Synthesis of alcohols using Grignard reagents I | Organic chemistry | Khan Academy

แชร์
ฝัง
  • เผยแพร่เมื่อ 11 ก.ย. 2024

ความคิดเห็น • 52

  • @ProfessorDaveExplains
    @ProfessorDaveExplains 8 ปีที่แล้ว +39

    Pentavalent carbon? That's a sin! I think there are quite a few errors in this mechanism, most evidence points to a grignard reagent being polar covalent rather than ionic, not to mention the carbon with four bonds plus an electron, that ought to be a physical impossibility, carbon being one of the only elements that strictly follows the octet rule.

    • @nickt2575
      @nickt2575 8 ปีที่แล้ว +17

      +Professor Dave Explains beef

    • @steveharold8796
      @steveharold8796 8 ปีที่แล้ว +1

      few odd mistake fair enough dt we all make some from what ur video havent quite made the cut..appreciate rather than bringing someones effort down

    • @ProfessorDaveExplains
      @ProfessorDaveExplains 8 ปีที่แล้ว +26

      +Steve Harold i'm not trying to bring anyone down, those of us that put out educational videos have a responsibility to make sure they are of the utmost accuracy. if there are errors, they should be pointed out so that misinformation isn't propagated.

    • @steveharold8796
      @steveharold8796 8 ปีที่แล้ว +4

      +Professor Dave Explains sorry for being defensive

    • @coreyisgur737
      @coreyisgur737 7 ปีที่แล้ว +1

      I'm sure that you know a whole lot more about organic chemistry than I do but I'm not really seeing your point. My understanding is that a covalent bond, though I'm a little nervous to present a maxim, is only formed between two nonmetal atoms. So, wouldn't that mean that the carbanion's interaction with the Mg would be ionic? Further more, wouldn't that make sense due to the fact that we are talking about ionic interactions? Again, not saying that you are wrong, but the way that this video explains the interactions between magnesium and carbon seems solid. Also, where are you seeing a pentavalent carbon? The only place that I was able to find one was during, what I assume to be, a concerted mechanism in which the Mg donates a single electron to the carbon and the carbon-halogen bond is removed. I am truly curious so please let me know, thanks.

  • @Baidyabati
    @Baidyabati 11 ปีที่แล้ว +2

    You are probably the best tutor ( in organic mechanisms) I have ever come across in You Tube. Please keep up the good work.

  • @lucastavares5872
    @lucastavares5872 2 ปีที่แล้ว +2

    This is great. Just a note that H3O+ might be too strong of an acid in these cases, our professor recommends H4NCl.

  • @afnan-gi2nj
    @afnan-gi2nj 5 ปีที่แล้ว +1

    أنت عظيم بجد! 👏💜

  • @rounaksahu3716
    @rounaksahu3716 9 ปีที่แล้ว +3

    very very impressive.. Thank u Guys u r making studies so much comfortable

  • @Virtu3Ly
    @Virtu3Ly 11 ปีที่แล้ว

    You're my hero!!!!!! You explain this a million times better than my professor. Thank you!!!!

  • @jackyd4375
    @jackyd4375 11 ปีที่แล้ว +2

    or you can pause the video do the rxn and watch if you did the steps right. :)

  • @musiqal333
    @musiqal333 11 ปีที่แล้ว +1

    Very good explanation. I like. Although yes, I feel you do speak quickly, I followed along!~

  • @imbored193
    @imbored193 11 ปีที่แล้ว +1

    Awesome explanation! Thanks so much! Had to replay it a few times, spoke a little too fast for me lol

  • @decsjr
    @decsjr 10 ปีที่แล้ว +1

    This was great, thanks!

  • @simahakimi4942
    @simahakimi4942 10 ปีที่แล้ว +1

    Perfect! Thank you!!

  • @XvidGamingPC-HD
    @XvidGamingPC-HD 9 ปีที่แล้ว +2

    Thank you, that's really helpful, I really appreciate it.

  • @mseve4271
    @mseve4271 10 ปีที่แล้ว +1

    You're a Lifesaver!!!!!!!!!! Thank you!

  • @Baidyabati
    @Baidyabati 11 ปีที่แล้ว

    Wow that is just superb !!!

  • @ranamohamed9497
    @ranamohamed9497 ปีที่แล้ว

    Thanks 😊

  • @NATI3218
    @NATI3218 8 ปีที่แล้ว

    On the example with the formaldehyde, you attacked the carbonyl using the ncarba nion but should there be an arrow showing the MgBr leaving?

  • @isachinq
    @isachinq 10 ปีที่แล้ว

    Thanks! Very useful...

  • @darraghh6384
    @darraghh6384 7 ปีที่แล้ว

    this was a quick and dirty explanation of the mechanism. nice.

  • @rickykay2024
    @rickykay2024 9 ปีที่แล้ว

    Thx so much !!!!!!!!!!! U r the best!

  • @ccrunnerx92x
    @ccrunnerx92x 11 ปีที่แล้ว

    Is the Grignard reaction a nucleophilic substitution or addition?

  • @kinpatchifox
    @kinpatchifox 9 ปีที่แล้ว

    The type of connection between CM and the type of connection between Mg-X ??

  • @rubin831
    @rubin831 9 ปีที่แล้ว

    Genius!!!!

  • @danthedan2
    @danthedan2 10 ปีที่แล้ว +5

    Why is it for the second example that the methyl group went away?

    • @eliacalderon9571
      @eliacalderon9571 10 ปีที่แล้ว

      I just paused the video and am thinking the same thing...because once the methyl group is added it will no longer be a secondary, but a tertiary alcohol...

    • @saviour175
      @saviour175 10 ปีที่แล้ว

      The methyl group was still there and it is a secondary alcohol since the alcohol group was attached to a carbon which is bonded to two other C atom.

    • @benbrak3713
      @benbrak3713 7 ปีที่แล้ว

      same question in my mind right now

  • @ladybug22bulldogs
    @ladybug22bulldogs 11 ปีที่แล้ว

    Nice bro!!!

  • @Raisuru
    @Raisuru 10 ปีที่แล้ว

    quick question, what are the differences between the half-headed curly arrows and the normal curly arrows?

    • @SubliminalSixtyFive
      @SubliminalSixtyFive 10 ปีที่แล้ว +5

      The half-headed arrow illustrates one electron being moved and the full headed arrow shows two electrons being moved

    • @Raisuru
      @Raisuru 10 ปีที่แล้ว

      SubliminalSixtyFive Thank you

  • @pamelageorge3487
    @pamelageorge3487 6 ปีที่แล้ว

    wait why does only one electron from the Mg attack the methyl halide? why not the pair of electrons

  • @p-vashmalik1115
    @p-vashmalik1115 7 ปีที่แล้ว

    sir kindly plz clear the 18 rule for organomettlic compounds ...

  • @Pepci26
    @Pepci26 9 ปีที่แล้ว

    Hey what about chirality for the aldehyde to secondary alcohol example? I am struggling with chirality and would appreciate some guidance. Does anyone know of a good video explaining chirality in grignard reations?

  • @Winniethepoohx000
    @Winniethepoohx000 6 ปีที่แล้ว +1

    Thank you SO much! I have the worst professor ever ):

  • @passntesam3346
    @passntesam3346 ปีที่แล้ว

    ❤❤❤❤❤

  • @salmankazi5308
    @salmankazi5308 9 ปีที่แล้ว +1

    Could any one tell whats is " E+20 " above the arrow...??

    • @annehiggins519
      @annehiggins519 9 ปีที่แล้ว +1

      +Kazi Salman It's Et(2)O, which is diethyl ether

    • @salmankazi5308
      @salmankazi5308 9 ปีที่แล้ว

      Annie Higgins​ Thanxz A Lot..

  • @iftixarhuseynov3199
    @iftixarhuseynov3199 9 ปีที่แล้ว

    Thanks , very beneficial ...