ฝัง
- เผยแพร่เมื่อ 5 ก.ค. 2024
- Malaria is one of the oldest diseases in human history, dating back to ancient civilizations in Greece and China. It has even been attributed to aiding the fall of the Roman Empire.
So if we’ve been fighting malaria for so long, why haven’t we been able to stop it?
____________________
SICK is a new series that looks at how diseases actually work inside our body. We'll be visiting medical centers and talking to top researchers and doctors to uncover the mysteries of viruses, bacteria, fungi and our own immune system. Come back every Tuesday for a new episode and let us know in the comments which diseases you think we should cover next.
____________________
Read More:
Unraveling the 3D genome of human malaria parasites.
www.ncbi.nlm.nih.gov/pubmed/3...
Malaria parasite transforms itself to hide from human immune system
www.hsph.harvard.edu/news/fea...
Malaria and the liver: Immunological hide-and-seek or subversion of immunity from within?
www.ncbi.nlm.nih.gov/pmc/arti...
Le Roch Malaria Lab at University of California, Riverside
lerochlab.ucr.edu/
Visit the Seeker website www.seeker.com/videos
Subscribe now! / subscription_c. .
Seeker on Twitter / seeker
Seeker on Instagram / seeker
Seeker on Facebook / seekermedia
Seeker www.seeker.com/ - วิทยาศาสตร์และเทคโนโลยี
![[Live] : ONE FIGHT NIGHT 23 วันนี้!! “เร ยุน vs อาลิเบก”](http://i.ytimg.com/vi/ClLQVYWSrUk/mqdefault.jpg)
Honestly the devs should make mosquitoes a bit larger and slower so it'd be easier to kill
Too OP pls nerf..
not even all the balance patches could stop them...what an overpowered class man
@@Bolter024, genuine question, what does nerf stand for?
sounds like tierzoo
@@yatint9665 in gaming terms it means de - powering something
If there's a symbiotic relationship between mosquitoes and humans, why not just genetically modify the mosquitoes so that they don't get infected? Wouldn't that stop the cycle?
That's actually a solution that's being used! I don't remember the specific study or where this is taking place in, but I'm pretty sure there are attempts to genetically modify mosquitos with the dominant gene of being unable to carry malaria so they can be released into regular mosquito populations and curb the spread of malaria!
Singapore
Yah! Humans are great at messing with nature!!!
They have done that,
Vaccine mosquitos would be pretty dope
*It's a me MALARIO*
and me, poliuigi!
COPIED FROM ANOTHER VIDEO.
@@Foxtalee who the hell cares
Game mechanic: jump under red blood cells to replicate and destroy your computer by lag
Itsa me, whoopalugi
I'm a medstud from asia and the answer of why malaria so hard to eradicate, actually more related to the mosquitoes than the abilities of plasmodium to change protein marker.
Especially in humid area in most of the lower hemisphere like south east asia and most of south part africa, its become mosquito endemic place due to geographical factor. How on earth you eradicate the mosquito without also eradicate ecosystem there.
So most of us medstud that will be work in endemic area of mosquito just prepare to treat the patient with purpose of destroy and suppress the cycle life of plasmodium in human body.
FYI most of people that live in endemic malaria area already exposed and some infected by malaria but doesn't show any symptoms whatsoever
_try edit DNA _*_th-cam.com/video/OI_OhvOumT0_/w-d-xo.html*
@@thanglaka9543 yeah, maybe we could try it in about 10 or 20 years from now, it actually at this time the field of gene editing not as sophisticated as the media talks about. Also not cost effective in period.
Eradicating a species isn’t done lightly. Lots of research goes into potential ecosystem impact. I know this vid is about malaria, but you seemed concerned about the ecosystem impact of eradicating mosquitoes. Don’t lose sight of the larger picture: Mosquitoes are one of the deadliest animals (or inverts) ever known to man, as they’ve killed so many people, as well as transmit a myriad of diseases. The rationale isn’t eradicating malaria only; currently humans can avoid contracting the virus with antimalarial pills, there are people w malarial immunity, and malarial symptoms can be treated. The more important reason to eradicate these mosquitoes is because they transmit some nasty diseases which cannot be geographically contained. They have the ability to transmit many nasty diseases: Zika, dengue, West Nile virus, chikungunya, yellow fever, Japanese encephalitis to name only a few; the list is extensive.
With advanced in modern technology, it’s difficult to control their range; mosquitoes are all over the world. So even if some groups of people are immune to malaria, the risk of other viruses/diseases that can be contracted and spread is alarming.
For example, you might be immune to malaria, but you might not be immune to Zika. If you and your partner are trying to conceive, you could pass along this to your baby, resulting in congenital defects and sometimes even death. Another example w Zika (b/c most people have heard of it): even though you’re immune to Zika, but go on holiday to Vegas and decide to get married, you could pass on Zika to your new wife (who’s never been to Asia), and also your future kid (I’m thinking short time frames here, since Zika can clear the body after some time). The same example could be applied to a businessman. He might be immune to malaria, but contracts Zika while on holiday in Hawaii. Then passes it along to his wife or girlfriend. The consequences can be devastating.
Some pregnant women in high-risk areas weren’t even leaving their houses for fear of contracting Zika. I recall hearing about this in Florida - basically swampland, teeming w/ mosquitoes.
Since only a specific mosquito species transmits these diseases, it makes sense to target and eradicate only this specific species. The potential ecosystem impact outweighs the benefit. Added benefit is that you’ll get less bites since there’ll be less mosquitoes in general.
Malaria transmitting mosquitos are a specific species (aedis aegypti). This species also transmits chikugunya, dengue, Zika, and yellow fever. Scientists are figuring out how to gene modify the males of this species specifically, to be sterile, so females can’t produce any offspring and the species will eventually die off. However, they’re only targeting this specific species, not all mosquitoes. So there will still be other mosquito species out there, annoying people the world over and contributing to a vibrant ecosystem.
Sure, the ripple effect by eradicating a subspecies could be bad, but it won’t be catastrophic. For example, in Asia there is the Asian Tiger Mosquito (aedis albopictus), which also can transmit Zika, dengue, yellow fever, and could take over if a. aegypti is eradicated. They’re hardier and just as widespread as a. aegypti. But a. albioictus is less likely to bite humans after feeding on one (will infect smaller animal). Now, if scientists eradicated both species, we might be looking at an issue.. But there are more than 2 species of mosquitoes. And if another species can fill the void, without being a vector, than that’s a win. However, if scientists find out that aedis aegypti eradication is more significant than anticipated, they can always bring back the species via cloning (see de-extinction). IMHO, the risk not to eradicate is worse than the alternative
@@laughingc0w sorry, but am i supposed to reply this 7 paragraph comment. I read it but if you dislike my comment or something i am sorry it doesn't matter.
I am just some random guy from internet. :)
I'm a music producer, I wondering if there's a way to repel this insects using sounds.
Does the parasite display an infinite amount of protein masks, or do they often display the same ones over time? For example, I'd be looking for repetitiveness of the results and then once a computer can learn and log all the versions of it's masks, maybe there would be a way to teach the lymphocytes to have a preemptive attack. I don't know much about how this science works, but I would assume someone has already thought of this and hit a barrier of some sort. I have a feeling this is one of those things an AI is going to help solve.
Is a parasite btw.
@@viceralman8450 ty, my bad, ill edit
I guess at a certain point they repeat, but maybe not all instances of mutation would. (Remember, a lot of the parasites are evolving their masks at the same timw an likely would not result in the same mask). This would explain why some people over time can overcome the parasite where the immine system finally gets one step ahead of the mask race.
But for a universal vaccine to be made, you'd need to be able to identify all the possible protein masks and find what they have in common, without being too common in that your immune system will target clean cells such as the liver or RBCs. If you target a mask that is too common, you'll probably end up with either a dead liver or anemic blood.
There is this guy who is now using AI to try designing vaccines. Try searching for the guy who made himself immune to snake venom and this scientist AI guy who's making a universal antivenom.
Come on immune system! I guess if you want something done right you have to do it yourself.
that's where sickle cell comes into play. That is the body's way in fighting it. I have it.
It's amazing how an organism without a brain can grow and adapt
Seriously look at most of the people in the world
@@ajhproductions2347 .
@@ajhproductions2347 😂😂😂
And yet, people don't believe in evolution
Can you guys do an episode about dengue ?? That is also interesting
As a nurse, seeing ungloved hands performing an injection at 4:01 makes me cringe hard.
Why
Gloves are not necessary for i.m injections
Malhairia - bad hair day. For some people is a crippling disease.
@2:23 "jokes on you, biiitch" = Sickle Cell
R Smith i get this lmaoo
Interesting thanks for the video!
Good video
can you do a similar video to other diseases or cancers it would be interesting
Yeah, let us know which specific diseases you'd want to see and we'll add it to our list.
She needed subtitles imo
Not really
@@birddude3123 a little bit lol
you said it snacks on haemoglobin but what if you have methemoglobinemia?
So if we give protain shakes to moscitos we can stop malaria?
Do an episode on ME/CFS
I wonder if sickle cell patients could find any relief from their pain if a mutated version of the parasite that carries the proteins was introduced to their body.
I was bitten when i was a baby and got malaria,somehow i survived.
My mom survived it too.
i have survived iitmultiple times over
@@lefthanded5473 same
they should make an episode about eastern equine ensephilitis [EEEV]
Good title.
My god I was just researching malaria yesterday, the coincidence lol
OMG me too!... just kidding lol
I wrote a proposal to BG Foundation some years ago to contribute my idea to reduce or eradicate the vectors but did not get accepted perhaps I did not have enough data to support my claim or other reasons. I will try it again to get more data in the future.
Hi how may I get subtitle for this channel, kindly advice how may I go about it. Thanks
She looks so much like Fabiola Gianotti, Director-General at CERN
I figured the dude from farcry 2 could just rip out the malaria the way he heals himself
I'll just bathe in anti-bug spray for three weeks straight when I'm on vacation in SE Asia, ain't no mosquitoes biting me then
Am i tje only person in the planet that when I hear the word "suck" i think something dirty LOL😂
Can you talk about the disease called Nagleriasis that is caused by Naegleria fowleri? It would be interesting to know about it.
What came first the infected human or the infected mosquito?
So honorable
well that is rough
The vector control board ate all the mosquitos, flies, bees, moths etc.
Thank God for the subs
I think they forgot the title
please do Helico bacter pilori
Isn't there adaptions humans have for malaria? Sickle cell and another blood cell condition. Is that not possible to use this natural solution as a guide for an artificial solution?
Do you know we Tharu people living in Nepal are malaria resistant🏋️♂️💪
Really? How so?
@@hunterhealer8022 it's because of sickle cell anaemia
@@saurabtharu7252 yeah okay. But SSA is itself one hell of a disease
@@hunterhealer8022 at past many tharu people used to die of malaria daily because we are the residence of Terai area which was used to be almost forest...with time we get adopted with malaria and we get SSA which is very bad.
@@hunterhealer8022 I told resistant but it doesn't mean fully resistant but almost most of the Tharu people don't get affected by malaria
How about an older seeker video I saw about genetically modified mosquitoes that kill the offspring of mosquitoes.
I think syphilis has been around longer than malaria
What's the "new discovery" you touting in your advertising this video????
This series is sick
Far cry 2 taught me about this disease.
Well that's the only good thing about having sickle-cell is I don't have to worry about malaria. I could have made a killing during the Panama Canal construction lol..
👋🏼👋🏼 hey fellow warrior!!!
00:42 we are twying to find a new way to combite ta disease
How many people have had malaria?
Got malaria 5 times already :(, when I was living in the Amazon Forrest area.
OMG
@Jenny Widmer not really pal it can be destroyed with proper medication
Roman empire: *I'm inevitable*
Malaria: *hold my milk*
My grandpa had malaria and dengue fever when he was drafted to Guam I'm WWII
Hi WWII xd
Subtitles would have been nice...her accent is pretty thick.
Please make video on how close are we to build iron-man arc reactor
Far, containing any reaction that strong is beyond portability.
Lmao
Why is nobody talking about the title?
I love her accent 🤩
Who else had to put captions on to understand that dr chick
Louisiana scared now 😅
I had malaria more times than I had a hot dinner I have one as I'm writing this...
Pretty sure the image at 0:55 is a male Anopheles, which do not spread malaria since they don't sting.
I hate mosquitos:-/
What's the rate of infection in the US? Or the areas of incidence
As an Indian watching from India, I just want to say, "Santosh! Go get me a croissant (pronounced the French way), we have a French here"
She work on curing disaesea,she have a French accent,omg she's curie.
My favourite Fallout 4 companion :3
Exactly what I was thinking. XD
You must be Vault-Tec security. Do you have the authority to release her from her lab? :P
At least the malaria mosquitos in Fallout 4 are BIG and SLOW, nothing a rocket laucher can't take care of. Plus they have such an exotic deliciout meat. Feast for the whole family.
i got malaria in new guinea!
I contracted cerebral malaria I’m broken
Malaria scares humans and Far Cry 2 players
Only small percentage of mosquitos are actually malaria mosquitos
Okay but I just went on a wild goose chase trying to understand rabies in modern times and there are some survivors out there!!! Modern medicine has cool things like induced comas and synthesized antibodies to help us. Plus I thing it’s worth mentioning the first recorded survivor was a unvaccinated woman!
Bacteriophage is our best bet
MORE DDT FOR GOODNESS SAKE
Bruh in every video our immune system is weak asf and like anyone can fool them.
Well yeah, the world is not a simple place.
So what makes malaria so hard to fight??
Watch with comprehension.
@@kororopocoro4935 2:59 So it is hard to fight because the malaria virus quickly changes its mask against the human immune system??
That's it??
That is not a particular characteristic of only the malaria virus. Plenty of diseases do that.
I was expecting a more unique quality of the malaria fiend.
@@IvoPoblete It's not a virus.
Can we get a video about what the money is used for when we hear that it takes thousands or millions for a team to possibly find a cure to a disease or virus
Ehmmm......the title suggests a new disvovery against malaria......
I did not see one.....
These stories are failing to come up on my homepage! What's happening to TH-cam?
I hate Mosquitos more than Cigarettes!
Malaya
I'm sorry but I understood next to nothing when the scientist was speaking...
Don't be sorry! Learn to listen, or least turn on CC.
What is up with your name???
My dad: **eats**
Mosquito: wait that's illegal
SICK S01 EP005 MALARIA YT
_niiiiiiiiiiiiice_
Lead poisoning also contributed to the fall of the Holy Roman Empire
*And I thought Jesus made the temple fall..*
You could have used your portal gun to find out by going into another dimension that has capability to time travel 😂😂
4:00 is it common to poke a needle like that😳
Depends on which medicine you receive, some need to be administered right under the skin, some are intra-muscular and can be injected deeper. And a spinal tap can get in your bone marrow so yeah, different needles and depths for different situations.
When you see that it has 420 views and ur like "these guys dont keep the bell on"
The one thing you can say about DDT is that it was REALLY effective! It did exactly what they wanted it to do, and more!
CDC used DDT, it's very effective. Enemy MALARIA fainted. :D
I hate mosquito
It's not, drink more vodka tonic, or gin and tonic if you prefer...
She needs subtitles
There are subtitles.
Far cry 2 is the most believable far cry game
Amen. And also... These mosquitos don't seem to realize they can't kill all of us....
Do you understand what I'm saying.... Nobody kills us...
*Nobody.*
Not sure why bring up DDT rather than genetic mutations that can make mosquito's extinct, but thanks for the video. It was good all in all.
Mosquitoes are important in aquatic ecology, also a lot of birds feed on them and other small animals. Genetic engineering to make mosquitoes extinct is impossible, because of the amount of mosquitoes in this world and natural selection, creating mosquitoes with modified dna is just a waste of time, because those mutations won't spread in the nature if the individuals that carry them die off, and there are millions of healthy mosquitoes reproducing daily.
@@jeminah6520 , honestly, I was thinking of most of this as I was writing the comments. I posted it anyway because I have heard multiple times over the years that genetic modifications can make them extinct. I don't know entirely what to think. I doubt they would genetically modify themselves to become immune because rapid evolution usually occurs in smaller and more simple forms of life. It is possible, but unlikely they would.
Imagine if genetic modifying killed most of the mosquito's in an area and there are still a few that managed to avoid the spread of breeds of genetic mutation. In that case they would be vulnerable to being extinct because of predators. Perhaps it would be more accurate to say genetic modifications would make them vulnerable.
DDT is dangerous to humam health.
So let's say you nearly died from malaria when you were a baby (like, few months old), do malaria still screw up your liver and body once you're an adult ?
Use Google lol
I got type 1 Diabetes a year after getting malaria. I’ve read a normal side effect is a major organ failing, I guess for me it was the pancreas.
Do they look at sickle cell and thalasenia diseases?
Here while "SICK S01 EP005 MALARIA YT" was the title
Today's fact: When watermelons are grilled or baked, they lose their granular texture and can even be used as meat substitute, a 'watermelon steak'.
Who wants a steak made out of watermelon😂😂, vegans get so desperate these days
Okay?
Mosquitoes are vegetarian...I got one drinking my blood rn.
Did you hear what she said right after that?
@@sal_strazzullo yeahh...only bitches suck bloods.
Weird seeing a channel with 3 million subs have a video with 100 views lol
It gives us casting speed 😂
0:29 I love that French accent
Why have a cure when its more profitable to just treat the symptoms?
While I was watching the sympthoms, a mosquito literally flew over my screen. Ain't that timing. Lucky me it was just a regular mosquito
If one needs the other to reproduce then what came first..the chicken or the egg?👆😕 either way, send on the nanobotz!
What kind of accent is that? Sounds like french with a lisp
Italian