Diabetes insipidus (DI) Internal medicine
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- เผยแพร่เมื่อ 15 มี.ค. 2018
- 📌 𝐅𝐨𝐥𝐥𝐨𝐰 𝐨𝐧 𝐈𝐧𝐬𝐭𝐚𝐠𝐫𝐚𝐦:- / drgbhanuprakash
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Diabetes insipidus (DI) Internal medicine
Diabetes insipidus (DI) is a condition related to water balance and fluid regulation in the body. It is not to be confused with diabetes mellitus (the more common form of diabetes), which is related to blood sugar regulation. Diabetes insipidus is a disorder of the posterior pituitary gland or the hypothalamus, both of which play a crucial role in maintaining the body's water balance.
There are two main types of diabetes insipidus: central diabetes insipidus and nephrogenic diabetes insipidus.
Central Diabetes Insipidus (Neurogenic DI):
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This type is caused by a deficiency of the hormone vasopressin (also known as antidiuretic hormone or ADH) produced by the hypothalamus or released from the posterior pituitary gland. Vasopressin helps regulate the body's water balance by controlling the reabsorption of water in the kidneys.
A problem in the production, release, or function of vasopressin leads to excessive urination and an inability to concentrate urine, resulting in the excretion of large amounts of diluted urine.
Central DI can be caused by various factors, including head injuries, tumors, infections, autoimmune diseases affecting the hypothalamus or pituitary, and sometimes it can be idiopathic (unknown cause).
Nephrogenic Diabetes Insipidus:
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This type is characterized by the kidneys' inability to respond to normal levels of vasopressin, even when the hormone is present in adequate amounts.
The kidney tubules do not properly reabsorb water, leading to the excretion of large volumes of dilute urine.
Nephrogenic DI can be caused by genetic factors, certain medications (e.g., lithium), kidney diseases, and electrolyte imbalances.
Diagnosis and management of diabetes insipidus are typically handled by internal medicine specialists or endocrinologists. The diagnosis involves a series of tests to measure urine output, concentration, and blood levels of vasopressin and other related hormones. Imaging studies like MRI may be used to identify structural issues in the brain or pituitary gland.
The treatment of diabetes insipidus depends on the type and underlying cause. For central DI, synthetic vasopressin or desmopressin (a synthetic ADH analogue) can be prescribed to replace the deficient hormone. In nephrogenic DI, treatment focuses on addressing the underlying cause and managing symptoms, often with dietary adjustments and certain medications to enhance kidney responsiveness to vasopressin.
Diabetes insipidus (DI) is a disorder in which polyuria due to decreased collecting tubule water reabsorption is induced by either decreased secretion of antidiuretic hormone (ADH) (central DI) or resistance to its renal effects (nephrogenic DI). In most patients, the degree of polyuria is primarily determined by the degree of ADH deficiency or resistance . Thus, the urine output may range from 2 L/day with mild partial DI to over 10 to 15 L/day in patients with severe disease.
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Since technology has taken over every aspect of our lives, sadly the art of teaching is nearly nonexistent. You sir are an amazing teacher. Thank you for posting this lecture!
Wow, thank you
But sadly there is no cure...
Such a delight to watch such a good lecture really a masterpiece by dr Rajesh gubba sir
Great explanation...this is called teaching...even I am not related to medical or medicine field but got complete knowledge...👌👌
Nice To See You. It is pleasure For Me To Comment Here!. Very Honest And Good!
Thank you very much for such a clear and concise presentation .
Miss u sir....and feeling happy to see ur lectures😊😀👌
its really helpful..thanks a lot sir .this makes this topic easy to understand for me. and also it coveres every information related to topic . again thankyou well explained!!!!
Respected dr Rajesh , sir I was doing endocrinology and was feeling bored reading slides of my ppt , came to TH-cam for some visuals and I just love this video . Each and every concept is clear and perfect . Please upload full video of endocrine disorders . Thank you so much !
It's my pleasure
Nice To See You. It is pleasure For Me To Comment Here!. Very Honest And Good!
Waa sir mashallah your way of delivering lecture is so clear stay blessed
Great lecture sir...thank u...
Very helpful sir thankyou 🙂
Thank you sir for this good explanation🙏🙏🙏
Thank you sir for detailed explanation of ADH
Very nice explanation sir..thankyou😊
great.. thank you
Thank uh sir for such type of useful video ..nd ur way of teaching is too good
Very nice lecturr sir..... Thanks for detail knowedledge about DI....
Thank you Dr. Very helpful explanation 👍
Tnq so much sir... U teach very well
Very excellent explanation sir thank you so much
Tq sir your teaching is really awesome...
Lot of respect which don't make study a business
Absolutely loved the way you teach and cover all the points ❤👏
Thanks a lot 😊
i am appreciate your excellence explanation
Superb sy b upper 👍
very helpfull sir ty
Thankyou soo much sir.....
thanks a lot
Very nicely explained
Thanks sir......👌👌👌
Thank you sir.
This is one of the most precise explanation of diabetes insipidus disorder, thanks alot sir,keep move on and make further videos to serve the people most with your knowledge...!!
Amazing lecture excellent iam suffering with diabetic insipid
Where can i get more videos about another subjects for this doctor?
Really helpful
sir really very helpful and your explanation is tremendous plzzzzssir i insist one video upload on diabetes mellitus
Great teacher 👌👌
thank you sir
Very clear explanation. Understandable also to a non-medical person. Excellent!
Thank you kindly!
Great sir
Thank you Doctor. Wonderful lecture! God Bless.!
You are very welcome
Thank.you.very.much.sir.
Thnq for the video sir. It really helped me
Glad to hear that
Thx sir given knowledge about this 😊
Most welcome
Sir Please upload video on knee joint and hip joint
Wonder ful sir
Awsome video I have been using 40 iu vials (using 6mm BD syringes) for insulin for the last one month but I want to shift to insulin pen since it has 4mm needle size ,but the pen has cartridges of 100iu , how to convert the 40 iu doses to 100 iu ? For instance I take 35 units of insulin from the 40 iu vial how much should I take from the 100iu ,that would be equivalent thanks
Do more videos sir. I'm ur student From mist Hyderabad.
Very well explained sir .... thank you😃
Thank you sir your video is very help ful for me
very good presentation. thanks for explaining it in such easy way 😊
May I ask what kind of medicine you had that solve this issue?
hi sir, just read that despite of pressure effect and resultant damange to posterior pitutary, hypothalamus still can secrete ADH direct to circulation.. whats your take on this
well understood
Very good lecture
Perfectly taught. I understood this lesson very well and was able to do my practice Mcqs. Thank you😌👏👏👏
i know it is kind of off topic but do anyone know a good place to stream new series online?
@Kyng Kyng try Flixzone. You can find it on google :)
@Grayson Ibrahim yup, have been using FlixZone for months myself :)
@Grayson Ibrahim Yup, I've been watching on flixzone for months myself :D
@Grayson Ibrahim thank you, signed up and it seems like they got a lot of movies there =) I appreciate it !!
Sir I want to know about diabetes started from which point OR bomber pls sir possible answer me, next 6.8 are any diabetes chance OR fear pls answer me, sir if you answer this things that is very big help me also, Thanks. pls take care. have a nice day.
Thank you🎉
You’re welcome 😊
Thank you so much sir
Most welcome
where i can met u
rajesh is the best teacher i ever know he is currently teaching us in DR. BHATIYA CLASSES
Kaushal Lata thank u for all the love
nyc sir......👍👌
👍🏻 awesome sir....thankyou
Most welcome
Nice explanation more helpful if treatment dose aslo included
What is trauma
Sir
dr.what is the treatement available for Central dibeties inspidus for cured.
Osm yaar
Nice 👍
nice
Beautiful Explaination 💓
Glad you liked it
@@doctorbhanuprakash its our pleasure to watch ur highly knowledgeable view
Good sir
Sir, isn't Thiazide Diuretic has the exact opposite effect? Isn't it actually used to clear water from the body? Here, we want to re-absorb the water to prevent excess water loss in the form of urine.
Sir how to fully control this Disease
Good mornig sir pls about diabetes melitus
Awesome explanation 👏 👌
Glad you liked it
Easy to understand 🤩👌
Tysm
I want to detail about hypothyroidism
How to measure urine osmolality?whats the formula?@Dr.G.bhanu parkash
Really good
Thanks!
Sir how sickle cell anemia can be the cause for nephrotic diabetic incipidus
Please explain 🙏
Sir please upload cvs lecture
dr please can u explain by hindi plz I am from nepal m suffered from this problem.
👌👌👌👍
👍🏻👌🏻
👍🙏🙏
This has been a challenging time, I appreciate you so much Dr igho, because you restored back my health, with your Herbal, i got from your TH-cam channel, thank you so much for curing my Disease naturally, You are a Godsent
sir good day my brother suffering now diabetes insipidus please help me get a medicine for him. please thank you
You are father ok yes or no
I have diabetes insipidus? i was admitted CCU NRS medical college season on August 23 2020,
Ab kaisa hai
Sir
ADH hormone ki synthesis body m kha pa hoti h
Hypothalamus ke supra optic nuclei Ke magnocellular neurons me, 9 amino acid hote hai isme
Ok
I am suffering from Diabetes Insipidus .I took desmopressin medicine for a year but it didn't work.
How are u now? Even I suffer from this disease
Take chlorpropamide or carbamazepine
With desmopressin
@@hamzajarrral9044 which medicine you are taking ? is their any betterment for di?
বাংলায় অনুবাদ চাই।Please translate to bengoly.
How hypernatremia occurs in patiens with diabetes insipidus?
pooja aryal
There is free water excretion in Diabetes insipidus so there is hypernatremia
very slow rate of teaching
kindly improve it
which doctor cure this I have this diseas pls help me
Endocrinologist
There is no cure for this one . I have been suffering from the last 16 years.
@@poojajaidka1784 Really?
@@poojajaidka1784 im suffering from 8 years
@@SomNath-cm3jn yes
.
Nice To See You. It is pleasure For Me To Comment Here!. Very Honest And Good!
Tq sir your teaching is really awesome...
Thank you sir
Nice To See You. It is pleasure For Me To Comment Here!. Very Honest And Good!
Nice To See You. It is pleasure For Me To Comment Here!. Very Honest And Good!
Nice To See You. It is pleasure For Me To Comment Here!. Very Honest And Good!
Nice To See You. It is pleasure For Me To Comment Here!. Very Honest And Good!