Endotoxins vs. Exotoxins

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  • เผยแพร่เมื่อ 12 พ.ค. 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at:
    www.ninjanerd.org/lecture/end...
    In this lecture Professor Zach Murphy will be presenting on Endotoxins vs. Exotoxins. We will be teaching you about the differences between an endotoxin and exotoxin, in addition to the three types of exotoxins along with a common example. We hope you enjoy this lecture and be sure to support us below!
    References:
    ● Le T, Bhushan V, Sochat M, Chavda Y, Zureick A. First Aid for the USMLE Step 1 2018. New York, NY: McGraw-Hill Medical; 2017
    ● Kumar V., Mbbs, A. A. K., & Md, J. A. C., PhD. (2015). Robbins & Cotran Pathologic Basis of Disease (9th ed.). Elsevier.
    ● Mbbs, A. A. K., Md, A. L. H., PhD, & Mbbs, P. S., PhD. (2017). Cellular and Molecular Immunology (9th ed.). Elsevier.
    Table of Contents:
    0:00 Lab
    0:08 Endotoxins vs. Exotoxins Introduction
    0:33 Overview on Endotoxins
    18:13 Overview on Exotoxins
    30:09 Examples of Type I Exotoxin
    33:37 Example of Type II Exotoxin
    38:20 Example of Type III Exotoxin
    43:57 Outro: As Always, Until Next Time
    44:05 Comment, Like, SUBSCRIBE!
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    #ninjanerd #endotoxins #exotoxins

ความคิดเห็น • 124

  • @taoficmakaya1727
    @taoficmakaya1727 2 ปีที่แล้ว +44

    We need more video about bacteria 🙏

  • @hilaryenglender7521
    @hilaryenglender7521 2 ปีที่แล้ว +43

    I am a Microbiologist. and I have learnt so much from this amazing video. 🙏 😊 thanks 🤗👏👍

  • @cayla-ej8vf
    @cayla-ej8vf 6 หลายเดือนก่อน +13

    Best videos ever... I can't even express this enough. I hope you know how good you are and how many people you help.. thank you...

  • @bushrakhan2615
    @bushrakhan2615 2 ปีที่แล้ว +13

    Can't thank you enough for this I was about to start this topic today so happy to see this video posted

  • @joshbilly5090
    @joshbilly5090 ปีที่แล้ว +5

    I tested positive for HSV after having a horrible outbreak, and felt the same way you described in your interview. Listening to you share your overcoming experience gave me the glimmer of hope I needed to hear. I am glad that there are people like you out there who just want to help other people who are struggling with the same issues. Your words gave me the courage I needed to hear today to know that it's ok. I can still be myself and now I'm enjoying my life the way I am supposed to. it is a blessing i came across you drotue channel

  • @Medic81
    @Medic81 ปีที่แล้ว +1

    These lectures are so high quality,. They are great supplemental material for -paid- third party companies who teach STEP1. I will always be a Ninja Nerd. Thanks Zach

  • @Tarteel97
    @Tarteel97 2 ปีที่แล้ว +2

    This video was released on my birthday😍 you did amazing as usual! we appreciate you so much

  • @kimberlygaray8497
    @kimberlygaray8497 ปีที่แล้ว +1

    Im currently in Pharmacy School learning about antibiotics/bacterial resistance. THIS HELPED SO MUCH. THANK YOU

  • @lavender-ocean4449
    @lavender-ocean4449 2 ปีที่แล้ว +4

    This video is fascinating to me both as a nursing student and someone who suffers from mast cell activation syndrome. thank you so much for this amazing channel!

  • @alialsyaghi28
    @alialsyaghi28 2 ปีที่แล้ว +3

    pleaseeeeeeeeeeeeeee, continue this playlist for other bacteria🙏🙏
    you're my life savior

  • @sibuleleshude3366
    @sibuleleshude3366 6 หลายเดือนก่อน

    Thank You so much ninja nerd team 🙏♥️ you have no idea how many students you are helping around the world ,and you do that effortlessly

  • @gracesheilamariellemorcill4395
    @gracesheilamariellemorcill4395 2 ปีที่แล้ว +2

    Very good explanation and thank you for making this video , such a big help to understand clearly about Exotoxin and Endotoxins.❤️

  • @jasonkimball3206
    @jasonkimball3206 2 ปีที่แล้ว +1

    Beautiful!! I have been reading lots of studies utilizing endotoxin lately!!

  • @charlyrevels1341
    @charlyrevels1341 2 ปีที่แล้ว +5

    Oh man!! To say thank you simply doesn't seem enough!! Deep into my MLT program and as a hybrid student (in person only for labs) this particular course has been a bit of a struggle. Loving this so much! I swear by my near straight A's in my biology and hematology classes because of Ninja Nerd! Thank you!! I agree with below, media lesson (though I have that down) and biochemical testing?? I make my own color coded picture page notes for immunology because of these.

  • @youreworthyourweightinavoc7189
    @youreworthyourweightinavoc7189 2 ปีที่แล้ว +2

    This was so good but I think I'm gonna have to watch it multiple times to actually properly understand and retain it!

  • @thalysvandenbossche6542
    @thalysvandenbossche6542 2 ปีที่แล้ว +9

    I randomely stumbled onto your video sir. I have no microbiology background whatsoever ( i actually study business) but let me tell you that I loved every single minute of your video and learned a lot from it. It took me some time understanding the concepts you explained ( been on the video for over 3h, had to look up definitions that you probably thought were already understood by your viewers but weren't to me ) but you made all of it very clear. You are very eloquent, smily and invested and I thank you enormously for this video. Looking forward to watching more of Ninja Nerd. (not right now though bc it's 2am and I'm exhausted). Keep it up

  • @m_qv
    @m_qv 2 ปีที่แล้ว +1

    thank u , i wish u could continue this playlist soon

  • @Thegeekymedico
    @Thegeekymedico 2 ปีที่แล้ว +1

    What a timing, I just finished reading this topic 😍

  • @universeusa
    @universeusa 2 ปีที่แล้ว +2

    This is an amazing journey through the human body. 👏👏👍👌🙏

  • @agfpv
    @agfpv 9 หลายเดือนก่อน

    Its really comprehensive and amazing video about toxins.

  • @gospursgo9099
    @gospursgo9099 2 ปีที่แล้ว +2

    Thank you Master Ninja! 💓💓🥺🔥

  • @MD-2101
    @MD-2101 2 ปีที่แล้ว +1

    You are feeling the mechanism of bacteria Professor, we just study it(
    Thank You very much

  • @lisa-rouletlawfirm9307
    @lisa-rouletlawfirm9307 2 ปีที่แล้ว +1

    This is awesome. Thanks so much!

  • @cabdinaafacxaashi3176
    @cabdinaafacxaashi3176 2 ปีที่แล้ว +2

    Thanks my dear lecturer i like how u explain

  • @yahyeabdullahihassan2294
    @yahyeabdullahihassan2294 ปีที่แล้ว +2

    Very interested in this course so please try to put more videos about microbiology

  • @raghadsy3613
    @raghadsy3613 4 หลายเดือนก่อน +1

    Amazing explanation😍😍
    Thank you💙

  • @dr.asadabbas6965
    @dr.asadabbas6965 2 ปีที่แล้ว +2

    Badly needed ❤️

  • @warankaja2910
    @warankaja2910 2 ปีที่แล้ว +2

    Thank you
    Please add more videos🙏🙏

  • @tadelleyohannes9400
    @tadelleyohannes9400 8 หลายเดือนก่อน

    Wonderful lecture 👏👏👏

  • @dayanarosaarciarodriguez8581
    @dayanarosaarciarodriguez8581 ปีที่แล้ว

    YOUR ARE THE BEST DOCTOR EVER

  • @ssims373
    @ssims373 2 ปีที่แล้ว +1

    AMAZING, THANK YOU VERY MUCH!!!

  • @aayushbatra1147
    @aayushbatra1147 6 หลายเดือนก่อน

    BEST TEACHER EVER
    THANKYOU ZACH❤❤❤❤❤❤

  • @joylawrence6481
    @joylawrence6481 2 ปีที่แล้ว +2

    Lol... I'm not even in school. Just love your teaching! You really rock!

  • @anchitaparnami2470
    @anchitaparnami2470 2 ปีที่แล้ว +1

    You are just too perfect 💖

  • @debabanighosh4950
    @debabanighosh4950 ปีที่แล้ว

    Very nice explanation.
    Can you kindly make a video on LAL test.

  • @whitescpdr
    @whitescpdr 2 ปีที่แล้ว +2

    Still waiting for the whole series on individual bacteria, viruses, and so on. :)

  • @dileepkaiprath2374
    @dileepkaiprath2374 2 ปีที่แล้ว +1

    Sir please make vedios on immune response in tissue damage....or injuries to muscle, nerves etc

  • @asadbeksultonov6974
    @asadbeksultonov6974 2 ปีที่แล้ว +1

    THAT was GREAT. Thank uuu!!!!

  • @user-mx3vh4jo8f
    @user-mx3vh4jo8f 10 วันที่ผ่านมา

    Thank you so much , you are the best , we are looking for more vid.s about bacteria ❤

  • @Saakkyybb
    @Saakkyybb 2 ปีที่แล้ว +1

    Just in time 😍

  • @drvicktor7340
    @drvicktor7340 2 ปีที่แล้ว +1

    Podrías hacer un vídeo acerca de temblor neurológico?

  • @hamnomhamad3578
    @hamnomhamad3578 9 หลายเดือนก่อน

    fascinating

  • @shivanishivani4705
    @shivanishivani4705 2 ปีที่แล้ว +1

    please sir make all topics video's...i need it so much.

  • @anisali9331
    @anisali9331 2 ปีที่แล้ว +1

    Informative

  • @salamsami2973
    @salamsami2973 2 ปีที่แล้ว +1

    Thank you 💖

  • @SG-ot4uc
    @SG-ot4uc ปีที่แล้ว

    Pleaseeee We need more videos for microbiology about viruses and fungi 🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻

  • @abebedejene2459
    @abebedejene2459 ปีที่แล้ว

    we Ethiopian love you so much! you are really number one lecturer for us! my lord God bless you to eternity! once in your life we beg you to come to Ethiopia and see you while you are giving lecture face to face!!!! let God give you 1000 years to live on earth

  • @gamzedas1154
    @gamzedas1154 2 ปีที่แล้ว +1

    just love it .İ wish you woluld have a fungi video also

  • @Tharu204
    @Tharu204 ปีที่แล้ว

    Thank you so much

  • @arvindvignesh4184
    @arvindvignesh4184 2 ปีที่แล้ว +2

    thankyou bro...

  • @tchkbty7489
    @tchkbty7489 ปีที่แล้ว +2

    GEM OF MEDICINE LEARNING.

  • @MohammadRezaKhoshnam
    @MohammadRezaKhoshnam ปีที่แล้ว

    Thanks a million

  • @m_m786
    @m_m786 2 ปีที่แล้ว +2

    Great ❤️👍

  • @Sandstorm9562
    @Sandstorm9562 4 หลายเดือนก่อน

    What about techioc/lipoteichoic acids in the cell wall of Gram positives? Granted they are not LPS but they do produce a similar cytokine cascade that can result in shock

  • @sawantiparang6660
    @sawantiparang6660 ปีที่แล้ว

    Sir,i eagerly need ur notes

  • @akhilporanki8498
    @akhilporanki8498 2 ปีที่แล้ว +2

    You are the best.....

  • @shohruhbekmirabijonov
    @shohruhbekmirabijonov ปีที่แล้ว

    Thank you very much

  • @isabellaoliveira5711
    @isabellaoliveira5711 6 หลายเดือนก่อน

    Thank you ❤❤❤❤❤❤

  • @ultimatefocus5918
    @ultimatefocus5918 2 ปีที่แล้ว +1

    thanks a bunch.

  • @zuhairyassin505
    @zuhairyassin505 2 ปีที่แล้ว +1

    will you please name a textbook you have read to prepare this video i want to know more about the mechanisms of pathogenicity

  • @nihalkhan2541
    @nihalkhan2541 2 ปีที่แล้ว +1

    Sir can you please share the videos about making solutions * molarity * ppm *

  • @RTBos194
    @RTBos194 ปีที่แล้ว

    8:50 Does the stimulation of the hypothalamus leading to fever also have something to do with thyroid hormone release, since they are responsable for thermogenesis and are stimulated by the hypothalamus?

  • @becherkapuka1405
    @becherkapuka1405 2 ปีที่แล้ว

    Thanx very much NINJA NERD

  • @alsetabwsin4531
    @alsetabwsin4531 ปีที่แล้ว

    Can U make videos about general pathology please.
    🌸

  • @somebody5126
    @somebody5126 หลายเดือนก่อน

    Thank you

  • @aikaterinantoutsouli3191
    @aikaterinantoutsouli3191 2 ปีที่แล้ว +1

    I have a naive question. Can endotoxin tolerance be caused by a sublethal bacterial dose?
    Thank you in advance

  • @amalomer7466
    @amalomer7466 ปีที่แล้ว

    U r the most aaaaaaawesome teacher everr!!!!

  • @maseAfttgws12
    @maseAfttgws12 ปีที่แล้ว

    Thank you son much

  • @muradsultanov8321
    @muradsultanov8321 ปีที่แล้ว

    Hi there! Just out of curiosity, wanted to clear something. At 31:58 you mentioned that a couple of these cytokines increase the production of the prostacyclin PGE2 and so on so forth. My doubt is that (based on a cursory research) is that PGE2 and prostacyclin are different substances so am I misinterpreting something? Thank you! As always, love your videos. My need for them for medical school is absolutely essential.

    • @shivi733
      @shivi733 10 หลายเดือนก่อน +1

      prostacyclin (PGI2) has a regulatory role within the cardiovascular system, where it promotes vasodilatation and also inhibits platelet aggregation (anti-thrombotic), Also being an important inflammatory mediator.
      PGE2 is a direct vasodilator as it acts on smooth muscle to cause dilation of blood vessels. Also inhibits platelet aggregation and suppresses T cell receptor signaling and proliferation, and may play a role in resolution of inflammation.
      PGI2 exerts its actions on renal function by inducing vasodilatation whereas PGE2 also has a direct action on tubular function.
      Though it's been an year since you asked, hope it helps 🙃

  • @Ahmed99mo
    @Ahmed99mo 2 ปีที่แล้ว +1

    The best

  • @user-dn8fk3mw8i
    @user-dn8fk3mw8i ปีที่แล้ว

    thank you thank you thank you

  • @zia735
    @zia735 2 ปีที่แล้ว +1

    King in medical sciences

  • @medicalcarehealth
    @medicalcarehealth 2 ปีที่แล้ว

    The way you say beautiful :D Gorgeous mind!

  • @amalomer7466
    @amalomer7466 ปีที่แล้ว

    Thank you maaaannnnnnn

  • @sarangshoro911
    @sarangshoro911 ปีที่แล้ว

    Beautiful ❤️🥰

  • @abebedejene2459
    @abebedejene2459 ปีที่แล้ว +1

    I'm confused with Lipid A and polysacharides component of lipopolysacharides. lipid A is pathogenic not immunogenic but polysacharides are immunogenic but not pathogenic

  • @RUYINAETENGsMEDICDIARY
    @RUYINAETENGsMEDICDIARY 2 ปีที่แล้ว +1

    You are too good!😪

  • @GetinetAmha
    @GetinetAmha 6 หลายเดือนก่อน

    Thanks much,from 🇪🇹 Ethiopian

  • @drabdirahmanibrahin6021
    @drabdirahmanibrahin6021 2 ปีที่แล้ว

    Thanks

  • @lillianotuokwu5800
    @lillianotuokwu5800 ปีที่แล้ว

    great🥰

  • @rainyday6790
    @rainyday6790 ปีที่แล้ว

    Genius

  • @yasinsahal4703
    @yasinsahal4703 2 ปีที่แล้ว +1

    Microbiology. Is the basic of Human equipment in the front line of defence.
    Should learn, practice you will be in the front line human defence line.
    I wish that younger generations concentrate in learning.
    please follow-up the scholarship of this field and physiology.

  • @Amarboult
    @Amarboult 2 ปีที่แล้ว

    WE LOVE YOU ... ❤❤❤❤❤❤

  • @nihalkhan2541
    @nihalkhan2541 2 ปีที่แล้ว +2

    Please cover the solutions in chemistry 😔

  • @user-vt4ec7tk9i
    @user-vt4ec7tk9i 2 ปีที่แล้ว +1

    We wait more videos in microbiolog

  • @biologygeneandbiochemistry1654
    @biologygeneandbiochemistry1654 2 ปีที่แล้ว

    Tnx Me zach and robbbb🙏🌹

  • @folasadehungbo9150
    @folasadehungbo9150 2 ปีที่แล้ว +1

    This is wow

  • @avishikajoshi4798
    @avishikajoshi4798 2 ปีที่แล้ว +1

    type 2 exotoxin just flew through my head

  • @TP-mv6en
    @TP-mv6en ปีที่แล้ว

    Do cytokines cause fever and vasodilation the same way histamines do?

  • @iiazoz4ever291
    @iiazoz4ever291 2 ปีที่แล้ว +1

    MORE MICROBIOLOGY VIEOES WILL BE SO GOOD FOR SPECIES OF THE COMMON FAMILES

  • @tmdrkthennakoon7491
    @tmdrkthennakoon7491 2 ปีที่แล้ว

    Wow thanx

  • @christinadejean5703
    @christinadejean5703 ปีที่แล้ว

    Is streptolysin leukocidin from Strep pyogenes or S. aureus?

  • @bobblob4477
    @bobblob4477 7 หลายเดือนก่อน

    Your literally so cool

  • @wassimmansouri6015
    @wassimmansouri6015 2 ปีที่แล้ว +1

    🔥🔥🔥🔥🔥cool

  • @brittophone6219
    @brittophone6219 2 ปีที่แล้ว

    I love u 😭😭❤️

  • @christinashawgo6510
    @christinashawgo6510 ปีที่แล้ว

    Lipid A-- is that the same thing as Lp(a)??

  • @user-eb3qz9zm3o
    @user-eb3qz9zm3o 2 หลายเดือนก่อน

    sir we need mycotoxin video in complete explain

  • @Doctony99
    @Doctony99 ปีที่แล้ว

    Why Chlorine goes out from the enterocyte to the lumen?
    I knew that the concentration of chlorine is Lower in the enterocyte and Higher in the lumen

  • @yasinsahal4703
    @yasinsahal4703 2 ปีที่แล้ว

    Should you learn Microbiology deeply
    shall lead to becoming , you shall the frontline of all possibilities to control many Microbes in diseases controls.

  • @DollyDu_mybest_barbie
    @DollyDu_mybest_barbie 2 ปีที่แล้ว +2

    Amazing explanation love from india 🇮🇳❤️