Q&A: The Latest in PD Research 2023

Q&A: The Latest in Parkinson's Research 2023 with Jeff Bronstein, MD, PhD, from UCLA.
A Parkinson's Community Los Angeles (PCLA) "Let's Talk Parkinson's" online live program from July 27, 2023. www.pcla.org.
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Timestamps:
00:00 Intro
01:42 Dr. Bronstein Intro
02:37 What Causes Parkinson’s?
06:12 α-Synuclein Pathology
07:44 Vagotomy Reduces Risk of PD
08:35 Where PD Starts
10:04 Symptoms
11:54 PD Process Spans Decades
12:46 What Starts the PD Process?
17:10 Environmental Factors
20:47 Disease Pathways
22:16 Promising Diagnostic Tools
25:08 Promising Therapies
28:46 Prothena
30:18 GLP-1 Agonists
31:36 Exenatide and PD
32:01 1st Disease Modifying Therapy
33:38 Promising Symptomatic Therapies
36:02 Continuous Levodopa Delivery
36:38 New UCLA Faculty Research
38:38 Q&A
56:29 Closing
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[@rosielux108]

Excellent presentation. Really appreciated the detail. I’m a yoga teacher who specialises in PD. The more people can understand PD the better, and it helps people feel like they have some control and choice in the treatments and protocols they employ.
Thank you 🙏🏽

[@carbonejack]

Extremely helpful presentation, in a way I can understand the dynamics of PD. I'm currently in the Fox Foundation PPMI research study. This video helps me understand what I have experienced over the years; constipation, loss of smell, RBD. Fast forward to today. I'm now experiencing rigidness and walking issues. I've not been officially diagnosed, but I believe it's just a matter of the time in the next step of my participation in PPMMI.

[@Bestvidoes3078]

Homeopathic medicine plumbum met 200

[@monika6974]

Extremely helpful presentation, in a way I can understand the dynamics of PD.

[@laggerb4680]

I wonder how I’m diagnosed with pd (tremors & tension in arm muscles, abnormal Datscan) yet not ever had constipation, reduction of smell, or continual sleep problems). I’m female 78 yrs old.

[@PaulHigginbothamSr]

So this seems to be related to prion disease like mad cow disease. With cow prions you almost have to burn the bodies to remove the prions. What we need to develope is a good protein that takes the irregular shaped proteins and turns out correctly shaped proteins. Possibly a virus like infection that eats the misfolded protein and turns out good proteins. Hopefully we find something that removes the bad protein and does not make us permanenetly ill. 57:47

[@user-re9wf1ts4x]

What is the medication to use for parkinson dísease

[@FatherSebastiaan]

what about Vaxxinity's new UB312?

[@user-jb6no9ty3t]

My husband had pd he always had a healthy diet ate alot of fish and fruit never drank alcohol or smoked so what the answer to that he died at age75 lost his swallow horrible death listener in Ireland

[@normanrubenzer]

im shocked that the red light therapy is all hype!!! there are companys like symbx in australia having suscess and in canada.. so my wife is thinking about the duopa pump but would prefer the small pump verses the big one.please let us know when the fda approves the new pumps

[@peter572]

Can photo-bio-modulation therapy halt or improve PD symptoms?

[@deborahd.7281]

They keep developing more and more expensive drugs that they can patent that may not be any better than previously developed drugs. Photobiomodulation is used in New Zealand, Australia, and Europe. There are several devices ranging from a few hundred dollars and higher that have shown significant benefits. It seems that most neurologists in the United States will say, "oh, not enough research on that".
These drugs have major negative side effects, photobiomodulation generally has beneficial side effects.

[@gailcline9023]

27:39 27:41

[@lillianateran3666]

por favor traducir en español

[@roscoro]

Utiliza el botón de configuración y te dará traducir como una opción y lo pones en español

[@rexeverything6249]

Abel kinnaese inhibitors are whats needed inhibikase ikt-148009 is the one second phase trials now

[@kevinfitzgerald7474]

What's the research. You found the cause. It's not genetic.

[@ivarsmednis]

I 2:03 ii😅jiiii

[@carmengloriadelgado9102]

Hola, estoy muy interesada en saber si podían dar traducción en español de lo expuesto?, muchas gracias, un saludo

[@ParkinsonsCommunityLosAngeles]

Hola, deberías poder utilizar las herramientas de TH-cam para traducir esta charla al español. Gracias por ver

[@erinoreilly4496]

Since PD has a strong gut connection, I wonder if not being breastfed is a risk factor for PD?

[@stephendunn2733]

For a different reason I have wondered the same. The number with PD in Australia has doubled since 2015. Median age of diagnosis of 61 aligns with the huge switch in Australia to formula feeding during the fifties as it was viewed as being more socially acceptable.

[@danielprose5878]

Removing alpha synuclein from this area was not affective and showed no relief or stopped the condition. Sadly !

[@rexeverything6249]

Inhibikase therapeuticshas it worked out with there drug ikd-148009