Understanding Drug Efflux - Small Multidrug Resistance Family - Stoichiometry and Specificity

Session Abstract:
The transporters of the SMR family catalyze multidrug and toxin efflux in bacteria, energetically driven by proton influx. Not only are these proteins interesting in the context of novel antimicrobial strategies but due to their small size, they are valuable tools for a better understanding of transport mechanisms and substrate specificity.
In the first session of the transporter webinar series, we have the opportunity to learn from two experts in the field, Randy Stockbridge and Katherine Henzler-Wildman, about their approaches and insights working with this transporter family.
PRESENTERS:
Randy Stockbridge, Assistant Professor, Department of Molecular, Cellular, and Developmental Biology (University of Michigan)
Katherine Henzler-Wildman, Professor Biochemistry, Department of Biochemistry
(University of Wisconsin-Madison)