Grignard Reagent Reaction Mechanism

This organic chemistry video tutorial discusses how to use the grignard reagent to reduce ketones and aldehydes into secondary and tertiary alcohols. It also explains how to reduce esters and acid chlorides to alcohols using the grignard reagent.
Organic Chemistry - Video Lessons:
www.video-tuto...

[@TheOrganicChemistryTutor]

Organic Chemistry - Video Lessons: www.video-tutor.net/organic-chemistry.html

[@endex-s6y]

tnx

[@vedavalliv9597]

The word "thank you" is not enough for your efforts! It helps us a lot! Love from Tamilnadu,India❣

[@thangam5006]

Sis I'm also from Tamilnadu

[@vedavalliv9597]

@@thangam5006 🙌

[@ganeshsriram4941]

You are right, This video is helpful... And I'm also from Tamilnadu...

[@vedavalliv9597]

@@ganeshsriram4941 :)

[@AnkitJosh]

I'm not from Tamil Nadu but I'm from India

[@donaldmusenje5120]

This guy he is a genius he has helped me to understand in all my natural sciences and mathematics. I don't have enough words for him but all I can say is that may God continue blessing with whatever you need in your life. You have helped me personally through out my university life for 4years. Last but not the least please don't stop with what you do continue to help the future generation 💪🙏🙏❤

[@donaldmusenje5120]

From zambia

[@Shred427]

This vidéos are so well explained, and help a lot to understand more easily the dark side of organic chemestry, so i need to say : Big thanks!

[@Krisbrianasadie]

Thank you for all your videos, I passed both organic chemistry courses with good grades because of you

[@theobanai]

Teacher nehi padhate the kya😕

[@sounad3736]

@@theobanai tujhe teacher nehi padhate? Tu yaha kya kar raha hae ghochu?

[@KawaiiBabyTragon]

I needed this so bad last semester, thanks for making it now anyway.

[@meya4307]

So basically, since feb. 2020, you've been my instructor. And THANK YOU SO MUCH.

[@237BrillantBABOKA]

Cette vidéo m'a rendu moins bête 😀, merci beaucoup Monsieur.L'anglais est vraiment très important pour la poursuite des études supérieures, dommage pour moi car je ne comprends pas...( BABOKA, DEPUIS LE CAMEROUN)

[@chemchristv]

You are the best.... I want to be like you... Since my year 1 I have been using year video... Now I am a chemistry Tutor I am still watching your videos.. for proper explanation..
Thanks alot

[@cedricchurch3632]

This video jusy came in really clutch for my 1st orgo 2 exam. Really preciate ypur vidoes they helped me through physics too

[@Megan-je2lr]

you deserve an award of some kind. you are the reason I'm passing my final in 2 hours :)

[@mr.madguy6125]

😂

[@depharmily2064]

you are the reason i do well in my exams and tests

[@neilmashalkar5203]

great video! just some advice- keep the picture of the final product up for a few seconds longer- i can’t pause the video fast enough to see the product alone

[@guiaf_]

Hope you're making millions by now my dude

[@walterblack91]

hope he does....he deserves it totally

[@cheinapore7951]

I'm dying to understand this topic but there you are, you always save me😭 thank you so much! Have a nice year!

[@dianed4938]

you made me fall in love with chemistry through your videos

[@cringespot2928]

Thanks from Tamilnadu India 😍😀

[@aarongurung786]

My man's carrying my entire organic department staff

[@valent9260]

mann..... i wish could hire u privetely as my chemistry olympic mentor

[@JiyonKim5]

first time i feel like im understanding ochem!!! thank u so much! :)

[@surafeltesfu9953]

you are the most intelligent teacher i ever know !! thanks

[@a0927020973]

4:28 Why magnesium will insert the carbon atom?

[@gemlovergirl]

You are the best tutor!!!

[@rohanbhide4495]

thankyou for this video! You have selected the best questions and the right amount of questions for this topic! I really appreciate it!

[@raphaelkirangole4031]

Thank you for your video 🙏🏽 it is really helping me following from Kenya

[@negar21100]

@7:03 Why didn't O get protonated at this moment? Why did it kick the OCH3 out instead?

[@Wagonburner3five]

Thank you for making me understand the addition of 2 R-groups.

[@nanditasanghvi]

thaank you so so much
you are brilliant and your teaching style is amazing

[@MoeZokari]

Thank you sir... you are a life saver... wallah

[@hasanaliameal4298]

Thank you very much I am from Iraq and you help me by this lessons

[@samajhdar3853]

Thankyou , your deep explanation is attached to show more than one video and you are show everything in rxn ,what I to do.
India (Hindi)

[@Naomicool100]

A big „thank you“ from Germany 😇👌🏽

[@ashokkumarsharma5666]

Surely a nice video with good explanation and high order jee leve questions

[@EyehatePersona5]

wdym

[@tomatrix7525]

Thanks man these are really great to watch

[@Household-rn1pc]

Thank you so much for solving my problem ❤

[@joshuaschamach4684]

Highest grade on my O Chem 1 final. High A in the class. Gracias.

[@amirfilabs7716]

At 12:18 I believe this is an epoxide ring opening under basic conditions so the OH lands on the more substituted atom, please correct me if I’m wrong

[@harshbalhara4389]

Thanks sir !!!!
Great love from INDIA.
You really help me often!!

[@shashaniou4]

thanks for your teaching!!

[@duaamohamed5480]

Am so proud of you

[@An_ony_mous]

Thanks alot. Now wherever I see RMgX I won't make mistakes.

[@uditvarshney3653]

4:14 how can you make it Grignard reagent without dry ether

[@DevilMode-pd8el]

Thank you so much sir 💖from TN(India)

[@GoogleAccount-mz6vn]

At 7:14 why didn't the O¯ get protonated and turned into an alcohol instead?

[@Frame381]

You are a saving grace! Thank you so much

[@manishjat6263]

nice bhai

[@zincion1]

Great video!

[@ujjwalkumarsingh5216]

Thanku sir ..I had confusion in this part

[@Ak-ix2xp]

You're such a gem

[@ritankarmondal0411]

Can't thank you enough man! I was facing doubts in grignard reagent and this cleared everything!
And a quick question. For the compound in 9:45 won't a ring expansion be more favourable before the addition of the -R group?

[@ashaydwivedi420]

this is an SNAE mechanism! rearrangement is only possible when a carbocation is formed. this reaction involves carbanion nucleophile and no carbocations are formed, so no rearrangements

[@laurensadowski-o5n]

9:28 are there supposed to be that many carbons attached to the grignard reagent?

[@shihab5689]

Love from Bangladesh 😘.

[@jesusmrosario-claudio4104]

Thank you once again.

[@fantasiaford1283]

So, the Ch3Ch2, we use it twice because we need the oxygen to be negative in order for it to do the proton transfer of hydronium? So it can be an alcohol?

[@fredt8167]

At 3:35, if we had to name this structure would be it be (A) 1-ethyl cyclohexanol or (B) 1-ethyl cyclopentanol? If its (B), why? when counting the longest chain starting with the ethyl group

[@cunningclown7422]

Thanks! Cleared my concept very well!
Great explanation!

[@BlackMamba0175]

Appreciate you Mr.💯

[@rohanbansal2324]

excellent video my man. keep up the great work

[@billalzerouali4472]

Why is at times the h30+ is written under the arrow and other times it isnt even though its still used

[@ericraululyeetusdelyeetus5028]

Had to go to this video after seeing a legendary meme about the reagent.
Who would've guessed a well edited clip of black'n'white daffy duck would be so funny?

[@aakashpatel9650]

Great session

[@kushagra5633]

Best explanation ❤

[@toxicevolution5940]

Doesnt it matter that you change the position of the CH3 Group in the first example?

[@brianshang1069]

Awesome vid, can't say it enough.I smacked that sub button

[@blessingschinkuyu]

thanks for all your videos

[@patrycjapajdak2491]

A very useful video, thanks!

[@haryanwar1263]

This better than my teacher

[@CR1257]

How do you know what side to put your reagent on? I keep thinking that you could choose either or because you’ll still end up with the same answer..? 08:26 I’ve seen others put their reagents on the aldehyde side and they’ve gotten it the answer right.

[@samarthgoswami5289]

Thank you kind sir!

[@darkphoenix6742]

Very efficient!

[@shammah5976]

example 4 at 7:34 why are there 2 ch2ch3 to react with??

[@urvitiwari6754]

is attack by GR always SN2? is there a possibility of rearrangement or ring expansion?

[@ivertylungu7834]

We really appreciate for your help

[@madeleineguzman5025]

where did we get the 2 carbons to add to the 4 carbon chain on the last problem?

[@svenvandeweerd7467]

great explanation!!!!

[@latte3728]

Thank you for your help!

[@bailassandijani3788]

could you please make a discussion about Reaction of Grignard Reagents with Epoxides
thank you

[@trentkirkwood4488]

Im learning from these this one just seemed like you were going kind of fast.

[@phenomenalphysics3548]

6:53 how do I know something is a good leaving group?

[@zhangzhengyifan6117]

the less basicity one group is ,the better it acts as a leaving group

[@ritikshukla1788]

The more stable the leaving group is as an individual the better the leaving group

[@ritikshukla1788]

(in the case of CH3O- the negative charge is on oxygen which is highly electronegative and hence the molecule is stable)

[@jeewanpreetkaur5872]

Which is individually stable that is gud leaving group

[@juststudy9989]

Hey dude u are OP

[@ramisamaliath8658]

Omg Thank you!!! This helped a lot

[@drakemastronardi4924]

At 4:49 was in the carbon partial -?

[@juststudy9989]

No

[@banny2263]

Love from india

[@devjyotisenapati8466]

Anyone prep for iit jee 2024

[@arkadeepjana7605]

Neet 2024 here

[@DevaChoco]

Csir here ❤🎉

[@shreyanshrastogi4416]

how did it go ?

[@lakshmananiyeraruna738]

Iit 2025 name L.Aditya

[@adityaReddy4162]

​@@lakshmananiyeraruna738PW sa Aya hai ra sir ka lecture ka baad

[@Lolstarwar]

Helped me a lot thanks

[@siobhanquinn4635]

I’m struggling to understand how you could only have three carbons and end up with four in the end ?

[@coder134]

That's really some morrison boyd lvl shit mann!! ❤❤❤

[@gillscape]

Very good

[@AdemAbdulmajid]

Very good your video

[@MekuantAbe]

Thanks from 🇪🇹🇪🇹🇪🇹

[@ignaciogarcia1888]

Buonara really got me

[@ThomasJere-co3dy]

Why upon reacting ethyl chloride you have included mgbr ethyl instead of using mgcl, but the grignard reagent cl

[@alderamin1402]

THANK YOU SIR

[@single-cellshark6013]

Badass. This guy is badass

[@pantelisafroudakis7117]

One question...if we add to the ester one mole of grignard reagent...will the reaction stop to the ketone? For example...if we have the solution of the ester and we add slowly and dropwise one mole of the grignard reagent in ether/THF solution ...will it stop to the ketone?

[@anonymus2280]

Yes if you are using only one equivalent

[@moazahmed6282]

Any one know the program he using in explication ?

[@swaroopdiddi3550]

Just realised this guy's comments section is filled not just with a single country ppl

[@ruq3tuieiotiyiiabyiuoyoppa413]

thank you sir☺

[@yashkalia2311]

Thanks

[@emmaaustin544]

Awesome! Thank you

[@LA-cm9uo]

You are an angel