Septic Shock
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- เผยแพร่เมื่อ 12 ก.ค. 2024
- sciencewithsusanna.com has diagrams, notes, and practice questions.
Sepsis, or blood-poisoning, can progress to septic shock.
Septic shock is a dangerous drop in blood pressure that may lead to hypoperfusion of tissues, cell damage, and multiple organ failure. It has about a 50% mortality rate.
It is most common in the elderly and the very young, or the immunocompromised.
Urinary tract infections, peritonitis, pneumonia, or skin wounds or cellulitis are the most typical infections that may progress to septic shock.
Gram negative or Gram positive bacteria can cause septic shock if their toxins overstimulate host white blood cells.
Endotoxin from Gram negative cell walls, and superantigen exotoxins from Gram positive bacteria can overstimulate host leukocytes. In particular, monocytes and T cells that are overstimulated start a cytokine storm that causes massive vasodilation (leaky blood vessels) and disseminated intravascular clotting (DIC). In this situation, blood pressure plummets from lack of fluid, and tiny clots form throughout the body. To make matters worse, the clotting factors are then "used up", and internal bleeding occurs.
Treatment involves stabilizing blood pressure as much as possible using IV fluids, aggressive antimicrobial treatment, and vasopressors such as NE, vasopressin, and possibly dopamine. Steroids may be given in some cases. Even those that survive septic shock often have brain damage and cognitive impairment from the hypoperfusion during the crisis. - วิทยาศาสตร์และเทคโนโลยี
Best explanation of sepsis/septic shock I’ve heard. Thank you.
Great explanation. To the point & easy to understand. Thank you once again Susanna🌺
Always love your uploads. I nearly developed sepsis when I had a ruptured appendix as a teenager and now I understand why- peritonitis!
PS The cats don’t take away anything from the video. It was a charming interlude 🐱
Thanks to your videos I was accepted to the Nursing Program and I still love watching your videos ❤️thank you so much!!
Great explanation! Thank you Susanna
I really enjoyed this video. Very visual with colors and a great explanation. Came for a quick review. Thank you!
EXCELLENT VIDEO!!!GOOD INFORMATION!!!BEAUTIFUL HANDWRITING!!!
Thanks for video! Explains it very clearly!
Awesommme.... thanks a lot... very well explained.... ,😊 made that too easy and clear.
Thanks for the video ! When I'm tired of reading my notes again and again it's really pleasant to come here because you really simplify the problem and it clears the mess in my mind before I have to go back to the mass of details I have to learn !
Also Sam made me laugh !
Thank you Nani! That is really great encouragement, and exactly my hope with my videos.
Wonderful video as always! Thanks so much! Pretty scary stuff.
Thank you! this video was so very helpful, explained in a way I could understand :)
The word shock is used many times in Pharmacology books, these lectures of yours have simplified alot of stuff
Thank you so much for the video!
Brilliant. Very useful to me as a nurse
Amazing video for a nursing student.
very nice explanation thankuuuu so much
You’re awesome! I wish all my professors were as great as you. 😍
Amazing presentation!
Thank you so much)))
Very excellant ,u save my life with problem to understand septic shock really thank you
Most amazing presentation
Excellent
Wow great video!
Amazing presentation
Excellent information
Too good explain
Thank you
Thank you good job girl
great video Ma'am . little request could u make more videos on the diseases of the heart . they are really helpful for clinical skills course in physician assistanship school
you're amazing 🙂
please upload more videos
It seems to me that shock caused by bacteria is only possible if the immune system has been suppressed with drugs and letting the bacteria proliferate, then it wakes up after a missed dose or interval? If the system was able to mount such a massive response when the bacteria are everywhere already, it could have mounted a response much earlier.
This paper seems to suggest that it is actually an underactive immune system that leads to sepsis, not the other way round. The 'cytokine storm' is then simply the weak immune response to the infection but now all over the body because the infection has spread everywhere.
Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach. 2013 Lancet
Mam can you make video on evolution of human and how life originated on earth and various theories?
Thanks for the comment and request but my upcoming videos will be focused on microbiology and anatomy & physiology. Eventually I will get to General Biology content! :-)
yu have really broken down the it..... i never understood my lecturer was saying in class
❤
I think CO will increase in septic shock and we will have warm extremities.
If CO decrease it’s bad sign that shock have been developed before couple of hour
Ty for perfect explantation.
Dr. Marik's clinic in East Virginia teaching hospital receives patients from the hospital and is able to save 95% + with his new protocol of intravenous vitamin C and steroids with Thiamine. Please research as this will change the #1 expense (and misery with all of the amputations) of hospitals. I am shocked as every sepsis group I encounter never mention it!
IF you want to love medecine see Mrs SUSANNA
❤🎉
Your information Is good explanation is also good but plz make your video little bit faster your explanation is very slow and and bit waiting time
Ebola can cause this