Watching in 2024 in my second year medical school and am really surprised after getting used to him in Physiology, biochemistry and anatomy am like, what doesn't this guy know 😂 thanks alot Ninja nerd, u save our CGPAs😊
You made this topic more interesting. I was so frustrated sitting in my Clinical Bacteriology class for 3 hours lecture because I can't understand a thing. Also, I had high result in my Biochemistry exam because of your videos. You're an angel!
If every professor would be like You and explains like You do, I would not need to ever open a book. Because everything that you talk about in this video is cristal clear to me now, this is the thing I need. You give me big motivation now. Thank You very much
Zach, I passed my PANCE. Thank you very very much for all the help you and your team has provided. It is not easy for a 45 year old who was a homemaker for 20 years to get back into learning. But Thanks to you I did it.. Thanks a lot.
🎯 Key Takeaways for quick navigation: 00:20 🧬 *Introduction to Bacterial Structure* - Basic overview of bacterial structure. 04:57 🏗️ *Appendages: Flagella* - Flagella's primary function is motility. - Structure: Basal body, hook, filament. - Configurations: Monotrichus, Lophotricus, Amphitrichus, Peritricus. 08:59 🩸 *Appendages: Fimbriae vs. Pili* - Fimbriae are shorter, thinner; Pili are longer, thicker. - Fimbriae formed from bacterial chromosome; Pili from plasmid. - Functions: Fimbriae for attachment, Pili for bacterial conjugation. 18:03 🔬 *Specialized Structures: Endospores* - Endospores in Clostridium and Bacillus species. - Purpose: Resistance to harsh environments (heat, UV, chemicals). - Process: Replication, segregation, formation of spore. 21:52 🧬 *Bacterial Endospore Formation* - Bacterial endospore formation involves several steps: *- The mother DNA membrane surrounds the daughter DNA within the forespore.* *- A double-layered membrane forms around the engulfed daughter DNA.* *- Mother DNA degrades by specific enzymes.* *- A peptidoglycan layer is added between the double-layered membrane.* *- Calcium rushes in, creating a drier environment in the endospore.* *- A keratin coating is added for resistance to harsh environments.* 25:21 🧪 *Cell Envelope: Capsule and Slime Layer* - The cell envelope consists of layers, with the outermost being the capsule or slime layer. *- Capsule: Organized polysaccharide coating, acts as a virulence factor, promoting infection.* *- Slime Layer: Looser polysaccharide network, allows adherence to surfaces.* - Significance in clinical medicine: Capsules make bacteria more resistant; vaccines target encapsulated bacteria. 31:41 🚧 *Outer Membrane in Gram-Negative Bacteria* - The outer membrane is exclusive to gram-negative bacteria. *- Phospholipid bilayer with porins and lipopolysaccharides (LPS).* *- LPS structure: Lipid A (endotoxin), Core polysaccharide, O antigen.* *- Lipid A can stimulate a severe immune response.* - Gram-negative bacteria examples: Pseudomonas, E. coli, Klebsiella, Salmonella. 36:23 🧱 *Cell Wall Structure and Function* - The cell wall provides structural integrity and determines bacterial shape. *- Peptidoglycan layer composed of NAM and NAG sugar molecules.* *- Transpeptidase enzyme links glycan backbones, forming peptide chains.* *- Gram-positive bacteria have a thicker peptidoglycan layer than gram-negative bacteria.* - Cell wall components include lipoteichoic acid (stimulates immune response) and teichoic acid. 42:57 🧬 *Components of Gram-Positive Bacteria Cell Envelope* - Overview of the components of the Gram-positive bacteria cell envelope. - Gram-positive bacteria have a thicker peptidoglycan layer compared to Gram-negative bacteria. - Significance of lipoteichoic acid, a unique feature in Gram-positive bacteria. 43:52 🏛️ *Periplasm: Space Between Outer and Inner Membrane* - Definition of the periplasm, the space between the outer and inner membrane. - Presence of periplasm only in Gram-negative bacteria. - Introduction of beta-lactamase in the periplasmic space, leading to antibiotic resistance. 46:02 🧪 *Inner Membrane and Penicillin Binding Protein* - Description of the inner membrane in bacteria. - Composition of the inner membrane as a phospholipid bilayer. - Introduction to the penicillin-binding protein and its role in cell wall stability. 51:32 🖌️ *Gram-Staining Procedure Overview* - Introduction to the gram-staining procedure. - Step-by-step explanation, including fixing bacteria to a slide, applying crystal violet stain, and adding iodine as a mordant. - Insight into the purpose of the ethanol wash and the role of safranin as a counter stain. 59:16 🌈 *Gram-Staining Results and Atypical Bacteria* - Understanding the outcomes of the gram-staining procedure. - Differentiation of Gram-positive and Gram-negative bacteria based on staining results. - Brief overview of atypical bacteria that do not conform to typical staining patterns. Made with HARPA AI
Man actually you are the best. This is the 3rd year of following your lectures and you still amazes us in the level of explaining and illustrating the hard topics into pieces of cake, thanks our legend.
I can sit through multiple lectures, read the textbook AND watch all the recommended videos and answer all the recommended review questions and barely learn SH*T. but for some reason I watch one ninja nerd video and I soak up info like a sponge. You have a true gift for teaching and explaining. Thank you for putting this out there for everyone just trying to get thru Micro.
Wait, did I actually started to like microbiology... No way... That was the best microbiology video I have seen on youtube. I didn't know this channel before... I am definitely subscribing now. Thank you a lot!!!
First time running into your content, conclusion: your enthusiasm is so freaking adorable. Love seeing people passionately sharing their knowledge. You're amazing ❤️
Hi Zack, Im From Ghana. Your videos on physiology and biochemistry helped me through first and second years of medical school. The third year which will start in January will be microbiology, pathology and pharmacology. i really wish u will continue with the microbiology series
Honestly one of the best explanation in layman terms.. I am having my sister Staphycocculus aureus bacteria developed the resistance and your videos was really helpful in order to understand the complexity. Thanks alot..
Professor Zach please can you explain and make more videos about these subjects because I’m struggling:- 1-microbiology 2-Pharmacology [like the basics of pharmacology example the ANS relation with drug ] 3-General surgery 4-pathology 5-general medicine
bunch of thanks for this more clearer and detailed lecture about bacteria .. you just took more than 1hr of lecture which i partially learned for 5 mos in college and got nothing
THANK YOU SO MUCH FOR UPLOADING YOUR FIRST MICROBIOLOGY VID!!! We're waiting for other microbiology videos to be uploaded!! I can't express my appreciation
We need a video about virology and the multiplication cycles of viruses pleaasseee bec of u I passed last year’s physiology and I came back for microbiology Your videos are not just helpful, they’re so interesting to watch
You are an amazing teacher ! Thank you so much for making this make sense. Finally Im able to understand what I've been reading for weeks!!! You are a Blessing !!
Damn. You are amazing! You can teach anything, from biochemistry to medicine to microbiology. You are really amazing. Love you. And thank you so much for this beautiful video. 🇳🇬
U hv aptly kept ur channel name Ninja Nerd , indeed U R😊 It’s been ages being a homemaker bacteriology seems interesting. Thanks a ton. Please a detailed explanation on virology and bacteriology please. Also, cud u suggest any good book for microbiology. Gratitude from India
I have a test in 1.5 hours and this was a marvelous review! Thank you for the little pauses you give after asking a question, this did more for my studying than hours of reading.
okay, it's almost ridiculous how Zach can teach ANY subject and make it engaging... you guys are a blessing 💕💥🙌
Right?! if microbiology seems fun there must be some dark sorcery involved.
That's why he's NINJA🙇
lololol so reaaaal
Watching in 2024 in my second year medical school and am really surprised after getting used to him in Physiology, biochemistry and anatomy am like, what doesn't this guy know 😂 thanks alot Ninja nerd, u save our CGPAs😊
You made this topic more interesting. I was so frustrated sitting in my Clinical Bacteriology class for 3 hours lecture because I can't understand a thing.
Also, I had high result in my Biochemistry exam because of your videos. You're an angel!
If every professor would be like You and explains like You do, I would not need to ever open a book. Because everything that you talk about in this video is cristal clear to me now, this is the thing I need. You give me big motivation now. Thank You very much
Zach, I passed my PANCE. Thank you very very much for all the help you and your team has provided. It is not easy for a 45 year old who was a homemaker for 20 years to get back into learning. But Thanks to you I did it.. Thanks a lot.
HUGE congrats! The PANCE is no walk in the park. What an amazing accomplishment! 😀
Congratulations! Happy for you Mister 😊
@@NinjaNerdOfficial thank you
@@AleksandrSharashkin Thank you
You deserve it ❤ .. Congratulations 🎉🎊
🎯 Key Takeaways for quick navigation:
00:20 🧬 *Introduction to Bacterial Structure*
- Basic overview of bacterial structure.
04:57 🏗️ *Appendages: Flagella*
- Flagella's primary function is motility.
- Structure: Basal body, hook, filament.
- Configurations: Monotrichus, Lophotricus, Amphitrichus, Peritricus.
08:59 🩸 *Appendages: Fimbriae vs. Pili*
- Fimbriae are shorter, thinner; Pili are longer, thicker.
- Fimbriae formed from bacterial chromosome; Pili from plasmid.
- Functions: Fimbriae for attachment, Pili for bacterial conjugation.
18:03 🔬 *Specialized Structures: Endospores*
- Endospores in Clostridium and Bacillus species.
- Purpose: Resistance to harsh environments (heat, UV, chemicals).
- Process: Replication, segregation, formation of spore.
21:52 🧬 *Bacterial Endospore Formation*
- Bacterial endospore formation involves several steps:
*- The mother DNA membrane surrounds the daughter DNA within the forespore.*
*- A double-layered membrane forms around the engulfed daughter DNA.*
*- Mother DNA degrades by specific enzymes.*
*- A peptidoglycan layer is added between the double-layered membrane.*
*- Calcium rushes in, creating a drier environment in the endospore.*
*- A keratin coating is added for resistance to harsh environments.*
25:21 🧪 *Cell Envelope: Capsule and Slime Layer*
- The cell envelope consists of layers, with the outermost being the capsule or slime layer.
*- Capsule: Organized polysaccharide coating, acts as a virulence factor, promoting infection.*
*- Slime Layer: Looser polysaccharide network, allows adherence to surfaces.*
- Significance in clinical medicine: Capsules make bacteria more resistant; vaccines target encapsulated bacteria.
31:41 🚧 *Outer Membrane in Gram-Negative Bacteria*
- The outer membrane is exclusive to gram-negative bacteria.
*- Phospholipid bilayer with porins and lipopolysaccharides (LPS).*
*- LPS structure: Lipid A (endotoxin), Core polysaccharide, O antigen.*
*- Lipid A can stimulate a severe immune response.*
- Gram-negative bacteria examples: Pseudomonas, E. coli, Klebsiella, Salmonella.
36:23 🧱 *Cell Wall Structure and Function*
- The cell wall provides structural integrity and determines bacterial shape.
*- Peptidoglycan layer composed of NAM and NAG sugar molecules.*
*- Transpeptidase enzyme links glycan backbones, forming peptide chains.*
*- Gram-positive bacteria have a thicker peptidoglycan layer than gram-negative bacteria.*
- Cell wall components include lipoteichoic acid (stimulates immune response) and teichoic acid.
42:57 🧬 *Components of Gram-Positive Bacteria Cell Envelope*
- Overview of the components of the Gram-positive bacteria cell envelope.
- Gram-positive bacteria have a thicker peptidoglycan layer compared to Gram-negative bacteria.
- Significance of lipoteichoic acid, a unique feature in Gram-positive bacteria.
43:52 🏛️ *Periplasm: Space Between Outer and Inner Membrane*
- Definition of the periplasm, the space between the outer and inner membrane.
- Presence of periplasm only in Gram-negative bacteria.
- Introduction of beta-lactamase in the periplasmic space, leading to antibiotic resistance.
46:02 🧪 *Inner Membrane and Penicillin Binding Protein*
- Description of the inner membrane in bacteria.
- Composition of the inner membrane as a phospholipid bilayer.
- Introduction to the penicillin-binding protein and its role in cell wall stability.
51:32 🖌️ *Gram-Staining Procedure Overview*
- Introduction to the gram-staining procedure.
- Step-by-step explanation, including fixing bacteria to a slide, applying crystal violet stain, and adding iodine as a mordant.
- Insight into the purpose of the ethanol wash and the role of safranin as a counter stain.
59:16 🌈 *Gram-Staining Results and Atypical Bacteria*
- Understanding the outcomes of the gram-staining procedure.
- Differentiation of Gram-positive and Gram-negative bacteria based on staining results.
- Brief overview of atypical bacteria that do not conform to typical staining patterns.
Made with HARPA AI
Thank you goodness 😂
Wow. Thank you for sharing🥺❣️
❤
😊 thnx
Thanks
Man actually you are the best. This is the 3rd year of following your lectures and you still amazes us in the level of explaining and illustrating the hard topics into pieces of cake, thanks our legend.
I can sit through multiple lectures, read the textbook AND watch all the recommended videos and answer all the recommended review questions and barely learn SH*T. but for some reason I watch one ninja nerd video and I soak up info like a sponge. You have a true gift for teaching and explaining. Thank you for putting this out there for everyone just trying to get thru Micro.
Wait, did I actually started to like microbiology... No way... That was the best microbiology video I have seen on youtube. I didn't know this channel before... I am definitely subscribing now. Thank you a lot!!!
Welcome to the Ninja Nerd community!
First time running into your content, conclusion: your enthusiasm is so freaking adorable. Love seeing people passionately sharing their knowledge. You're amazing ❤️
Perfect timing, just about to start my microbiology portion of my class!
same here...
Same here now
same here，I just love his lecturers, absolutely amazing ❤️
Did you graduate
I'm almost 40 and I'm addicted to your videos for information; you make things interesting and explain easily. Thank you, you're a legend.
Just starting medical microbiology this year, thank you for the timely upload
Yes, your timing is perfect on this. Thanks for all you do.
I needed this. 🤩 Would love a microbiology series. Great job.
Yesssss
yes !!
Yes please!!!!!
Yess please
I don't know how to thank you Zach for all your efforts and kindness you are super ninja hero of medical students.
May I ask you if you are a medical student ?
@@omarhassan1935 I am and i agree with that. Zach is a hero for me in my studies
I didn't notice that it has already been an hour when the video finished. I was not bored. I understood the topic. Thank you very much!
I am preparing for my adat exam and I have been following your videos for a while now. You are awesome sir. Thanks a lot .
I can't believe the way you teach 😍😍 really unbelievable so so so excellent .
Why our doctors in university don't teach like this 😭😭💔
You make it a lot easier to understand these topics and it's also more interesting than just reading a textbook. Thank you so much!
You're so kind and generous to be doing this for us, for free 🥺💕
Hi Zack, Im From Ghana. Your videos on physiology and biochemistry helped me through first and second years of medical school. The third year which will start in January will be microbiology, pathology and pharmacology. i really wish u will continue with the microbiology series
What’s the duration of ‘medicine’ in Ghana
@@oghenerukevweagofure6975 6 years
Honestly one of the best explanation in layman terms.. I am having my sister Staphycocculus aureus bacteria developed the resistance and your videos was really helpful in order to understand the complexity.
Thanks alot..
While it's the start .... Happy to find every single lecture i'm stucked in ....
And i'm gonna love micro from now on thnx sir 😊
I feel like he is so smart in everything! this is a hardwork knowing everything! Thank you!!
So in love with Zach's microbiology, totally admire your passion for medicine, science and teaching!
Professor Zach please can you explain and make more videos about these subjects because I’m struggling:-
1-microbiology
2-Pharmacology [like the basics of pharmacology example the ANS relation with drug ]
3-General surgery
4-pathology
5-general medicine
Zach you are really a blessing... Naturally gifted.... Thank you
bunch of thanks for this more clearer and detailed lecture about bacteria .. you just took more than 1hr of lecture which i partially learned for 5 mos in college and got nothing
The best I have seen in this field,thank you Zach, you're very good
Bro you the best
Your lectures clear alot of confusion we be having
Hallo Zach, this is amazing! We can't thank you enough! Could you please do more about Bacteriology/Microbiology? Thank you!
Thanks Ninja Nerd. I have just completed my bachelor's degree in Biology and I enjoyed your lectures. Selfless people like deserve to enjoy.
You guys really save me during med school... thank you from Germany :)
Just starting medical microbiology, this semester. Thanks for your great teaching ❤
My Father has passed his Regards and has wished you all the very best for life for being such a great explainer.
I usually never comment on videos but this exam season you have literally saved me so thank you so much !!!
THANK YOU SO MUCH FOR UPLOADING YOUR FIRST MICROBIOLOGY VID!!! We're waiting for other microbiology videos to be uploaded!! I can't express my appreciation
watched the whole video and gained so much ... thanks from somewhere around the world :)
First time running into your content, conclusion: your enthusiasm is so freaking adorable. Love
Thank you Zach, you’re the best 🎉🎉🎉
you are saving my life man, thank you from the bottom of my heart
I LOVE how you explain everything, I´m sure God gave you that Gift, you are such a good teacher who makes science even cooler :3
We need a video about virology and the multiplication cycles of viruses pleaasseee bec of u I passed last year’s physiology and I came back for microbiology
Your videos are not just helpful, they’re so interesting to watch
What a beautiful explanation, I am enjoying this like a mystery suspense thriller movie. 🥰 Thank you 💓 for this much indepth information..
Thanks a lot my dear instructer i really love ur videos pls continue this useful course of microbiology
Zach and the Ninja Nerd Team are LEGENDS
Thanks ❤ I can’t believe I’ve watched the whole video without being bored!! I’m an actual nerd now❤
oh wow ı was just searching for ninja nerds microbiology and got sad 1 week ago now here is what ı wanted
How i wish you were my professor back when i was in college.
This was extremely helpful! I'm in micro currently and needed this! Thanks!
Thank you so much sir for teaching us in such an easy to understand way
Thank you Zach , I like your explain
you're a perfect teacher ❤
cant believe how good you are at teaching wow!
Please ninja nerd release more lectures like this of microbiology especially clinical pathology
Best timing Zach!!!! thank you!! Literally doing microbiology this sem.
Antibiotics we need a full lesson
This is my med school subject this month God bless you 🙏
I would be long gone already in the past, if not your great grat videos and explaining, thank you.
I have an exam in a month and the ONLY reason I am not stressing and struggling rn is because of this channel. Words can’t describe how grateful I am.
Zach Murphy is legendry tutor 🔥
I enjoy and understand your lectures better
You are amazing ! Thanks for all your help . You truly help me understand what I'm studying
You are an amazing teacher ! Thank you so much for making this make sense. Finally Im able to understand what I've been reading for weeks!!! You are a Blessing !!
Your help has been invaluable! I greatly appreciate the assistance you have provided me with
thank you very much for this baby steps into microbiology, really aprecciate your effort and passion
Needed this last year but a little revision doesn’t hurt
You are the a life saver. Making everything easy and fun. Thank you and your team. All the love from South Africa ❤️
This is by far my favorite channel!! You are awesome, thank you for the knowledge and dedication
I ❤LOVE ZACH. HYOUR VIDEOS ARE VERY ENTERTAINING YET EDUCATIONAL
i wish it's abeginning of bacteriology series♥️
I got an ” A “ on both biochemistry and physiology thanks to you.
Congratulations! - TG
I am starting to get the feeling that you guys will be helping me shoot to the top of my class in microbiology too.
So helpful for my micro midterm, Thankyou so much !!!👏👏
Thank u Zach passed my second mb professional examination just because of u
This is one of m my y favorite YT channels! You make everything make sense! Thank you! 😊
we all love u , ur like family to so many of us
I have taking pre reqs for the dental hygiene program and your videos help in my classes tremendously! I super super super appreciate you!!!❤
This video is perfect and engaging. Thank you so much!
Microbiology series would definitely be a great aid! Thanks zach.
Thankyou for this excellent lesson❤
Was waiting for this!
Sae
Same
Zach is just amazing. A true blessing🥰🥰
Excelent is the minimum I can say, Zach. Wonderful insights. Tx a lot.
RESPECTTTT!
I hope that one day we’ll take your steps & be able to benefit this word, big thanks from Iraq.
This is awesome …. Thank you for making it so simple to understand. I’ll be watching the rest of lessons. You’re awesome 😊
you're knowledgable and your contents are useful and practical
many thanks for your effort
Damn. You are amazing! You can teach anything, from biochemistry to medicine to microbiology. You are really amazing. Love you. And thank you so much for this beautiful video. 🇳🇬
thanks for that clear explanation from zambia
Best teacher ever
U hv aptly kept ur channel name Ninja Nerd , indeed U R😊
It’s been ages being a homemaker bacteriology seems interesting. Thanks a ton. Please a detailed explanation on virology and bacteriology please.
Also, cud u suggest any good book for microbiology.
Gratitude from India
I have a test in 1.5 hours and this was a marvelous review! Thank you for the little pauses you give after asking a question, this did more for my studying than hours of reading.
I was zero in micro actually thank u the day before the night was my saviour i studied and watched ur videos till the very end that day
You are the best professor
One word this guy is a Legend
I appreciate your videos. Hope to become a doctor in 10 years.
We are so so grateful for every video 😊
Just shut the front door with how awesome this video is!
How did you know I have a bacteriology test tommorrow? Thanks Ninja😊
You are just amazing man ,i mean like just lit🔥 kudos ! love from india 🇮🇳🇮🇳
Hey, sir!
I want to thank you for your efforts. Your videos are one of the best biology sources for me. Keep going!