauroRincon
    @MauroRincon 6 หลายเดือนก่อน

    Still fail to see the point to try stopping or reversing aging (treating deseases is a different thing). Dying gives life a sense of urgency and worth. On the other hand, we are in the midst of the greatest generational wealth transfer in history: from the young to the old. Can you imagine if the old (and most likely the well off old) lived to 150 or 200? This can only be possible with a deep restructuring of society, that specially the old are unwilling to go through. Btw, I'm not young.

  • @MichaelKuwa
    @MichaelKuwa 7 หลายเดือนก่อน

    By "near starving" do they mean extended fasting ?

  • @zacchk
    @zacchk 7 หลายเดือนก่อน

    So NMN is useless?

  • @patpatlau2048
    @patpatlau2048 2 หลายเดือนก่อน +1

    A better question would be: should it be?

    • @demos1936
      @demos1936 หลายเดือนก่อน

      would you be able to question that if u were dead?

  • @robwyyi
    @robwyyi 7 หลายเดือนก่อน +8

    Eat less, eat only within a small window of time(8 hour window) be skinny, sleep well, stay hydrated. What can science add to it. Not much just prove my examples.

  • @18klan12
    @18klan12 3 หลายเดือนก่อน

    I'm 40 and I volunteer my body for this ageing process.

  • @colinburgess7728
    @colinburgess7728 5 หลายเดือนก่อน +1

    A man was asked by a reporter the secret of his old age
    after much thought he replied "I guess it must be on account of being born a long time ago"

  • @pinguinobc
    @pinguinobc 7 หลายเดือนก่อน +28

    At present we have the ability to slow aging through diet, exercise, supplements, and a few interventions such as parabiosis.
    We may one day be able to stop aging, or slow it to the point where it's close to stopping.
    We can reverse some of the effects and symptoms of aging, but I would be surprised if we can actually reverse aging altogether (e.g., a 60-year-old becoming 20 again). Removing all the accumulated damage to our cells or replacing damaged cells with new ones would be extremely difficult. You could do it locally, perhaps, but in the entire body? Unlikely. We should be able to reach the point where we can replace aged and damaged organs with new ones, though.
    It's conceivable that in the not-too-distant future, we will see people living to 150.

    • @roryblake7311
      @roryblake7311 7 หลายเดือนก่อน

      Thanks, yes!

    • @guitarsoundsaround
      @guitarsoundsaround 7 หลายเดือนก่อน +1

      Scary really. What age is old? And who can afford it? (To live a healthy lifestyle for that many years)
      Glad I’ll be long gone by then. 🙂

    • @weppwebb2885
      @weppwebb2885 7 หลายเดือนก่อน

      To slow aging is not about getting less wrinkles, it's about your body being able to maintain its power to self repair. So you should not have to replace cells yourself, your body should deal with most of the additional damage. I doubt it will help against cancer though

    • @escatel6889
      @escatel6889 7 หลายเดือนก่อน

      Viruses may be the way to access the whole body.

    • @Izakokomarixyz
      @Izakokomarixyz 6 หลายเดือนก่อน

      @@weppwebb2885- I have high hopes for AOH1996.

  • @Continentalmunkey88
    @Continentalmunkey88 4 หลายเดือนก่อน

    Upto 65 or 70 but multilevel marketing firms are very experienced with age pyramids within cities

  • @jellyfishdao
    @jellyfishdao 5 หลายเดือนก่อน +2

    Heck yeah! Jellyfish can do it, why can't we?

  • @EnchiladaBoredom
    @EnchiladaBoredom 19 วันที่ผ่านมา

    I cannot bypass my community for this one here, im afraid. The town is complicated next door and it complaints. Thanks anyway,

  • @etaokha4164
    @etaokha4164 6 หลายเดือนก่อน

    Am 27 and came across your documentary. Thanks.

  • @stickplayer2
    @stickplayer2 7 หลายเดือนก่อน

    "Aging". Spelled wrong in title, and in text description.

    • @roblake602
      @roblake602 7 หลายเดือนก่อน +1

      British spelling...

  • @TeddyshaCelestine
    @TeddyshaCelestine 2 หลายเดือนก่อน

    Yes it can.

  • @videofrat3115
    @videofrat3115 2 หลายเดือนก่อน

    I would love to know more about that 98 year old woman. What is her diet? What is her daily routine?

  • @rerikm
    @rerikm 5 หลายเดือนก่อน

    why nothing is mentioned regarding mental health?
    I guess people would go nuts after having lived for 140 years.

  • @typerightseesight
    @typerightseesight 7 หลายเดือนก่อน

    only with the finest brandy. or gin by ryan reynolds. lol. brought to you by mint mobile.

  • @thinkhine8866
    @thinkhine8866 6 หลายเดือนก่อน

    Amazing it ,some people believe it ,youngest blood can change older people blood. Is it really?

  • @somecuriosities
    @somecuriosities 7 หลายเดือนก่อน +1

    02:30 'Life Force' by Tony Robbins..? Yikes!

    • @xnlo
      @xnlo 7 หลายเดือนก่อน +1

      Yes witnessing that brought the integrity of this video down.

    • @michelzou2896
      @michelzou2896 7 หลายเดือนก่อน

      @@xnlowhy is that?Is this man a crook?

    • @Nuttymike
      @Nuttymike 7 หลายเดือนก่อน

      Haha! Nice eye, these people are crocks.

    • @superblondeDotOrg
      @superblondeDotOrg 7 หลายเดือนก่อน

      @@michelzou2896 Tony Robbins is definitely a crook and a scam artist. Uses fallacy and magic tricks to fool people out of tens of thousands of dollars with false promises of life improvement.

  • @gabibmw
    @gabibmw 7 หลายเดือนก่อน +1

    A whole food plant based diet, exercise, sleep and have a life with purpose.

  • @brianrcVids
    @brianrcVids 6 หลายเดือนก่อน +1

    The longest-lived populations on Earth (Blue Zones) had diets that were all 95-100% plant-based.