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- เผยแพร่เมื่อ 2 ธ.ค. 2020
- Mobic or Meloxicam is an NSAID just like Celebrex, ibuprofen and naproxen. Although it is classified as a non-specific inhibitor of the COX enzymes, at typical doses it basically blocks only the COX 2 enzyme. As such, Mobic should avoid many of the gastrointestinal, cardiovascular and thromboitc side effects of those aspirin relatives indiscriminately blocking both of the enzymes.
Mobic is the 38th most frequently prescribed medicine in America with more than 19 million prescriptions written each year. Mobic was patented in 1977 and was granted marketing approval by the FDA in 2000.
Primary indications are osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis. It is available as a tablet - either 7.5 mg or 15 mg - with advice to always begin with 7.5 mg once daily for a sufficient time to judge its impact on the underlying disease and the associated pain. It may be taken with or without food. A relatively new orally disintegrating tablet is available at a premium price for those unable to swallow a pill.
A new intravenous preparation for in office use or in ambulatory settings supposedly provides pain relief for 24 hours. Some recent investigations indicate relief only lasts for the first 18 hours with no better relief than placebo for the final 6 hours. Additionally some evidence indicates both Mobic and Celebrex provide less pain relief than full doses of other NSAIDS.
As with any drug, the side effect profile suggests the smallest practical dose for the shortest period of time. Important toxicity relates to the gastrointestinal system with bleeding, ulceration and perforation. Cardiovascular issues include the potential for heart attack and stroke. These issues occur in all of the NSAIDS in use today although the potential for harm might be lowest with Mobic.
Other problems include kidney injury when prostaglandins are important for maintaining renal blood flow. Especial caution is necessary in the elderly and those with dehydration from vomiting, diarrhea or inadequate fluid intake. Risks further increase with pre-existing renal or liver impairment and in those receiving ACE inhibitors or ARBs for control of blood pressure.
This is the only youtube doc i bother watching. No pandering talk, no quick cuts. Just an expert, a monologue and a continuous take. Please never stop uploading until the day you literally run out of drugs to cover.
why he stops ? hmmm maybe he is busy b.c of covid? idk
@@dariusashouri2439 ye i'm sort of afraid he won't come back. I'm almost through all his videos now and they're just great to listen to no matter the subject drug really.
@@Gufberg maybe or maybe not let the pandemic end. He is doctor idk maybe he is busy to make video , any way i guess we missed one of the best.
the after school special vibe is very calming gotta admit
Looking forward to see new videos. I hope the New Year will be good for you dr Landow.
Man o man, are you Good! Like I've spent the last 6 hours watching your videos Good!
justin timberlake has nothing on this guy
Love the depth of these videos.
He passed away at age 73, on March 11, 2022.
Thank You!
Great job on the channel
The side effects of this drug are absolutely HORRIFYING. My doctor prescribed it for lower back pain. I don't think I'll take it. I'd rather be in pain than have a heart attack, or renal failure.
Works well at 7.5 for osteoarthritis pain.
Excellent
Where are you dear doctor. please dont stop the videos.
Hi Dr. Landow! Could you do a video on Demerol please? Or have you already? Thanks.
Probably the safest NSAID along with Lornoxicam regarding cardiovascular, gastrointestinal and renal aspect. Both Meloxicam and Lornoxicam are pretty much COX-2 selective.
Any way we could see a video on Dietylpropion? It’s comparison to adipex and it’s preference for obesity in patients with anxiety ?
Do a Video on Temlisartan
Hi Dr. Ken, hopefully, you're doing well. Just checking up on you. I haven't seen any videos recently. Vacation is good...take care and thank you.
thank you for your comments...plan to post new videos starting in early March
@@wellnowdoctor5976 good to know you're okay, and, i look forward to watch your educational videos. Thank you.
@@wellnowdoctor5976 very glad you're doing well. Stay safe and healthy!
@@wellnowdoctor5976 glad to hear that you’re doing well
@@wellnowdoctor5976 oh nice to see you doc
Dr. Please, do a video on Pimobendan Aka Levosimendan!!!
Can you do guanfacine? Thanks
Hi I can't find your email so I will ask here: please do a video on prazosin :) your videos are informative and easy to understand
Works great for osteoarthritis inflammation pain. However even at 7.5 mg per day, the gastrointestinal side effects plus the drowsiness/tiredness became too much for me. I have gone off of it and back on a few times. But finally have abandoned it.
I’m curious about Strattera
Hi doc....i like your work.....can you do video on clozapine.....tnx😊
Yes, soon
Chẳng hiểu tiếng Anh,sao kênh không dịch ra tiếng Việt
Mr Landow, will you come back?
thank you...shortly
What happened to this channel? It's been over 3 months since this last video.
soon
I’ve been on 15mg Mobic for over a decade to help with chronic low back pain from DDD (degenerative disc disease). I don’t notice the efficacy unless I stop taking it. It’s not like taking Tylenol or Advil or Aspirin, etc. where the action of those drugs are felt as the body continues to absorb and reach peak effect.
Are you still taking it? I noticed my joints feel much better after I’ve been taking it for about three consecutive days versus skipping a day here and there. thanks.
@@curiousj1287 I still take it each day after dinner. It is a drug that works better when taken consistently.
Are you a dermatologist?
Any good for lower back pain / scoliosis?
Thanks!
thank you for addressing your audience like you’d address your peers
This video talks of pain., when you need pain relief can you forget all this info and believe stupid things to cash in on maximum placebo effect?