Just to vent to my vegan community: I came across a video from a channel that I followed for personal growth and inspiration but they have branched into health topics. They had a video about being young fit and healthy forever. The "doctor" was quoted early on saying that you have to eat a ridiculous amount on a plant based diet and compared quinoa and chicken breast. I don't know if we are ever going to properly educate the majority of people because of these propagated misconceptions. When I'm talking about plant based diets My parents still throw in "there are some things missing" it's like the information can't get past previous biases.
Hi, there is an incredible bias against veganism in the omnivore world. It is true, studies show vegans in general are low or deficient in many nutrients which we need to pay attention to. I think this is the main reason for "failed vegans". However, the omnivore diet (and carnivore, keto, etcetera) are also low (or deficient in) several nutrients, but you never hear about this from critics of veganism. How about having your parents watch several of Dr. Greger's videos, and getting your parents to get a blood test and show them they are far from perfect!. I have been vegan 20+ years and humans are fearful of changing, especially away from animal flesh and blood. Here are some examples.....cheers pubmed.ncbi.nlm.nih.gov/26502280/ pubmed.ncbi.nlm.nih.gov/34069944/ nutritionfacts.org/video/omnivore-vs-vegan-nutrient-deficiencies-2/
I don't know why but I found you very endearing in this video. You would make such a good professor, the way you talk and make complicated subject matter much easier to understand and digest. And you make it interesting with humor and a lightness about you. Glad people like you exist in the world.
I love how you spend hours and hours reviewing all these studies and then you're nice enough to thank us for watching less than a 30 minute video. I have listened to a few of David Sinclair's videos. Great constructive criticism and review of his points.
So excited to see this vid, Mic. I had a friend buy me Sinclair's book, Lifespan. Such a wonderful read. Look forward to hearing what you have to say!!
Great video. Very thought-provoking especially about metformin. I would love to see a study on longevity on people who eat a WFPB diet comparing those who took metformin and those who didn't. I am waiting for those results before starting to take metformin myself as I am not diabetic.
I learned a lot as always! Thank you for all of your hard work over the years Mic. All of your nutritional science has really helped me shut down all of the annoying criticisms of my diet and lifestyle that meat heads throw at me, and I've even changed a few minds: all thanks to your information! Keep up the hard work my friend!
So glad to see that ur channel has grown quite a bit! I remember how, 3 years ago, it had way too little attention for how good the info already had been. Keep spreading the truth brother, cuz you’re changing the world for the better.
Thanks for doing this video Mic. Grateful for all your research. I agree, staying away from drugs for longer life and being on a meatless whole foods diet is the magic pill for a longer lifestyle. I started a healthy lifestyle at 20 with meatless diet and mountain biking for over 35 years/ being 65 now with a BMI of 21 and a BP of 110/65 and resting HR of 47. And living longer now than most of my my grandparents who died of strokes and heart disease. Except for one grandmother who lived to be 98 because she also lived a healthy low meat lifestyle. I can truly testify that the lifestyle you have researched is truly the path to take. I look forward to many more years because of it. And I encourage anyone who wants to stay healthy and off of debilitating drugs and heart surgery when you get older to follow the lifestyle Mic has given us completely. And as to NAD and Sirtuins are stimulated form Sulpherphane found in high levels from broccoli and kale. I put a lot in my smoothies every morning.
I wish I could like it everytime I watch it. Great job to condense those complex information in such a great video! I have watched all of Sinclairs talks and find his topic and findings fascinating. Will continue to follow his findings!
Thanks for your thoughtful, well researched videos, Mic. While I'm not yet totally plant-based, it's content like this that encourages me to keep plugging away.
An alternative to Metformin would be Berberine. It increased lifespan in mice and is available as a supplement. However, there are many things that might increase lifespan (such as exercise, healthy weight, nuts, Omega 3, garlic, tea, coffee, berries, Chlorella, ginger etc).
I am following David Sinclairs protocol I am 65, I have been watching you for a few years now,I went total vegan for one year I wanted it to work for me, but it killed my gut and I think gave me a slight case of IBS. now I fast 16 to 18 hours a day,calorie restrict and eat a more ketogenic diet,things are better for me, thats all I wanted to say,,and thanks for your videos I believe you help people..
Thanks for sharing. I think being a vegan have me candida it was scary - once I eat meat my digestion gets good again.. I wish I could eat plant based but the meat does the trick I guess..
@@ganapatikitty I promise you it's only because your body is so used to your current way of eating. Anyone can eat plant based👍🏻😁 it's all about how you transition.
The way you can research all of this is truly incredible!! Great video. Literally would never have come across some of the stuff you said if i wasnt subscribed to you. Thank you for that.
I'm 70 now. My father died at 44. One grandfather at 53. I take no medications and try to be a vegan, especially when I can fully control my diet. Your video's are great, as most of us do not understand all the science. But since I stopped working, exercise has decreased, as I used to bike or walk to work. So ... daily exercise...
Your explanations and research are 10X better than almost all doctors (incl those on youtube) who just repeat the findings of his research and aren’t practical in application at all. Thank you for doing what you do.
" *You cannot deny large scale studies like this one (**20:47**) showing that higher total antioxidant intake was associated with 38% lower all-cause mortality* " Watch me. The keyword there is "associated," a synonym of "correlated." Surely you're aware of the importance of distinguishing between correlation vs causation? Those with higher antioxidant intake almost certainly have healthier diets and lifestyles overall than those with lower antioxidant intake. So it's most likely these diet and lifestyle factors that affect the mortality, more than antioxidants. If you're going to claim that the antioxidant theory of aging is still valid, then you'll need to find studies that truly isolates antioxidants, correct for other diet and lifestyle factors, and that show an increase in longevity and lifespan. Bet you can't...
Great video Mic, and agreat quote too! "The best strategy for animals (for increased longevity) is not to eat animals". I'll be citing you so much this week. Best regards ^^
As I recall the summary of the study on the Okinawan diet shown in your chart did conclude that they were very active physically and at that time were in a 200 calorie a day deficit according to their calculations. I model my own diet after this evolutionarily proven diet which jives with all the science we now have so I am familiar with the chart intimately, and my own personal observation has been that on some days when I drop to 1500 calories from their 1750 average I feel even better than if I grab the nuts and add extra 200 calories or more. And yet my body weight remains fairly consistent. The Okinawan diet is VERY efficient. Also, inexpensive at about $6 a day for me. Another critical factor in that same data brings up the notion that not all calories are created equal where the human body is concerned. The "O" chart indicates an incredibly low fat intake of 6 percent and 9 percent protein with about 85 percent carbs. Without the fat to gum up the works the mitochondria and other cell functions are extremely efficient. In addition, the Okinawans embraced the idea of eating til 8/10ths full which is suggestive of calorie restriction as a lifestyle. Add to this that they drank green tea all day which I find to give a pleasant anorexia. As far as eating disorders these longest living people enjoyed being hungry at times of the day as I have found by eating the way they did. This is not an eating disorder but simply observing a sensation that monk's have known for millennia which is that to really enjoy something you must experience some emptiness and enjoy that as well. Everything I have learned about the Okinawans leads me to believe they were physically active a good bit of the day although not running track or at the gym, they ate sparingly a diet of mostly sweet potatoes, rice and vegetables, they drank green tea and they lived on an island that was somewhat isolated and probably were exposed to very few damaging viral diseases that would have infected the cities in the mainland areas. Certainly the idea of drugs would have been unthinkable to these people as it should be to us all. We live in a medical matrix and few see true reality where health is concerned. Like chumps taking street drugs we are fooled too often by profiteering drug pushers and peddlers of misinformation.
Thank you for always making this information digestible!!!! And for linking all studies that you reference!!! You put soooo much hard work into these videos and I hope you know how appreciative I am!!! 🌳🌿🌱
I have diabetes type 2 and I decided not take insulin or pills for treatment like a 2 months ago I started this vegan diet got my diabetes decreased from 300 to 143 and it’s still working out and I am 54 in old and feel wonderful
That was an amazingly informative vid on anti-aging! Thanks!! Sometimes its far simpler than most think, eat WFPB and keep a good weight as well as sleep. Mental and emotional health is a big one too. All those supplements may not be assimilated to the body and it could end up being damaging more than good? I used to take well over 50 supplements a day while really serious about training weights but now with more studies I realize too much is not better.and presently take far less, the minimum, and feel great!
Pretty much everything you can find in supplements, you will find in real foods. But with real foods you get the complete package, meaning better absorption and utilization. Also much cheaper.
😊😊😊 This video made me smile even more that the others. Thanks. Lots of witty amusing touches sprinkled right through, and of course your own smiles seen often too. 👍. Clearly a huge amount of research. Plenty for the viewer to digest. Or to try. Somehow I too would rather concentrate on and improve/correct if possible things like diet, exercise, sleep rather than chugging down supplements. Though I'm 62 to your 30. Yes exercise is my weak spot too... must do something about it. Anyhow, thanks again for an informative and very enjoyable video though it did keep my mind on its toes to keep up with all the knowledge.
@@OneFunPierre the benefit listed is relative, not absolute, and the longterm side effects are not good. It's just a well-marketed product sold to doctors who don't know any better. Watch Dustin Rudolph and John McDougall on this.
It's insane how many doctors are taking metformin for anti-aging. Ok, well, maybe not that insane -for them- since they are so obsessed with pharmaceuticals and not that into total body health. SMH. I've heard diabetes patients go on and on about side effects. So not worth it, we don't know enough. They just did a recall on a few metformin generics for cancer risk.
Well I have watched so many Sinclair interviews over the past year, even ordered his book and am still reading it. I've also heard Dr Rhonda Patrick talk about the same topics. Nothing against them two, but your summary of all of these topics is so much clearer. Now it may help that you don't have Joe Rogan interrupting and trying to steer the convo, but still, this is such a clean presentation.
Some of the anti aging supplements and strategies are conflicting though. Loss of muscle mass is a huge part of health decline in old age yet suppressing mTor leads to less protein uptake and to muscle loss. Also Metformin and Resveratrol have been shown to lessen the good effects of exercise. I have taken the course of exercise as anti ager with weights and high intensity. I do take MNM though as that one seems to boost energy and weirdly make my nails strong again (!). Longo recommends plant based up until age 70 when you need to add in some animal protein due to easy absorption and the increased need for protein. He suggests eggs and cheese and fish.
Just an anecdote: I did a fasting-mimicking diet (FMD) for 5 days a while ago. I lost a bit of weight, but didn't lose any muscle. In fact, my first aerobic exercise after the FMD, was great. I took a vitamin supplement, of course. I will definitely keep trying it, since, although it was hard, the autophagy and loss of fat but increase in lean muscle mass, does feel good. I did do yoga and meditation and ate healthy, in-between. Love your vids and humor, Mic. Good work! I'll set some green tea and coffee now
Dear Mic, I just found your channel and I'm already deep in love with it. I would like to understand more about the sirtuins signalling pathway: activation, regulation, downstream effects. I was looking into it as linked with calorie restriction, but I just found a lot of reference to NAD and resveratrol. Could you address me to some material explaining this pathway and its correlation to CR? Thank you so much in advance, Roberto.
Eating nutritional yeast, fortified or unfortified, raises our IGF1 level. Jeff Novick and Alan Goldhamer mentioned it in a comment. Do you have any scientific papers on that?
@@welcomeback2mychannel I am sure it is OK to eat it once in a while but I see so many recipes using 1/2 cup to 1 cup and people sprinkling it on top of whole grains, tofu, vegetables... Even Dr Fuhrman is not hot about it. I was just wondering if there were some solid studies about it. I'll post the link from Jeff Novick but I understand people's suspicions clicking on links. Go to the John McDougall forum " of January 19 2013 to see Jeff Novick's answer. www.drmcdougall.com/forums/viewtopic.php?f=22&t=34262
I had heard a lot about these different pathways cause I'd seen many interviews with doctor Longo. But I forgot what most of the acronyms stand for, so thanks for refreshing my mind.
Still in my thirties, and just hoping I get to test these someday.... Animal ag is destroying the planet so fast that I fear ecosystem collapse will actually be what determines our "longevity".... Vegans need to be deeply concerned with the environment (everyone does) but more so *environmentalists absolutely need to adopt veganism!* Enjoyable video buddy, keep it up!
It's kind of a myth that animal agriculture is bad though, people always say they take a lot of water, but a lot of the water they take is actually just peed out onto the ground. It's not like if they drink 100 gallons of water they just keep it the whole time. They only keep what they need to maintain body weight. Same with the whole methane argument, it's really not as bad as people say. The real pollution problem comes from China and India these days. Especially huge plastic issues. I would say though, pasture raised farming is preferred. I would love to get rid of any corporitization of the food system. It would help farmers be free and not in debt. Also just keeping animals in feeding lots is horrible. You have to understand though these studies on meat are limited, we don't actually know if eating meat is as bad as a lot of vegans say. Eating bad processed meat sure, but a lot of studies on meat are following people who also smoke and make a bunch of other bad lifestyle decisions. People who are vegan are usually more health conscious and don't smoke etc.
@@Hoppensagen you should look at the studies on land use.... they explain we could rewild an area the size of Russia back into natural biodiverse habitat, which would really help with both carbon absorption and stabilizing the climate. It would also help slow the mass extinctions already underway. But really, it's the whole impact of all these things put together, not just one variable. Land is by far the big one when it comes to animal agg though. People still act like we have no limits to our consumption and I still see people throw trash out the window and find it pretty much everywhere. We are just too stupid to realize we're killing our beautiful planet through our everyday decisions, and food is the biggest factor in that. We get terrified over a bad cold spreading around, but can't see the very obvious things we've done that are making the ecosystem break down. And somehow we think we'll just move to Mars if it gets real bad, which is even more absurd. I'm not sure we deserve this paradise and soon it'll be too late to do anything about the damage we've done
I really enjoyed this video, I am grateful for the energy you put forward to create it. I learned a lot and also achieved a better understanding of information that I was familiar with. Thank you, Mic.
Great Vid as always Mic, I will definitely need to watch this one again as there is much to take in. Interesting about the height/ longevity connection.
Just to vent to my vegan community: I came across a video from a channel that I followed for personal growth and inspiration but they have branched into health topics. They had a video about being young fit and healthy forever. The "doctor" was quoted early on saying that you have to eat a ridiculous amount on a plant based diet and compared quinoa and chicken breast. I don't know if we are ever going to properly educate the majority of people because of these propagated misconceptions. When I'm talking about plant based diets My parents still throw in "there are some things missing" it's like the information can't get past previous biases.
Hi, there is an incredible bias against veganism in the omnivore world. It is true, studies show vegans in general are
low or deficient in many nutrients which we need to pay attention to. I think this is the main reason for "failed
vegans". However, the omnivore diet (and carnivore, keto, etcetera) are also low (or deficient in) several nutrients, but you
never hear about this from critics of veganism. How about having your parents watch several of Dr. Greger's videos, and getting your parents to get a blood test and show them they are far from perfect!. I have been vegan 20+ years and humans are fearful of changing, especially away from animal flesh and blood. Here are some examples.....cheers
pubmed.ncbi.nlm.nih.gov/26502280/
pubmed.ncbi.nlm.nih.gov/34069944/
nutritionfacts.org/video/omnivore-vs-vegan-nutrient-deficiencies-2/
I don't know why but I found you very endearing in this video. You would make such a good professor, the way you talk and make complicated subject matter much easier to understand and digest. And you make it interesting with humor and a lightness about you. Glad people like you exist in the world.
I found also that waking up in the AM super activates my Pikachu
HAHAHA
Peace By Vegan ⚡️
Best comment
If you know what I mean ;)
I don't particularly want to live forever.
But as long as I'm healthy, I won't want to die. So that kind of follows.
Ugh. This was fantastically full of information and legitimate studies as usual 🤤👏🔥 Thanks for making my brain happy :')
I love how you spend hours and hours reviewing all these studies and then you're nice enough to thank us for watching less than a 30 minute video. I have listened to a few of David Sinclair's videos. Great constructive criticism and review of his points.
Mike's outstanding in breaking down broad matters involving overwhelming research to it's key points that everyone can understand and digest
Read the book. Anxiously awaiting “How not to age” from Dr Greger
I’m so excited for that book, I can’t wait!
How not to age from someone that looks like a crypt keeper, no thanks
Even knowing that it does not exist, I would pre-order it right now if I could.
wcraca5 Sounds like your own judgements and mental health may be your first health issue to start with.
I already read How not to Die and got How not to Diet, will get around to reading it before autumn 🍂🍁🍂
So excited to see this vid, Mic. I had a friend buy me Sinclair's book, Lifespan. Such a wonderful read. Look forward to hearing what you have to say!!
I’m also a fan of the book and would love to know more on what Mic thinks.
Great video. Very thought-provoking especially about metformin. I would love to see a study on longevity on people who eat a WFPB diet comparing those who took metformin and those who didn't. I am waiting for those results before starting to take metformin myself as I am not diabetic.
I learned a lot as always! Thank you for all of your hard work over the years Mic. All of your nutritional science has really helped me shut down all of the annoying criticisms of my diet and lifestyle that meat heads throw at me, and I've even changed a few minds: all thanks to your information! Keep up the hard work my friend!
So glad to see that ur channel has grown quite a bit! I remember how, 3 years ago, it had way too little attention for how good the info already had been. Keep spreading the truth brother, cuz you’re changing the world for the better.
30 studies! Really appreciate all the research that goes into these videos. Thanks, Mic. 🙏🙏
Big thanks, Mic. 💗 You are so good at breaking down complex studies. 👍👍
Thanks for doing this video Mic. Grateful for all your research. I agree, staying away from drugs for longer life and being on a meatless whole foods diet is the magic pill for a longer lifestyle. I started a healthy lifestyle at 20 with meatless diet and mountain biking for over 35 years/ being 65 now with a BMI of 21 and a BP of 110/65 and resting HR of 47. And living longer now than most of my my grandparents who died of strokes and heart disease. Except for one grandmother who lived to be 98 because she also lived a healthy low meat lifestyle. I can truly testify that the lifestyle you have researched is truly the path to take. I look forward to many more years because of it. And I encourage anyone who wants to stay healthy and off of debilitating drugs and heart surgery when you get older to follow the lifestyle Mic has given us completely. And as to NAD and Sirtuins are stimulated form Sulpherphane found in high levels from broccoli and kale. I put a lot in my smoothies every morning.
WOW. This was a wicked amount of research, absolutely awesome video!!!!!!!!!!!!!!!!!
I wish I could like it everytime I watch it. Great job to condense those complex information in such a great video! I have watched all of Sinclairs talks and find his topic and findings fascinating. Will continue to follow his findings!
Thank you pikachu in the morning for keeping my mitochondria burning clean
That's a pile of research, Mic. Thank you for doing it so we don't have to (also, I didn't know that I didn't know half of this).
Thanks for your thoughtful, well researched videos, Mic. While I'm not yet totally plant-based, it's content like this that encourages me to keep plugging away.
I can find so many videos on both sides of these issues.
But I trust Mic the Vegan and Dr. Gregor.
Thank you for this.
It's amazing all the work you do behind the scenes for your videos. Thanks for all you do
An alternative to Metformin would be Berberine. It increased lifespan in mice and is available as a supplement. However, there are many things that might increase lifespan (such as exercise, healthy weight, nuts, Omega 3, garlic, tea, coffee, berries, Chlorella, ginger etc).
Great job condensing the research into understandable concepts.
I am following David Sinclairs protocol I am 65, I have been watching you for a few years now,I went total vegan for one year I wanted it to work for me, but it killed my gut and I think gave me a slight case of IBS. now I fast 16 to 18 hours a day,calorie restrict and eat a more ketogenic diet,things are better for me, thats all I wanted to say,,and thanks for your videos I believe you help people..
Thanks for sharing. I think being a vegan have me candida it was scary - once I eat meat my digestion gets good again.. I wish I could eat plant based but the meat does the trick I guess..
@@ganapatikitty transition slowly. This will make you body be able to adjust properly.
@@ganapatikitty I promise you it's only because your body is so used to your current way of eating. Anyone can eat plant based👍🏻😁 it's all about how you transition.
dying to know how you keep track of all your citations!
Wow... Metformin also has been shown to increase dementia when taking long term. So longer life, but at what cost...
Exactly. I tried it and my feet started burning.
Yes, using this drug to promote life extension is not a good idea
Way too many reported side effects. Scary!
I actually have to take this med. PCOS= insulin resistance. Stopped taking it and BLEW UP! That was on a less caloric diet and more active, smh.
@@sweetcaramelsmile Glad it's working for you. Any side-effects in your case?
The way you can research all of this is truly incredible!! Great video. Literally would never have come across some of the stuff you said if i wasnt subscribed to you. Thank you for that.
I'm 70 now. My father died at 44. One grandfather at 53. I take no medications and try to be a vegan, especially when I can fully control my diet. Your video's are great, as most of us do not understand all the science. But since I stopped working, exercise has decreased, as I used to bike or walk to work. So ... daily exercise...
Your explanations and research are 10X better than almost all doctors (incl those on youtube) who just repeat the findings of his research and aren’t practical in application at all. Thank you for doing what you do.
Fantastic video, thank you for making these complex issues understandable! So important.
Oh my goodness you shoveled a lot in this video! Great job Mic!!
You are one of the few I trust. keep it up
Thanks @micthevegan appreciate the research! Great video, as always.
this was really informative and digestible, thanks for the info. not plant based myself but i really appreciate your perspective and knowledge!
" *You cannot deny large scale studies like this one (**20:47**) showing that higher total antioxidant intake was associated with 38% lower all-cause mortality* "
Watch me. The keyword there is "associated," a synonym of "correlated." Surely you're aware of the importance of distinguishing between correlation vs causation? Those with higher antioxidant intake almost certainly have healthier diets and lifestyles overall than those with lower antioxidant intake. So it's most likely these diet and lifestyle factors that affect the mortality, more than antioxidants. If you're going to claim that the antioxidant theory of aging is still valid, then you'll need to find studies that truly isolates antioxidants, correct for other diet and lifestyle factors, and that show an increase in longevity and lifespan. Bet you can't...
Great video Mic, and agreat quote too! "The best strategy for animals (for increased longevity) is not to eat animals". I'll be citing you so much this week. Best regards ^^
Good job to you man! Rich Roll shout out heck yeah!!
Yes! I was looking forward to this one! I’ll watch tonight. Thanks Mic!
Thanks for the link to the BROAD study
Amazing video I enjoyed your insights and the research love to join you on your next cruise
Great video! I just did the fasting mimicking diet for the first time and feel great
As I recall the summary of the study on the Okinawan diet shown in your chart did conclude that they were very active physically and at that time were in a 200 calorie a day deficit according to their calculations. I model my own diet after this evolutionarily proven diet which jives with all the science we now have so I am familiar with the chart intimately, and my own personal observation has been that on some days when I drop to 1500 calories from their 1750 average I feel even better than if I grab the nuts and add extra 200 calories or more. And yet my body weight remains fairly consistent. The Okinawan diet is VERY efficient. Also, inexpensive at about $6 a day for me. Another critical factor in that same data brings up the notion that not all calories are created equal where the human body is concerned. The "O" chart indicates an incredibly low fat intake of 6 percent and 9 percent protein with about 85 percent carbs. Without the fat to gum up the works the mitochondria and other cell functions are extremely efficient. In addition, the Okinawans embraced the idea of eating til 8/10ths full which is suggestive of calorie restriction as a lifestyle. Add to this that they drank green tea all day which I find to give a pleasant anorexia. As far as eating disorders these longest living people enjoyed being hungry at times of the day as I have found by eating the way they did. This is not an eating disorder but simply observing a sensation that monk's have known for millennia which is that to really enjoy something you must experience some emptiness and enjoy that as well. Everything I have learned about the Okinawans leads me to believe they were physically active a good bit of the day although not running track or at the gym, they ate sparingly a diet of mostly sweet potatoes, rice and vegetables, they drank green tea and they lived on an island that was somewhat isolated and probably were exposed to very few damaging viral diseases that would have infected the cities in the mainland areas. Certainly the idea of drugs would have been unthinkable to these people as it should be to us all. We live in a medical matrix and few see true reality where health is concerned. Like chumps taking street drugs we are fooled too often by profiteering drug pushers and peddlers of misinformation.
I am also restricting my feeding time and going to bed somewhat hungry. Amazingly, I am enjoying it! A lot! Thank you for your comment!
Talk about valter longo's longevity fasting-mimicking diet💚
nutritionfacts.org/video/the-5-2-diet-and-the-fasting-mimicking-diet-put-to-the-test/
Thank you for always making this information digestible!!!! And for linking all studies that you reference!!! You put soooo much hard work into these videos and I hope you know how appreciative I am!!! 🌳🌿🌱
Thanks for all the extra research info amd comedy.
I have diabetes type 2 and I decided not take insulin or pills for treatment like a 2 months ago I started this vegan diet got my diabetes decreased from 300 to 143 and it’s still working out and I am 54 in old and feel wonderful
Thanks for doing that - its a ton of research!
Wao Franklin this has been the most interesting video I had ever seen in a while I just wanna learn more about this increase on longevity stuff
Thank you for the rabbit hole research, this is why I love your videos!
Thank you Mic for another great video and this awesome summary about these acronyms like mtor etc. Great content, much love from Toronto 🌱
That was an amazingly informative vid on anti-aging! Thanks!! Sometimes its far simpler than most think, eat WFPB and keep a good weight as well as sleep. Mental and emotional health is a big one too. All those supplements may not be assimilated to the body and it could end up being damaging more than good? I used to take well over 50 supplements a day while really serious about training weights but now with more studies I realize too much is not better.and presently take far less, the minimum, and feel great!
Pretty much everything you can find in supplements, you will find in real foods. But with real foods you get the complete package, meaning better absorption and utilization. Also much cheaper.
Thank you for this great video! I appreciate the effort you put into the research and that you tell us the about the quality of the studies.
😊😊😊 This video made me smile even more that the others. Thanks. Lots of witty amusing touches sprinkled right through, and of course your own smiles seen often too. 👍. Clearly a huge amount of research. Plenty for the viewer to digest. Or to try. Somehow I too would rather concentrate on and improve/correct if possible things like diet, exercise, sleep rather than chugging down supplements. Though I'm 62 to your 30. Yes exercise is my weak spot too... must do something about it. Anyhow, thanks again for an informative and very enjoyable video though it did keep my mind on its toes to keep up with all the knowledge.
I'd be interested in your thoughts on Valter Longo's works with the fasting mimicking diet, unless you've covered it before..
nutritionfacts.org/video/the-5-2-diet-and-the-fasting-mimicking-diet-put-to-the-test/
@@michaelmore Thanks for the link. Can't go wrong with Dr Greger!
I love this! Great work on this video and wading through all the technical jargon. 😆
You are amazing 🙏🏼💜 thank you this was awesome 👏 all my questions answered 🧘♀️
15:42 I think you got that backwards, based on the Mariani quote.
I’m in my 50’s and an ex-pharma rep but I wouldn’t take Metformin.
Why?
@@OneFunPierre the benefit listed is relative, not absolute, and the longterm side effects are not good. It's just a well-marketed product sold to doctors who don't know any better. Watch Dustin Rudolph and John McDougall on this.
It's insane how many doctors are taking metformin for anti-aging. Ok, well, maybe not that insane -for them- since they are so obsessed with pharmaceuticals and not that into total body health. SMH. I've heard diabetes patients go on and on about side effects. So not worth it, we don't know enough. They just did a recall on a few metformin generics for cancer risk.
They gave me that for fertility. Didn’t work. Still childless.
@@msmreviews8408 me too
Thank you mike! You’ve done me so many favors. I love all your videos
Bravo, another masterpiece!! Love you
Love your work. Thank you so much.
We appreciate all the well researched and organized videos Mic, keep up the good work 💪🌱🙏
Comprehensive overview, Thanks!
Well I have watched so many Sinclair interviews over the past year, even ordered his book and am still reading it. I've also heard Dr Rhonda Patrick talk about the same topics. Nothing against them two, but your summary of all of these topics is so much clearer. Now it may help that you don't have Joe Rogan interrupting and trying to steer the convo, but still, this is such a clean presentation.
Some of the anti aging supplements and strategies are conflicting though. Loss of muscle mass is a huge part of health decline in old age yet suppressing mTor leads to less protein uptake and to muscle loss. Also Metformin and Resveratrol have been shown to lessen the good effects of exercise. I have taken the course of exercise as anti ager with weights and high intensity. I do take MNM though as that one seems to boost energy and weirdly make my nails strong again (!). Longo recommends plant based up until age 70 when you need to add in some animal protein due to easy absorption and the increased need for protein. He suggests eggs and cheese and fish.
Just an anecdote: I did a fasting-mimicking diet (FMD) for 5 days a while ago. I lost a bit of weight, but didn't lose any muscle. In fact, my first aerobic exercise after the FMD, was great. I took a vitamin supplement, of course. I will definitely keep trying it, since, although it was hard, the autophagy and loss of fat but increase in lean muscle mass, does feel good. I did do yoga and meditation and ate healthy, in-between.
Love your vids and humor, Mic.
Good work! I'll set some green tea and coffee now
Dear Mic, I just found your channel and I'm already deep in love with it.
I would like to understand more about the sirtuins signalling pathway: activation, regulation, downstream effects. I was looking into it as linked with calorie restriction, but I just found a lot of reference to NAD and resveratrol. Could you address me to some material explaining this pathway and its correlation to CR?
Thank you so much in advance,
Roberto.
Excellent points about the downsides of fasting, and great explanations of processes I vaguely understood before!
Thank you for taking your time to make this video! :) Very useful!
That you for doing all of that research!
🌱🌱🌱Hi Mic! Love your videos, thanks for great content! We’ll all make it to 100! 🌱🌱🌱
thank you for the effort you put into your videos!
I really enjoy the long video. Twas vert interesting and entertaining to boot. Big Ups!
Thank you for your informative video. I take niacin as it seems to me that NR and NMN are derivative of Niacin. Please correct me if I am wrong.
7:37
So I’ve got an ankle injury right now, and that standing up test proves I’m seconds from death
As I take an interest in longevity studies as well, I find this video amazingly useful!!! Thank you for your fantastic work!!! 😀
Good video 👍 I read that guy’s book a while back cool to see the summarization of further/different research in the field.
Eating nutritional yeast, fortified or unfortified, raises our IGF1 level. Jeff Novick and Alan Goldhamer mentioned it in a comment. Do you have any scientific papers on that?
never heard this before. i doubt it. sounds like a gimmick. dead yeast is natural. not animal based
How much would you have to eat though? Typical serving is a few grams.
@@welcomeback2mychannel I am sure it is OK to eat it once in a while but I see so many recipes using 1/2 cup to 1 cup and people sprinkling it on top of whole grains, tofu, vegetables... Even Dr Fuhrman is not hot about it. I was just wondering if there were some solid studies about it. I'll post the link from Jeff Novick but I understand people's suspicions clicking on links. Go to the John McDougall forum " of January 19 2013 to see Jeff Novick's answer.
www.drmcdougall.com/forums/viewtopic.php?f=22&t=34262
2 seconds into video. "This is the best video ever!"
Thanks for all your hard work, so I don’t have to. But I know the studies are there if I want to read them.
I had heard a lot about these different pathways cause I'd seen many interviews with doctor Longo. But I forgot what most of the acronyms stand for, so thanks for refreshing my mind.
What about taking Berberine instead of metformin?
Another home run video! Thanks.
Love that you’re always objective and entertaining!!
Thanks for the research.
Awesome video! I love how much information you’ve shared
I’m surprised you didn’t mention Berberine a natural supplement that is know at activate AMPK equally well if not better than Metformin
Thank you! Fun and informative video, as always.
This is a very interesting topic, I was happy to find your research on it.
You’re SOOO funny 🤣🤣-that ENDING!!!
Thanks for sharing Mic
Still in my thirties, and just hoping I get to test these someday....
Animal ag is destroying the planet so fast that I fear ecosystem collapse will actually be what determines our "longevity"....
Vegans need to be deeply concerned with the environment (everyone does) but more so *environmentalists absolutely need to adopt veganism!*
Enjoyable video buddy, keep it up!
It's kind of a myth that animal agriculture is bad though, people always say they take a lot of water, but a lot of the water they take is actually just peed out onto the ground. It's not like if they drink 100 gallons of water they just keep it the whole time. They only keep what they need to maintain body weight. Same with the whole methane argument, it's really not as bad as people say. The real pollution problem comes from China and India these days. Especially huge plastic issues. I would say though, pasture raised farming is preferred. I would love to get rid of any corporitization of the food system. It would help farmers be free and not in debt. Also just keeping animals in feeding lots is horrible. You have to understand though these studies on meat are limited, we don't actually know if eating meat is as bad as a lot of vegans say. Eating bad processed meat sure, but a lot of studies on meat are following people who also smoke and make a bunch of other bad lifestyle decisions. People who are vegan are usually more health conscious and don't smoke etc.
@@Hoppensagen you should look at the studies on land use.... they explain we could rewild an area the size of Russia back into natural biodiverse habitat, which would really help with both carbon absorption and stabilizing the climate. It would also help slow the mass extinctions already underway.
But really, it's the whole impact of all these things put together, not just one variable. Land is by far the big one when it comes to animal agg though.
People still act like we have no limits to our consumption and I still see people throw trash out the window and find it pretty much everywhere.
We are just too stupid to realize we're killing our beautiful planet through our everyday decisions, and food is the biggest factor in that. We get terrified over a bad cold spreading around, but can't see the very obvious things we've done that are making the ecosystem break down. And somehow we think we'll just move to Mars if it gets real bad, which is even more absurd.
I'm not sure we deserve this paradise and soon it'll be too late to do anything about the damage we've done
I learned something from this video and that is eat plant foods,workout and do a bit of cardio
Very, very insightful. Thank you so much for the hard work and time you put in these videos!
Lots of love!
Great review! You've got the brains to question this longevity super star! 👍
I love how excited you get when you talk about your research lol. Thanks so much for another great video!
A lot of great information well presented. Thanks.
I really enjoyed this video, I am grateful for the energy you put forward to create it. I learned a lot and also achieved a better understanding of information that I was familiar with. Thank you, Mic.
Great Vid as always Mic, I will definitely need to watch this one again as there is much to take in. Interesting about the height/ longevity connection.
I feel I just learned EVERYTHING from watching this video so congratulations to you.