How Traumatic Brain Injury (TBI) Affects Brain Cells - New Research Could Lead to New Treatments
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- เผยแพร่เมื่อ 25 ส.ค. 2024
- Each year about 1.5 million people in the U.S. survive a traumatic brain injury due to a fall, car accident, or a sports injury, which can cause immediate and long-term disability, and neurodegenerative diseases, such as Alzheimer's Disease.
University of Maryland School of Medicine (UMSOM) researchers wanted to better understand what happens in the brain during injury, so they conducted a study in mice to determine how different types of brain cells in mice react to severe trauma. The recently published results could lead to new treatments.
The University of Maryland School of Medicine serves as the anchor for a large academic health center which aims to provide the best medical education, conduct the most innovative biomedical research and provide the best patient care and community service to Maryland and beyond.
#traumaticbraininjury
#neuroscience
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At 21 I hit my head hard. 45 lbs intracranial pressure. Took years before I could read a page in less than 15 minutes. Mid twenties I fell into the machine shop industry. People would get in my face and scream at me when I asked them to repeat instructions two or three times as I struggled to process information. Now I'm 52. I do my job well. People come to me to solve problems. But I still struggle. It's like traveling in my own lane, at my own pace. To merge with the traffic has been too difficult. I live this life as best as I can for myself.
sorry to hear sir
You are a hero in my eyes
@@inelics there were SOME people who could understand I was struggling with an injury that you can't see. No scars. The best advice I got was from a Marine. He said, "Embrace the suck. Ride the wave, make adjustments, move forward".
@@jonkas4542when did u recover from it?
Did you get concussion or was it just a hit.
Had a TBI, 2 Skull Fractures and In A Coma for 6 weeks and 3 days at Baylor Hospital Dallas Texas in 1974.
I'm 60 years old and suffer from GAD, Panic Attacks, Depression, PTSD, Total Memory Loss Prior To Wreak, Headaches Everyday unless I take my Headache Medicine From Neurologist and Paralysis on my left side for 13.5 mths.
I've struggled with my life ups and downs since the wreck.
Where I was hit by a DRUNK DRIVER ON BIKE AND MY BODY WAS UNDER HER CAR FOR 500 FT.
MY BODY LOGGED BETWEEN UNDER CAR AND MY BICYCLE.
HAD BLEEDING FROM MY LEFT EAR, MY NOSE AND MOUTH.
HAVE ANY QUESTIONS ANYONE.
I'D BE HAPPY TO HELP IF I CAN...
GOD BLESS YOU ALL
VEE...
Living with brain damage is a real suffering course because there is no escape, not even a moment's respite. It follows you everywhere like a shadow, even in your dreams where it takes the form of bizarre personifications and strange, broken landscapes.
Yup. It's like being a nomad hitching a ride on spaceship Earth and feeling a million miles away from everyone around.
How did u get this damage and how long does it take u to completely recover?
yes
@@grandfarter3855You don't recover fully from a brain damage. Once your brain cells are gone, they are gone. Sure the brain can work harder and rewire itself but it can't keep that up forever so you end up with increase risk of dementia and other brain disorders.
@@grandfarter3855my father had a brain bleed and they are blaming the blood thinners he took in the ER. Who really knows right? The CT scan may have missed the bleed in the ER, it could have been quite possible it was a slow bleed at home due to a stroke or an injury to his head? I’m quite baffled myself and heartbroken. Thank God there is a God who knows all of these answers. The one thing I need to know if the magnificent love we had for each other. Rest in peace Dad.
I had brain injury and concussion three years ago and feeling it’s improving every day
They'd love me. I've had 10 concussions, 3 skull fractures and knocked unconscious 5 times. 3 years ago I had a stroke to further compound the situation. Memory issues, depression, mood swings, anger issues, balance problems, concentration and learning problems.
How do you cope with this?
@@davidbadihi3915 Very difficult and not very well. On a few meds which help but I don't relate well with people and it's hard to focus anymore.
Hi my wife fell on and landed on the back of her head she had a brain bleed it took them 30 minutes to drain the blood from her head .When i rushed her to the hospital she heard the nurses so she was trying to push the nurses off of her and when they tried to lay her down she was sitting up trying to resist the nurse but she wasn’t talking or opening her eyes thats when i rushed her.She started opening her eyes a hour after the surgery is she going to make a fast recovery
@@brianthompson1137 I'd say it's likely since they got it rather quick. The brain is a weird thing and not everybody reacts the same to TBI. I wish her and you the best.
I have a tbi… my eyes shake during the day sometimes and gotta concentrate to see strait tbi really sucks… brain tingles are normal that’s what I call it… def can’t think sometimes and depression episodes along with memory loss feels like things sometimes are spaced out it’s not a fun problem to deal with but for ten years now I’ve dealt with it… I feel for ya tho
I had my severe tbi when i was 20 from mva, 35.5yrs ago. Frontal & temporal lobe injury; glasgow 5 on presentation; up to 7 within 24hrs. 3wks coma, chronic mental, pysch, physical pain. I've learned to walk, talk, move, think, interact, go back to school, graduate college, work full time, wife, kids, house... pressure, stress, anger, etc... keep going a million mph... lose wife, house, kids, severe depression, anxiety, hate work, life... i've always felt that i probably have a greater chance of dementia/alzheim as i age... in a sense i've accomplished a significant amount considering the place i came from, but i couldn't manage to maintain it... it all got too much and i ended up losing it... was it worth my working so hard??? i'm near the end of the show (will be 56yrs old) and wonder how much more i can go on... i'd like to eventually donate my brain to research
Don’t give up whatever you do don’t give up!!!
Not crying because this is me now n pushing everyone one way n the angry ffffffffkkk that will kill u by itself…
I was in a motor vehicle accident in 2005 at the age of 20 and collapsed the whole right side of my brain. I have struggled with memory issues along with anxiety and severe depression ever since. I have worked the whole time since the accident and my anxiety and seizures have just gotten to bad and i have 38 of the 40 credits needed as well as 20 years of medical records and they still are denying me. I am awaiting my appeal now and can't find an attorney because i filed everything myself. When i see the judge it will have been almost 30 months.
Hang in there buddy.. wish you all the best.
Hi, I sympathize with your experience. I learned that some states (if you are in the US) simply don't grant disability unless you require care to live at all. Florida is one of those states. I too had substantial proof and was denied 3 times because I had filed myself. Meanwhile I completely quit working because I was pink slipped the whole year, I got evaluated for learning disability and the whole lot like working memory and processing speed among many other things and was diagnosed 3 different times as having significant impairment that could not be accomodated on a job and would never improve but only worsen. I had the same judge every time but finally got a charity lawyer through the last one of the 3 the homeless shelters I was in for 2 1/2 years. We got denied on his first defense and requested a state appointed medical expert, turned out worked as a counselor in a women's prison. We were sure we would lose again but because he was curious why I had the same challenges that women inmates had but hadn't ended up in prison likethey did, he read my nearly 3” thick medical record, evaluations, work history and steadfastly endured the judge repeatedly asking him intimidatingly Who pays your salary? To which he answered The State. He layed out to the judge that there were no jobs that would repeatedly retrain me due to memory impairment or spot me indefinitely due to learning disabilities or tolerate the number of days I'd miswork due to depression, anxiety, headaches, body malfunctions, etc.. And she was about to insist that I go to workforce program and get a job with a spotter and he interrupted her saying, It's not just this issue or that issue, she suffers from all of them. She cannot work. There are no jobs that she can perform well enough to hold. The judge was mad. But I got disability that day. It's important to 1) have some kind of attorney 2) get evaluated 3) not be working for as close to 6 months as you can get. Get on AND, tell your doctor you can't perform "any type of job anymore", you are mentally/physically/emotionally maxed out 4) request a medical expert 5) Appeal as often as you're allowed because if you start over, you will lose entitlement to the years of backpay the state would have given you for your previous denials. Always Appeal. 6) don't go into your hearings dressed ss best as you're able, instead go in looking your usual... skipped shower, tied back hair, achy, tired usual unwell self. You don't want to give the judge mixed messages. Look the way you say you feel most of the time. Don't be ashamed to say things like; I dkip meals or over eat, I only shower twice a month due to my fatigue, I have difficulty organizing and cleaning my home, I need help, I forget and burn my meals, foget and miss my appointments, cry often... these things are recorded and evaluated on your and the state's behalves. If your identity and presence doesn't match your claims and records, they deam it inconsistent and deny you disability. But regardless, if you live in a state that doesn't regard any disability but totally dependent on someone else for survival.. you simply not win there. I might look into relocating to a more sympathetic state. Even so, SSI (not enough work history to have SSDI saved up from earnings) is always harder to get than SSDI (awarded when one has accumulated the Social Security Disability INSURANSE savings from years and years of paychecks). Various state charitable/organizations and Human Services, and the like can suggest/direct you to free/sliding scale legal entities like Legal Services in your area. I went to a learning University to get my first learning disability evaluation. I wasn't working so I stated I was indigent and my fees were waived. Go to primary care doctors, request specialist for your specific issues and keep up-to-date records of your issues/symptoms progressing. SSI considers recent documentation as the basis for granting on current disabilities, and only if you cannot perform duties on any type of job for longer than typical job probationary hiring period (aprox. 90 days - 6 mons.). Holding any type of job is very disqualify to them. Your emotional/mental health state is considered as valid as physical health so if you have qualifying mental health issues from your TBI as most do, then let that work for you. Don't keep telling them what we've learned to have to say... I'm doing my best, I'm fine, I'll try... learn to tell the truth ee get rejected for saying to the average person... I'm failing, I have nothing more I can give it, I'm too depressed or fatigued or mentally exhausted to try anymore, I just can't anymore. Believe me, that is what they listen to when everyone else rejects it from you. Say the truth and don't stop saying it. Therapy can be a great place to document all that you go through not just mentally and emotionally but also physically and can document your experiences with good doctors/specialists and bad ones who gaslight you. You can do this much. If you're disabled enough and can still understand this, you can do this much... and you really, really need to before your executive functioning stars failing like mine has and you really need a 24hr babysitter like I do. Get it done before you aren't able to at all. Show the juge what you are like on your worst day, let that help them understand the way it is MOST of the time and document how it has progressed recently. I wish someone had helped me. I had to figure it out myself, no professionals would explain it... I think even they didn't know. I wish you success ❤️ I'm sorry for all the hardship you're suffering. I started my efforts in 2011. I got my probono charity attorney in 2014. I got disability in 2018. I got my BI Waiver in 2020. I'm on permanent disability now, 2024. I was denied 4 times, first 3 I didn't appeal, 4th and 5th I had charitable probono attorney, we lost the 4th and won the 5th trial. I applied and still live in a sympathetic Midwestern state. You won't be forgotten by me.
I survived 3 nuclear bombs while having brain damage, got shot, got electrocuted, got burned and ran over 12 times by a drunk driver. Now i lost all my limbs and is still walking to this day.
I had a TBI when I was 3, I’m 31 now. Would love to see a head scan & talk to a specialist.
What happened?
I hadn't a tbi when I was 3,I'm not 31 now.wouldnt love to see a head scan and talk to a specialist
In someone tried to steal my car and punch me really hard. And I fell backward in a parking lot onto the cement. And my head cracked open. I lost almost all my blood and I almost died.
But had surgery end. Recovered quite nicely. I hope no long term effects now
I'm sorry but I'm seeing some signs just by reading your post
One year for me since my TBI last May ‘23 I was 24. I was in a coma fully brain dead for 2 months craniotomy then cranioplasty 4 months later 40% of my skull is PEEK (thermodynamic plastic). I’ve been back in work since January and the only side effect I cant kick is the tiredness and anxiety
Brad May I plz ask you a question??
@@donnacurtis6425 yea what’s up
When I was 19 I hit my head in a car wreck and was in acoma for a month. I woke up blind in one eye no sense of smell and the front of my skull was removed. Now I barely remember anything and nothing is the same. And now I'm 30.
Eyesight ever recover??
When I got hit on the head with barbbell, I don't know if I had concussion or not because I didn't passed out or vomit instead I my head bleed so much. For the first months I had PTSD symtoms and very painful headeache on the area I got hit the most which is the right side. the very prominent effects of my head injury is I got severe headeache everyday, eventually the headeache reduced to a few time a month and now I only got that headeache when I got stressed.
The least prominent but very noticeable to me is I can't get focused like I used to be. I got diagnosed as an autistic kid when I was 2 or 3 years old, when it came to school assignments and chores I would always do it one time and I used to have social anxiety. After I got that head injury, I neglect my college assignments and chores and I do it when it was near the deadline or if really need it to. I tried to get assignments done with music for adhd people and it only helped me for the first few times, I tried cigarette same case, I ended up focus enhancing drugs from drug store but still the same case. I would say this effect of my head injury stil persist even after 3 years, I would like to get diagnosed for ADHD beause of the similar symtoms. I don't know if this effect was also because mental trauma I had after that head injury. Well I guess I just need to wait it up
😕
I had a heavy object fall on the back of my head thanks to an autistic coworker. I hope it wasn't too bad as I wanted to go back to college. I had vomiting and reoccurring headaches. Also have a headache when I'm stressed or when my head is exposed to extreme temps. I'd say we should visit a doctor. Not like they can do anything bec once your brain is damaged, it's done. No cure for now. But hey, we both need closure so we can tailor our life around it. No more engineering degree and take, I dunno, janitorial degree. Fck life.
I fell off a flat roof when I was 6. Hit concrete on my forehead. Cut my head open in two places. It was in 1967. Just sewed me up and parents took me home. Ace bandage wrapped around my head. The worst headache I ever had. Couldn’t learn certain things. Had a really bad temper too. Be never been the same unfortunately. Self taught guitar because I cannot comprehend learning music. I learn things but over time it’s like I never did. Went to college to study Golf course and Landscape technology. Life has been difficult but I’ve managed to survive lol. I believe in our Creator very much and that keeps me grounded. I feel better these days because this world at this time has gone absolutely nuts. I’m now 63. I only had one migraine in my life and have never actually had a headache since.
You're doing great! Stay positive
A few bad concussion in my life mixed with longcovid in 2020 and I am haveing a lot of trouble. Its difficult to simply make dinner or remember how to work with a power tool. ❤
At 11 years old I had a pony kick me in the head and folded back a piece of skull about 2 inches in diameter on my right temple. I survived it and even got to look into my head with myoms compact mirror before they closed and stitched it up..
Then in about 2017 I was working on my porch/deck and had stood up a 12 foot 4x4 and then forgot about it and I walked about 5 feet away to dig a hole for another post. While I was digging the post I had stood up fell over and knocked me to the ground. It caught the rest right side of my head giving me what I know now as a severe concussion. My wife and I lived by ourselves and we're pretty independent so when this happened she got the garden hose and helped me to wash the blood off my head and finally got it to stop bleeding. The cut was about 7 inches long and she wanted to take me into the hospital but seeing as I was standing and talking to her I said that we would just bandage it up and I had long hair so I had her tie it together like stitches and after a bit I finished digging the hole and nailing up that freaking 4x4 then went to take a shower because I still had quite a bit of blood on me. When I got into the shower I tried to wash out the cut and when the water hit in the cut I couldn't remember anything but she found me kneeling in the shower just rocking back and forth and she helped me snap out of it and got me standing again. It healed with the help of some herbal treatment that I made myself at the time with mullein but now years later I think I'm having issues because of it.
4-5 years after this I was watching TV and I can't tell you what show it was but all of a sudden I had tears streaming down my face! I shouted at her and she came running in to see what was wrong and I remember the look she gave me because I rarely saw that look of fear and confusion. She asked what happened and I told her that I didn't know,! I just started crying! This time, not knowing what the issue was I agreed to go see the doc.
When I did and he asked me if I'd hit my head or something and I told him about it and he felt it he got all pissed off and said that I should have went in and had it looked at then. He was used to us and knew we generally doctored ourselves and agreed that many times that was a good thing but explained how this should not have been one of those times and that perhaps this caused my tears because of pressure but said that nothing could be done about it since it was already healed solid now.
Know I have shortness of breath issues and the years happen a couple of times a week and I get these tense moments which I guess could be considered panic attacks yet no reason for any panic.
I'm wondering if this breathing problem could be related to that and if anyone else has had this issue.
I don't as far as I know have any type of personality changes but she passed away and I'm kind of a loner now so maybe I just don't see it. I can talk to people all day when they're around but when they leave I really don't miss them and can spend several weeks alone literally enjoying the MY TIME! LOL
But I'm trying to simply find out if this could be the cause of my breathing issue because I've been to the doctor many times now and just gave up and am using herbals to treat a possible lung infection with no real success but I had no success )o
That’s a gnarly story man, keep your head up, you’re a warrior. I use to suffer from panic attacks and depression, now just depression but if it is just panic attacks and not like anything physical, you just got stop over thinking and try to relax.. the brain is a strange thing if u panic it’s gna panic. Stay strong.. & about the socializing I think you’re like me we are just introverted , but remember being that isn’t bad its just part of our personality.
I'm glad we're learning these things, but I'm starting to feel bad for the mice
🐁 🧪
i sustained my tbi 4 years ago and i am afraid of future issues
I'm 14 years post TBI and still having Executive Disfunction. Still seeing specialist for coping mechanisms (speech, OT) but all brain injuries are different in terms of degrees of symptoms.
@@WahlVids my most difficult symptoms are my left leg and left arm numbness which is challenging when I play my music instrument. My memory is also challenged severely because I can’t recall a lot since sustaining my tbi
Look into palmitoylethanolamide and perhaps specialized pro resolving mediators.
i have 4 year with my tbi and since first day with tbi
i have depresion anxiety alucinations anger personaly changed and more things is a hell live with that all days are diferents and i never get peace sometimes i feel only drinking beer i going to get peace but i won t i had 14 year no alchol and anything
always i fought in two weeks or two month everthing disappear but not now is 4 yeae and everthing is worses
@@revelacion3241 I HAVE CHANGED for the worse...my wife filed for divorce because we dont have any kids but she raises me kike i am a kid now because my memory issues.
Multiple car wrecks , hit by a car on foot , hit on the head by other objects . Severe head pain , nausea, vomiting . CT’s left and right . Still waiting on the Neuro Dr
Sometimes it doesn't go away last a lifetime
As a kid i would purposly slap my head multiple times with my palm. For some reason is caused problems. Because i did it all time, but now i completly changed as a person. Now i always feels this sensation on my head that feels reslly weird. Its like my body is swimming in air. And i lost personality and evreything. Now people and all my old friends are lost because i can work like a being or anything. Feel emotion or yk normal daily activites and thinking and all that its hell
Fasting, walking, red/infrared light got about 70% back after TBI hit by car.
Hope Faker watches this after that GenG vs T1 match
I also had spinal fliid leaking out of my nose when I tipped my head forward. But for many many many years couldn't verbalize anything I was going thru but the present moment.
I ve had misdiagnosed rightt leg extension and curls and calf raisrs.I can t run,skip, jog,jump.. I have problems walking and hobbling.I also have problems with lifting and carrying groceries.
That one boxer died after boxin he still kept punching random stuff while his brain ain’t functioning 😢
My BTI is already 11 years from my accident the injured part is in my right part of the brain, according to my neurologist doctor a white spotted been seen in my MRI he said thats a blood cut been healed but the connection or function is no longer normal, he have a medicine recommended it's "COLINERVE" 500mlgrm I remember 😅 first it's 1,000mlgrm 😊. But now it's already 11 yrs. My left hand still can't forced well the strength and really the problem of moving normal I can't close open in normal, holding some things and counting on my left hand. Help me/ guide me please doctor. Thank you 😊
Thank you. Can big left frontal lobe meningioma cause TBI
After reading the comments section, I never had a head injury. However I respect the helmet law all if a sudden. I am 53 and did all BMX stunts and riding without a helmet because I couldn't afford one. Now I respect the helmet law, and I always have my kids wear a helmet.
Thank you.
I was 4 years old. My grandmother was driving somewhere... but I don't know why or where. Maybe just to get out. But any ways we got T-boned on a four lane road right behind my sisters school while she was still in school. I was sat in the the direct spot the truck hit
I had bleeding on the brain for 160 hours. I haven't felt right since that
Do you mind if I ask you what happened? Thank you.
I was seven years of age when I fractured my skull - not a depressed fracture but enough to keep me in intensive care for a while. I don't really have a before and after the incident awareness that everyone else does. But I can see that emotional control is difficult. My short-term memory is affected, and I suffer from Persistent Depressive Disorder which is treated with pharmaceuticals. I have an ambitious goal to live an ordinary life. I am lucky to be in an excellent marriage, I have good contact with my adult children, I am studying again at uni, I have a few good friends and I have worked consistently for twenty years in roles that require some cognitive effort. But...I cannot convince my family of my life success. I am sure everyone on this site can relate!!
Good video
Don't work for me
The question then is how does one promote autophagy? I know intermittent fasting is a thing. Vitamin D?
does head movement brain damage like in shadowboxing?
Don't do it anymore. Just stop. Get a safer sport or workout.
Don't u wanna test on someone who has worked with the natives to make are system better I let myself get hit for reasons like I was getting ready for the world ,I was training to become a hip hop artist that went through the struggles of protest an today I stand with the people not being fairly treatment when u break ur arm or even tear muscle or ware muscle or disturb any part of ur body it will affect ur brain ur spine sends the message up to ur brain when ur spine an ur everywhere is hurting u need something for the pain an in my experience drinking liquor an smoking weed isn't going to work for me this time I'd love to help the people just in coincidence the people who need life saver medicine need it thank you
That's good
My classmate slipped on the floor and hit his head very hard on the wall and I saw his head bleeding and his skull was exposed and me and my classmate we called his dad so his dad can take him to the hospital and stitch it.
You should have called 911
Thank you for your care and devotion 🧠👩🌾🌸
The same thing happened to me but how is your friend doing now! My doctors didn't do any tests for me they just asked if I vomited or lost consciousness I said no and they stitched my forgead and told me to go.
Nice
Actually I am thinking that I had suffer or not many times I had hit my head with something hard object and you know you know you know my actually my friends were very very crazy b they usually hit the brain just for a fun but now have knowledge and I encourage not to do that..
When I was eight I did a bicycle Kick and hit my head
Consider Mg Threonate, Palmitoylethanolamide, DHA, Pycnogenol, Specialized Pro Resolving Mediators.
I am interested in your answer...did you or someone you know have a TBI and these things helped?
@@MaryAbbyLind put tbi and each one of them in a search or find my s u b s t a c k
@@MaryAbbyLind The algo has shut this down. On edit to add: Google any of them and NIH. You will get your answers.
That way my room is messy I had a concussion?! I’m wondering if my lifestyle is the reason to my concussion.
I think so, I had a tbi in a car accident 2 years ago and i have a messy room as well.
Same I'm a bare knuckle boxer like fight club except more honor an love don't get me wrong tho getting ur shit pumbled is never fun tho especially with violent people all in love yeah know cousins friends consensual fighters but what we did as kids is starting to mess with me badly an sometimes u might mess up so u gotta rise the lighting an they could hold u under an make u get hurt every year or they could hurt you really badly then I got the shit kicked out of me an my head stomped early an there lots of injurys between then a now last one being hit by a car an one before punched in the head by a huge person more receiving punishments for things as I did what I was doing or little ones through the years like my eldest cousins would have my little cousins to hurt me cause my grandfather knows Barry an berry would know Darcy an Darcy berry would tell Darcy drayin hurt someone in our community not understanding we have consensual fights an more than that community building look at me everything I'm doing u can't say that what ive chosen to help this community I never hurt anyone have u ever got hit by a weak kid it's like a fever dream had sex with a dream where you can't punch hard an sometimes it's be that matter that my cousins were stronger I just wanted to see how they would defend themselves an holsome stuff for native bros
@@drayincommandadw544 Yooooo what are you saying use full stops and commas bro
Look up Executive Disfunction. That's exactly what I struggle with daily as a result from TBI
Search sapien med brain regeneration
Why don't doctor listen to there patients and just say physical therapy
Watch channel 4 news on Traumatic Brain Injuries
On TH-cam
What they have now discovered about Traumatic Brain Injuries from the beginning and through our life for those who have been effected by
TBI, Concussions and Comatose if it last longer than a few days as mine did the long term effects are now discovered to be TETRIMENTAL FOR SOME NOT EVERYONE BUT THE MAJORITY OF US.
Walk it off. Your body will regenerate.
Paraplegic? Nah, walk it off lol. Smh.
Naw man this shit hurts and might need surgery there is no full recovery
Me brain head
Oh heck no, if anything he took more care of me the I did him. Honestly I think he (my father) is still alive but was upset over the advertisements for annuities 🍔🌭🍕