The Workhorse of the Cell: Kinesin
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- เผยแพร่เมื่อ 14 พ.ค. 2014
- Masterpieces of microengineering, kinesins are motorized transport machines that move cellular materials to their correct locations in the cell so they can perform their functions. Kinesins have two feet, or "globular heads," that literally walk, one foot over another. Known as the "workhorses of the cell," kinesins can carry cargo many times their own size.
www.evolutionnews.org - วิทยาศาสตร์และเทคโนโลยี
The word "simple" should never again be used to describe a cell or cellular functions.
Should be cool, if in the schools we can see this video (sorry for my english)
Would be cool if the schools could see this video
@@maverickjared4931 I understand you well.
@@maverickjared4931 Don't worry about the English
How about basic structure of life lol. Imagine keep zooming in into the subatomic level. Then into quantum level. Insane.
This stuff just never ceases to amaze me! These are little entities unto themselves. All working with purpose and with specific instructions. Mind blowing stuff.
God
@@ketssa The video misportrays them as "walking".
They actually wobble and spin while moving. Most importantly, they don't always function. Many times they get stuck. The video is manmade, so it doesn't correctly show how molecules behave. It anthropomorphizes molecules - a classic mistake by people who don't understand this.
Motor proteins mindlessly move in only one direction, forced to do so by the charge gradient along the tubulin structure.
They operate a little like a magnet.
Imagine if someone made a video of a magnet "sliding like a snake" -- that would be similarly wrong.
@@ketssa Evolution.
@@Olivia-W There's no way something like that came out of nowhere by chance buddy. And that is just a small part of a whole creation that is complex, and perfectly organized.
@@Olivia-W There's is a God who Created everything, and that includes you and me. The same God who, out of love for you and me, sent His Only Begotten Son who descended from the highest heavens to this earth, to save us from our sins. He lived among us, preached the repentance of sins, the Gospel of Salvation, showed the True Love that comes from the Father, and in the end He who had no sins, took our sins upon Himself and paid the price for our transgressions in our place, gave his own life on that Cross. But on the third day he rose again. And he opened for us the way of Reconciliation with the Father, bringing to all those who truly believe in His Name and surrender their lives to Him, the Forgiveness of sins, the New Birth and Salvation. His name is Jesus Christ. He lives, and will live forever. He knows you, knows how your life has been. And the God who loves you still calls you to the redemption that every sinner who, believing in Him, finds for free. It is by true Faith in the Son of God. Repent, recognize your inability to save yourself, believe in the Gospel and confess Jesus Christ as Lord and Savior of your life. He loves you, and because He loves you, He wants to forgive you, save you and give you a new beginning, where you will no longer be alone, but from Him we have the promise that He will be with us through the Holy Spirit until the end of time.
And if we persevere and are faithful to the end, we will receive from the Lord Eternal Life, which God has promised to those who love Him.
The animation shows them walking leisurely along when in fact they are sprinting from one place to another within the cell. Mind blowing!
Pretty awesome. Imagine how many of these minute molecular machines inside of us, busily doing their intended job.
Countless trillions
"Intended" being the operative word! :)
Mind boggling. I can't imagine it.
And the Kenisen takes about 100 steps a second without falling off the tubular catwalk and doing in total darkness. Very impressive.
@@jsingh265 I write this message to you out of love! If this is too long to read check out NeedGod.net… When you observe a building you realize that there has to be a builder for it. Why? Because the building had a beginning and so the building itself is the evidence of a builder. In the same way, when you observe this universe, since it had a beginning too, it would have had to have a creator for it as well. And since there is a creator, that creator has the right to tell us what we can and can't do in his universe. Therefore, after we die he is going to have to judge us based on what we have done. Because he is good, he has rules for us to live by (rules that are actually good for us) and a punishment for breaking them after we die. That’s why he has to judge. So how good are you? God will judge us compared to perfection, not compared to other people. Here is a quick test:
Have you ever lied?
Have you ever stolen something?
Or used bad language?
Or been selfish or prideful? Since God's standard is perfection and we have done wrong, we aren't deserving of reward but punishment. That place of punishment is called hell and is somewhere you want to avoid at all costs. Will improving our life fix our problem? No, here's why:Imagine you are driving on the road and a police officer pulls you over for speeding and gives you a fine. So you say to yourself, "From now on I will not speed ever again" and you don't. But does that get rid of the fine you have already received?
In the same way in our life, even if we try never doing anything wrong ever again and just do good things, it doesn't get rid of the punishment we deserve for the bad things we have already done. In the speeding fine example, the only way to get rid of the fine is to either pay the fine yourself or have someone willing to pay the fine for you. So in the same way, either we need to take our own punishment in hell forever, or we need someone who is perfect who is willing to take our hell punishment for us. God Himself, the same God who gave us life, who we’ve rebelled against came to this earth in the person of Jesus, He lived perfectly and willingly laid down His life dying on the Cross to take the punishment for our sins. After being buried He rose on the third day and offers salvation as a gift! Trust that Jesus took your punishment for you and so be 100% certain that you will go to heaven, causing you to start living your life for Him. We are not saved from our sins because the Romans beat up Jesus and killed Him! We are saved from our sins because when He was on the tree all of your sin was imputed to Him, and all the full force of God’s wrath of His holy hatred against you and your crimes, and me, and my crimes, that as a Holy God He must pour out. He poured out on His own Son! Trust alone in Him today, and tell others about the Good news of how they can be saved through Jesus as well!! “We have more evidence for Jesus than we have for almost anybody from his time period.” Scholarly fact. My instagram is @redeemedthroughChrist if you ever need someone to contact, no I don’t need you to follow me, just send a message! I would rather tell you the hard truth than a comforting lie, the same way a doctor would tell a patient the hard truth of the reality of their disease so they will see their need for a cure/treatment. Follow truth my friend, not feelings. "Without Christianity, There Would be no Science, Cambridge University historian of science" Ronald Numbers writes. Atheism is so senseless. When I look at the solar system, I see the earth at the right distance from the sun to receive the proper amounts of heat and light. This did not happen by chance. - Isaac Newton. Taking it back to the doctor analogy, I would like to show you a disease you have called sin. The Bible (the greatest piece of antiquity in ancient history with 57,000+ manuscripts, 2200+ prophecies backed up with 27,000+ archaeological evidence, 2.7 million texts that correspond historically, geographically, anthropologically, and so on.) "The evidence for the resurrection is better than for claimed miracles in any other religion. It’s outstandingly different in quality and quantity.”-Anthony Flew. “One of the most certain facts of history is that Jesus was crucified on orders of the Roman prefect of Judea, Pontius Pilate.” (p. 162) - Bart Ehrman. “The evidence for the life, the death, and the resurrection of Christ is better authenticated than most of the facts of ancient history.” (E. M, Professor of Classics at Auckland University)th-cam.com/video/XyNseXdd260/w-d-xo.html Jesuscares.com th-cam.com/play/PLIB6yPRxh47S75U6zAX10GPfygnbBoRIw.html th-cam.com/video/b5Ogh7IDgxo/w-d-xo.html I love you so much, and God loves you infinitely more enough to die for you†
I just got a warm a fuzzy feeling for those little workers! Gotta love 'em!
Thank you for a very helpful video. This was recommended to me by my teacher!
damn that intelligent design part just came out of nowhere
Watch this entire video from Dr. Stephen Meyer: th-cam.com/video/y02a28FrMKs/w-d-xo.html
Nobody would conclude that a car evolved, because without systems and machines necessary for its function, being completely formed and working, your car never leaves the factory. Your car could be perfectly engineered, assembled, and functioning, except for the lack of a designed, manufactured, and assembled and functioning distributor. Without it, your engine would never start.
They same principle applies to living organisms. Without all the systems, and cellular machines, functioning, and in place simultaneously, the cell dies. The requirement of simultaneous functioning systems and machines, witnessed in the complexity of living cells, points to a Designer, rather than "fortuitous occurrence of accidental circumstance": cars originate from a designer who create them and require thousands of functioning and properly assembled parts for successful driving. The single cell infinitely surpasses the complexity of any car. Moreover, the Information within the DNA is biological "'computer code." Code originates from a Mind. Ask Bill Gates if any of Microsoft's computer code or devices originated by chance.
@@Pseudify Read this book (Kindle for $7 or paperback $15) by Dr. A.E. Wilder-Smith (5 earned doctorates and professional accolades a mile long, his BIO is on the back cover of the book) Book title: "The Natural Sciences Know Nothing of Evolution" www.amazon.com/natural-sciences-know-nothing-evolution-ebook/dp/B01A013NNY/ref=sr_1_1?dchild=1keywords=the+natural+sciences+know+nothing+of+evolution&qid=1587935761&sr=8-1I had the privilege of meeting him. A wonderful and gracious and humble man.
Or watch few TH-cam videos from this search result: th-cam.com/users/results?search_query=dr.+a.e.+wilder-smith
Ask any computer programmer if ANY functioning program can arise from pure chance without any intelligence or information. Microsoft and Apple pay programmers healthy salaries to ensure "chance and accidents" are eliminated from all their computer code. You won't see a programmer randomly banging away at the keyboard hoping at the end of the day that a better "more evolved" version of Windows or MacOS is the "happy accident" result. If they did that and expected a pay-check at the end of the day, they'd be fired on the spot and sued by their former employer.
The DNA of any organism is far more complex that a simple computer code. It can repair, duplicate, and read itself. The binding forces among the components of DNA do not favor any one of them binding together in any particular way, in and of themselves. Furthermore, in order to have an Amino Acid that produces life, they ALL have to be Left-Handed Amino Acids. If only one Right-Handed Amino Acid enters the chain, the Amino Acid will not produce life. (Charility is the term that refers to how polarized light refracts when shining through a solution of Amino Acids; bend to the left=L-Amino Acids; bend to the right=R-Amino Acids)
In Miller's famous experiment, he claimed to make Amino Acids in the lab using what he said were the conditions that existed on earth at the beginning. He did produce Amino Acids (using intelligence and manipulation of conditions to get a favorable result). BUT what he produced would never result in Life, because it produced both L-Amino Acids and R-Amino Acids in equal proportions. And since Left or Right Handed Amino Acids bind together with equal preference, eliminating all R-Amino Acids from a thousands long L-Amino Acids chain required for JUST ONE PROTEIN is impossible. FURTHERMORE, the Amino Acids were created in WATER and the process is reversible for each type of Amino Acid. Meaning, as Amino Acids are produced, they will reach a state of equilibrium; 50% L-Amino Acids and 50% R-Amino Acids. And since Miller did this in WATER, he knew he had to eliminate water from the process, since water is a bi-product of Amino Acid formation. Meaning, the less water exists, the more likely Amino Acids result. But the more water exists, Amino Acid formation stops, because the chemistry will bring the process to equilibrium. Bottom line: Life does not result from time, chance, and the properties of matter. Even under the favorable conditions manufactured by Miller, the chemistry does not produce Life. If it cannot occur on a DNA cellular level, it is more impossible to "evolve" on a macro-evolution level. The science says no.
@@Pseudify Hello again, David I fond an A.E. Wilder-Smith video that is not a detailed response to your question but it is no nonetheless very good. You can watch it here titled: "A.E. Wilder-Smith Interview on Dutch TV" th-cam.com/video/agV0FO4pN7M/w-d-xo.html
"damn that intelligent design part just came out of nowhere"....yes, like a boneheaded hand grenade.
Yes! I heard that and I was like, "wait, what? I thought this was a science channel, not a religious channel."
Bless you for your amazing work!
2:33 these little motors can take 100 steps per second? so the animations we see are slowed down..why not show at natural speed?
lol :D
Would you even seriously be able to SEE that?? I didn't think so
Yeh and preferably at the correct size also, this animation is very misleading
he run
Really? You do know you wouldnt be able to see it dont ya hmmm?
Lord. Your work is just amazing 😃
MIND-BOGGLINGLY COMPLEX !!!
As a physicist, my understanding is that in general random processes don’t produce order. The complexity in the cellular molecular machines is astonishing. Could random processes ever produce something this complex? Science doesn’t have an explanation.
There are good experiments and demonstrations that show order arising from random starting states based on the physical chemistry of the components and their context.
8 nano meters per second!!! WOW! This is so cool!
8 nano meters per step, 100 steps per second. That's 800 nano-meters.
It's an interesting video and it's also helpful for understanding the concept.. thank you😊😊
These are so great! Are there more! Great job I love them!!!
Absolutely marvellous
There is a problem that can only have two possible solutions. One of the answers I can clearly see is impossible and the other one I can simply not tolerate because of the implications and how it effects me personally. Which one am I going to say is correct?
You've summarized the debate perfectly.
Can you elaborate? I am interested, yet too dim to divine your meaning
BOOM
I appreciate your honesty in considering the options, Orville. Keep at it, and go wherever the evidence leads you.
Put aside, for the moment, the wonders of a single Kinesin. Now consider how to control and coordinate trillions of them? This is obviously more advanced then any air traffic control system. Vectors and triangulation algorithm's, a serious air traffic control scheduling program, avoidance handling, exception handling, multiple levels of system timers, etc. We don't talk much about timers. Timers need more press as you can't do any of this without timer primitives. Most likely some super efficient Interlock and memory primitives as well. Add to the mix, object composability, and a seemingly correct-by-construction overall design. It goes on and on. Truly boggles the mind is an understatement.
William S once you understand valency, it clicks.
1. this is an underrated comment lol Quantum Chemistry FTW
2. It's not valency, it's I N T E L L I G E N T D E S I G N
Its the polarity and sugars my friend
Comparing it to air traffic control is a false equivalency.
Air traffic control requires human intervention as well as computerized planning (also input by a human at the end of the day).
The processes in the body are completely autonomous and automatic. The laws of physics and chemistry have figured that out for us.
At most the brain signals the release of hormones to set the entire "machine" that is the human body in motion.
Absolutely. We are truly amazingly made. Blows my mind!
No, we're collections of evolved motor proteins.
This is fascinating.
There's a lot of research on bidirectional operations of various motor proteins. But I'd like to find out if bidirectionality is used in order to get cargo unstuck, like rocking a car that's stuck in mud. Anyone have info on this? Oh and by the way, goes without saying, FABULOUS animation, even five years later, still GREAT!
"The simple cell, there's nothing simple about it" Joel R
NOW THAT IS AWESOME!!! UNBELIEVABLE !!! MIND BLOWN !!!
Well you made it pretty easy for me to understand. SEEING A GREAT VIDEO AFTER A LONG TIME IN TH-cam. xo
great video!
Good video, would have be nice to understand how kinesin initially bond with protein and microtubiole, do they just hands there waiting? I've heard they have a reverse gear, which would be worth mentioning and what happens at the end, dio they get discarded or travel back to the center?
Kinesin only steps one way one step at a time, away from the centrosome. Dynein, actually shown in the video, is responsible for retrograde transport and it can take a step or two back. Look up Ron Vale UCSF for the best explanations.
Great video if English subtitle will be better! I've already learned that still English description seems difficult . But great great video, always A level!
Fascinating. I could watch this stuff all day.
Is it also intelligent design when a kinesin mutation inhibits normal functioning, causing neuronal damage or spastic paraplegia?
Malfunctioning machines are also designed.
I think I remember that if the Kinesin runs into a tube blocking it's path, it'll actually flip to the underside of the bridge and get around it that way. Would be cool to include that in the vid too.
It does kind of. It is holding on using electrostatic forces and consuming ATP each step, but when blocked it causes a shearing in electrostatic forces making it sidestep back and to the left, then forward one, back and to the left, etc. This makes it walk around until it can pass through.
It evolved this way to increase throughout.
Avery Kucan you mean it was designed that way
@@pilotavery 'evolved' ?...hahahaaa !
@@TheBlueCream yeah, I guess when you look at how dumb some people are and how little the average Joe understands about biology, maybe it does feel like we aren't involving at all as a species
@@TheBlueCream creationist spotted
Awesome!
where can i get this footage? Did you guys now any website to buy this?
That last bit! LOL! It was good up to that point.
that was hard to listen to, yea
Thank you for providing this video. It is educational and factual.
No, this is bad science. This video is just wrong on a couple of points.
@@talzhemirmrr1602which points (apart from the obviously flawed conclusion about intelligent design).
Do you have any videos on phages?
...another example of "intelligent design, engineering, and construction".
And this all happened by chance right?
Right, how did you guess? They are so pathetic materialists... What do they want to see more?
Ofcourse not
How are the Kinesins manufactured themselves? And how do they know what to carry, where to go and when?
God gave all living t hings a spirit to guide all operations in our bodies. Our god gave us a spirit so that our when we think to move our hands our spirit has our brain move our hands. When our spirit leaves our body we die.
@@danminer5343 Zues has nothing to do with Kinesins
@@vortexxsingularity Nothing could live without a spirit, and only God can provide that.
@@danminer5343 Apollo has nothing to do with Kinesins
@@vortexxsingularity God created the universe. Evolution, abiogenesis and God are all real.
Simply Extraordinarily Mind Blowing
SUPER DUPER AMAZING !!! WE TAKE OUR CELLS FOR GRANTED ~ CELL IS A WHOLE UNIVERSE IN ITSELF!
Intelligent design indeed!!!!!!!
How do you go from rain hitting a rock in a mud puddle to this cell machine?? In a TRILLION years you can't get dirt to come alive by sloshing it around. What is the answer?
If you're still interested, look up videos about chemical evolution. It's quite awesome.
Why don't you do the research to find out?
How did scientists determine the structure of the knesin?
it was discovered with video-enhanced contrast-differential interference contrast microscopy and its structure was studied using x-ray crystallography and cryo-electron microscopy
Thank you kinesin, for taking one for your homie :)
Check out the workhorse of you cells, in this animation - amazing...
At the end “Another example of intelligent design”. What?
I thought the same haha.
A pretty anti-scientific observation on the narrator's side.
Discovery Science is a religious organisation acting like a scientific one
@@spikarooni6391 it certainly seems so. Very disingenuous and inaccurate.
Explain how these buggers arrived at random
ANTI-SCIENTIFIC??? How much more from a "scientific" conclusion: "Physicist Explains Dimensions in 5 Levels of Difficulty" th-cam.com/video/3KC32Vymo0Q/w-d-xo.html
Scientist: I believe "It was always there." Skeptic: "Why?" Scientist: "Why not?" Call it P H Y S I C S
Christian: I believe "In the beginning, God created the heavens and the earth..." Skeptic: "Why?" Christian: "Why not?" Call it RELIGION
Seems that scientist position requires as much faith as does the Christian
Last words of this video: Intelligent Design. Accept it and give the Creator the credit and gratitude.
Your photo looks like tge word Allah in arabic btw. Amazing
@@thinkislamcheckmychannel - It's a guy playing a saxophone.
This is amazing
Great work by animators
Intelligent design indeed.....whether by a God or whatever other means - it certainly is incredible
How does it know where it is and where to go? where is its brain? ,who designed it ?
your DNA.
Roughly 125 seconds for a kinesin to take cargo from one end of the cell to the other. Just insane how fast this process is.
A couple of notes: a) the average cell is about .1 mm, so a circuitous path is required for a 8mm walk and b) the mention of 'intelligent design' at the end should be noted. Follow up indicated the usual meaning of that.
Why be indulgent at the end mixing fact and fiction
Jesus Smugglers
Facepalm at the end.
Owen Prescott Ugh. Facepalm after reading your comment.
+Owen Prescott
Which statement in this video did you disagree with, and upon what basis? Give the time stamp.
+Yesica1993 I think he's referring to 3:05, where the narrator attributes it to intelligent design lol
+Matt Iles
I'm sure he can answer for himself and clarify. (Though I doubt it, since it's an old comment.)
Oh, and on the basis that there are no current examples of intelligent design, and this video certainly isn't one :)
another example of the ingenuity of the Flying Spaghetti Monster
Beautiful!!
Love this ! ❤️
How does the road get built in the right direction!!!!
GPS God's Positioning System. :)
And then get recycled in a different place? It all happened instantly by Magic - according to the evolutionists. Those that actually think about the issue recognize design and purpose, NOT random and accidental.
Chemical signaling. Certain parts of the cell have certain chemical transmitters that are specific for each structure in the cell. And the cell can detect them and thus create a response system. Basically a huge series of chemical reactions. Also, the entire cell is organized in polarities. One end of the track is negatively charged while the other is positive. Certain parts of the cell will only connect with either positive or negative side, depending on the location.
Chemical signaling? So is it the sequence of amino acids that triggers the chemical reaction for the material to build the proteins?
PANDORASBOXRELEASE so is it me or has it amino acids that trigger the chemical reaction and signals for the parts needed to build a protein?
It's amazing to know that people actually think something like this came to be through time and random chance! (Talk about blind faith!)
But it is by chance (well sort of) . If you were to look at each chemical process and how everything came to be its all fundamentally by certain chemical processes affecting one another and other chemical factory (life) communicating with each other. From a human point of view this is by chance. But actually its well sort of destined to be. What I mean by this is that if you had every piece of information in the universe, every position energy momentum of every participial and so on. You can predict and get it right what will happen next. Eg the motion of nitrogen atoms in the air in a room right now appear random but actually on a fundamental level that nitrogen atom interacted with other atoms that there momentum was determined through other interactions. If you knew ever single momentum of each air molecule (and some other factors like position and environmental factors such as IR radiation ec) in the room you can predict the exact path one air molecule would take. There is no blind faith, coming up with an in falsifiable concept such as a god is blind faith it has no predictive capability and achieves nothing.
TH-cam•ACCOUNT•ENTITY yes in a way but also evolution isn’t completely random as certain traits are selected for.
Beyond words!!!
Stunning
This feels so good to see this little miracle of mother nature.😍
God*
How do Kinesins know where to go and what to do? What programs them so that they carry out their tasks. There has to be an amazing level of intelligence not just in the creation but in the moment by moment organization of Kinesins so that they show up in the right place and do the right tasks. This transportation issue in the cell seems to require not only an initial intelligent design, but a continual intelligent interaction to keep everything operating. See Job 34:14,15.
You are absolutely right because He tells us in His word:
Acts 17:28
28 ‘For in him we live and move and have our being.’As some of your own poets have said, ‘We are his offspring.’
Colossians 1:17
He is before all things, and in him all things hold together.
Doug, you asked the exact right question. As a programmer, is so obvious a program and event driven architecture going on here. Not only inside the Kinesin, but also a higher level operating system that is directing and coordinating all interactions (e.g. message passing Actor model). The question then becomes where is the network and the messages and how is that done? The microtubules would be one obvious place to look. I think people like Rubert Sheldrake and Dr. Stuart Hameroff looking at things like morphic resonance and microtubules need a lot more attention. There is so much more going on here then Darwin's jello.
this might seem a very stupid question, but how the kinesins "know" what to do, where to go, when to release the cargo, etc. if it doesn't have a nervous system itself
No, that is a good question.
Why disable embedding?
everybody gangsta till the kinesins start walkin
Only GOD knows the answer to that question. But no amount of time and chance can accidentally create the intricacies of a single living organism let alone the intricacies of the innumerable living creatures and the environments required to sustain them. It's got the signature of design written all over it!
Blessings,
chris embury
Agreed
yeah enough time can.
@@harshdutta3942 oh yeah
Fantastic
Darwin thought that cells were just a bunch of simple redundant protoplasm, had he known how complex just a tiny single cell is, then he would have doubted his own theory of evolution.
I think that, too.
it's just so goddamn CUTE.
Any intelligent designer knows that evolution is the optimal way to create.
This comment made my day
And what energies chare them to work , why they work , and more tell about automatic assembling highways how they work, and how they know that the someone is coming and we have to make it road for the wolking person ???
Like a dung beetle carrying weight beyond its own!! Amazing.
Hey, we see some comparisons with dung beetles. But the Conieson is floating around in a sphere of goo.
The microtubules are created as the transporting is occurring. It’s over the top complexity. Thank God we are alive to see it with our own eyes.
Mind blowing...How is the cargo loaded and unloaded I wonder?
dunno
On end of the track just detach the cord. Those processes are explained now more accurate here on YT.
I will praise You my God, for I am fearfully and wonderfully made!!
How about those with genetic diseases, the still-born, cancers. Hm???
How do the self assembling microtubules know where they are taking the materials?
That is presently beyond our understanding. God's designs are incredible!
@@rubiks6 May be beyond your understanding. For biochemists, this is not a mystery anymore. Search youtube to see details of microtubules assembly.
@@keerthi3086 - The question was not about assembly. The question was about destination.
Excellent
3:02 "another example of intelligent design" - wait, whot?
To level up, you need to research "irreducible complexity" in micro machines. Long story, short: The further you go, the more you learn how interwoven and interdependent everything is, the more the thought of "this can't have just happened by accident" will play in your head.
Ben Thurber , irreducible complexity is a bad argument that comes from a lack of knowledge if evolution. The mutations are random, but evolution is not. As characteristics are selected for, they build on each other until a new function is established. For example the Bactria flagellum. That fascinating molecular motor, can about through many generations. The ubonic plauge has a simper structure. It’s not a molecular Motor but may still of helped in some way which then after many generations developed more mutations that build on eachother. That’s why these complex processes exist. Remember life has had millions of years to evolve.
@@terminate5888 sorry but it seems as if you did not understand the irreducible complexity argument
Red One how so?
@@terminate5888 I try my best (: Sorry it is a very long answer ):
I think your assumption is that random mutations that do NOT possess any advantage can still survive and accumulate in the genes. And if you add 100000 of these random mutations over time you might get a useful end result, a new function that actually DOES have an evolutionary advantage?
The problem here is manyfold, but here are some points I do not understand: 1. Non useful mutations are a disadvantage as they waste energy and resources. For instance why do humans lose muscle tissue by lack of gravity?
2. If non useful mutations survive and are statistically much much much more likely than useful ones, why does our cells not have 100000 of unuseful proteins?
3. It's basically saying, that everything developed randomly, we do not even need natural selection as we do not need useful mutations! And I can never accept that 10000 of random events led to the construction of a useful structure whereas natural selection does in theory make sense.
And I think you also referred to the co-option argument (:
My problems with it are: 1. We do not only need the parts of thr motor, but also an assembly instruction, sequence and machinery that does do the assembly work itself. And all of this has to change too which is in itself a irreducible complexity problem
2. The first molecular machinary has to be developed in the first place and is OFTEN not simple and in itself subject to irreducible complexity.
Bonus point:
- In my personal experience, I do know of any (recorded) mutation that does not destroy an old functionality and does add an advantage. Except bacteria and they are "designed" to have mutations. I'd be glad to see here an example.
Wow, our God is AWESOME!
It isn't God, it is magic, chemical magic.
Who is 'your' god? A man or that man's creator?
3000+ gods, but YOURS is the ONLY one that exists. All the others can't be right. - who said that again?
@@oscarl.decarvalho7397 , don't be ridiculous its the flying spaghetti monster!
amazing
100 steps/second. Wow!
Just how the flip did we get to discovering this out?
Take a biology 101 class and you'll learn how.
Well with modern super resolution microscopy they can actually see these things walking in real time. The actual understanding of the motors and complex molecular machines in general takes years of research from multiple studies and research groups that take different parts of the protein and figure out the genes that makr the protien, then the amino acids that are formed by the DNA and hoe the amino acids are arranged in the protein. They try to find out the proteins properties and how it interacts with other proteins and moelcules, then they look at the shape the protein forms and how the amino acids interact with eachother. They perform different experiments to deduce protein function. For example they may mutate a gene that codes for a particular part of the molecular motor and then see what happens to it to figure out its function. Its quite a complex and lengthy process and it certainly isnt all covered in bio 101 like samantha says 😂. The most they tell you in bio 101 is that they mutate parts of the protein to figure out what the function was but thats barely the tip of the ice berg. Ive barely covered anything in this little paragraph.
"another example of intelligent design" just because it is complex? this is very innocent.
Wll, give a theory regarding how the kinesin was formed, how this system works inside the cell, a process so crucial that certainly life is impossible without kinesin.
Mad ?
Shouldn't the tubule be flexing up and down? Don't get me wrong, this is a fantastic visual representation, but wouldn't it be wobbling a bit?
the micro-tubule is like a million times the mass of a single kinesin
Why are the cells mindless while we, made of them, are conscious of our and their actions. Imagine you are made of trillions of ants and can't talk to any of them, and yet you know if they stopped working you would no longer exist as alive. There must be even more mystery there still hidden. Hopefully we'll never know the full story for I fear it will be nothing more than movement, and our consciousness comes from the complexity and is not a real thing other than that.
@buymebluepills That would do it!
"Of the simplest machines, a toothpick has no moving parts. Of the most complex of machines, a protein has the highest of manufacturing requirements. Given every tree on the planet and infinite time, evolution could never make a toothpick. Even incompetent engineers know that. Without totalitarian censorship and persecution, evolution would not last a month."--Joseph Mastropaolo
Complexity is not evidence for design. In fact, many objects which were designed are characterized because of it's low complexity. In the eyes of a christian for example every object in the universe has been designed by god, so you can't argue that because of the complexity it must have been designed, as low complex objects like rocks or grains of sand should also be evidence of design. That means, in a world where cells would be very simple, creationists could also present the argument of it being designed. So the argument is completely absurd and many people fail to realize this.
Amazing... Proves there's a God... The creation was no accident.
I don't know if it's _proof_ but it's a rather good demonstration.
How can evolution explain the term "masterpieces of micro engineering"?
“Intelligent design” is right.
Awesomeness, intelligent Design. There's no way all those incredibly complex nano-machines all came together at once. And one wouldn't exist without the others.
Nope, evolution. And some did exist before the others.
Some people just seem to dislike where the evidence takes them...
But most amazingly is the cell mechanism that generates the crappy music that accompanies
cellular functions. Anyway, the music makes you want to believe and the computer generated cartoon makes you want to believe. The chemical reactions occur. This is known. But how? Very unknown. That little cartoon two-stepping thing is just an animation of the most basic of steps in that particular chemical function. You can just as well apply it to any process that involves two steps.
Did the very first cell that is the ancestor of every living thing on the planet have these?
If not, how did it move things around and how did incremental mutations create something this complex?
If so, how did something that complex come together by accident?
Thought this was pretty good, until the intelligent design quote at the end. URGH.
+Phillip Parr yeah but you probably couldn't answer the question of what the scope and limits of the function consciousness is in the cosmos. You're so locked in that restrictive debate between God and No God you don't contemplate beyond that. That's not intellectual high ground. Stop breaking your arm patting yourself on the back
***** it's not really a debate. There shouldn't even be a between God and no God, because the idea of one or many Gods doesn't even make sense, and poses more questions than answers. All these people that believe in a God can't even agree which God is the right God to believe in.
Ultimately, just because something isn't yet understood, it doesn't mean that we should turn to the supernatural for answers.
+Phillip Parr ..and that explains your "URGH" reaction, how? I understand you're a stern atheist (urgh!) but the words "Intelligent design" do not imply a god - they merely imply a designer.
Phillip Parr
idiot, I'm not talking about supernatural powers. I'm talking about the nature of consciousness. Are you certain of the scope and limits of consciousness in the cosmos? Do you know what consciousness is? How are you certain of its limits? Your response indicates that you weren't even intellectually capable of grasping the questions I ask. And by the way, I'm a geology major. So try to wield the word "science" like a sword and I'll bury it deeply up your ass.
Atheism is just as dogmatic as religious. Like the religious, atheists are so obsessed with God they're not capable of comprehending existentialism outside the realm of either. Since the vast and limitless functions of the cosmos are a shrouded mystery, I am neither atheist nor religious. Atheists are self-congratulatory assholes. No thank you.
+D Lynn Very true. In some ways atheists are even more obnoxious and annoyingly fundamental (as well as just mental) then religious fundamentalists. You've actually put it quite nicely in the "level 1" part of your comment :D rgds
Wow Jesus had a solid understanding of cellular biophysics
What designed the designer? 3:05
Here from, "Still Lost I Guess, Here's a Tunnel"
"Intelligent Design" Really? And yet, them kinesins sometimes get stuck cuz of other shit and may require assistance, video destroyed it's own claim.
cars get stuck and they are intelligently designed
Everything is prone to degradation, mutation, and damage. Just like your argument destroyed its own logic. Kinesins if get stuck use other transporters help research shows, and besides all that they can conserve energy when out of work, they're not as stupidly designed as you would like to think Einstein.
Where did they find someone to imitate Richard Dawkin's voice to narrate the video? This is too funny :)
God's designs are just too awesome!
Thanks.
どうやって運搬の為に「歩行する」って行動を編み出したのかなあ
二つの軸を交互に動かす。これで歩行することができる。凄くロジカルで合理的な方法を、四足、もしくは二足歩行の生物ができるより先に(模倣の対象なしに)細胞の中で創成されていたということ
進化の不思議と言えば、生体の形態や生態のその以前、細胞内のタンパク質のあらゆる機能がどう獲得されたのか、それこそが不思議だ