CRISPR from a Bacteriophage Perspective

The most common analogy for CRISPR systems is that of molecular scissors. Joe Bondy-Denomy offers an alternative analogy from the bacteriophage perspective, all based on scientific data.
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[@natashalion8028]

Genius ! Mind Blown.

[@unays]

Thank you

[@sandramariasajan8206]

BRILLIANT

[@Viabel100]

Thanks

[@manuklinkz2691]

Amazing presentation, one question that i need clarification: what can we do with this ? i 'm a bit confuse here, Crispr cas9 does the cut and then a extra DNA is added and the cell "repairs the DNA that is cut " with the new ADDED DNA". Phages on the other hand usually "infect" the cell (in this example) to replicate (a little bit like a virus if you want, but not a virus but the process i mean). Now if CAS9 find the phage DNA it can destroy phage DNA (becoming prime !? not sure if i got it right !?) hence making cell immune to that kind of phage ? i guess. I hope i'm on the right track. But the second phage of any other except the first one (r.i.p. first phage died in combat like a warrior, sorry ...)can create a protein that will block CAS9, now making the cell vulnerable to that phage and blocking CAS9 from making the cell ever prime to that phage. Seem like a internal war in the cell CAS9 vs Phage , but my question is what can we do with this ? Like we can put the new DNA with Crispr CAS9 and it will edit (if we don't have phage on that cell or E.coli) or maybe we can put the DNA inside a phage (not sure about that part still learning about them...sorry for the confusion, but i think i was done before...please correct me if i'm wrong..thank you). But i fail to see why one would use both CAS9 and Phages to add DNA to a the cell? ahh..... man of man, it was suppose to be a simple questions...sorry i'm just curious as i find this fascinating. Good job Sir, i'm sorry if i made you guys and girls lose your time, I'm just to stupid to understand it. Thank you in advance to the ones that want to explain this to an idiot like me.

[@konatachan7059]

Ikr! Scientist who study bacteriophage and crispr-cas9 has different views. On the bright side, phages also helps kill bacterias in our body but they should have nothing to do with each other.