Dr. Anderson, could you please provide information about the recommended time of day and dosage for taking Glutathione? Also, I am curious to know which form of Magnesium (citrate, malate, glycinate) is more effective when combined with Glutathione. I appreciate your videos; they are very educational! 😁
The problem I run into constantly is that hundreds of seemingly legitimate products, which claim to be "Liposomal" do not mention whether or not they've actually gone through the process of creating real liposomes. 'Cause apparently there are tons of manufacturers who simply add ingredients that COULD be liposomal, but as mere ingredients they don't result in any liposomes at all. Usually in these cases, they've added "phosphatidylcholine" (from sunflower oil) and "lecethin", as far as I know. Other manufacturers simply state that their product is Liposomal and that it has "phospholipids", with no mention of phosphatidylcholine or lecethin. However, by reading further on other sites and such I sometimes find that those compounds ARE listed for the same product. So I am clueless. The experts I've listened to just say "beware of phosphatidylcholine / lecethin", and that: "There must be phospholipids involved". So how on earth can I as a consumer ever know if there are any actual liposomes in my supplements? Any response would be much appreciated!
That's a really good point thank you for bringing it up. I would suggest consulting with a provider/doctor who uses those liposomal products regularly. They can point you to products and brands they know and trust are high quality. - Team Dr. A
Thank you so much for this great information, Dr. A. I was about to purchase some reduced glutathione, which, I have to assume is not one of the two , better absorbable ones. Now, I know what to look for.
Thank you for the informative lectures that you offer dr. , i believe that all the benefit free information freely will return back to you ,thanks again
Hi Dr. Paul, this is great content and very educational. Are we able to clip this content and post to our social media in the future? We will of course credit you.
What about the stability of liquid liposomal glutathione? Do you ask for data on stability since this form is likely to degrade rapidly vs other delivery formats?
In my area, I was able to get NOW glutathione 500mg with milk thistle extract & alpha Lipoic Acid in capsule. Any thoughts on how readily available this one can be?
What could be the reason why someone will react bad to liposomal glutathione and does glutathione can deplete other nutrients? Does low b1 can cause this type of issue?
You can have reactions to some compounds when the body starts processing toxins after dosing. Glutathione is a nutrient intensive antioxidant. I'm not sure about the B1. See some of the other Glut videos for more info - Team Dr. A
@@longyang888 yes. pls read below. I took the below text from the youtube video : th-cam.com/video/h5ULrcoSlKo/w-d-xo.html&ab_channel=Continual-G . Please read it in the whole. I talks everything about other supplements such as NAC, Liposomal glutathione, etc. Only Glyteine and Immunocal can raise intercellular glutathione. ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- NAC and glutathione supplements cannot increase cellular glutathione levels above homeostasis and there is no scientific basis as to why they should. NAC is only good for restoring glutathione levels following an acetaminophen (paracetamol) overdose. Cellular glutathione homeostasis is dictated by a feedback inhibition mechanism where glutathione modulates the activity of the enzyme that makes gamma-glutamylcysteine (Glyteine). Homeostasis becomes dysfunctional (low) in some genetic disorders, during aging, and in chronic diseases, where not enough Glyteine is made to produce sufficient glutathione to protect affected cells from oxidative stress. Glyteine is the only theoretical compound that can increase cellular glutathione levels (www.glutathionereporter.com). Any ability of whey to increase cellular glutathione is likely due to it containing small amounts of Glyteine bound to the lactoferrin and serum albumin fractions. This was known and published by the late founder of Immunotec (manufacturer of Immunocal), Gustavo Bounous in the early 1990s (see www.immparables.com/Research_Article_04.pdf). “The presence in the serum albumin fraction of glutamylcysteine groups (rare in food protein) and the specific intramolecular bond as related to the undenatured conformation of the molecule are considered to be key factors in the glutathione-promoting activity of the protein mixture”. But this seems to have been forgotten by Immunotec over the years and these days Immunocal is marketed as containing “bonded cysteine” but what it really is, is “bonded Glyteine”. So, you now have a choice, either buy Immunocal (undefined Glyteine content) or Continual G (410 mg Glyteine) beverage powder. Either way, both are probably going to be good for you. But NAC and glutathione and other non-Glyteine containing supplements will do nothing. Glutathione homeostasis is regulated by glutathione interacting with the enzyme (glutamate cysteine ligase, GCL) responsible for gamma-glutamlycysteine (Glyteine) synthesis. As cellular glutathione levels approach homeostasis this interaction slows down the production of Glyteine and consequently the production of glutathione. Therefore, the only theoretical substrate based approach to increasing glutathione above homeostasis is Glyteine which can enter the cell and be converted to glutathione by the non-regulatory control enzyme glutathione synthase. NAC just provides cells with cysteine which feeds into GCL and cannot theoretically increase cellular glutathione levels above homeostasis. As someone who authored a book on glutathione in order to explain to the general public the health benefits they can expect from increased glutathione you surely must recognize that to obtain those benefits, it is essential to elevate cellular glutathione concentrations above homeostasis. Lowered glutathione homeostasis is related to most medical conditions and aging. Clinical research has confirmed that Glyteine is bioavailable to rapidly (within hours) increase cellular glutathione levels above homeostasis, whereas there is no biochemical mechanism by which NAC should be able to and there are no clinical trials proving it can. If you are aware of any such report(s) please enlighten us. www.sciencedirect.com/science/article/pii/S2213231716303718
@@longyang888 Yes.. Please read below. I took this from other youtube channel hosted by Continual-G. It talks about all the other Glutathione and precursors any why something works and doesn't. NAC and glutathione supplements cannot increase cellular glutathione levels above homeostasis and there is no scientific basis as to why they should. NAC is only good for restoring glutathione levels following an acetaminophen (paracetamol) overdose. Cellular glutathione homeostasis is dictated by a feedback inhibition mechanism where glutathione modulates the activity of the enzyme that makes gamma-glutamylcysteine (Glyteine). Homeostasis becomes dysfunctional (low) in some genetic disorders, during aging, and in chronic diseases, where not enough Glyteine is made to produce sufficient glutathione to protect affected cells from oxidative stress. Glyteine is the only theoretical compound that can increase cellular glutathione levels (www.glutathionereporter.com). Any ability of whey to increase cellular glutathione is likely due to it containing small amounts of Glyteine bound to the lactoferrin and serum albumin fractions. This was known and published by the late founder of Immunotec (manufacturer of Immunocal), Gustavo Bounous in the early 1990s (see www.immparables.com/Research_Article_04.pdf). “The presence in the serum albumin fraction of glutamylcysteine groups (rare in food protein) and the specific intramolecular bond as related to the undenatured conformation of the molecule are considered to be key factors in the glutathione-promoting activity of the protein mixture”. But this seems to have been forgotten by Immunotec over the years and these days Immunocal is marketed as containing “bonded cysteine” but what it really is, is “bonded Glyteine”. So, you now have a choice, either buy Immunocal (undefined Glyteine content) or Continual G (410 mg Glyteine) beverage powder. Either way, both are probably going to be good for you. But NAC and glutathione and other non-Glyteine containing supplements will do nothing. Glutathione homeostasis is regulated by glutathione interacting with the enzyme (glutamate cysteine ligase, GCL) responsible for gamma-glutamlycysteine (Glyteine) synthesis. As cellular glutathione levels approach homeostasis this interaction slows down the production of Glyteine and consequently the production of glutathione. Therefore, the only theoretical substrate based approach to increasing glutathione above homeostasis is Glyteine which can enter the cell and be converted to glutathione by the non-regulatory control enzyme glutathione synthase. NAC just provides cells with cysteine which feeds into GCL and cannot theoretically increase cellular glutathione levels above homeostasis. As someone who authored a book on glutathione in order to explain to the general public the health benefits they can expect from increased glutathione you surely must recognize that to obtain those benefits, it is essential to elevate cellular glutathione concentrations above homeostasis. Lowered glutathione homeostasis is related to most medical conditions and aging. Clinical research has confirmed that Glyteine is bioavailable to rapidly (within hours) increase cellular glutathione levels above homeostasis, whereas there is no biochemical mechanism by which NAC should be able to and there are no clinical trials proving it can. If you are aware of any such report(s) please enlighten us. www.sciencedirect.com/science/article/pii/S2213231716303718
@@longyang888 Yes. please read below. i took the below from another video by Continous-G. NAC and glutathione supplements cannot increase cellular glutathione levels above homeostasis and there is no scientific basis as to why they should. NAC is only good for restoring glutathione levels following an acetaminophen (paracetamol) overdose. Cellular glutathione homeostasis is dictated by a feedback inhibition mechanism where glutathione modulates the activity of the enzyme that makes gamma-glutamylcysteine (Glyteine). Homeostasis becomes dysfunctional (low) in some genetic disorders, during aging, and in chronic diseases, where not enough Glyteine is made to produce sufficient glutathione to protect affected cells from oxidative stress. Glyteine is the only theoretical compound that can increase cellular glutathione levels (www.glutathionereporter.com). Any ability of whey to increase cellular glutathione is likely due to it containing small amounts of Glyteine bound to the lactoferrin and serum albumin fractions. This was known and published by the late founder of Immunotec (manufacturer of Immunocal), Gustavo Bounous in the early 1990s “The presence in the serum albumin fraction of glutamylcysteine groups (rare in food protein) and the specific intramolecular bond as related to the undenatured conformation of the molecule are considered to be key factors in the glutathione-promoting activity of the protein mixture”. But this seems to have been forgotten by Immunotec over the years and these days Immunocal is marketed as containing “bonded cysteine” but what it really is, is “bonded Glyteine”. So, you now have a choice, either buy Immunocal (undefined Glyteine content) or Continual G (410 mg Glyteine) beverage powder. Either way, both are probably going to be good for you. But NAC and glutathione and other non-Glyteine containing supplements will do nothing. Glutathione homeostasis is regulated by glutathione interacting with the enzyme (glutamate cysteine ligase, GCL) responsible for gamma-glutamlycysteine (Glyteine) synthesis. As cellular glutathione levels approach homeostasis this interaction slows down the production of Glyteine and consequently the production of glutathione. Therefore, the only theoretical substrate based approach to increasing glutathione above homeostasis is Glyteine which can enter the cell and be converted to glutathione by the non-regulatory control enzyme glutathione synthase. NAC just provides cells with cysteine which feeds into GCL and cannot theoretically increase cellular glutathione levels above homeostasis. As someone who authored a book on glutathione in order to explain to the general public the health benefits they can expect from increased glutathione you surely must recognize that to obtain those benefits, it is essential to elevate cellular glutathione concentrations above homeostasis. Lowered glutathione homeostasis is related to most medical conditions and aging. Clinical research has confirmed that Glyteine is bioavailable to rapidly (within hours) increase cellular glutathione levels above homeostasis, whereas there is no biochemical mechanism by which NAC should be able to and there are no clinical trials proving it can. If you are aware of any such report(s) please enlighten us.
Thank you for this!!!!! 🎉🎉❤
Dr. Anderson, could you please provide information about the recommended time of day and dosage for taking Glutathione? Also, I am curious to know which form of Magnesium (citrate, malate, glycinate) is more effective when combined with Glutathione. I appreciate your videos; they are very educational! 😁
I think, am not 100% but magnesium glycinate is the one you want💁♂️🤔
The problem I run into constantly is that hundreds of seemingly legitimate products, which claim to be "Liposomal" do not mention whether or not they've actually gone through the process of creating real liposomes. 'Cause apparently there are tons of manufacturers who simply add ingredients that COULD be liposomal, but as mere ingredients they don't result in any liposomes at all. Usually in these cases, they've added "phosphatidylcholine" (from sunflower oil) and "lecethin", as far as I know.
Other manufacturers simply state that their product is Liposomal and that it has "phospholipids", with no mention of phosphatidylcholine or lecethin. However, by reading further on other sites and such I sometimes find that those compounds ARE listed for the same product. So I am clueless. The experts I've listened to just say "beware of phosphatidylcholine / lecethin", and that: "There must be phospholipids involved". So how on earth can I as a consumer ever know if there are any actual liposomes in my supplements?
Any response would be much appreciated!
That's a really good point thank you for bringing it up. I would suggest consulting with a provider/doctor who uses those liposomal products regularly. They can point you to products and brands they know and trust are high quality. - Team Dr. A
Thank you so much for this great information, Dr. A. I was about to purchase some reduced glutathione, which, I have to assume is not one of the two , better absorbable ones. Now, I know what to look for.
Thank you for the informative lectures that you offer dr. , i believe that all the benefit free information freely will return back to you ,thanks again
Thank you -Team Dr. A
How about LipoMicel Matrix?
Hi Dr. Paul, this is great content and very educational. Are we able to clip this content and post to our social media in the future? We will of course credit you.
Would you say IM or IV has better absorption?
I've seen sublingual versions also...
Gamma-glutamylcysteine (glyteine) is the only one that raises glutathione above homeostatis
there is another guy on YT who claims there is no study which says these 2 forms are absorbed better.
What about glutathion creams and sprays?
What about the stability of liquid liposomal glutathione? Do you ask for data on stability since this form is likely to degrade rapidly vs other delivery formats?
what about aceytlecycstein? yes it is a precursor --how much is absorbed vs glutaghione ?
What about rectal administration of plain reduced glutathione?
😳
Thank you
In my area, I was able to get NOW glutathione 500mg with milk thistle extract & alpha Lipoic Acid in capsule. Any thoughts on how readily available this one can be?
What’s the brand that you said has a even better liposomal glutathione please
Researched Nutritionals Tri-Fortify Liposomal Glutathione Gel
Or
Aurora Lipo Glutathione
SHCGglutathione's liposomal I use that
How about sublingual glutathione sir?
What could be the reason why someone will react bad to liposomal glutathione and does glutathione can deplete other nutrients?
Does low b1 can cause this type of issue?
You can have reactions to some compounds when the body starts processing toxins after dosing. Glutathione is a nutrient intensive antioxidant. I'm not sure about the B1. See some of the other Glut videos for more info - Team Dr. A
Would like your comment on Continual-G [Glyteine®]. Is it a better form of Glutathione ? Thanks
Only thing that raises intercellular glutathione. Immunocal may do it as well because it also has bonded cysteine but not as good as Glyteine
@@gouthamreddy92 Does it mean that Glyteine is the most effective way to supplement ?
@@longyang888 yes. pls read below. I took the below text from the youtube video : th-cam.com/video/h5ULrcoSlKo/w-d-xo.html&ab_channel=Continual-G . Please read it in the whole. I talks everything about other supplements such as NAC, Liposomal glutathione, etc. Only Glyteine and Immunocal can raise intercellular glutathione.
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
NAC and glutathione supplements cannot increase cellular glutathione levels above homeostasis and there is no scientific basis as to why they should. NAC is only good for restoring glutathione levels following an acetaminophen (paracetamol) overdose. Cellular glutathione homeostasis is dictated by a feedback inhibition mechanism where glutathione modulates the activity of the enzyme that makes gamma-glutamylcysteine (Glyteine). Homeostasis becomes dysfunctional (low) in some genetic disorders, during aging, and in chronic diseases, where not enough Glyteine is made to produce sufficient glutathione to protect affected cells from oxidative stress. Glyteine is the only theoretical compound that can increase cellular glutathione levels (www.glutathionereporter.com). Any ability of whey to increase cellular glutathione is likely due to it containing small amounts of Glyteine bound to the lactoferrin and serum albumin fractions. This was known and published by the late founder of Immunotec (manufacturer of Immunocal), Gustavo Bounous in the early 1990s (see www.immparables.com/Research_Article_04.pdf). “The presence in the serum albumin fraction of glutamylcysteine groups (rare in food protein) and the specific intramolecular bond as related to the undenatured conformation of the molecule are considered to be key factors in the glutathione-promoting activity of the protein mixture”. But this seems to have been forgotten by Immunotec over the years and these days Immunocal is marketed as containing “bonded cysteine” but what it really is, is “bonded Glyteine”. So, you now have a choice, either buy Immunocal (undefined Glyteine content) or Continual G (410 mg Glyteine) beverage powder. Either way, both are probably going to be good for you. But NAC and glutathione and other non-Glyteine containing supplements will do nothing.
Glutathione homeostasis is regulated by glutathione interacting with the enzyme (glutamate cysteine ligase, GCL) responsible for gamma-glutamlycysteine (Glyteine) synthesis. As cellular glutathione levels approach homeostasis this interaction slows down the production of Glyteine and consequently the production of glutathione. Therefore, the only theoretical substrate based approach to increasing glutathione above homeostasis is Glyteine which can enter the cell and be converted to glutathione by the non-regulatory control enzyme glutathione synthase. NAC just provides cells with cysteine which feeds into GCL and cannot theoretically increase cellular glutathione levels above homeostasis. As someone who authored a book on glutathione in order to explain to the general public the health benefits they can expect from increased glutathione you surely must recognize that to obtain those benefits, it is essential to elevate cellular glutathione concentrations above homeostasis. Lowered glutathione homeostasis is related to most medical conditions and aging. Clinical research has confirmed that Glyteine is bioavailable to rapidly (within hours) increase cellular glutathione levels above homeostasis, whereas there is no biochemical mechanism by which NAC should be able to and there are no clinical trials proving it can. If you are aware of any such report(s) please enlighten us.
www.sciencedirect.com/science/article/pii/S2213231716303718
@@longyang888 Yes.. Please read below. I took this from other youtube channel hosted by Continual-G. It talks about all the other Glutathione and precursors any why something works and doesn't.
NAC and glutathione supplements cannot increase cellular glutathione levels above homeostasis and there is no scientific basis as to why they should. NAC is only good for restoring glutathione levels following an acetaminophen (paracetamol) overdose. Cellular glutathione homeostasis is dictated by a feedback inhibition mechanism where glutathione modulates the activity of the enzyme that makes gamma-glutamylcysteine (Glyteine). Homeostasis becomes dysfunctional (low) in some genetic disorders, during aging, and in chronic diseases, where not enough Glyteine is made to produce sufficient glutathione to protect affected cells from oxidative stress. Glyteine is the only theoretical compound that can increase cellular glutathione levels (www.glutathionereporter.com). Any ability of whey to increase cellular glutathione is likely due to it containing small amounts of Glyteine bound to the lactoferrin and serum albumin fractions. This was known and published by the late founder of Immunotec (manufacturer of Immunocal), Gustavo Bounous in the early 1990s (see www.immparables.com/Research_Article_04.pdf). “The presence in the serum albumin fraction of glutamylcysteine groups (rare in food protein) and the specific intramolecular bond as related to the undenatured conformation of the molecule are considered to be key factors in the glutathione-promoting activity of the protein mixture”. But this seems to have been forgotten by Immunotec over the years and these days Immunocal is marketed as containing “bonded cysteine” but what it really is, is “bonded Glyteine”. So, you now have a choice, either buy Immunocal (undefined Glyteine content) or Continual G (410 mg Glyteine) beverage powder. Either way, both are probably going to be good for you. But NAC and glutathione and other non-Glyteine containing supplements will do nothing.
Glutathione homeostasis is regulated by glutathione interacting with the enzyme (glutamate cysteine ligase, GCL) responsible for gamma-glutamlycysteine (Glyteine) synthesis. As cellular glutathione levels approach homeostasis this interaction slows down the production of Glyteine and consequently the production of glutathione. Therefore, the only theoretical substrate based approach to increasing glutathione above homeostasis is Glyteine which can enter the cell and be converted to glutathione by the non-regulatory control enzyme glutathione synthase. NAC just provides cells with cysteine which feeds into GCL and cannot theoretically increase cellular glutathione levels above homeostasis. As someone who authored a book on glutathione in order to explain to the general public the health benefits they can expect from increased glutathione you surely must recognize that to obtain those benefits, it is essential to elevate cellular glutathione concentrations above homeostasis. Lowered glutathione homeostasis is related to most medical conditions and aging. Clinical research has confirmed that Glyteine is bioavailable to rapidly (within hours) increase cellular glutathione levels above homeostasis, whereas there is no biochemical mechanism by which NAC should be able to and there are no clinical trials proving it can. If you are aware of any such report(s) please enlighten us.
www.sciencedirect.com/science/article/pii/S2213231716303718
@@longyang888 Yes. please read below. i took the below from another video by Continous-G.
NAC and glutathione supplements cannot increase cellular glutathione levels above homeostasis and there is no scientific basis as to why they should. NAC is only good for restoring glutathione levels following an acetaminophen (paracetamol) overdose. Cellular glutathione homeostasis is dictated by a feedback inhibition mechanism where glutathione modulates the activity of the enzyme that makes gamma-glutamylcysteine (Glyteine). Homeostasis becomes dysfunctional (low) in some genetic disorders, during aging, and in chronic diseases, where not enough Glyteine is made to produce sufficient glutathione to protect affected cells from oxidative stress. Glyteine is the only theoretical compound that can increase cellular glutathione levels (www.glutathionereporter.com). Any ability of whey to increase cellular glutathione is likely due to it containing small amounts of Glyteine bound to the lactoferrin and serum albumin fractions. This was known and published by the late founder of Immunotec (manufacturer of Immunocal), Gustavo Bounous in the early 1990s “The presence in the serum albumin fraction of glutamylcysteine groups (rare in food protein) and the specific intramolecular bond as related to the undenatured conformation of the molecule are considered to be key factors in the glutathione-promoting activity of the protein mixture”. But this seems to have been forgotten by Immunotec over the years and these days Immunocal is marketed as containing “bonded cysteine” but what it really is, is “bonded Glyteine”. So, you now have a choice, either buy Immunocal (undefined Glyteine content) or Continual G (410 mg Glyteine) beverage powder. Either way, both are probably going to be good for you. But NAC and glutathione and other non-Glyteine containing supplements will do nothing.
Glutathione homeostasis is regulated by glutathione interacting with the enzyme (glutamate cysteine ligase, GCL) responsible for gamma-glutamlycysteine (Glyteine) synthesis. As cellular glutathione levels approach homeostasis this interaction slows down the production of Glyteine and consequently the production of glutathione. Therefore, the only theoretical substrate based approach to increasing glutathione above homeostasis is Glyteine which can enter the cell and be converted to glutathione by the non-regulatory control enzyme glutathione synthase. NAC just provides cells with cysteine which feeds into GCL and cannot theoretically increase cellular glutathione levels above homeostasis. As someone who authored a book on glutathione in order to explain to the general public the health benefits they can expect from increased glutathione you surely must recognize that to obtain those benefits, it is essential to elevate cellular glutathione concentrations above homeostasis. Lowered glutathione homeostasis is related to most medical conditions and aging. Clinical research has confirmed that Glyteine is bioavailable to rapidly (within hours) increase cellular glutathione levels above homeostasis, whereas there is no biochemical mechanism by which NAC should be able to and there are no clinical trials proving it can. If you are aware of any such report(s) please enlighten us.
What if I use the dry powder form and nebulize it?
? CT Health ?
👍 - 👍