Eukaryotic transcription part 1: introduction

For more information, log on to-
shomusbiology.weebly.com/
Download the study materials here-
shomusbiology.weebly.com/bio-m...
Eukaryotic transcription is more complex than prokaryotic transcription. For instance, in eukaryotes the genetic material (DNA), and therefore transcription, is primarily localized to the nucleus, where it is separated from the cytoplasm (in which translation occurs) by the entaamoeboic nuclear membrane. DNA is also present in mitochondria in the cytoplasm and mitochondria utilize a specialized RNA polymerase for transcription. This allows for the temporal regulation of gene expression through the sequestration of the RNA in the nucleus, and allows for selective transport of RNAs to the cytoplasm, where the ribosomes reside.
The basal eukaryotic transcription complex includes the RNA polymerase and additional proteins that are necessary for correct initiation and elongation.
Among eukaryotes that regulate the transcription of individual genes, the core promoter of protein-encoding gene contains binding sites for the basal transcription complex and RNA polymerase II, and is normally within about 50 bases upstream of the transcription initiation site. Further transcriptional regulation is provided by upstream control elements (UCEs), usually present within about 200 bases upstream of the initiation site. The core promoter for Pol II sometimes contains a TATA box, the highly conserved DNA recognition sequence for the TATA box binding protein, TBP, whose binding initiates transcription complex assembly at the promoter.
Some genes also have enhancer elements that can be thousands of bases upstream or downstream of the transcription initiation site. Combinations of these upstream control elements and enhancers regulate and amplify the formation of the basal transcription complex Source of the article published in description is Wikipedia. I am sharing their material. Copyright by original content developers of Wikipedia.
Link- en.wikipedia.org/wiki/Main_Page

[@tanushrih2178]

Sir I struggled with this lesson for sooooo long its actually sad, I even wrote my final exams not understanding this concept completely. I've been watching your videos for my neet preparation now and I realize how less I actually understood at school. Thanks a lot for making these free videos for a lot of concepts!!

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@nisargagowda1211]

shomu sir you are the best teacher in my life ....i loved ur teaching very much ..it made me to understand many difficult concepts tq so much

[@scottamon8908]

You are very good at lecturing, I hope you are planning to become a teacher/professor in the future.

[@anitasingh7161]

thank u very much sir u solve my problems your lectures are too good and easy to understand thanks a lot

[@tusharboxi9107]

Sir, you are my biology teacher for NEET exam ,
This was too interesting and informative keep making more informative videos liked this.

[@jaswinderkaur1684]

Ur videos are the motivational video for the students who wants to achieving their goal who r preparing for the exam .......
Very good lecture, easy to understand the concept clearity 👍👍great job sir

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@pranjalikamde9842]

It will Boost our knowlege as well as our confidence.Very clear picture about Basic and actual concept.Lot OfThanks for that.

[@bioremedyclasses7928]

Thankyou so much sir...your efforts are cost free...have a blissful life !

[@aksasobhanadaniel7351]

thank you very much sir, very well explained. this video has changed all my doubts regarding this part

[@pritirabha6943]

Thank you sir for dis video...I have saved ur videos..it really helped me a lot..I wish I could take coaching classes for net preparation...

[@th4_h0ff10]

You're doing a great job! Greets from germany! :)

[@lonesurvivor5214]

I like to see old Somu sir❤️❤️

[@shomusbiologyofficial]

Mee too

[@m.sc.partiibiotechnologysi1546]

perfectly explained....very helpfull

[@TheIansewell]

This really helped alot thank you

[@razanalshamali4384]

Thank you!
Your videos rock!!

[@chenyanting7387]

Very clearly, very helpful, Thanks.

[@anaraserikbek92]

awesomeness! thank you Suman. you actually inspired me to make my own videos on youtube in russian language, so thank you!

[@shomusbiologyofficial]

Keep on going. All the very best. Spread the word..

[@science6811]

Please make more vids..you are amazing!!!

[@syedafatimanaz8337]

sir thank you very much stay blessed with best of health Ameen

[@nisha8248]

your efforts are for free. god bless you!

[@shomusbiologyofficial]

+Nishigandha Nigam thank you.

[@Avabelieve]

Can you increase the resolution? I could barely see things written on the whiteboard...

[@arnabdas9784]

thank u sir...your videos are awesome...

[@rahatsheikh53]

A big salute to u ......sir please help me to understand post transcriptional modifications in rRNAs and tRNAs...

[@venaelmasry7214]

You are great my friend.

[@renusingh6308]

Thanks sir for such nice video this video help me a lot.

[@subratkumar3270]

Thank's sir for helping us.

[@arshinapatel8405]

very well explained!

[@anjalik2077]

it is very easy to understand all your classes
thank you sir

[@shomusbiologyofficial]

+Anjali K thank you. Glad you liked my lectures

[@woonmerngtip]

Good presentation...thanks. !

[@mssteph90210]

You are the best !!! Thank you soooo much

[@ahsanu.amalan]

Yes👍👍❤

[@urmeechandra7876]

Thank you sir for these vedios. It helps me alot for my part 3 course. I almost saved 11 vedios of yours which seems very useful to me. And I wish I could join your
coaching classes in future for NET preparation.

[@shomusbiologyofficial]

+URMEE CHANDRA glad to hear that. Please subscribe and share

[@urmeechandra7876]

Shomu's Biology yes offcourse

[@bhagatsingh7843]

Ooo

[@lifeslight3839]

thaaaaaaaaaaaaaaaaaaaaanx alot >>>> u helped me so much

[@Raptor9323]

you are born teacher man.

[@mamtaom6098]

Sir AAPne kitni sari video record ki thi ek hi din me🤔🤔..rest bi nhi Liya.. 👏👏👏 bnta h..

[@meditven]

Good explanation

[@ritugupta486]

well explained.. Thank u:)

[@shomusbiologyofficial]

Thank you. Do subscribe.

[@macadow2665]

Very nice video, thanks :)

[@unboxing0021]

Helped me alot

[@zainabfatima7952]

it's like the 1st time i've get to understand this topic this clearly out of many people who explained me this topic.Thank u sir u have explained this topic in a clear understanding way😊

[@shomusbiologyofficial]

Glad to hear that you are getting benefit from the videos

[@AsgarAli-ro7jq]

Sir...
What is replicon?

[@amitkumar-eu6zb]

it's very goog series ,,,

[@rajonkhan3280]

which writer's book I follow for this lecture

[@PUJAKUMARI-jy8nm]

thank you sir

[@alwinaanam1231]

very helpful,,,,,,,,,,,,,,,thanks

[@dak4821]

Great videos. Not as great as your aviation headset, but still great.

[@user-cu9ho5zc1j]

thank U really

[@arpanmaity4883]

Your teaching is just awsm💐💐💐👌👌

[@shomusbiologyofficial]

Thank you

[@marianareboucas6714]

Congratulations! Very good! =D

[@wafahenouda1562]

verry gooooooooooooood explanation

[@faridafghan6294]

very nice

[@deepakyadav1812]

thanks sirjiii

[@bahtuveyn5507]

Hi shomu,is there a video of your eukaryotic transcription elongation progress lesson from 3 years ago.I could not find it on your channel but you have the initiation and termination from 3 years ago.Just asking for lesson integrity.Thanks for your help

[@shomusbiologyofficial]

Yes. I didn't have elongation part

[@tuffan99]

damn you are good at explaining, i;d like to see you making more videos.

[@babitajhinkwan5949]

Sir U r liking like a pilot 👨‍✈️️😁

[@johntindell9591]

Thank you.

[@shomusbiologyofficial]

You're welcome

[@adamkavalin]

awesome!

[@prabhutadubey8803]

dna pol ka use hota hna m confused

[@ashlesha580]

nyc video

[@anuranigr3964]

Great (y)

[@anjalik2077]

very useful lecture
thanks sir

[@Wgh552]

Thanks

[@shomusbiologyofficial]

You're welcome

[@lucygomango899]

Tq u sir🙏🙏🙏

[@shomusbiologyofficial]

You're welcome

[@saimakhan8821]

Thanku sir

[@shomusbiologyofficial]

You're welcome

[@harrchhetri235]

It's blurred

[@saeedfarouq5918]

Kindly answer the comments

[@helyrbhatiya]

👏

[@user-it1ii8nk5e]

when compared to the prokaryotes u seems to be quite confused.

[@shomusbiologyofficial]

+ram prakash not confused. Speaking slowly

[@payalmaurya9978]

😏

[@rajonkhan3280]

hff

[@aveekdas1995]

shomu da.why always confused? i love the way u explain but u seem to be confused most of the time.

[@shomusbiologyofficial]

+Aveek Das it's not confusion. I deliver it slowly so everyone can understand.

[@aveekdas1995]

Shoma da. Can u send me your email. Few doubts ! Need to ask u some questions

[@kartickshaw440]

Not good concept..

[@roshnimohan8447]

very bad explaination

[@pritirabha6943]

Thank you sir for dis video...I have saved ur videos..it really helped me a lot..I wish I could take coaching classes for net preparation...

[@meditven]

Good explanation

[@rajonkhan3280]

which writer's book I follow for this lecture

[@thyabathulmufida1010]

Thank you sir

[@shomusbiologyofficial]

You're welcome

[@pritirabha6943]

Thank you sir for dis video...I have saved ur videos..it really helped me a lot..I wish I could take coaching classes for net preparation...

[@pritirabha6943]

Thank you sir for dis video...I have saved ur videos..it really helped me a lot..I wish I could take coaching classes for net preparation...