Heres the 'Good News' About Prostate Cancer.
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- เผยแพร่เมื่อ 21 ก.ย. 2024
- Published in the New England Journal of Medicine, this study compares the effectiveness, side effects and long-term outcomes of active surveillance, the prostatectomy surgery, and radiotherapy in men diagnosed with localized prostate cancer over a fifteen year period.
Between 1999 and 2009, eighty two thousand four hundred and twenty nine men aged fifty to sixty nine in the UK underwent PSA tests. From these tests, two thousand six hundred and sixty four men were diagnosed with localized prostate cancer, and one thousand six hundred and forty three participated in the study, divided into three groups for different treatments.
The Three Different Options in the Study:
1. Active Surveillance involves regular Prostate-Specific Antigen (PSA) tests and clinical check-ups to monitor cancer progression.
2. The Prostatectomy Surgery involves removing the prostate gland to try to eliminate cancer.
3. Radiotherapy uses radiation to kill cancer cells.
The participants were followed for fifteen years. Researchers measured death rates from prostate cancer and any cause, development of metastases, disease progression, and the need for long-term androgen-deprivation therapy.
Here Are The Results
- Survival Rates: After fifteen years, the survival rates from prostate cancer were very similar across all three treatment groups. Approximately ninety seven per cent of men diagnosed with localized prostate cancer survived fifteen years, regardless of treatment.
- Disease Progression: Men in the active monitoring group had a higher rate of disease progression and metastases compared to those who underwent surgery or radiotherapy.
- Side Effects: Surgery and radiotherapy were associated with more long-term side effects, particularly affecting urinary, bowel, and sexual function. These side effects persisted longer than expected.
Here's The 'Good News' About Prostate Cancer:
The study found that the most common cause of death among the participants over fifteen years was not prostate cancer:
- 51.6% of deaths were due to other cancers and not prostate cancer.
- 31.8% of deaths were from cardiovascular or respiratory diseases.
- Deaths from prostate cancer itself were low, occurring in only 2.7% of the participants.
Here's The Important Conclusion for Men With Localised Prostate Cancer.
The study shows that while active surveillance avoids the immediate side effects of surgery and radiotherapy, it carries a higher risk of disease progression.
Men with localized prostate cancer have similar long-term survival rates whether they choose active surveillance, surgery, or radiotherapy and as you can see from the data presented here, the majority of men died of other causes and not from prostate cancer.
Each treatment option has different implications for disease progression and quality of life, emphasizing the need for personalized treatment decisions.
To help you do your own research, please find the expert resource links in the description below this video and please don't forget to let us know your thoughts on this topic in the comments.
If you're a man over forty years old who wants to protect your sexual health: avoid the leaking, bleeding, and erectile dysfunction caused by unethical surgeons performing more than seventy thousand unnecessary prostate surgeries each year, then join our private community at: prostatecancerw...
1. Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer. www.nejm.org/d...
2. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences: www.ndorms.ox....
3. UroToday: www.urotoday.c...)
4. University of Oxford: Study shows delaying treatment for localised prostate cancer does not increase mortality risk. www.ox.ac.uk/n...
5. BMJ: Fifteen year quality of life outcomes in men with localised prostate cancer: population based Australian prospective study. www.bmj.com/co...
6. National Institutes of Health (NIH): Comparing side effects after prostate cancer treatment. www.nih.gov/ne...
7. AAFP: Prostate Cancer: Newest Study Shows No Change in 15-Year Mortality Regardless of Treatment Strategy. www.aafp.org/n...
If any of you guys have questions you think we should be creating videos for in relation to prostate cancer, PLEASE let me know in the comments.
PSA test is not an indicator of prostate cancer. BPH and prostatitis are also causes of higher PSA.
A video on unconventional therapies, such as Dr. Seyfrieds metabolic therapies (going into ketosis, pulse restricting glutamine, hyperbaric treatments, and sometimes very low, targeted dosages of radiation and drugs) would be worthwhile. His therapies have been successful for all types of cancers.
@@brianrichards7006 Thank you for your feedback. There are many topics we want to cover but have to be careful with the extremely restrictive terms and conditions of all platforms about 'medical misinformation.'
Perhaps a video on new Focal Therapies such as TULSA and IRE and best radiotherapy with least effects. MRI guided HDR Brachytherapy would be great too. Excellent presentation…
Big business....for hospitals and surgeons....great video...thanks
what i would like to know is ,out of the men that died from other cancers how many had treatment ?