Pharmacodynamics for Medical Students

A video primer on pharmacodynamics to enable medical students to understand the basic terminology and be able to interpret receptor binding and dose response curves.
However, if you want to learn just the basic terminology and concepts of pharmacodynamics, without interpretation of drug binding/response curves, see my video 'Pharmacodynamics for Nursing Students'
• Pharmacodynamics for N...

[@atiqahsafawati113]

A very good presentation that can help students to study. Thank you Dr. William :)

[@WilliamKLim]

You are very welcome!

[@zhalikadianah6927]

thank you dr, please do more videos on other topics :)

[@WilliamKLim]

I haven' t had the time to make too many! Check my channel: th-cam.com/users/WilliamKLim

[@gibson_az]

This is the best way to initiate students' thinking. Keep up the good work.👍

[@WilliamKLim]

When coupled with Team Based Learning!

[@poonamagarwal4111]

Sir,plz explain the difference between drug selectivity and specificity

[@WilliamKLim]

Hi Poonam. Specificity is more absolute than selectivity! For example, muscarine is specific for muscarinic cholinergic receptors. It can't activate nicotinic cholinergic receptors. And vice versa for nicotine - it's specific for nicotinic cholinergic receptors only. In contrast, selectivity indicates a preference, but it's not absolute. For example, cardioselective beta blockers preferentially block beta1 receptors. Non-cardioselective beta blockers can also block beta2 receptors in the lungs, causing respiratory side effects. But if you give very high doses of cardioselective beta blockers, they will begin to block beta2 receptors too, like the non-cardioselective beta blockers! So cardioselective drugs has selectivity (but not specificity) for beta1 receptors.

[@inthrathanabalan8537]

I found it to be more interesting and really helpful for me. A new way of technique to learn. Thank you so much dr..

[@WilliamKLim]

Flipped learning is the way to go!

[@khanachan95]

Cannot play mehh

[@WilliamKLim]

Problem with iPad? 😃

[@hafiz4393]

Awesome. Now I don't need to come to the class anymore, jk XD

[@WilliamKLim]

😅

[@tikas2259]

Thank you so much dr!

[@WilliamKLim]

You are welcome!

[@MichalRossouw1994]

great lecture!

[@WilliamKLim]

Thanks for watching!

[@timothyimban6907]

great Work!!!!

[@WilliamKLim]

Thanks

[@apexxxx10]

*Excellent lecture! Opioid receptor example TRAMADOL. My case: TKA or TKR Total Knee Replacement. Revision operation 2018. Now in recovery with pain. Here in Thailand, Oxycodone, OxyContin “Hillbilly Heroin” only for cancer patients. TRAMADOL (weak opioid) is good enough. Also for my Mother in law and her arthritis. My recommendation not more than 50 mg per day with strong coffee no sugar! Bangkok Johnnie CarSanook Media THAILAND*

[@WilliamKLim]

Yes, I have included tramadol and oxycodone in my notes for students. Tramadol and its metabolite has a relatively lower affinity for the opioid receptor but it also works by inhibiting the reuptake of serotonin and noradrenaline. www.who.int/medicines/areas/quality_safety/6_1_Update.pdf

[@apexxxx10]

@@WilliamKLim *Thanks William K. Lim. I’ve recovered from my TKR operations. Now riding a big Harley-Davidson motorcycle*

[@apexxxx10]

@@WilliamKLim *Thanks I’m now riding a Harley-Davidson motorcycle* th-cam.com/video/V2n3QmLF4eQ/w-d-xo.html

[@WilliamKLim]

@@apexxxx10 Ride safe