I cannot thank you enough for these videos! Your explanations are clear and very easy to follow. I am a visual learner, so your illustrations and diagrams are very helpful. Reading this material in a textbook would take hours. Your videos provide a succinct lecture on the pertinent material without all the fluff. Thank you for making this (neurobiology) PhD student's life easier!!!!!
I think it is Downstream Promoter Element instead of Upstream Control Element. And there is an extra element known as TFIID recognition element too. Please refer other books.
itz very intresting sir.... if i read my notes i would fall on to the bed ......but this is so intresting that its very easy to learn and itz worth learning.
Suman, I am afraid that I did not hear in your lecture what I wanted to hear. Would you clarify what STF do with modification histones and disabling nucleosomes? It seems to be an important part of transcription in case if we are speaking about Eukaryotas.
How TF2B interacts with RNA polymerase 2 and works as addresser molecule because without any interaction within both how TF2B address the RNA polymerase 2 ? Sir please please explain me otherwise your lecture is extremely good
Thanks for the lecture! I have a question: You say that specific transcription factors need to bind to upstream control elements and RNA Pol II, and this will recruit TFIIH and then start transcription. However, all other sources say that when TFIIH binds and phosphorylates RNA Pol, the transcription starts. The upstream elements are needed only for ENHANCING, but not activating. Which way is correct? I am confused:(
Your lectures are very simple to understand & follow sir but just one thing , can i write this in my final examination paper too? . Like in the same way you're explanation is? . Or should i refer to more books? And I may please know the books you refer to?
+Rachana Anantha Padmanabhan you can write any topic in your own words by remembering concepts from my videos. But do keep a book for a steady reference while preparing.
superb lecture in detail..thanks a lot..but can u please tell in which book can i find all these details so that i can make notes out of it..please reply soon as i have my prelim exam in 2 weeks..please please please reply..
Quick question, you said that TFIIH is the only TF that remains while the others leave. However, another video said that it is TFIIF that remains. Please let me know who is right. The other video is not as detailed as yours, and so I liked yours better. Here's the link for that video: th-cam.com/video/sSdoUnnPTm8/w-d-xo.html TIA!
I cannot thank you enough for these videos! Your explanations are clear and very easy to follow. I am a visual learner, so your illustrations and diagrams are very helpful. Reading this material in a textbook would take hours. Your videos provide a succinct lecture on the pertinent material without all the fluff. Thank you for making this (neurobiology) PhD student's life easier!!!!!
+Cee Kay glad to know that. Please subscribe and share
Thank you sir. I hope you are planning to become a professor, you are very good at explaining things. I am spending so much time in your channel.
I cant believe not that many people view your videos. This is amazing! Thank you!
a real taecher is one who make things easier for students ...... U R ONE OF THEM ..........thankyou ...
+Ujala Kashyap thank you. Glad you liked my lectures
Really Appreciate your hard work...❤️❤️❤️
Thank you
Nothing is complicated after you explain it !!THANK YOU ^_^
+Duaa A thank you
+Duaa A thank you
I think it is Downstream Promoter Element instead of Upstream Control Element. And there is an extra element known as TFIID recognition element too. Please refer other books.
thank u sir you make concept very easy to understand
You're welcome. Glad to hear that you're getting benefit from my lectures
sir i hv no words to express my gratitude towards u..
Brilliant video series! If I do well in my mol bio semester exam tomorrow, it will be because of you! :)
Thanku, Mr. Suman Bhattarcharjee ur all cocept's super and lots of more helpful my studies. .. ..
u xplained everything so clearly... really liked ur video...it helped a lot sir...
thank u soo much sir....this helped me a lot......i like ur classes....keep going...may God bless u...
+Meera Joshy thank you. Glad you liked my lectures
itz very intresting sir.... if i read my notes i would fall on to the bed ......but this is so intresting that its very easy to learn and itz worth learning.
THANK YOU SIR YOU ARE THE BEST TEACHER IN MY LIFE YOU R REALLY GENIUS.YOU JUST MADE THE WHOLE TOPIC EASY TO ME
+MANOSH ROY thank you. Glad you liked my lectures
TF2B binds to the BRE element (TF2B Recognition Element)
If I do well in Mol Gen exams,it'll be only because of you.
Thank you so much for appreciating my efforts
sir, videos are really good, the whole phenomenon is explained so well with colourful diagrams on the board, thank you.
Glad to hear that you are getting benefit from the videos
@@shomusbiologyofficial sir, could you please make a video on Recombinant DNA technology, may be a brief one
Suman, I am afraid that I did not hear in your lecture what I wanted to hear.
Would you clarify what STF do with modification histones and disabling nucleosomes?
It seems to be an important part of transcription in case if we are speaking about Eukaryotas.
Yes
What is the difference between DNA polymerase and RNA polymerase as both are dependent on other proteins or extra agencies to work on further
sir.. dts imp much..helpful for me..im msc biotech study....thnxx lot sir..really lucid n good ...complete way of undrstdd dat,,,,
TF2H mainly act as helicase
what is the difference between transcrtiption and gene regulation in eukyariotes
Thank you so ,much sir....your videos are very helpful.
Kindly discuss elongation after initiation.
How TF2B interacts with RNA polymerase 2 and works as addresser molecule because without any interaction within both how TF2B address the RNA polymerase 2 ?
Sir please please explain me otherwise your lecture is extremely good
thank you sir.
i have a doubt, what is the role of TF II F? during the initiation process, along with the removal of other GTF's, will TF II F remove?
Thanks for the lecture! I have a question: You say that specific transcription factors need to bind to upstream control elements and RNA Pol II, and this will recruit TFIIH and then start transcription. However, all other sources say that when TFIIH binds and phosphorylates RNA Pol, the transcription starts. The upstream elements are needed only for ENHANCING, but not activating. Which way is correct? I am confused:(
excellent explaination hats off sir
I got a question. In your video, what does the upstream sequence of DNA mean? Standing for enhancer or GC Box and CAAT Box?
Binding site for enhancers
Suman Bhattacharjee So enhancers are essential for both constitutive gene and regulated gene to transcribe?
Your lectures are very simple to understand & follow sir but just one thing , can i write this in my final examination paper too? . Like in the same way you're explanation is? . Or should i refer to more books? And I may please know the books you refer to?
+Rachana Anantha Padmanabhan you can write any topic in your own words by remembering concepts from my videos. But do keep a book for a steady reference while preparing.
thank you so much sir. :)
superb lecture in detail..thanks a lot..but can u please tell in which book can i find all these details so that i can make notes out of it..please reply soon as i have my prelim exam in 2 weeks..please please please reply..
+DrRitika S look for molecular biology of the gene 7th edition by watson and becker's world of the cell might be helpful
+Rohit awasthi thanks a lot..will surely look for it
Thank u so much.. For explaining in such an easy way.. 😊
+priti panigrahi thank you.
Your videos are helping alott
Thank you so much sir.
+priyanka yadav thank you. Glad you liked my lectures
EXCELLENT FOR TELANGANA STUDENTS
Suman sir u r awsome
thnku sir u alwaz help me to make my concepts clear...
sir i think bending is not minus 80 degree..that is approximately 80 degree..
thanku so much sir yur vdos are so helpful for mee tankuu so much sir
+Ayushi Singh you're welcome
u wer simply awesome
u really helped me a lot
Nice
Tq sir! For your clear explanation 💯
+Gayathri eerekar you're welcome
Thanks. It was very helpful.
You're welcome
brilliant job sir... thank u so much !!
+MSc Part 1 thank you so much.
i find it very helpful THANK U SIR
very useful to all those does not belong to the good institute as well as good int...
Thanku so much ....😀
You're welcome. Glad to hear that you're getting benefit from my lectures
Educative videos.
You're welcome
amazing lec🙏
Thank you
U r life saviour sir
Thank u so much fr such wonderful videos 🙏
Thanx a lot Sir...
Quick question, you said that TFIIH is the only TF that remains while the others leave. However, another video said that it is TFIIF that remains. Please let me know who is right. The other video is not as detailed as yours, and so I liked yours better.
Here's the link for that video:
th-cam.com/video/sSdoUnnPTm8/w-d-xo.html
TIA!
Also, is the STF mentioned here TFIIE?
TFIIH has helicase activity. TFIIF acts like a sigma subunit and so it eventually falls off.
11:40
thank you so much .....sir
thank you sir ...
It helpful...thanks..!
Bless your soul!
thank you
you're awesome!
thank yew sir...
+Avini deity you're welcome
Thanks! You're the fuckin' man, guy.
GOOOOOOOOOOOOD
Thank you so ,much sir....your videos are very helpful.
Thank you so much sir....
Thank you sir....