This was the one concept I absolutely could not understand no matter how many times I read the chapter, went to tutoring, watched other videos, etc.. until now. Thank you so much.
Thank u Leah ...surprisingly for every speck of doubt in organic; I'm instantly reminded of your videos and every time you come to my rescue since you explain things wonderfully!
My professors of the past never really handled teaching this well when it came to assigning configurations for more complex molecules (especially cyclic compounds). Your video, however, had me up to speed in a matter of minutes. Thank you! This was a super helpful explanation.
I'm 2 days before my exam and so lost with R and S configuration with organic chemistry THANK YOU SO MUCH you're legend, that's so easy to follow and to understand
Oh wow, so glad this came at the perfect time for you. Make sure to watch the entire series so that you catch all the different ways of solving these problems simply
My teacher barely went over this. Thankyou for this clear breakdown on what to do. I recommended to my teacher to teach the breakdown like this as his lecture didn't really explain why he was choosing the paths he chose beyond one molecule or ring.
Sulfur is attached to carbon attached to carbon attached to the chiral carbon. However, since we don't look all the way out on the chain. Instead only look at the atom directly attached and compare. C-O beats C-C-S due to being closer to the chiral carbon
Hi Leah.....your lecture videos are really amazing... you made them look so simple even though they are tough to understand. Can you please do a lecture video of converting Newmann to saw horse formula and vice versa....of both a single chiral as well as a two chiral centred carbon molecules??
Thank you SO MUCH! No one else including multiple youtube videos and even my professor ever adress what to do when the atom is surrounded by carbon chains! It's a real problem if your professor tells you to determine the rotation of all 50 stereocenters of Gargantulide-A for a take home project!
Hey Leah, you're videos are the best organic chemistry resource I've come across online. I went through the Chirality and Fischer Projection videos on your website and couldn't find anything in regards to Diastereomers and Meso compounds other than the cheat sheet. Have you made any videos on those topics? Also, finding chiral centers in complex skeletal structures? Thanks again!
The videos that I have made on those topics are housed in the Organic Chemistry Study Hall. These Study Hall videos are longer and more in depth than the free videos that I share on TH-cam or on my website. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
How do we decide which secondary atom to count next? In other words, when we’re doing a tie breaker and an initial carbon (bound to the chiral center) is bonded to another carbon and an oxygen - do we count the oxygen or the carbon first?
We actually take all of the atoms (that the initial carbon is bound to) into account. For example, one initial carbon may be bound to an oxygen and carbon while another is bound to TWO separate oxygen atoms. That one would outrank the other, according to Cahn-Ingold-Prelog priority rules, because two oxygens are higher in atomic number than one oxygen with a carbon. For more on ranking substituents according to priority, I suggest taking a look at my full series and cheat sheet at Leah4sci.com/chirality
If I needed help you would be the #1 choice Leah. But I'm just watching for fun. Many thanks for your great videos! I would love to support you by purchasing a kit but the link you give doesn't work.
Thank you so much for watching! I really appreciate the support. I don't see any issues with the link. First, go to Leah4sci.com/Kit and then click on the first linked text that reads "Molecular Visions Model Kit (Amazon)".
does it matter what direction you go with carbons on the phenyl ring because you couldve gone up and gotten the double carbon bond before you went down and decided earlier it was number 1 priority
Great question! The conjugated system of pi bonds in a benzene ring resonates in a complete circle. That means, no matter which way you go around that ring, you are going to have at least partial double bond character. The phenyl substituent will always outrank the cyclohexyl group.
I'm sorry, but I don't offer tutoring through TH-cam comments. For help with this and more, I recommend joining the organic chemistry study hall. Full details: leah4sci.com/join
The Phenyl has pi bonds on all Carbons since the bonds are in 2 spots at once, forming that donut shape (that's why it's drawn with a circle, not double bonds, see Crash Course Chemistry), so that wasn't the best example there. The answer was still the same, but not very clear.
I have a separate video for that in this series. leah4sci.com/chirality-stereochemistry-enantiomers-diastereomers-r-s-organic-chemistry-tutorial-series/
I hope you get everything your heart desires. You are saving lives out here
aww thanks. glad I can help :)
This was the one concept I absolutely could not understand no matter how many times I read the chapter, went to tutoring, watched other videos, etc.. until now. Thank you so much.
You're very welcome, so happy to help!
Finally someone who explains the priority of double bonds! God bless you.
Glad the video helped! You're welcome!
Thank u Leah ...surprisingly for every speck of doubt in organic; I'm instantly reminded of your videos and every time you come to my rescue since you explain things wonderfully!
You're so welcome, I'm happy to help!
You are the smartest, the most confident, and the best!!
Awww thanks!
your explanations are superb leah
Glad you like them!
My professors of the past never really handled teaching this well when it came to assigning configurations for more complex molecules (especially cyclic compounds). Your video, however, had me up to speed in a matter of minutes. Thank you! This was a super helpful explanation.
Glad it helped!
Leah, God bless you, no one explains chirality like you do. Forever grateful 🙏
Wow, thank you, and you are so welcome!
This is the only source I could find that actually helped to solve any complex problem for R and S
thank you !!!!!
You're very welcome!
I m also a teacher... was struggling with this system... bt u saved my mind ... lov u really... salute
Glad it helped!
I am seriously so thankful for you, I have such a better understanding of all of this. Life saver is an understatement.
You're very welcome!
I'm 2 days before my exam and so lost with R and S configuration with organic chemistry THANK YOU SO MUCH you're legend, that's so easy to follow and to understand
Oh wow, so glad this came at the perfect time for you. Make sure to watch the entire series so that you catch all the different ways of solving these problems simply
My teacher barely went over this. Thankyou for this clear breakdown on what to do. I recommended to my teacher to teach the breakdown like this as his lecture didn't really explain why he was choosing the paths he chose beyond one molecule or ring.
You're welcome, and I'm so happy I helped you to understand! Sometimes it just takes seeing it a different way for it to click.
I used to hate complex structures but you've made it fun for me. Thanks for the help.
YES! My secret mission to make orgo fun is complete!!! ;) So happy to help!
Wow. I am amazed at how great you are at teaching this kind of stuff
Thanks so much for your kind words, I'm happy to share!
Hello ..i just want to thank you .. my exam is today and you saved me.. i appreciate your hard work keep on
You're very welcome! How did your exam turn out?
Leah4sci iam studying mechanical eng.. i think it was hard but i haveto succeed thank you ..from lebanon 🇱🇧
Madam ur a real teacher enough ever! thank you so Much
You're welcome
best video for understanding R and S conformation
Thanks! :)
Thank you. Organic chem is difficult. But you have made it digestible and easy to understand.
Glad it was helpful!
This class doest seem so bad with Leah as a tutor, thank you for all the help :).
You're very welcome!
Please I love you with all my heart
you just got a new subscriber... WOW
Thank you very verrrrrrrrry much
Thanks for subbing!
In the example at 3:56 I would like to know why you didn't mention anything regarding the sulfur on priority number 3
Sulfur is attached to carbon attached to carbon attached to the chiral carbon. However, since we don't look all the way out on the chain. Instead only look at the atom directly attached and compare. C-O beats C-C-S due to being closer to the chiral carbon
Hi Leah.....your lecture videos are really amazing... you made them look so simple even though they are tough to understand.
Can you please do a lecture video of converting Newmann to saw horse formula and vice versa....of both a single chiral as well as a two chiral centred carbon molecules??
Thank you so much! I'm glad you found it helpful and yes I already have videos on these topics
6 years later and she still explains it better than profs
Happy to help!
Thank you SO MUCH! No one else including multiple youtube videos and even my professor ever adress what to do when the atom is surrounded by carbon chains! It's a real problem if your professor tells you to determine the rotation of all 50 stereocenters of Gargantulide-A for a take home project!
You're so very welcome, happy to help!
THANK YOU SO MUCH
You're so welcome, happy to help!
Hey Leah, you're videos are the best organic chemistry resource I've come across online. I went through the Chirality and Fischer Projection videos on your website and couldn't find anything in regards to Diastereomers and Meso compounds other than the cheat sheet. Have you made any videos on those topics? Also, finding chiral centers in complex skeletal structures? Thanks again!
The videos that I have made on those topics are housed in the Organic Chemistry Study Hall. These Study Hall videos are longer and more in depth than the free videos that I share on TH-cam or on my website. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/
THANK YOU SOO MUCH this really helped me I just did not understand how we break the tie along the chain
You're welcome! Do you understand now?
you're an awesome teacher. Thanks a lot Leah!!!
Thank you! 😃
thank you for clearing my doubt
You're welcome!
Great channel on organic chemistry! 👍
Thank you so very much!
thank you so much...all respect to you from Algeria
You're very welcome!
Blessings to you. You are amazing, Leah🥹
Aww thanks so much!
seriously you are superb
Aww thanks!
Thank you so much, again I suceeded in doing something thanks to you !
Glad I could help!
How do we decide which secondary atom to count next? In other words, when we’re doing a tie breaker and an initial carbon (bound to the chiral center) is bonded to another carbon and an oxygen - do we count the oxygen or the carbon first?
We actually take all of the atoms (that the initial carbon is bound to) into account. For example, one initial carbon may be bound to an oxygen and carbon while another is bound to TWO separate oxygen atoms. That one would outrank the other, according to Cahn-Ingold-Prelog priority rules, because two oxygens are higher in atomic number than one oxygen with a carbon.
For more on ranking substituents according to priority, I suggest taking a look at my full series and cheat sheet at Leah4sci.com/chirality
you're very good teacher, thanks
You are welcome!
If I needed help you would be the #1 choice Leah. But I'm just watching for fun. Many thanks for your great videos! I would love to support you by purchasing a kit but the link you give doesn't work.
Thank you so much for watching! I really appreciate the support. I don't see any issues with the link. First, go to Leah4sci.com/Kit and then click on the first linked text that reads "Molecular Visions Model Kit (Amazon)".
This was what I was finding thank you leah
You're welcome Mohamed! :)
You’re a lifesaver ❤️
Happy to help!
Owe you a good chunk of my chemistry degree!! Thank you
Wow, glad to help!
does it matter what direction you go with carbons on the phenyl ring because you couldve gone up and gotten the double carbon bond before you went down and decided earlier it was number 1 priority
Great question! The conjugated system of pi bonds in a benzene ring resonates in a complete circle. That means, no matter which way you go around that ring, you are going to have at least partial double bond character. The phenyl substituent will always outrank the cyclohexyl group.
Excellent presentation.
Thanks so much!
maam, can we use the same method for R and S determination for isoleucine?
Absolutely!
You saved lives.
Glad I could help!
Very good
Glad you liked it
thank you ....very easy and smart ....very nice channel
You're very welcome, glad you like it!
You the REAL MVP
thank you!!
thank you so much leah..
i wish my professor could teach like you..
love you :D :P
You're so very welcome!
How do you figure out whether C atoms in a cyclic compound are chiral or achiral?
same as for acyclic, look to see if there are 4 unique substituents. if the first atom is the same keep going till you find a point of differentiation
So in a C-C triple bond, is it as if the carbon is bonded to 3 carbons?
Exactly!
How to perform the method of swaps which contain more than one chiral centre? Please do reply fast.
I'm sorry, but I don't offer tutoring through TH-cam comments. For help with this and more, I recommend joining the organic chemistry study hall. Full details: leah4sci.com/join
You save my life!!!
I'm glad I could hlep!
thank you soooooooooooo much
You're welcome :)
Thank you so much you’re the greatest
You're welcome! :)
The Phenyl has pi bonds on all Carbons since the bonds are in 2 spots at once, forming that donut shape (that's why it's drawn with a circle, not double bonds, see Crash Course Chemistry), so that wasn't the best example there. The answer was still the same, but not very clear.
Thank you for the feedback
thanks so much you have really helped me. bless u
you're welcome, happy I could help!
You helped me so much thank you!!!!!!!
Great! Thanks for visiting. Don't forget to subscribe! :)
what if the hydrogen group is not always in the back ? and it's a wedge
I have a separate video for that in this series.
leah4sci.com/chirality-stereochemistry-enantiomers-diastereomers-r-s-organic-chemistry-tutorial-series/
THANK YOU SO MUCH !!
You're so very welcome!
You're the best .. thank you
You are welcome!
God bless you 🙏
Thank you!
Thank you
You're welcome
I can understand easily
Great!
thank u for this video it is amazing
You're welcome!
Thank you 🙏🏼🙏🏼so much 🙏🏼
You are so welcome
Fantastic
Thank you so much 😀
You’re very good
Thank you!
Thank You!
You're welcome!
Thank you soooo much!
I've been understood enough, hehe
You are so very welcome!
Thank you very much
+Leah Fisch make a video to explain us how to build the fisher projection please
You're very welcome!
thank you
You're welcome!
gracias señora
You're welcome!
I LOVE YOU!
Thanks!
YOU ROCK!
Thanks!
Hi madam
Hello
How are you
Your classes nice madam
thank you so much
You're welcome!