Specific (Adaptive) Immunity | Humoral and Cell-Mediated Responses

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  • เผยแพร่เมื่อ 10 ม.ค. 2025

ความคิดเห็น • 173

  • @halqthedarktemplar
    @halqthedarktemplar ปีที่แล้ว +156

    To add a bit to the cell-mediated response for people reading the comments, the infected cell presents the antigen via the MHC-I (instead of the MHC-II of the APC cells) and the T-killer lymphocyte uses the CD8 receptor for that antigen

    • @naylacalvin2507
      @naylacalvin2507 9 หลายเดือนก่อน +4

      Thank you it was actually helpful

    • @BirhanuChalie-d7n
      @BirhanuChalie-d7n 8 หลายเดือนก่อน +1

      Fantastic lecture and comments.

    • @zizojaezekeom3565
      @zizojaezekeom3565 7 หลายเดือนก่อน +1

      But T8 lymphocytes need T4 lymphocytes so how did T4 lymphocytes get activated if they don't recognize CMH1

    • @Charles-uk6ur
      @Charles-uk6ur 6 หลายเดือนก่อน +2

      @@zizojaezekeom3565 well the macrophage has MHii that presents the antigen,the MHii and is recognised by cd4.while the affected cell has MH i that it presents the antigen with and is recognised by cd8 in short
      macrophage MHii - cd4
      affected cell MHi - cd8

    • @saniyaiqbal
      @saniyaiqbal 4 หลายเดือนก่อน

      actually mhc1 attaches with cd8+ and the antigen which is represented binds with TCR

  • @chefmittens3056
    @chefmittens3056 2 ปีที่แล้ว +74

    This was insanely precise. I love that you follow such a linear path for something involving a lot of steps at once. Seriously thank you thank you thank you. I've watched a lot of good videos on immunity but yours was the only one to truly make it fully understandable.

    • @SiebertScience
      @SiebertScience  2 ปีที่แล้ว +5

      Thanks so much for the kind words! Glad you found it helpful.

    • @MoodSwing-x1s
      @MoodSwing-x1s ปีที่แล้ว

      Yes, this is so true thank you😊

  • @annguy5563
    @annguy5563 10 หลายเดือนก่อน +7

    This is so amazing, you explain what my 3 hours lectures couldn't in 10 minutes.

  • @charlespolino
    @charlespolino 7 หลายเดือนก่อน +11

    Can't begin to express how excited I am to have come across your channel! 60 slides all explained in one amazing video, and everything just clicked in my head. Thanks Siebert!!

  • @TiaDimi
    @TiaDimi ปีที่แล้ว +7

    I have been researching this topic over the past week for an assignment, struggling to find anything as clear and helpful as this video by a mile. This video literally feels like the best video on the whole internet for explaining B cell and T cell functions and specific immune responses in general. The detail is perfect, the whole video flows. Thank you so much, I really appreciate your work!

  • @AnaMayorga-x9l
    @AnaMayorga-x9l หลายเดือนก่อน +2

    You are definably not a good actor, but an amazing teacher. love the ways you show us how things work and every time I am in a new chapter at school I look for your videos before I read the book to have a precise comprehension of what the book talks about.. Once again THANK YOU for your videos

  • @puneet1173
    @puneet1173 3 ปีที่แล้ว +53

    Thank you so much. I have spent hours looking for videos to help me on this topic and now you have made it crystal clear in my head. Please continue to make more videos they help so much

    • @SiebertScience
      @SiebertScience  2 ปีที่แล้ว +3

      Aw, thank you for the comment! Glad it was helpful!

    • @SyenPie
      @SyenPie ปีที่แล้ว +2

      EXACTLY. This was by far the best video I've found on this topic, presented in such a CLEAR and organized way! This man truly has a gift for teaching.

  • @fimpero994
    @fimpero994 7 หลายเดือนก่อน +19

    I've been trying to get my head around this topic for months now and I stumbled across this video, ive never heard it explained so well and so precisely yet in a way so easy to understand. You're an extraordinary teacher, THANKS!

  • @flygirlkc
    @flygirlkc 3 ปีที่แล้ว +14

    Thank you for the "clear as glass" explanation!

  • @wachimingoxd
    @wachimingoxd 4 หลายเดือนก่อน +2

    My god, what a crystal clear explanation for such a convoluted concept, spent the whole afternoon trying to understand the humoral response until I came across your video, many thanks!

  • @tiffany6376
    @tiffany6376 3 ปีที่แล้ว +10

    I got frustrated learning about immune system, but your video is truly a big help for me to understand it better. Hopefully u will continue making new videos cause I gonna be a big fan of your

    • @SiebertScience
      @SiebertScience  3 ปีที่แล้ว +2

      Glad it helped! I plan to keep making more videos!

  • @jennyrios9535
    @jennyrios9535 ปีที่แล้ว +3

    Reviewing my Physiology notes to take my TEAS exam. I looked through so many videos that were either too complex or too simple. This was perfect! Loved the artwork and the clean separation of processes. Thank you!!!

    • @SiebertScience
      @SiebertScience  ปีที่แล้ว +1

      You're welcome! I'm glad you found it helpful.
      Yeah, it's hard to find resources at the right level for a lot of this stuff.

  • @shenglor9913
    @shenglor9913 หลายเดือนก่อน

    This is the best explanation everrrr. I couldn't piece them all together until now.

  • @TheTiss1982
    @TheTiss1982 10 หลายเดือนก่อน

    This man needs a medal for this breakdown! I’m passing this exam! Talk about confidence he just gave me

  • @mulukenm268
    @mulukenm268 10 หลายเดือนก่อน +3

    What an attractive and genius way of presenting!! Please continue doing it for other parts of pathology and physiology. You made the subject matter very edible 😀😀😀

    • @SiebertScience
      @SiebertScience  10 หลายเดือนก่อน +1

      Thanks! I plan to keep making videos 👍🏼

  • @DestineeMadrigal
    @DestineeMadrigal ปีที่แล้ว

    Nursing student here! Thank you so much for these videos!! You are a hero!

  • @AnaMishu
    @AnaMishu 9 หลายเดือนก่อน +1

    I always watch your videos before reading a textbook bc most of the time textbook seems very complicated, then I do my quizz assignment with ease

  • @ratanraj743
    @ratanraj743 3 ปีที่แล้ว +3

    You are wonderful ... clear and crisp ... wish youtube present u to the needful learners in the manner how our cells present the antigens for betterment of body :)

    • @SiebertScience
      @SiebertScience  3 ปีที่แล้ว

      Thanks! I hope TH-cam listens to your advice, haha! :)

  • @sarahlee3100
    @sarahlee3100 ปีที่แล้ว +1

    Please continue making these videos. Once I learned about your channel, I can't stop watching them to learn more! Very concise and easy to digest diagrams (they are also very cute) Thank you so much

    • @SiebertScience
      @SiebertScience  ปีที่แล้ว

      You're welcome! I plan to keep making them!

  • @zygridollero5479
    @zygridollero5479 ปีที่แล้ว +2

    Thank you so much for doing this! I was having a hard time reading about this topic on my own. It made so much sense :D

  • @mondelwane8592
    @mondelwane8592 ปีที่แล้ว

    I wish you were making videos 4 years ago, my goodness man you are a life saver

  • @emersongill8501
    @emersongill8501 10 หลายเดือนก่อน

    I'm a very visual learner and the way you drew it all out and separated the different processes! thank you for finally helping my brain understand this topic :) If I get an A on my exam today I can thank you!!

    • @SiebertScience
      @SiebertScience  10 หลายเดือนก่อน

      Glad the videos were helpful. Let me know how you did on your exam!

  • @Lilacblossom990
    @Lilacblossom990 10 หลายเดือนก่อน +1

    The best and clearest presentation !

  • @johnaghogho2435
    @johnaghogho2435 2 หลายเดือนก่อน

    This was every thing I needed... Thanks for being available to help out

  • @karl_fischer
    @karl_fischer ปีที่แล้ว

    I have a class test in 4 hours and now I am fully confident that I'll ace that! Thank you.

  • @user-ok7vn5eu9j
    @user-ok7vn5eu9j 6 หลายเดือนก่อน

    I watched several videos from other people about this topic, and I was 😵‍💫 until I found yours. Your video is GREAT, and I just subscribed. Thank you !!!

  • @tajharelstewart5854
    @tajharelstewart5854 2 หลายเดือนก่อน

    Another great video, I love this guy. So smart and explains everything so thoroughly and easy to understand 10/10 teacher

  • @heatherkrn5200
    @heatherkrn5200 2 ปีที่แล้ว +1

    This is the most helpful video I have seen on the interaction within the adaptive immune system. Thank you for such a clear explanation

  • @ddamme05
    @ddamme05 2 ปีที่แล้ว +2

    I'm not a Bio major but this is probably the best video explaining anything ever. Helps me understand research I'll have to read for my extra-credit assignment. Thanks!

    • @SiebertScience
      @SiebertScience  2 ปีที่แล้ว +1

      Best video explaining anything ever???
      What a great compliment! I appreciate it!

  • @quesiachagas5446
    @quesiachagas5446 หลายเดือนก่อน

    I love your videos, and I always study for class with you. THANK YOU!!!

  • @alperbulut1267
    @alperbulut1267 ปีที่แล้ว

    i didnt had a problem with focusing on your lecture. That's rare for me thank you for the video

  • @hollyweselowski7442
    @hollyweselowski7442 2 ปีที่แล้ว +1

    thorough and helpful, im an NP student and this was SUPER helpful !

  • @haileyellingson6318
    @haileyellingson6318 2 หลายเดือนก่อน

    So helpful in helping me remember all the cells and their functions! Thank you!

  • @GiftVingula-g5d
    @GiftVingula-g5d 2 หลายเดือนก่อน

    This is amazing explanation ever held

  • @darianleduc
    @darianleduc ปีที่แล้ว

    Thank you so much! Adding the etymology of the cell and biochem names is super helpful

  • @jo_lenin8990
    @jo_lenin8990 8 หลายเดือนก่อน

    Super cool video. Thank you so much. You make it straight forward, interesting and deep at the same time. Best doctor here!

  • @stephaniemiller5165
    @stephaniemiller5165 9 หลายเดือนก่อน

    I
    Spent a week trying to figure this out and u explained it in a few minutes. You are truly a teacher indeed. Can you couple this with the Mac 1 and two? Omg you are good. I have hope now of passing this section of the exam tomorrow!

  • @laurenbaron6820
    @laurenbaron6820 2 ปีที่แล้ว +1

    Thank you so much! Very helpful video. Love the pictures made it much more clear :)

  • @paulthomas281
    @paulthomas281 8 ชั่วโมงที่ผ่านมา

    Vous êtes un vrai maître. Merci beaucoup!

  • @Jarh9999
    @Jarh9999 2 ปีที่แล้ว +1

    thank you sooooooooo much this clicks so well now

  • @chrissvitreoushumour
    @chrissvitreoushumour ปีที่แล้ว

    awesome explanation. you connected the processes of cell-mediated and humoral immunity really well

  • @Fatma-kl9lp
    @Fatma-kl9lp 3 หลายเดือนก่อน

    You made learning so much fun. Thanks a lot!

  • @chrisandarianna1583
    @chrisandarianna1583 3 หลายเดือนก่อน

    Bro, THAAAAAANK YOU! I was not understanding this until I saw your video.

  • @cbri1621
    @cbri1621 ปีที่แล้ว

    Your videos have single handedly taught me all of the systems that we need to know for the MCAT! I never took anatomy as its not required for us and when I started studying I had regrets on not taking it, but man your videos on the immune system, digestive, respiratory, circulatory and kidneys have literally taught me everything!!! Your videos are so well put together and so easy to follow I hope TH-cam pays you a million dollars a year for your services :)
    Question about the immune system: So what is the difference between MHC-II and MHC-I? Are MHC-II's only present on macrophages?
    Seriously thank you x 1000 and I hope to use your videos throughout medical school once I make it there :)

  • @jodifarias9757
    @jodifarias9757 5 หลายเดือนก่อน

    So clear and beautifully illustrated. Thanks

  • @allround8771
    @allround8771 3 ปีที่แล้ว +3

    I've been watching a couple of videos on the Immune System and I could easily admit that you're the Phil Jackson of Immunology.
    Well, Phil Jackson with a touch of DiCaprio (nice fake acting lol). You've mastered the act of transferring knowledge.
    Thank you!!!

    • @SiebertScience
      @SiebertScience  3 ปีที่แล้ว +1

      Hey, my students tell me my acting is improving! But they’re probably just being nice...
      Thanks for the comment!

  • @elle3947
    @elle3947 2 ปีที่แล้ว +3

    Took me so long to understand until this short video , so clear :) thanks

  • @marthaschurr7827
    @marthaschurr7827 ปีที่แล้ว

    Great video, and such beautiful visuals

  • @mollygrigg7005
    @mollygrigg7005 9 หลายเดือนก่อน

    I watched the lymphatic system video and now this … and I want to watch the blood one next. For the very first time I’m finding human body systems fascinating. Never had such a great teacher before. I might have gone into medicine if I had had videos like this in my younger life!
    Now I’m going to use them to teach my kids!

    • @SiebertScience
      @SiebertScience  9 หลายเดือนก่อน

      Aw, thanks for the kind words! Best of luck with homeschooling anatomy this year!

  • @akeminnocentosagie5901
    @akeminnocentosagie5901 ปีที่แล้ว

    You have definitely help and educate me so so much with your videos. You are the best with the You analyses and make it look very simple to understand. Thank u so much.

  • @arnabray3662
    @arnabray3662 2 ปีที่แล้ว

    Thank you so much for such amazing explanation. Definitely gonna nail this topic tomorrow

  • @carlapaperdoll
    @carlapaperdoll 8 หลายเดือนก่อน

    Bless you! Please continue doing what you're doing! You're an angel

  • @sagaranilkumar8619
    @sagaranilkumar8619 2 ปีที่แล้ว

    Oh thanku so much for that wonderful class helped me to understand the topic very much... plz keep going and post more videos..

  • @sadraaghanoor
    @sadraaghanoor 2 หลายเดือนก่อน

    I would like to thank you for your clear explanation. ❤

  • @celinaleal7692
    @celinaleal7692 8 หลายเดือนก่อน

    Love your videos! I'm doing biomed and some concepts I just cant' understand until you explain it. Also, omg I love Cells at Work too!!

  • @milliecroft1200
    @milliecroft1200 9 หลายเดือนก่อน

    I dont think ive ever commented on a youtube video in my life, but this was so helpful i almost did a backflip out of joy, thanks !!!!!

  • @ethancraeynest4183
    @ethancraeynest4183 ปีที่แล้ว

    very clear and specific video, just hoped you would take about the types of interferones and the "component system" too. This would have helped to be even more complete. Maybe talking about the NK-cells too but overall very very good video

    • @martashenker
      @martashenker ปีที่แล้ว

      NK cells are part of the innate immune system, that's why they are not being discussed here

  • @dinabereket569
    @dinabereket569 หลายเดือนก่อน

    Thank you for what you do ! really helpful

  • @hamzaha.al-quaid2441
    @hamzaha.al-quaid2441 2 ปีที่แล้ว +1

    Really awesome big picture video. Thank you🙏🧬

  • @pulkitverma8104
    @pulkitverma8104 ปีที่แล้ว

    Brother one of the finest video on this topic.....you got my respect 👍🏻🤝🏻

  • @khalidabdulfattahmutwally9286
    @khalidabdulfattahmutwally9286 ปีที่แล้ว

    Extremely beautiful and beneficial. I love that so much.. please continue

  • @v.2435
    @v.2435 ปีที่แล้ว

    This is so concise, Thank a lot Prof. !!!

  • @ajaklual1689
    @ajaklual1689 3 หลายเดือนก่อน

    You are a great teacher 😊😊😊

  • @evamaryanti800
    @evamaryanti800 11 หลายเดือนก่อน

    Not so convincing coughing, but the lecture was amazinggggg. Thanks!

    • @SiebertScience
      @SiebertScience  11 หลายเดือนก่อน

      So you’re saying I shouldn’t quit TH-cam to become an actor??? ;)

    • @johnaghogho2435
      @johnaghogho2435 2 หลายเดือนก่อน

      Lol no ...we still need you ​@@SiebertScience

  • @jenniferthomas6592
    @jenniferthomas6592 ปีที่แล้ว

    This was super helpful! Thank you!

  • @sandyable
    @sandyable 2 ปีที่แล้ว

    so far your videos have been very helpful:) thank you for making it easier for us. although I didn't believe you were sick :x

  • @ilaly8347
    @ilaly8347 7 หลายเดือนก่อน

    You’re literally the best!!! I don’t know why you don’t do biochemistry😭

    • @SiebertScience
      @SiebertScience  7 หลายเดือนก่อน

      I’d love to do biochemistry someday. But this isn’t my job…I do all this stuff in my spare time, so I’m pretty limited in how much content I can make.

  • @kimmagri181
    @kimmagri181 2 ปีที่แล้ว +1

    Very helpful ! Thank you so much :)

  • @cortneyellyn3233
    @cortneyellyn3233 7 หลายเดือนก่อน

    When you're taking a 6 week online accelerated A&P 2 class before nursing school starts-- you're freaking out and then you find Siebert Science. I may pass now. THANK YOU. lol

  • @aggelikinakou_
    @aggelikinakou_ 2 ปีที่แล้ว +1

    oh my god, thank you so much for this video, immunology is driving me crazy

  • @AlaaSalah-jc1gl
    @AlaaSalah-jc1gl 20 วันที่ผ่านมา

    U are amazing, man ❤

  • @yhwhspirit
    @yhwhspirit 7 หลายเดือนก่อน

    I thank God for helping me find this channel 🙏🙏 immunology best explanation ❤

  • @AlaaSalah-jc1gl
    @AlaaSalah-jc1gl 20 วันที่ผ่านมา

    I really have fun with you 😂 I've repeated the part of " wanting for you " many times😂❤

  • @taylorguarino1555
    @taylorguarino1555 ปีที่แล้ว

    Thank you so much for this amazing video

  • @rajabumlaluko2897
    @rajabumlaluko2897 ปีที่แล้ว

    I found it more helpful and easy to understand

  • @lamarjr001
    @lamarjr001 ปีที่แล้ว

    You’re the best!!🏆🔥

  • @mohammedshamboul3145
    @mohammedshamboul3145 ปีที่แล้ว

    Thank you
    You are good medical teacher I watch in youtube

  • @Ahmad_Fawaz
    @Ahmad_Fawaz 2 ปีที่แล้ว +1

    Can you make vd about the non-specific?

  • @bouthainagarna7680
    @bouthainagarna7680 5 หลายเดือนก่อน

    Thank you so much that was very helpful

  • @LanaNY0114
    @LanaNY0114 6 หลายเดือนก่อน

    THANK YOU SO MUCH 🙌🏼🙌🏼🙌🏼🙌🏼🙌🏼

  • @Heh18287
    @Heh18287 7 หลายเดือนก่อน

    thanks you for this AMAZING explanation, and you should definitely be an actor😂

  • @BirhanuChalie-d7n
    @BirhanuChalie-d7n 8 หลายเดือนก่อน

    Fantastic lecture and comments

  • @suzankhaled3641
    @suzankhaled3641 4 หลายเดือนก่อน

    That is amazing specially the fake cough 😂❤

  • @prernapatil6458
    @prernapatil6458 ปีที่แล้ว +1

    can you just clear a doubt ? How can cells retain specific memory of any pathogen in spite of having average life span?

    • @karl_fischer
      @karl_fischer ปีที่แล้ว +1

      they keep dividing into new cells and passing on the information.

  • @TP-mv6en
    @TP-mv6en 2 ปีที่แล้ว

    This is a great video thanks so much for making it

  • @samanthaagneslumapas8479
    @samanthaagneslumapas8479 ปีที่แล้ว

    Big help 🎉 thank you!

  • @grrrrr219
    @grrrrr219 2 ปีที่แล้ว

    hataraku saibou in the background! It's a good show focusing on body immunology ! 😄

    • @SiebertScience
      @SiebertScience  2 ปีที่แล้ว +1

      I was hoping some people would notice that! Great show!

  • @jonnymercy4528
    @jonnymercy4528 9 หลายเดือนก่อน

    best guide ever!

  • @eman.hasann3335
    @eman.hasann3335 ปีที่แล้ว

    U r one of the best youtuberrrr❤❤❤❤❤❤❤

  • @anabutler5675
    @anabutler5675 5 หลายเดือนก่อน

    YOU ARE THE BEST!!!!

  • @sookieseestruth7573
    @sookieseestruth7573 11 หลายเดือนก่อน

    This was the bomb. Thank you

  • @32stillgrowingup
    @32stillgrowingup 3 หลายเดือนก่อน

    THANK YOU THANK YOU THANK YOU!!

  • @mangajunction8762
    @mangajunction8762 2 ปีที่แล้ว +2

    This is good ✨

  • @vectorie6195
    @vectorie6195 2 ปีที่แล้ว +1

    Thank you so much

  • @lol-i2d9e
    @lol-i2d9e ปีที่แล้ว

    thanks heaps for this video!

  • @JarodKientz
    @JarodKientz 3 ปีที่แล้ว +3

    I like the Cells at Work easter egg.

    • @SiebertScience
      @SiebertScience  3 ปีที่แล้ว +1

      Yeah, I just discovered the show last week! So good!

  • @파이브-t6w
    @파이브-t6w 4 หลายเดือนก่อน

    I wish you were my biology teacher

  • @chibuikeolachukwu1800
    @chibuikeolachukwu1800 หลายเดือนก่อน

    Am i the only one. That thinks this man is ADORABLE 🥰🥰🥰🥰🥰🥰

  • @trinityg8511
    @trinityg8511 ปีที่แล้ว

    the best video to explain this. I really wanted a clear cut, step by step demonstration and this is incredibly helpful. thankyou!

  • @medianayaseen1610
    @medianayaseen1610 ปีที่แล้ว

    I have a question regarding the B cell maturing in the bone marrow i read in multiple sources that it start’s developing in the bone marrow but continues in the spleen to final maturation but i also read it matures in the bone marrow so can you tell me which is true?