I'm planning on starting my own Bioinformatics project from scratch...so I'll be binging all of your videos soon :D Thank you so much for the free and high quality educational videos prof!
Recent examples of drug repositioning is Viagra. Viagra first use for angina and now recent studies show it also able to reduce the onset of Alzheimer’s disease.
Thanks for the kind words! To keep up to date on the latest developments in the field, I usually read papers, attend conferences, listen to presentations as well as experimentations. Oh and make lots of errors and mistakes, found that to be the best way to learn as well :)
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This is an awesome video with much-needed info in CADD in a comprehensive manner.. Thanks! I would like to know if a video of practical implementation in Python for drug repositioning is available
Hello professor, I have a question: if we have one specific ligand and want to find potential targets to bind the ligand, is QSAR the approach that should be applied?
hey prof, i got a question, when you say a compound is active or inactive do you mean it is a synergic or blocker compound? or it is simply a compound that interacts with the ligand or not?
Hi, As discussed in the video, ml model could be used to extract important features or substructures that contribute to activity of molecule. Will you please explain it how? Thank you
Random forest has a built-in feature importance known as Gini index which can be used to deduce the relative contribution of features (the X) on the bioactivity value (the Y)
@@DataProfessor Thank you, Professor I tried and it really worked. The next step is how to trace back to the substructure from 'important features'. A video lecture on this topic will be highly appreciated. Regards
Hi if you click on the Join link on the main page of this TH-cam channel to be a channel member then it automatically unlocks the rest of the videos in the library.
I'm planning on starting my own Bioinformatics project from scratch...so I'll be binging all of your videos soon :D
Thank you so much for the free and high quality educational videos prof!
That's awesome, and glad to hear that the videos are helpful :)
Recent examples of drug repositioning is Viagra. Viagra first use for angina and now recent studies show it also able to reduce the onset of Alzheimer’s disease.
Love the common questions slide, great layout. Your breadth of knowledge in informatics is off the charts, how do you keep up with it all!
Thanks for the kind words! To keep up to date on the latest developments in the field, I usually read papers, attend conferences, listen to presentations as well as experimentations. Oh and make lots of errors and mistakes, found that to be the best way to learn as well :)
Thank you so much Professor. It was Insightful and will help people like me who wants to switch career in Bioinformatics.
🌟 Join as a Channel Member to support us (and unlock this full course):
th-cam.com/channels/V8e2g4IWQqK71bbzGDEI4Q.htmljoin
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Sir please make one video to calculate descriptors and feature selection.
This is an awesome video with much-needed info in CADD in a comprehensive manner.. Thanks! I would like to know if a video of practical implementation in Python for drug repositioning is available
Hello professor, I have a question: if we have one specific ligand and want to find potential targets to bind the ligand, is QSAR the approach that should be applied?
It was very helpful, thank you so much.
Glad it was helpful :)
How to enroll for the full course Prof? 🙏 Thank you for your videos, always inspires...
That's a great question, the full course will be available for view by Channel members very soon.
hey prof, i got a question, when you say a compound is active or inactive do you mean it is a synergic or blocker compound? or it is simply a compound that interacts with the ligand or not?
Thanks Sir. If possible, please make a video on how to calculate descriptors
Excellent
Hi,
As discussed in the video, ml model could be used to extract important features or substructures that contribute to activity of molecule. Will you please explain it how? Thank you
Random forest has a built-in feature importance known as Gini index which can be used to deduce the relative contribution of features (the X) on the bioactivity value (the Y)
@@DataProfessor
Thank you, Professor
I tried and it really worked. The next step is how to trace back to the substructure from 'important features'. A video lecture on this topic will be highly appreciated. Regards
How can I get access to the full course Prof?
Hi, the full course will be available for view by Channel members very soon.
Any good book on cheminformatics that you would reccomend? Thank you
Good afternoon sir..
I want to join ur drug discovery online course
Hi if you click on the Join link on the main page of this TH-cam channel to be a channel member then it automatically unlocks the rest of the videos in the library.
Hi sir when this training course will start
hello professor, can you share about how machine learning can predict drug combination ?
Shall i join sir