Man, I'm still going through detox therapy from benzos. They are no joke. It ruined my life, including my memory. I get constant muscle twitches, overwhelming anxiety, etc. Pls be safe
i’m a 3rd year chem undergrad working in an organometallics lab and, a few years ago, i would’ve never imagined i’d understand what’s happening in this video. chemistry is so cool :)
@@blueredacted when anything peaks someones interest its amazing what we can learn and how fast we learn I hated being taught in school but Im 41 yo and learning about these things nowadays its not as hard as I remember it being in school
Ppl like you are why the knowledge is so hard to find 🤦 You should work on grammar before attempting any advanced science, maybe get back in the yard with the dogs, cause dis right her is grown man stuff kiddo 😎 quit making this community look like neanderthals, the pot community is the same way, it would be legal everywhere by now if you didn't have people portraying Stoner hippie fall asleep behind the wheel no job dirty types, just bringing us all down
Nile red got me hooked on all this crazy shit 😭fuck all this tho gotta get that legal money someone down the road from me blew there whole house up from cooking that shhh
i came across flunitrazolam a couple years ago, and notices it helped me sleep pretty well, so i used it for around 2 weeks until i ran out. i couldnt sleep at all afterwards for days and actually suffered a grand mal seizure, this stuff is no joke
Did you have kindling due to any past benzodiazepine abuse? There are many reports of flunitrazolam causing seizures with very little use and way more frequently than other benzos. Never done flunitrazolam but nitrazolam is lovely. Very similar to etizolam but has a hypnotic edge to it.
@@McFwoupson This is because flunitrazolam is such a potent benzo that even someone without any previous benzo use can have seizures upon cessation. This is getting to the point where these are the kinds of meds that SHOULD NOT be available to humans other than to study them and use for large animals.
@@alexraubenheimer5815 its no joke benzo and alcohol withdrawal are the only two things that can actually kill just from withdrawal. Everything else will make you feel like you're gonna die but won't actually kill you. With stuff that acts on gaba receptors it can cause strokes and brain bleeds
@@plantationsecurity naw those will still kill you if you quit cold turkey, happen to my cousin he was prescribed a bunch of Klonopins and he had a grand mal seizure and died.
I take Lorazepam (Ativan) for panic disorder, agoraphobia, general anxiety disorder and, social anxiety disorder. It literally saved me. It’s a miracle drug but I can 1000% see why it’s so addictive. All of your problems, physical and mental just melt away as soon as it kicks in. It’s like floating on a cloud.
I have a prescription to ativan as well. It makes anxiety way worse in the long run. I have piles of it now because I stopped taking it. Taking them only compounds the problem instead of solving the reason you have anxiety in the first place. Anxiety is a normal part of life, better to deal with it head on. You will find out sooner or later, one way or another. The doctor wants you on drugs because it's a business not because it will fix you. It might help in the moment but it only compounds the issue. You can't take pills forever, sooner or later your world will implode.
There is 2 plants still very obscure to the modern world that have like chemicals within them except long term use will not lead to addiction or seizures that could end one's existence if they stopped cold turkey repeat, they do not do such unlike the world of pharms choices I have had to take such meds for just over 3 decades so far, I know the struggle all too well yet still do not get why those who do not need it want it so bad, perhaps I have taken it for too long, seems like a waste for them to seek.
@@andersjjensen well, you'll have to deal with the consequences of laws, hydrazine can be less so, for you - it can suck for your loved ones though lol
@@Sonicfl00d hydrazine is extremely dangerous - and, if you handle it without knowing and following proper precautions, your loved ones will be mourning you
@@Sonicfl00d I think they are referring to fetotoxicity (fetus mortality) and poorly studied but identified detrimental effects to female reproductive organs.
i did a cook along with this video when it dropped, I tried some of the yellow powder immediately after, and a dab of green for good measure. I've just woken up, its decent tackle. full relaxation and memory loss for 5 days
I've been addicted to probably most of them lol. Long story short: don't. Withdrawal is excruciatingly painful, then you loose the ability to sleep for a few months, and since benzos tend to suppress the REM phases of sleep (which apparently the brain needs), once you finally can sleep again, it's non-stop hyperrealitic nightmares for possibly years while the brain catches up with its lost REM. Everything has a price. Also you will have months or years disappearing from your memory, as if you weren't there. Many people come to their senses in the hospital or in prison, with no idea whatsoever why. Ah, and that's one of the very few classes of drugs with which sudden discontinuation of use can cause death. And tbh even if you don't die you kinda wish you would. It's really really bad beyond words. Careful with this one folks ;)
As long as you don't abuse benzodiazepines, it's going to be fine. The benzodiazepinesawal is definitely worse than opioids and nobody should take benzos for more than a couple months. Most people become dependent when they take them for too long, but they seldom become ADDICTED as there is a huge difference between addiction and dependence.
@@jackofalltrades3378 the problem is taking them everyday for too long. if u use them once or twice a week you will be fine. when it comes to everyday for months is when u run into problems.
@@jackofalltrades3378 TL;DR: Yes. >> Slightly more elaborated reply: ⤵️ yes indeed, you can totally make a distinction between being addicted and beeing dependent, and I'd say being dependent is worse, because even if you want to quit, it's very hard to do so in practice. Compare with cigarettes : I can't remember my source, but iirc nicotine is said to be one of the most addictive substances there are. But it causes no dependence. To me quitting smoking has never been a big problem. Not smoking is not gonna make you shiver and cry on your bed in the dark in total psychosis for weeks, all the while knowing very well that all that pain could go away in a matter of a few minutes if you took "just one more"... Dependence sucks. Addiction to benzos is probably less common than pure dependence indeed, but whatever the substance, if I had the choice, I'd be addicted rather than dependent. Of course in my initial comment I'm talking about the worst case scenario. Because I know from experience (been to (too) many a rehab...) that there are way too many people who are totally unaware of how dreadful benzo dependence is when they start using (probably less true of the audience of this channel but who knows...), so I wanna make it absolutely clear to the uninformed viewers of this video (if any) how horrible benzo dependence (or addiction) can be. Yes you may not become addicted, but if you become addicted you have very little chances of not becoming dependent. And I'd argue that if you're dependent then addiction is just one small step away, because you will want to use all the time, if only to make the pain go away... and preventing the withdrawal symptoms is gonna be your main preoccupation, day and (sleepless) night, the only relief you can think about being benzos. This is not very far from addiction, or *is* addiction, depending on how you define addiction. Lastly, now that I've done my best to discourage benzo use, yes of course there is a proper, safe way to use benzos (ideally prescribed ones). But even some doctors do not know that they are condemning their patients to hell when they are over-prescribing benzos. Like you said, therapeutic (or otherwise...) benzo use should be kept to a couple of weeks max and then probably a few months break. Benzos are like a garrot, they fix the most pressing issue instantly (not bleeding to death), but leave it on for too long and you will loose the limb. With benzos in this analogy the limb would be your brain, and I have it on good authority that it's bad not to have one any longer ;) Lastly, quitting benzos without much pain is perfectly doable too, by slow and rigorous tapering off and, to that purpose, using a benzo with as long of a half life as you can get instead of the one you're dependent on, I've done it a bunch of times in addition to the horrible cold-turkey ones. But you should do that under close medical supervision. Mere willpower is not gonna be enough in many cases. You need a trained someone to help you stay on track with your taper schedule, and to talk with about all the dreadful things which are gonna start popping into your brain randomly and torture you psychologically.
@@jackofalltrades3378sorry just testing if comments work, I wrote a quite long reply and it doesn't display, I wanna see if I'm being shadow banned or something...
@@jackofalltrades3378 yes indeed there is a difference between addicted and dependant, but dependance often triggers addiction and conversely the distinction doesn't seem very relevant to me here anyways. Of course benzos can be used responsibly, and they are very useful, but they are abused a huge lot too, and many patients are totally unaware of what they may face if they become dependent... Benzos are like a garrot to stop an hemorrhagy: excellent, instant resolution of the issue... But the garrot on for too long and you'll lose the limb.
17:55 the look of a chemist who is so done and just wants it to be over, that you just pour DCM straight out the can and get *most* of it into the flask
I think he he snacked a little bit from charge to charge 🤣
หลายเดือนก่อน +91
When you had almost 5g of material before the last step I was thinking 'this guy will have a lifetime supply of benzos' then you get 30mg like a proper total synth chemist.
@@littleskeleton7887lol and forgetting you even took it. at least until your tolerance gets REAL high, then you could be taking massive doses just to feel anything 😂
There are other videos where other chemists make larger batches don't restrict yourself to only TH-cam there's heavy censorship here and unfortunately it's not as free and flowing knowledge as you might think. In general it does not make sense to use your time to make these just order them from the suppliers!
03:00 Lol, you chose your benzo synth based on the effects of said benzo, apparently. That's pretty funny. You'd be a good friend to have after shtf. You could make anything when everything runs out. What a skill.
I could literally learn about this stuff every day for ever. I wish I could have had an opportunity to be exposed to what chemistry is really all about in school. My teacher just made us memorize the periodic table, make poster board versions of it, and balance equations. It all just seemed so abstract unfortunately… Oh well… it’s never too late to learn!
Knowledge for education is completely legal bud, you okay? 🤷 its ppl and comments like yours that draw wayyyyyy unnecessary negative attention, like someone standing over you screaming as you try to get what you need then they wonder why laws are sooooo strict on drugs and holes get closed, loud mouths screaming for attention and likes bro lmfao 😂😂
I spent a whole damn day at work preparing chlordiazepoxide for HPLC analysis and now, once I'm trying to relax this is the first thing I see. I can't catch a bloody break I swear.
A nice trick for producing (fairly) anhydrous ammonium acetate on demand: Prepare a near-saturated solution of wet ammonium acetate in 3:1 acetic anhydride/glacial acetic acid and allow to stand for a day or two. As needed, pipette portions of this solution into a large excess of anhydrous diethyl ether. The ammonium acetate precipitates out over 5-10 minutes at room temperature and can be collected by filtration and washed with ether. Acetic acid and acetic anhydride both have decent solubility in diethyl ether, but ammonium acetate doesn't.
Damn! I am impressed. You have good skills to be able to perform this synthesis. As far as benzos are concerned, they are highly addictive. But they can serve an essential function for minimizing anxiety. If you are prescribed them just make sure you minimize your use, both dosage and frequency. And switch off completely on a periodic basis to try to minimize your dependency. If you use high dosages for a couple of years straight any sudden withdrawal is going to be severely uncomfortable and painful. That's why the best use if you have to at all is for very short term in response to some stressful life event rather than as a daily coping mechanism for dealing with life in general. I am a very hyperactive person with an extremely high metabolism and nervousness. But in addition, growing up I was exposed to very stressful events and situations at a very young age. I became very withdrawn and uncomfortable in any social setting. I was not confident in opening up to other people unless I used an artificial substance to relax myself and reduce my anxiety.
Really cool and educational video, thanks for taking the time to make this. I feel compelled to share that I was a hardcore benzo addict for a few years. It became a real problem, so I checked myself into a detoxification facility and suffered a grand mal seizure despite being on pheno-barbitol protocol. Benzos are killers. Be safe out there and stay the hell away from benzos if you don't need them to be normal.
Or even better pregabalin. Both in their own unique area with effects that no one really understands. They’re pain killers, anxiety help, but also just helps random organs around the body
Thank you for all your efforts, you are different from everyone, I hope you make a video about the synthesis of thelophylline and the synthesis of amoxicillin
Yes in Quebec and Canada Benzo are highly restricted. Clozapam was prescribed for anxiety but 1/4 of an 0.5 mg makes me sleep for 2 to 3 days min. 20 to 60 hrs shelf life. Very potent meds. High anxiety can be treated but they can be a clutch.
Clonazepam or Clonazolam. Which one are you talking about because one is prescribed whilst the other is not. The effects and duration from the dose you described do not align with the prescribed Clonazepam. However the research chemical Clonazolam is extremely potent and very different to the similarly named Clonazepam
I'm on lorazepam, I've been on it for 2 months, tomorrow I'ma ask my doctor if I can get a lower dose to taper off than hopefully start something much easier going and safe like hydroxyzine
Friend of mine fell into the trap of ordering these online for a year or two. Stuff did him no favors, worsened his anxiety, developed panic attacks then seizures from withdrawal
Man I was watching street tips and next thing you know I am dissolving silver in nitric acid , suddenly I have the urge to try this out :) will keep you posted
Yeagh like lifting you're body of the bed with back of youre head and geel of youre ankle ,tight as bendy metal rigid ,but I'd love to know what makes you talk like youre breathing in helium ,it was h ,,,ll
I'm glad this is extremely complicated. Don't mess with benzos ppl. There's other ways to deal with stress and anxiety without detaching from yourself. Getting your mind and body to stabilize even after being prescribed is nothing short of hell.
Hell yeah I've been using LSA (The seeds containing it are completely legal) once or twice a year and yeah they reduce anxiety by making you really think about things
Ok everyone that's complaining about the video. Its very understandable to cite the dangers of benzos, they're no joke.. but he does say at the beginning that this is just for educational purposes and it's a main disclaimer to letting everyone know that this isn't just for anyone to take and use as a drug it's just for chemistry purposes so lighten up
I smoked MJ. No other meds. Zero physical withdrawal. I was surprised to hear the horror stories of Benzo withdrawal as I never experienced them. I do feel sorry for those that do experience them.
@@joshuastead9634 I was on 2 mg at first than a cap of 6 mg a day over the span of 2 and a half months and had over 2 months to get back to normal. there was a week period three weeks after i stopped that I could only sleep for 1 to 2 hours a night and had severe anxiety for 91 hours straight. every minute sucked and my skin felt like it was crawling all the time. would highly recommend lol
Finally someone says the same.. I was prescribed them for 8 years initially 4mg lorazepam in a hospital setting then when I came out transferred to 40mg diazepam (8 yellows a day, eventually adjusted down to 20mg daily (4 yellows) and It was forced against my will to come off them.. Aggressive taper.. was terrified because of everything I'd heard.. I won't say zero withdrawal but now where near as bad as what people said.. Maybe it is because the vast majority of people on them have anxiety disorders so its a demographic that is inclined to suffer ill feeling.. (and I do admit the rebound anxiety once I came off them was very unpleasant and I do believe I should never have been forced off them (but where I was staying for a year I didn't even have access to a proper doctor let alone my mental health team, so it ended up having to be that way.. But rebound anxiety is different from physical withdraws.. Clearly not everybody finds them that addictive
Ive been on clonazepam for a few years now. It works well but the withdrawals have had me near death. I'd love to see a clonazepam synthesis (i already have the info but i won't do it myself)
Or alprazolam synthesis would be cool too. Always been curious how people made it because black market alprazolam is super common where I live and it's cheap, I figure it can't be too hard to make or it would be very expensive
@999life it wouldn't be illegal if done in the right place, but yeah you're right, I'm just curious to see the process I don't intend to ever make these substances myself.
...and health professionals reasonably don't want peopl ODing or becoming addicted to benzos. It's really nasty withdrawing.... As a card carrying tree hugger, I've always felt that some drugs shouldn't be scheduled, but things like etorphine, carfentanyl, etonitazene, clonazolam, etc? Mixed feelings about them.
making the product and publishing a video on the predominant platform demonstrating that you made the product are sort of different. one is easy to hide.
@@stevengill1736lot of people like clonazolam. If it's just in pill form, normal dose, NOT 0.5mg, like they used to do, it's fine. Bad things can happen with overdosed pills or pure benzo powders
I think you should make the benzophenone, as it is not difficult and an important step, although you can even use the simple Friedel-Crafft acylation as well as several other reactions. There are also the partial agonists, that are far safer, but not marketed in the west, except for flumazenil which is used for antagonist (although it is very weakly agonistic).
I have insomnia since I was born. I have genetic dopamine receptors problem, and after neuroleptics and other dopamine blocking substances that are claimed to be " non-addictive" I suffered from RLS in every muscle of my body to the point of biting myself to blood or almost ripping my muscles just to end this hell. Flunitrazepam I tried only once. It was the best sleep of my life. Every day I use doses of benzos, benadryl and heroin that should ( according to wikipedia) kill at least 10 people just to sleep a few hours. Going off quetiapine was about two months of no more than 2 hours of light sleep daily, not much better than morphine detox. Going off benzos isn't nice, but its nothing compared to living with no sleep aid for me.
Sodium oxybate is sometimes prescribed for narcolepsy and insomnia class sleep disorders, it's literally GHB, similar effects to this. GHB isn't too hard to get on its own even without a prescription I'm surprised you haven't just tried that. Or the various animal tranquilizers that are super effective. Xylazine was being put in fent mixes to induce hard sleep, but it causes necrosis when IV, wouldn't recommend except for oral use.
@@Pepesmall ghb is hard to get where I live. gbl is easy, and its metabolised to ghb n the body. After two days I had to take a dose so big, it made me vomit so hard I cried and sweated a puddle. I get very fast tolerance to all gaba related stuff, probably after 7 years of studies which I passed, but I wasn't able to finish the final diplom work because during apendectomy anaesthesiologyst ruptured my lung and trachea due to too high pressure and mythin tissue layers, and it got iftected, I got sepsis gad 20% chance to live, survived, but got depression and ptsd and then after a massive migration of ukrainians I've got scabies from one of them and I can't cure it since few months, I spend thousands of $ every month for substances that are almost sold for free in USA but not here, and every time there is some piece of clothing I forget to sterilise or some weird place they manage to hide in, and they come back. And all of my studies went into nothing, like it never happened. I sacrificed my liver, most of health physical and mental for nothing.
@@Pepesmallghb is highly addictive too tolerance builds extremely fast and duration is short. It’s prescribed for narcolepsy not just because it induces sleep but also due to it affects sleep patterns. This guy may benefit from using ghb once in a while but not daily. Benzos are probably a better choice for treating insomnia.
0:47 I take a strong disagreement with that statement. I've taken benzodiazepines once, and I would not describe it as removing anxiety, a more apt description is that it stops your ability to care about the anxiety, you still feel the anxiety, your brain just doesn't care about it.
I took Valium for a surgical revision that I wasn't sedated for. Usually that sort of thing would cause me to freak out so hard I'd pass out, but the Valium brought me to a normal anxiety level. Just took me down a notch I suppose
well.. you’re not everyone. I used to both take prescription benzos, and abuse them, and illegal benzos, because it essentially turned my anxiety off completely. I used to get bad anxiety after a while from smoking pot, and if I took a bar and smoked, there would be nothing. I had a great time every time. just as an example. The only thing that worked similarly well for me was Gabapentin. SSRI’s make you feel like a zombie. I guess it works in that aspect for its anxiolytic effects, but I didn’t like feeling like an emotionless zombie.
As someone with anxiety, I'm gonna push back hard on the intro. While they solve the feeling of anxiety at first, they have the dual issue of (1) very quickly increasing tolerance and (2) tending to be counter-productive to CBT based techniques for long term change. In particular, they fuck with your memory HARD. Some people aren't too affected, but even therapeutic doses give me a sort of almost blackout "video tape" memory where I can only remember flashes. Benzos absolutely have their use. They work excellently in an inpatient setting, and they even have some great uses for short term effects. But they really are not good for chronic anxiety disorders. They're about as effective as alcohol where mostly they make you stop caring.
gotta keep your plausible deniability as far as accidentally creating any illegal products. assuming he has properly disposed of everything he made in this video, nobody will ever be able to prove that he made something illegal if he somehow did by accident. Can't say the same if you use a university's NMR or mass spectrometer to analyze your products, those test results will be stored somewhere out of your control from which the police can subpoena them.
Designer benzodiazepines completely ruined my life. I attempted to self delete, totalled 4 cars, got 3 duis in one year, lost my wife, my 3 sons, my house, my money and I actaully didn't lose them till after rehab and sobriety. Clonazolam was what got me. Oh and I was facing 15 years in prison thanks to the failed deletion attempt because it was by OD on fent/bromazolam.
Dude just couldn't hold his existential dread. The full resources of our fanciest university behind him, and nobody would slap him together a damn taper?!
I am not sure that i like this trend of everyone getting into psychoactive substances on YT nowadays, but the video itself was very cool to watch as usual.
If I hadn't read chemistry A and B, or trimesters 1 and 2 as some countrys call it, I would have no clue to how to follow what you are doing (Like you just say TLC instead of Thin Lair Chromatography), however this procedure makes me wounder how the hades they did discover benzos in the first place, I mean it's not all that obvious, and who did they test it on to find out the properties of it on humans?
@@creature2479 Yeah, but what compelled a random chemist to do this quite complicated procedure to get to this molecule in the first place? There must have been a pre-thought behind it, you just can't just arrive at this at random.
Usually it starts out by discovering an effect by some plant or animal made chemical, as it gets tested out its structure is identified and then chemists usually fuck around and find out, one way or the other
@@williamabrahamsson2945 prolly some kind of plant material was found by tasting something for characterisation(old chem books have color, crystal shape, smell AND TASTE listed as properties at stuff like mercury and crazy shit like that) that had some kind of effect. then they fucked around with the molecule and found other analouges
Benzos have stopped my heroin addiction just to get into a 10 times worse benzo addiction. Although they ruined everything i still cant hate them just because how good they make you feel
@@AlexanderSchwarz-ck3cx10 year long opiate addict.. the last year before I got clean 2022 I had unlimited farmapram's. Coming off of those and fent even with methadone was pretty rough.
Benzos are fantastic, just as long as you disregard any prescription that would have you take them as a daily medication. When I was prescribed alprazolam i adopted the principle of once a dose is taken it must be fully out of my system (~72-96 hours) before I will allow myself to use it again. Works absolutely perfectly when I need it, at the same dosage i was originally prescribed (.25mg - 2mg depending on why im taking it). Never ran out, never had to ask for increases.
You should bring a natural product back. Your geosmin project went awry in the reductive deoxygenation of the tosyl ester step. Maybe find a work around or even a different molecule altogether?
Clam is too good. Flualp is too. Now days bromazolam is the most accessible. Ugh, been dealing with these things for so long. Haha. Glad I dont use them anymore though.
Yes Ma'am here is something that will barely work at all but costs an arm and a leg. That is why I left Pharmacy and went back to school for many years....UGH....I am now starting a gourmet and medicinal mushroom business in Delaware. Mainly Blue Oyster, Golden Oyster, Reishi, and shiitake mushrooms...There is reputable literature showing high rates of tumor regression from 95 to 100%. Especially Reishi....
I get diazepam, been on them for a long time, 20 years long time, and I have schizophrenia so I don't find it hard to get them when I ask if I'm having a hard time, though, don't stay on them for too long, coming off them is crazy, you can literally feel the juices moving around in your head trying to figure out what to do when you come off them after taking too much for too long. Full scale mental breakdown.
Watching videos like this makes me wish I had a better Chem professor in college. Mine was such a butthead (putting it nicely), I hated his class and didn't learn much.
Man, I'm still going through detox therapy from benzos. They are no joke. It ruined my life, including my memory. I get constant muscle twitches, overwhelming anxiety, etc. Pls be safe
Try DMT.
You need to be on benzodiazepine, it will cure and help you.
Try fentyl
Try carnivore diet
Try CS
i’m a 3rd year chem undergrad working in an organometallics lab and, a few years ago, i would’ve never imagined i’d understand what’s happening in this video. chemistry is so cool :)
What's with the anime photo?
@@sleepyjo9340 what a weird question to ask somebody on the internet lmao
@@sleepyjo9340 is it your first day here?
@@blueredacted when anything peaks someones interest its amazing what we can learn and how fast we learn I hated being taught in school but Im 41 yo and learning about these things nowadays its not as hard as I remember it being in school
So you going to turn out a batch?
WE EDGING THE POLICE WITH THIS ONE🗣️❗️❗️
We commenting the same from all our accounts 🗣️‼️
Ppl like you are why the knowledge is so hard to find 🤦 You should work on grammar before attempting any advanced science, maybe get back in the yard with the dogs, cause dis right her is grown man stuff kiddo 😎 quit making this community look like neanderthals, the pot community is the same way, it would be legal everywhere by now if you didn't have people portraying Stoner hippie fall asleep behind the wheel no job dirty types, just bringing us all down
More like the glazing is real 😂
2 -Hot, 4-SWAT. ❤
They've been goonin on this channel
ladies and gentlemen, it's an honor to be on this watch list with you all‼️
😂😂😂
🫡
Nile red got me hooked on all this crazy shit 😭fuck all this tho gotta get that legal money someone down the road from me blew there whole house up from cooking that shhh
What watch list? Lol. This is the 3rd time I've seen this comment. That can't be good! Lol.
@@sarah-jaynemcdonald2594 the DEA watchlist for suspicious activity involving synthesizing legal, illegal, or grey area drugs and compounds lmfao
I love benzos!!! Literally wake up shaking because of how excited they make me :]
That warms my heart.
That's called with dralees in the mourning haha
Bar tard.
Bar tar*d
Bar T*rd
I've literally never seen a man less afraid of yellow chemistry.
E&F rolling in his cubane shaped grave :c
@@JohnDoe-uo7kb grave or grav-e
Especially that doesn't go kaaa-boom! lol
opium crack
I was literally on my way down here to say this. We have it on good(ish) authority that yellow chemistry is bad.
I subscribed for better yields 💀
yooooooo lol
Lmao
Good luck 😂😂😂
I mean, I'd never!
yes sir!
Hell yeah, Try to stop me DEA 💪
i came across flunitrazolam a couple years ago, and notices it helped me sleep pretty well, so i used it for around 2 weeks until i ran out. i couldnt sleep at all afterwards for days and actually suffered a grand mal seizure, this stuff is no joke
Did you have kindling due to any past benzodiazepine abuse? There are many reports of flunitrazolam causing seizures with very little use and way more frequently than other benzos. Never done flunitrazolam but nitrazolam is lovely. Very similar to etizolam but has a hypnotic edge to it.
@@McFwoupson This is because flunitrazolam is such a potent benzo that even someone without any previous benzo use can have seizures upon cessation. This is getting to the point where these are the kinds of meds that SHOULD NOT be available to humans other than to study them and use for large animals.
Holy shit dude that is SO gnarly, im on 50mg methsdone for an iv opiod addiction but your story makes mine sound like kidergarden
@@alexraubenheimer5815 its no joke benzo and alcohol withdrawal are the only two things that can actually kill just from withdrawal. Everything else will make you feel like you're gonna die but won't actually kill you. With stuff that acts on gaba receptors it can cause strokes and brain bleeds
I want some!
Ngl it made me slightly happy seeing you get a .5% yield after running a column since I lost 94% of my crude material in a column 3 days ago.
Oh the excrutiating pain of recovering 10mg of product from 120mg crude 😭
As a biochemist, I am overjoyed if I get 10mg product from 50g of crude material (biomass). Making pure protein is an inefficient process haha.
@@nerd1000ify lol mine is not that bad since this is my product from 10g start material but alas its like 6-7 steps with mediocre yields
@@jane._.v-y7q that's good expression if you are making a recombinant protein.
It's a miracle that anything at all was recovered. lol
We withdrawing hard from this one 🗣🔥🔥
Wds wnethridmygh hard withi this one
DeAnthonys are smart.
Lol ya if u want to have seizures for life@@plantationsecurity
This vid just cured my anxiety of ever running out. lol
@@plantationsecurity naw those will still kill you if you quit cold turkey, happen to my cousin he was prescribed a bunch of Klonopins and he had a grand mal seizure and died.
holy my man, you are the spearhead of fearless yet responsible, well done chemistry content on youtube
I take Lorazepam (Ativan) for panic disorder, agoraphobia, general anxiety disorder and, social anxiety disorder. It literally saved me. It’s a miracle drug but I can 1000% see why it’s so addictive. All of your problems, physical and mental just melt away as soon as it kicks in. It’s like floating on a cloud.
Lol. "I can see why it's addicting, it makes all your problems go away" sounds like the worst thing ever!!
@@Pepesmall lmaooo it’s just the worst 😂
I have a prescription to ativan as well. It makes anxiety way worse in the long run. I have piles of it now because I stopped taking it. Taking them only compounds the problem instead of solving the reason you have anxiety in the first place. Anxiety is a normal part of life, better to deal with it head on. You will find out sooner or later, one way or another. The doctor wants you on drugs because it's a business not because it will fix you. It might help in the moment but it only compounds the issue. You can't take pills forever, sooner or later your world will implode.
There is 2 plants still very obscure to the modern world that have like chemicals within them except long term use will not lead to addiction or seizures that could end one's existence if they stopped cold turkey repeat, they do not do such unlike the world of pharms choices I have had to take such meds for just over 3 decades so far, I know the struggle all too well yet still do not get why those who do not need it want it so bad, perhaps I have taken it for too long, seems like a waste for them to seek.
Dude if u got piles of it send me some please@@ShaneMclane-PrivateEye
I like how your biggest concern was the lawessons reagent not using hydrazine hydrate,
Yeah, that one had me in stitches too.
@@andersjjensen well, you'll have to deal with the consequences of laws, hydrazine can be less so, for you - it can suck for your loved ones though lol
@@Sonicfl00d hydrazine is extremely dangerous - and, if you handle it without knowing and following proper precautions, your loved ones will be mourning you
@@Sonicfl00d it'll suck till you're dead
@@Sonicfl00d I think they are referring to fetotoxicity (fetus mortality) and poorly studied but identified detrimental effects to female reproductive organs.
i did a cook along with this video when it dropped, I tried some of the yellow powder immediately after, and a dab of green for good measure. I've just woken up, its decent tackle. full relaxation and memory loss for 5 days
Bro what 💀
Lmao if you didn’t wake up with your house completely trashed and random injuries then you’re full of shit
I've been addicted to probably most of them lol. Long story short: don't. Withdrawal is excruciatingly painful, then you loose the ability to sleep for a few months, and since benzos tend to suppress the REM phases of sleep (which apparently the brain needs), once you finally can sleep again, it's non-stop hyperrealitic nightmares for possibly years while the brain catches up with its lost REM. Everything has a price. Also you will have months or years disappearing from your memory, as if you weren't there. Many people come to their senses in the hospital or in prison, with no idea whatsoever why. Ah, and that's one of the very few classes of drugs with which sudden discontinuation of use can cause death. And tbh even if you don't die you kinda wish you would. It's really really bad beyond words. Careful with this one folks ;)
As long as you don't abuse benzodiazepines, it's going to be fine. The benzodiazepinesawal is definitely worse than opioids and nobody should take benzos for more than a couple months. Most people become dependent when they take them for too long, but they seldom become ADDICTED as there is a huge difference between addiction and dependence.
@@jackofalltrades3378 the problem is taking them everyday for too long. if u use them once or twice a week you will be fine. when it comes to everyday for months is when u run into problems.
@@jackofalltrades3378 TL;DR: Yes.
>> Slightly more elaborated reply: ⤵️
yes indeed, you can totally make a distinction between being addicted and beeing dependent, and I'd say being dependent is worse, because even if you want to quit, it's very hard to do so in practice.
Compare with cigarettes : I can't remember my source, but iirc nicotine is said to be one of the most addictive substances there are. But it causes no dependence. To me quitting smoking has never been a big problem. Not smoking is not gonna make you shiver and cry on your bed in the dark in total psychosis for weeks, all the while knowing very well that all that pain could go away in a matter of a few minutes if you took "just one more"... Dependence sucks.
Addiction to benzos is probably less common than pure dependence indeed, but whatever the substance, if I had the choice, I'd be addicted rather than dependent.
Of course in my initial comment I'm talking about the worst case scenario. Because I know from experience (been to (too) many a rehab...) that there are way too many people who are totally unaware of how dreadful benzo dependence is when they start using (probably less true of the audience of this channel but who knows...), so I wanna make it absolutely clear to the uninformed viewers of this video (if any) how horrible benzo dependence (or addiction) can be.
Yes you may not become addicted, but if you become addicted you have very little chances of not becoming dependent. And I'd argue that if you're dependent then addiction is just one small step away, because you will want to use all the time, if only to make the pain go away... and preventing the withdrawal symptoms is gonna be your main preoccupation, day and (sleepless) night, the only relief you can think about being benzos. This is not very far from addiction, or *is* addiction, depending on how you define addiction.
Lastly, now that I've done my best to discourage benzo use, yes of course there is a proper, safe way to use benzos (ideally prescribed ones). But even some doctors do not know that they are condemning their patients to hell when they are over-prescribing benzos.
Like you said, therapeutic (or otherwise...) benzo use should be kept to a couple of weeks max and then probably a few months break.
Benzos are like a garrot, they fix the most pressing issue instantly (not bleeding to death), but leave it on for too long and you will loose the limb. With benzos in this analogy the limb would be your brain, and I have it on good authority that it's bad not to have one any longer ;)
Lastly, quitting benzos without much pain is perfectly doable too, by slow and rigorous tapering off and, to that purpose, using a benzo with as long of a half life as you can get instead of the one you're dependent on, I've done it a bunch of times in addition to the horrible cold-turkey ones. But you should do that under close medical supervision. Mere willpower is not gonna be enough in many cases. You need a trained someone to help you stay on track with your taper schedule, and to talk with about all the dreadful things which are gonna start popping into your brain randomly and torture you psychologically.
@@jackofalltrades3378sorry just testing if comments work, I wrote a quite long reply and it doesn't display, I wanna see if I'm being shadow banned or something...
@@jackofalltrades3378 yes indeed there is a difference between addicted and dependant, but dependance often triggers addiction and conversely the distinction doesn't seem very relevant to me here anyways.
Of course benzos can be used responsibly, and they are very useful, but they are abused a huge lot too, and many patients are totally unaware of what they may face if they become dependent...
Benzos are like a garrot to stop an hemorrhagy: excellent, instant resolution of the issue... But the garrot on for too long and you'll lose the limb.
17:55 the look of a chemist who is so done and just wants it to be over, that you just pour DCM straight out the can and get *most* of it into the flask
Really goes to show how different chemistry is in the lab vs. on paper
I think he he snacked a little bit from charge to charge 🤣
When you had almost 5g of material before the last step I was thinking 'this guy will have a lifetime supply of benzos' then you get 30mg like a proper total synth chemist.
Lmfaooooooooooo
you’d think 5g is a lifetime supply but your tolerance increases so much you’ll be going thru it super fast
@@littleskeleton7887lol and forgetting you even took it. at least until your tolerance gets REAL high, then you could be taking massive doses just to feel anything 😂
There are other videos where other chemists make larger batches don't restrict yourself to only TH-cam there's heavy censorship here and unfortunately it's not as free and flowing knowledge as you might think. In general it does not make sense to use your time to make these just order them from the suppliers!
@@HighHrothgar0 that’s what I do I order online
Finally an chemistry TH-camr that that gives us what we want, pharmaceutic synthesis!!!
03:00 Lol, you chose your benzo synth based on the effects of said benzo, apparently. That's pretty funny. You'd be a good friend to have after shtf. You could make anything when everything runs out. What a skill.
When walking the fine line isn't enough, chemiolis is grinding his skateboard on a knife edge...
I could literally learn about this stuff every day for ever. I wish I could have had an opportunity to be exposed to what chemistry is really all about in school. My teacher just made us memorize the periodic table, make poster board versions of it, and balance equations. It all just seemed so abstract unfortunately… Oh well… it’s never too late to learn!
Bro walks the finest of lines... 😅 jeeezus
Fancy finding you here
almost as fine as a line of coke
@@seraphxxkuraku9361ketamine is better
Knowledge for education is completely legal bud, you okay? 🤷 its ppl and comments like yours that draw wayyyyyy unnecessary negative attention, like someone standing over you screaming as you try to get what you need then they wonder why laws are sooooo strict on drugs and holes get closed, loud mouths screaming for attention and likes bro lmfao 😂😂
@@seraphxxkuraku9361tootski???
I spent a whole damn day at work preparing chlordiazepoxide for HPLC analysis and now, once I'm trying to relax this is the first thing I see. I can't catch a bloody break I swear.
Hahah 💯
I know how you feel.... it's like I cook all day for these ppl and then I get home and I still have to make my own food.....truly madding...
Jordan Peterson knows all about these.
you should get a rotovap and a combiflash
Fr
donate
@@Chemiolis this.
@@Chemiolis😂😂😂😂 only if ya donate to my portable spectrograph fund 😂😂
@@ChemiolisI’m kidding I can’t even afford being broke
Was prescribed 40 mg /day of Valium for the past 12 yrs. Detoxed 60 days ago, still testing positive and feeling pretty bad. But hey I’m sober…Yay.
Yay🎉❤
A nice trick for producing (fairly) anhydrous ammonium acetate on demand: Prepare a near-saturated solution of wet ammonium acetate in 3:1 acetic anhydride/glacial acetic acid and allow to stand for a day or two. As needed, pipette portions of this solution into a large excess of anhydrous diethyl ether. The ammonium acetate precipitates out over 5-10 minutes at room temperature and can be collected by filtration and washed with ether.
Acetic acid and acetic anhydride both have decent solubility in diethyl ether, but ammonium acetate doesn't.
First barbiturates now benzos on main
Chemiolis how do you do it
Damn! I am impressed. You have good skills to be able to perform this synthesis. As far as benzos are concerned, they are highly addictive. But they can serve an essential function for minimizing anxiety. If you are prescribed them just make sure you minimize your use, both dosage and frequency. And switch off completely on a periodic basis to try to minimize your dependency. If you use high dosages for a couple of years straight any sudden withdrawal is going to be severely uncomfortable and painful. That's why the best use if you have to at all is for very short term in response to some stressful life event rather than as a daily coping mechanism for dealing with life in general. I am a very hyperactive person with an extremely high metabolism and nervousness. But in addition, growing up I was exposed to very stressful events and situations at a very young age. I became very withdrawn and uncomfortable in any social setting. I was not confident in opening up to other people unless I used an artificial substance to relax myself and reduce my anxiety.
Deliciously yellow. You know a chemical is good when it has that color
I have 10g of avizifone that is awesome. Rilmaz is next on the list.
Ya, yellow go up or down. ;D
Flunitrazepam when cooked it was a yellow soup. Mixed with Heroin we called it Frankfurter Cocktail.
WE CURIN ANXIETY W THIS ONE 🗣🗣🗣🗣🔥🔥🔥🔥‼️‼️‼️
Or causing it
can't remember what anxiety is anymore. in fact i cannot remember much at all
@@oximedreams3284Let me get summa that
@@oximedreams3284 you beat up my mom last night bruh!
We commenting the same from all our accounts 🗣️‼️
WE'RE FALLING ASLEEP WITH THIS ONE 😴😴😴🔥🔥🔥
Forever.
Really cool and educational video, thanks for taking the time to make this. I feel compelled to share that I was a hardcore benzo addict for a few years. It became a real problem, so I checked myself into a detoxification facility and suffered a grand mal seizure despite being on pheno-barbitol protocol. Benzos are killers. Be safe out there and stay the hell away from benzos if you don't need them to be normal.
Just so my handlers will know that I was brought here by the algorithm
Same
"handlers"
Same
Speaking of gaba receptors, the synthesis of gabapentin looks interesting.
gaba pentin is a trash drvg
Or even better pregabalin. Both in their own unique area with effects that no one really understands. They’re pain killers, anxiety help, but also just helps random organs around the body
@@olliesells8856 Pregabalin is basically two gabapentin molecules attached together eh? Yeah seeing that synthesized would be interesting for sure.
@@olliesells8856another nightmare addiction
Thank you for all your efforts, you are different from everyone, I hope you make a video about the synthesis of thelophylline and the synthesis of amoxicillin
Yeah benzos and street drugs are cool and everything but being able to synthesize your own antibiotics would be priceless
@@joshuaolander201 I'm talking about the fact that we can learn. I think we would benefit from learning how to make antibiotics.
Yes in Quebec and Canada Benzo are highly restricted. Clozapam was prescribed for anxiety but 1/4 of an 0.5 mg makes me sleep for 2 to 3 days min. 20 to 60 hrs shelf life. Very potent meds. High anxiety can be treated but they can be a clutch.
Clonazepam or Clonazolam. Which one are you talking about because one is prescribed whilst the other is not.
The effects and duration from the dose you described do not align with the prescribed Clonazepam. However the research chemical Clonazolam is extremely potent and very different to the similarly named Clonazepam
@@LK-em1bvheck I take 3 0.5mg Klonopin “Clonazepam” a day
Please do a video making 7-Hydroxymitragynine or mitragynine pseudoindoxole
This
Oh god why does this keep popping up lately. I want to buy a gram or powder before it gets banned.
Khat.
Waste of time, just go straight to diamorphine
@@UNcommonSenseAUSfacts
repost
I'm on lorazepam, I've been on it for 2 months, tomorrow I'ma ask my doctor if I can get a lower dose to taper off than hopefully start something much easier going and safe like hydroxyzine
Friend of mine fell into the trap of ordering these online for a year or two. Stuff did him no favors, worsened his anxiety, developed panic attacks then seizures from withdrawal
Where do you order from online
@@mikezombro9809Lizard Labs
Ok this one is insane
Welcome on the DEA watchlist
the DEA is a terrorist organisation
yaa noo, no DEA here
yes, you are safe and don't have to worry about anything
me and officer driller will take care of everything
I already was
Welcome. Your contributions are due every month by the 1st.
I feel blessed to have been able to watch this video before it inevitably gets taken down 🙏
Man I was watching street tips and next thing you know I am dissolving silver in nitric acid , suddenly I have the urge to try this out :) will keep you posted
Benzos can also have pretty awful (and potentially deadly) withdrawal.
Yup, the WDs aren't to be played with so those who decide to use need to remember that these are not your daily driver.
Yeagh like lifting you're body of the bed with back of youre head and geel of youre ankle ,tight as bendy metal rigid ,but I'd love to know what makes you talk like youre breathing in helium ,it was h ,,,ll
Don't forget potentially permanent.
I love being on this watchlist. One of the best communities and I wear it like a badge of honor.
Also that dimorpholinophosphyryl acid chloride is the coolest reagent I have ever seen
I wanna see this man synthesise WF-23. It's a cocaine analogue with 100x the potency and a half life of 3 days.
🤯 is it scheduled?
That sounds psychosis inducing. Stimulants are prone to people redosing. You're getting 0 sleep on that.
Is that half life in the body, or on the shelf?
@@Andrew-pd6ey spoken like someone who's only seen after school specials
A cocaine an analogue this that long-lasting sounds terrible the entire Joy of Coke is the rush of doing it
I love that most home chemists are using at least 1 stonylab item - yours was the graduated cylinder!
💙
I'm glad this is extremely complicated. Don't mess with benzos ppl. There's other ways to deal with stress and anxiety without detaching from yourself.
Getting your mind and body to stabilize even after being prescribed is nothing short of hell.
DMT removed my anxiety. benzos just stop from trying to find or resolve the problem causing the anxiety. Thx for the video.
Hell yeah I've been using LSA (The seeds containing it are completely legal) once or twice a year and yeah they reduce anxiety by making you really think about things
@@creature2479try smoking weed once or twice a year, especially if your doing LSA.
bruh, dmt is trash ,only good for sub 100 iq ppl
oh shit, subscribing you was worth it
Pynazolam is pretty interesting - it actually acts as a serotonin releasing agent much like Methaqualone does.
Flunatrizolam was a great help at times.
Its strength was needed.
The ol’ rectangular life-ruiner
Ok everyone that's complaining about the video. Its very understandable to cite the dangers of benzos, they're no joke.. but he does say at the beginning that this is just for educational purposes and it's a main disclaimer to letting everyone know that this isn't just for anyone to take and use as a drug it's just for chemistry purposes so lighten up
My wife responsibly uses benzos as prescribed by her healthcare professionals for her bipolar disorder. ❤
bot
@@catlolis nah, I was just stoned
@@AB-gf4ue you live in the middle east?
@@catlolis nah, too gay for that
I take them responsibly as prescribed. I found benzos to be the only effective treatment for my anxiety.
I was on a 2-4 mg daily dose for a few years and stopped cold turkey. I experienced ZERO withdrawal symptoms.
Sounds near impossible to me… 🤔 Are you on other heavy medications maybe?
There's literally no way
I smoked MJ. No other meds.
Zero physical withdrawal.
I was surprised to hear the horror stories of Benzo withdrawal as I never experienced them.
I do feel sorry for those that do experience them.
@@joshuastead9634 I was on 2 mg at first than a cap of 6 mg a day over the span of 2 and a half months and had over 2 months to get back to normal. there was a week period three weeks after i stopped that I could only sleep for 1 to 2 hours a night and had severe anxiety for 91 hours straight. every minute sucked and my skin felt like it was crawling all the time.
would highly recommend lol
Finally someone says the same..
I was prescribed them for 8 years
initially 4mg lorazepam in a hospital setting then when I came out transferred to 40mg diazepam (8 yellows a day, eventually adjusted down to 20mg daily (4 yellows)
and It was forced against my will to come off them.. Aggressive taper.. was terrified because of everything I'd heard..
I won't say zero withdrawal but now where near as bad as what people said.. Maybe it is because the vast majority of people on them have anxiety disorders so its a demographic that is inclined to suffer ill feeling.. (and I do admit the rebound anxiety once I came off them was very unpleasant and I do believe I should never have been forced off them (but where I was staying for a year I didn't even have access to a proper doctor let alone my mental health team, so it ended up having to be that way..
But rebound anxiety is different from physical withdraws.. Clearly not everybody finds them that addictive
Next video: Synthesising Prison Time (I Got Caught)
Me too, but it was worth it....however YMMV
The substance is legal.
Instant sub! Love how you just shoot from the hip and substitute reagents 😂 That takes DEEP knowledge!❤
Ive been on clonazepam for a few years now. It works well but the withdrawals have had me near death. I'd love to see a clonazepam synthesis (i already have the info but i won't do it myself)
Or alprazolam synthesis would be cool too. Always been curious how people made it because black market alprazolam is super common where I live and it's cheap, I figure it can't be too hard to make or it would be very expensive
@@nevercertain An alprazolam/clonazepam synthesis on YT would be highly illegal, but you're right in the aspect it would be cool to watch.
@999life it wouldn't be illegal if done in the right place, but yeah you're right, I'm just curious to see the process I don't intend to ever make these substances myself.
@@nevercertainOne of the reasons black market alazopram is so available is because it's often just fentanyl lol
abused clonazepam for years quitting was so impossibly hard. I really wanna know the info on how it's synthesised outta curiosity
That's a lot of work for such a tiny amount.. Wow! 😮💊
its so insane that chemists have to skirt around illegal intermediates in synthesis
Yea big pharma doesn't want us fixing ourselfs
...and health professionals reasonably don't want peopl ODing or becoming addicted to benzos. It's really nasty withdrawing....
As a card carrying tree hugger, I've always felt that some drugs shouldn't be scheduled, but things like etorphine, carfentanyl, etonitazene, clonazolam, etc?
Mixed feelings about them.
@@stevengill1736clonazolam. Yeah sure. Clonazepam? No. It needs to be easier to access.
making the product and publishing a video on the predominant platform demonstrating that you made the product are sort of different. one is easy to hide.
@@stevengill1736lot of people like clonazolam. If it's just in pill form, normal dose, NOT 0.5mg, like they used to do, it's fine. Bad things can happen with overdosed pills or pure benzo powders
I think you should make the benzophenone, as it is not difficult and an important step, although you can even use the simple Friedel-Crafft acylation as well as several other reactions.
There are also the partial agonists, that are far safer, but not marketed in the west, except for flumazenil which is used for antagonist (although it is very weakly agonistic).
I have insomnia since I was born. I have genetic dopamine receptors problem, and after neuroleptics and other dopamine blocking substances that are claimed to be " non-addictive" I suffered from RLS in every muscle of my body to the point of biting myself to blood or almost ripping my muscles just to end this hell.
Flunitrazepam I tried only once. It was the best sleep of my life. Every day I use doses of benzos, benadryl and heroin that should ( according to wikipedia) kill at least 10 people just to sleep a few hours. Going off quetiapine was about two months of no more than 2 hours of light sleep daily, not much better than morphine detox. Going off benzos isn't nice, but its nothing compared to living with no sleep aid for me.
That sounds horrible. You need a private doctor to inject you with Propafol every night like Michael Jackson had
Sodium oxybate is sometimes prescribed for narcolepsy and insomnia class sleep disorders, it's literally GHB, similar effects to this. GHB isn't too hard to get on its own even without a prescription I'm surprised you haven't just tried that. Or the various animal tranquilizers that are super effective. Xylazine was being put in fent mixes to induce hard sleep, but it causes necrosis when IV, wouldn't recommend except for oral use.
@@Pepesmall ghb is hard to get where I live. gbl is easy, and its metabolised to ghb n the body. After two days I had to take a dose so big, it made me vomit so hard I cried and sweated a puddle. I get very fast tolerance to all gaba related stuff, probably after 7 years of studies which I passed, but I wasn't able to finish the final diplom work because during apendectomy anaesthesiologyst ruptured my lung and trachea due to too high pressure and mythin tissue layers, and it got iftected, I got sepsis gad 20% chance to live, survived, but got depression and ptsd and then after a massive migration of ukrainians I've got scabies from one of them and I can't cure it since few months, I spend thousands of $ every month for substances that are almost sold for free in USA but not here, and every time there is some piece of clothing I forget to sterilise or some weird place they manage to hide in, and they come back. And all of my studies went into nothing, like it never happened. I sacrificed my liver, most of health physical and mental for nothing.
@@Pepesmallghb is highly addictive too tolerance builds extremely fast and duration is short. It’s prescribed for narcolepsy not just because it induces sleep but also due to it affects sleep patterns.
This guy may benefit from using ghb once in a while but not daily. Benzos are probably a better choice for treating insomnia.
lol i do too and i have a chemical cure not fkn heroin 😂😂😂
This is so cool, I've been waiting for this video
0:47 I take a strong disagreement with that statement. I've taken benzodiazepines once, and I would not describe it as removing anxiety, a more apt description is that it stops your ability to care about the anxiety, you still feel the anxiety, your brain just doesn't care about it.
I took Valium for a surgical revision that I wasn't sedated for. Usually that sort of thing would cause me to freak out so hard I'd pass out, but the Valium brought me to a normal anxiety level. Just took me down a notch I suppose
I've been on Valium for 20 years and it massively massively dulls the anxiety. I wouldn't say it doesn't make you care about it.
well.. you’re not everyone. I used to both take prescription benzos, and abuse them, and illegal benzos, because it essentially turned my anxiety off completely. I used to get bad anxiety after a while from smoking pot, and if I took a bar and smoked, there would be nothing. I had a great time every time. just as an example. The only thing that worked similarly well for me was Gabapentin. SSRI’s make you feel like a zombie. I guess it works in that aspect for its anxiolytic effects, but I didn’t like feeling like an emotionless zombie.
It completely crushes anxiety attacks in my case . It’s such a miracle drug in my opinion
Well iv taken a dozen different types in the 1000’s of times and you’re wrong
At first, I thought u meant flunitrazepam.
Thats wild making benzos.
As someone with anxiety, I'm gonna push back hard on the intro. While they solve the feeling of anxiety at first, they have the dual issue of (1) very quickly increasing tolerance and (2) tending to be counter-productive to CBT based techniques for long term change. In particular, they fuck with your memory HARD. Some people aren't too affected, but even therapeutic doses give me a sort of almost blackout "video tape" memory where I can only remember flashes.
Benzos absolutely have their use. They work excellently in an inpatient setting, and they even have some great uses for short term effects. But they really are not good for chronic anxiety disorders. They're about as effective as alcohol where mostly they make you stop caring.
u know u can cure anxiety right? guess u aint above 100iq loser
That one is close to my favorite one - flualprazolam
No analytical data at the end? 😢
gotta keep your plausible deniability as far as accidentally creating any illegal products. assuming he has properly disposed of everything he made in this video, nobody will ever be able to prove that he made something illegal if he somehow did by accident. Can't say the same if you use a university's NMR or mass spectrometer to analyze your products, those test results will be stored somewhere out of your control from which the police can subpoena them.
Designer benzodiazepines completely ruined my life.
I attempted to self delete, totalled 4 cars, got 3 duis in one year, lost my wife, my 3 sons, my house, my money and I actaully didn't lose them till after rehab and sobriety.
Clonazolam was what got me.
Oh and I was facing 15 years in prison thanks to the failed deletion attempt because it was by OD on fent/bromazolam.
Man that looks mighty tasty
**Jordan Peterson enters the chat**
With a huge bag of xannies and a bunch of "pick me up" meth
@@uberneanderthal as long as we're not synthesizing apple cider, he should be safe
juden peterstein?
Dude just couldn't hold his existential dread.
The full resources of our fanciest university behind him, and nobody would slap him together a damn taper?!
@@sakurakiyori he was always a meth & xanax junky, plus the whole tyranny fetish saga
I am not sure that i like this trend of everyone getting into psychoactive substances on YT nowadays, but the video itself was very cool to watch as usual.
If I hadn't read chemistry A and B, or trimesters 1 and 2 as some countrys call it, I would have no clue to how to follow what you are doing (Like you just say TLC instead of Thin Lair Chromatography), however this procedure makes me wounder how the hades they did discover benzos in the first place, I mean it's not all that obvious, and who did they test it on to find out the properties of it on humans?
I assume they found precursors had some effect and probably tested it on animals first. Then again it was the 50's so maybe they just YOLO'd it
@@creature2479 Yeah, but what compelled a random chemist to do this quite complicated procedure to get to this molecule in the first place?
There must have been a pre-thought behind it, you just can't just arrive at this at random.
Usually it starts out by discovering an effect by some plant or animal made chemical, as it gets tested out its structure is identified and then chemists usually fuck around and find out, one way or the other
@@williamabrahamsson2945 prolly some kind of plant material was found by tasting something for characterisation(old chem books have color, crystal shape, smell AND TASTE listed as properties at stuff like mercury and crazy shit like that) that had some kind of effect. then they fucked around with the molecule and found other analouges
@@williamabrahamsson2945 Journal of Medicinal Chemistry
Volume 22, Number 1 January 1979
The Benzodiazepine Story . Sci Hub to help a poor student
We gettin on the list with this one. Well, let's be honest we are are already there, just bumping us higher.
Benzos have stopped my heroin addiction just to get into a 10 times worse benzo addiction. Although they ruined everything i still cant hate them just because how good they make you feel
Spoken like a true addict. 👏
@@interstellarsurfer I stopped a year ago, but just thinking about how cruel the withdrawal was makes me shake
😂 u just don't know how to reset ur gaba a recreptor dummy
i got a chemical that resets gaba a and b
@@AlexanderSchwarz-ck3cx10 year long opiate addict.. the last year before I got clean 2022 I had unlimited farmapram's. Coming off of those and fent even with methadone was pretty rough.
10:38 I like how he also glosses over the reaction requiring hydrazine like it's no biggie
Make some nitazenes next
Mmm super fentanyl 😋
You should follow this up by making Flumazenil which is an antidote for benzo OD
Benzos are fantastic, just as long as you disregard any prescription that would have you take them as a daily medication. When I was prescribed alprazolam i adopted the principle of once a dose is taken it must be fully out of my system (~72-96 hours) before I will allow myself to use it again.
Works absolutely perfectly when I need it, at the same dosage i was originally prescribed (.25mg - 2mg depending on why im taking it). Never ran out, never had to ask for increases.
Most people do Not have Your discipline .
They should be banned outright and never prescribed for any reason. They are terrible.
Yup that's how it's done....
Finally that's something that will help me wen the world ends
You should bring a natural product back. Your geosmin project went awry in the reductive deoxygenation of the tosyl ester step. Maybe find a work around or even a different molecule altogether?
Oh hell nahhhhh (now make flualprazolam)
Oh HELLL NAWW, make CLOnazolam
Clam is too good. Flualp is too. Now days bromazolam is the most accessible.
Ugh, been dealing with these things for so long. Haha. Glad I dont use them anymore though.
Man i love your chemistry
I've tried that one lol
Yes it was widely available on the RC Market
Definitely the most potent one out there
shit made me black out for days at a time i'd just keep taking more while feeling like i'm sober until i woke up 3 days later
@@hehexd11231 I can relate to that really the most potent one out there
Clonaz was a good one too. Nowadays bromazolam is the most widely accessible, but yeah I'm glad I got away from using them. Withdraw is fucked.
lol i was hooked on this specific benzo. horrible times, its very strong and really potent
Got a good supplier?
@erickkenneth3391 those research chem sites, no certainty until u order
All the fiends online want eitizolam
my ex would comeback if i said i have that xD
I know it’s not gonna happen but every day I’m praying for a video about cathinones 🥺
MXE next pls
the holy grail of the RC community!
Man this Video is great! Im so interested in more of These drug Synthesis videos.
Never clicked a video so fast
Drug addict
Flunitrazolam is a evil one very ahort acting and sooo addictive
Yes Ma'am here is something that will barely work at all but costs an arm and a leg. That is why I left Pharmacy and went back to school for many years....UGH....I am now starting a gourmet and medicinal mushroom business in Delaware. Mainly Blue Oyster, Golden Oyster, Reishi, and shiitake mushrooms...There is reputable literature showing high rates of tumor regression from 95 to 100%. Especially Reishi....
Yeah sure
I get diazepam, been on them for a long time, 20 years long time, and I have schizophrenia so I don't find it hard to get them when I ask if I'm having a hard time, though, don't stay on them for too long, coming off them is crazy, you can literally feel the juices moving around in your head trying to figure out what to do when you come off them after taking too much for too long. Full scale mental breakdown.
Truly amazing work! I'm very impressed.
My kids love this recipe! Thank you for this
Watching videos like this makes me wish I had a better Chem professor in college. Mine was such a butthead (putting it nicely), I hated his class and didn't learn much.
I wish this channel stays alive