Innate Immune Defenses

www.sciencewithsusanna.com has diagrams, notes, and practice questions.
Physical/External barriers, Chemical/Internal Defenses, and various leukocytes form the innate immune defenses. Unbroken skin and mucous membranes are key to preventing pathogen entry. Oil, sweat, and body secretions (tears, saliva, vaginal secretions, and wastes such as urine all have antimicrobial defenses. Oil keeps the skin from cracking and the short-chain fatty acids inhibit microbes. Sweat and tears are both salty and contain lysozyme; salt and lysozyme can inhibit microbe growth. Vaginal secretions and urine are acidic, which inhibits many pathogens. Our mucous membranes produce sticky mucus that traps microbes; ear wax works similarly. Internally, inflammation results in leaky blood vessels that flood a wound or infection site with fluids and white blood cells. Epithelial cells and white blood cells produce a huge variety of antimicrobial peptides and fatty acids. The "Complement system includes over 30 small circulating substances that enhance inflammation and phagocytosis, and come together to form Membrane Attack Complex, which punches holes in pathogen cell membranes. Most white blood cells are part of the innate immune response: neutrophils (the most common circulating white blood cell), basophils, and mast cells produce histamine which triggers inflammation, eosinophils are key in tackling parasitic helminths, and phagocytic antigen-presenting cells display antigens from pathogens and thereby activate and link with the adaptive immune response, which involves T and B cells.

[@RebeccaPurjin1]

New subscriber. Thank you for sharing this video. You have a great way of teaching. Very creative and easy to understand.
5/5 stars! :)

[@lanamac8777]

Can you please be my teacher at WEST LA COLLEGE?!
Thank you for explaining everything so clearly.
Much appreciated.

[@tonym6920]

Spectacular presentation, you are amazing! I wonder how the use of all these anti-bacterial soaps, mouthwashes and such disrupt the bodies natural defense system. We really do take our bodies for granted. Thank you for all your hard work.

[@susannaheinze]

Yes, it's definitely established that too much cleaning of the skin disrupts normal flora and can open the door for fungal and bacterial skin infections, particularly in susceptible individuals. Ironic, isn't it?

[@Easy.Biology.drawings]

@@susannaheinze ا۱

[@user-up3vj9kt3f]

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[@lydiacordero5245]

As I’m reading my book for my next semester class I have found this amazing video!
Thank you.

[@janicejoseph3785]

very good teaching skills

[@eddiedann6472]

Wow!!! So so amazingly well put. Fantastic. God Bless you.😍

[@restinabelly2072]

This is amazingggg thank you you helped me alott

[@idrissaid1204]

The more I study immunology, I find that it is so complex and very high tech. This leads me to wonder, we just can't evolve the way modern science wants us to believe. It simply can't be! Whoever invented this superb immune system, has to be the God so-to-say. There is no other explanation.

[@drenpharmacie9349]

Thank you

[@sarmadkamali2653]

i'm so lucky to find your videos today, and now feeling comfortable with immune system

[@Amyaa-ez8wd]

I love your content but this video was missing the complement systems which is really important and high yield for innate immunology

[@faithbolding]

I was wondering if you had all of these notes you draw on a pdf where I can download and print them off to study

[@Mrsgigimac]

She does have some on her website.. I found this specific one and printed it out to follow along. Here is her website:) www.sciencewithsusanna.com/immune-system

[@doctorhady4065]

Good
Please focus more on cvs

[@susannaheinze]

hemostasis and cardiovascular system are on my list for uploading this quarter! :-)

[@vimalkumarguptavimalkumarg8977]

Make more and more vedio

[@keremtoprak7709]

God bless.

[@annymus4502]

What does “inhibit pathogens” mean?
I’m sorry, I’m learning this on my own.

[@GamesPlay-ho1cg]

Inhibit means stopping from work and pathogen is any disease causing organism.

[@annymus4502]

Games Play
So to make the pathogen stop working basically?

[@GamesPlay-ho1cg]

@@annymus4502 yeahh right . it either sometimes stop it or at least try to stop it .

[@annymus4502]

Games Play
Ok, thanks!

[@douaamoussaid8113]

vote for susanna to be my teacher please

[@sl5279]

Plz upload video on antibody production

[@susannaheinze]

I actually do have a couple videos on antibodies. This page of my website links to them: www.sciencewithsusanna.com/immune-system But here is a link to the video too: th-cam.com/video/kXncWxjVOX4/w-d-xo.html and th-cam.com/video/8yfnxx7fDdI/w-d-xo.html Enjoy!

[@vimalkumarguptavimalkumarg8977]

Give me more and more biology vedio