2-Minute Neuroscience: Psilocybin

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  • เผยแพร่เมื่อ 28 ม.ค. 2025

ความคิดเห็น • 332

  • @MrSchweppes
    @MrSchweppes 2 ปีที่แล้ว +127

    “Psychedelics are illegal not because a loving government is concerned that you may jump out of a third story window. Psychedelics are illegal because they dissolve opinion structures and culturally laid down models of behaviour and information processing. They open you up to the possibility that everything you know is wrong.”
    ― Terence McKenna

    • @katydid6920
      @katydid6920 2 ปีที่แล้ว +3

      The moralization is about who's drugs are you taking, not do you take drugs.

    • @timothytikker1147
      @timothytikker1147 4 หลายเดือนก่อน

      That, and they disempower so much of the corporate pharmaceutical industry...

  • @johnmike121
    @johnmike121 2 ปีที่แล้ว +15

    One dose earlier this month took me out of my depression rut and has changed my daily life very positively.

    • @johnmike121
      @johnmike121 2 ปีที่แล้ว

      @@katherinejames3336 I already know where to get anything I want

    • @TheCian19
      @TheCian19 3 หลายเดือนก่อน

      What dose did you have? ​@@johnmike121

    • @bakkila99
      @bakkila99 หลายเดือนก่อน

      How’s it going fellow Minnesotan lol. How are things holding up for you nowadays?
      I had a similar experience many years ago, but I’ve fallen back into other ruts since then in my life. One was cured by a DMT experience, and then a really bad abusive relationship and a lot of other bad trauma inducing scenarios has landed me into a pretty bad rut for the past year and a half. I’m currently trying to drag myself out of my hole and i think quitting alcohol is going to be a huge step towards that. I still take psychs here and there, but they are not what they use to be for me. Particularly mushrooms. The body load and other uncomfortable feelings really takes away from having a good experience. They aren’t super bad, but they aren’t really good either. I probably just need the right set and setting, and people around me, along with life’s cards to fall in and allow me to heal.

  • @arsenik_beats
    @arsenik_beats 4 ปีที่แล้ว +491

    Is it just me, or psychedelics are making a comeback in terms of research and public interest?

    • @neurochallenged
      @neurochallenged  4 ปีที่แล้ว +87

      It's not just you. There has been a substantial increase in research on psychedelics since the early 2000s.

    • @skinisdelicious3365
      @skinisdelicious3365 4 ปีที่แล้ว +42

      As they should

    • @bshef3424
      @bshef3424 4 ปีที่แล้ว +8

      How to Change your mind - Michael Pollan

    • @MRG978
      @MRG978 4 ปีที่แล้ว +36

      People are starting to realize that most pharmaceuticals are useless and the medicine has been hear for millions of years

    • @HippyMetalhead
      @HippyMetalhead 3 ปีที่แล้ว +4

      People are opening their minds and eyes

  • @alanbaker6311
    @alanbaker6311 8 หลายเดือนก่อน +7

    Psilocybin mushrooms healed me. I can't explain it but my experience has been spiritual and eye opening. I also started micro dosing. It really helped me get rid of depression and anxiety.

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      *Psychedelic saved my life from Depression and anxiety,all thanks goes to this mycologist who has been my guide during my journey on DMT,he also got other psychedelic stuffs in his store,shipping discreetly worldwide*

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      {He's on Instagram}

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      @Iyvoktrips }}}}}

  • @emmabeyza6036
    @emmabeyza6036 2 ปีที่แล้ว +64

    Psilocybin containing mushrooms saved my life. The drastically reduced my benzodiazepine withdrawal allowing me to quite illicit pill addiction after three years of heavy daily use before it would had became medically dangerous to quit. It has also helped me survive depression.

    • @ryancihet555
      @ryancihet555 2 ปีที่แล้ว +3

      The Trips I've been having really helped me a lot,I finally feel in control of my emotions and my future and things that used to be mundane to me now seem incredible and full of nuance on top of that I'm way less driven by my ego and I have alot more empathy as well

    • @ohmakure4716
      @ohmakure4716 2 ปีที่แล้ว

      @@ryancihet555 I feel the same way too. I put too much on my plate and it definitely affects my stress and anxiety levels. I am also glad to be a part of this community.

    • @aydenhaggarty318
      @aydenhaggarty318 2 ปีที่แล้ว

      Tripping is not all that bad but one has to find a good mycologist to teach you the right things you need to know

    • @helldragondante7604
      @helldragondante7604 2 ปีที่แล้ว +1

      Congrats

    • @benedict_spores
      @benedict_spores 2 ปีที่แล้ว

      @@ryancihet555 Look up ☝️☝️that handle; she’s got the best tips and stuff for big micro-dosing psych meds, DMT trips, psilocybin, mescaline, Ayahuasca and she ships swiftly too💯

  • @naagars7830
    @naagars7830 4 ปีที่แล้ว +389

    Eating mushrooms rn... wish me a good trip!

    • @z.a8847
      @z.a8847 4 ปีที่แล้ว +17

      How was it :P ?

    • @jrz9682
      @jrz9682 4 ปีที่แล้ว +33

      @@z.a8847 he never made it back 😂

    • @jrz9682
      @jrz9682 4 ปีที่แล้ว +13

      @@cosmic_love_5 deal lets see if he ever comes back 😂

    • @Ish_49
      @Ish_49 3 ปีที่แล้ว +7

      @@jrz9682 Y’all never came back

    • @vogelvogeltje
      @vogelvogeltje 3 ปีที่แล้ว +28

      NIGHTMARE NIGHTMARE NIGHTMARE NIGHTMARE

  • @teresavanhuyssteen4134
    @teresavanhuyssteen4134 2 ปีที่แล้ว +7

    Psilocybin helped me to wean and stop SSRI's with minimal withdrawal. As well as some other nasty substance addictions.

    • @mycogiggsonig9045
      @mycogiggsonig9045 2 ปีที่แล้ว

      The above name ⬆️⬆️⬆️ sells all kinds of products like change, Ayahuasca, salvia,DMT,LSD, shrooms, Xanax, golden teachers, chocolate bars, ketamine, GHB and lots more...

  • @Brainstorm69
    @Brainstorm69 4 ปีที่แล้ว +88

    There are (for the first time in decades) some really promising studies underway at both UCL and John Hopkins testing the efficacy of psilocybin on intractable depression. Very exciting times!

    • @cokax614
      @cokax614 4 ปีที่แล้ว +2

      Fun in the air

    • @Brainstorm69
      @Brainstorm69 4 ปีที่แล้ว +6

      @@cokax614 Must be interesting to take psilocybin under controlled lab conditions with scientists sitting there next to you. tripsitting.

    • @cokax614
      @cokax614 4 ปีที่แล้ว +1

      @@Brainstorm69 hahahah yes it does

    • @agape_99
      @agape_99 4 ปีที่แล้ว +2

      I believe it tho, along with brain-machine interference and simulations can reach our minds direcly, psychadelics are the other option with high potential to not just even therapies, but re-consruction of favores thought patterns patients desire in the future. I believe it bro

    • @agape_99
      @agape_99 4 ปีที่แล้ว

      Sorry for grammar mistakes, Im on phone half asleep

  • @Hayanomie
    @Hayanomie 4 ปีที่แล้ว +17

    Apparently it's stymied by interactions with anti depressants like Wellbutrin or effexor. In case someone experimenting tries psilocybin while on these, they may notice they have higher tolerance.

    • @abdulazizusman5060
      @abdulazizusman5060 2 ปีที่แล้ว

      Look up that handle TOP I also went through this but thanks to psychedelic microdosing I'm normal and okay again . He's got guidelines and products to overcome this disorder God bless you ( Dr imenherbal ).....

    • @theworkethic
      @theworkethic 2 ปีที่แล้ว +2

      SSRI’s limit psilocybin effects. Best to stay off anti depressants z

    • @Pyroific
      @Pyroific 2 ปีที่แล้ว

      so THATS why i need to eat an entire quarter to really feel it lol no wonder everyone thinks i take too much 😅

  • @jimmyfellows1836
    @jimmyfellows1836 3 ปีที่แล้ว +11

    Break it down further. Psilocin and Psilocybin are 4 hydroxy dmt and serotonin is 3 meo dmt. Hence why it works it's a booster of your natural serotonin.

    • @dunstanchecksin6005
      @dunstanchecksin6005 2 ปีที่แล้ว

      I thought, psilocin molecule is similar to serotonin and thus its just adding extra without using your own ones. Thus the no side effects

    • @zxgik
      @zxgik 2 ปีที่แล้ว +2

      @@dunstanchecksin6005 actually the structure isn't relevant (as highlighted in this short vid at least) - psilocin is a seratonin agonist. agonist means the chemical that binds to the receptor will cause an increase in the production of the molecule. so psilocin binding increases the production of your own seratonin molecules indeed

  • @jacobheaton8788
    @jacobheaton8788 3 ปีที่แล้ว +1

    Was blessed with a QP. Gonna do it over a few months

  • @zahitism6079
    @zahitism6079 4 ปีที่แล้ว +8

    Hi there. What about the Neurogenesis effects of psilocybin?

  • @boardingurban
    @boardingurban 3 ปีที่แล้ว +2

    Are you saying repeated use decreases/lessens the quantity 5HT2A receptors?

  • @ofroaddude5859
    @ofroaddude5859 4 ปีที่แล้ว +10

    Can you tell me what software do you use to make these videos?
    Thanks

  • @etcetera369
    @etcetera369 3 ปีที่แล้ว +10

    For anyone not doing it for the first time.. I recommend doing nothing while you trip. Sit in your living room with the TV off, maybe a puzzle to stimulate you. Thank me later lol

  • @lorasolomon5112
    @lorasolomon5112 2 ปีที่แล้ว +1

    Great share, love the video info...!

  • @jayfijan2959
    @jayfijan2959 2 ปีที่แล้ว +1

    is there a reason why psilocybin is inactive? i know that the polar nature of the phosphate group prevents it from crossing the blood brain barrier, but if that weren't an issue would it still be able to bind to the 5-HT2A receptor? or would the bulkiness of the phosphate group lower binding affinity?

    • @ethanmoore7357
      @ethanmoore7357 2 ปีที่แล้ว +1

      psilocybin has a low affinity for the 5HT2A receptor but has some minor affinity for 5HT2B

    • @jayfijan2959
      @jayfijan2959 2 ปีที่แล้ว

      @@ethanmoore7357 ah i see, thanks!

  • @jenniferthomas3875
    @jenniferthomas3875 2 ปีที่แล้ว

    Turn on, tune in, cheer up!

  • @TheSuccessExperiments
    @TheSuccessExperiments 6 หลายเดือนก่อน +1

    Is it like mdna?

  • @willbrown1220
    @willbrown1220 4 ปีที่แล้ว +6

    Amazing stuff, great work on the animations.

    • @fxdsxr45
      @fxdsxr45 2 ปีที่แล้ว

      Hi everyone, I am from the Arab world from Egypt. I am a grocery store 6 years old. I suffer from treatment-resistant depression. I want treatment with psilocybin.

  • @ADGO
    @ADGO 4 ปีที่แล้ว +30

    Did you somehow know I was just listening to podcasts with Paul Stamets? :)

    • @Burialofagod
      @Burialofagod 4 ปีที่แล้ว +4

      The youtubes ai algorithm knows

    • @pedrofuster9161
      @pedrofuster9161 3 ปีที่แล้ว +1

      Wow amazing to see you here

    • @emilia2373
      @emilia2373 3 ปีที่แล้ว

      Oh hello fellow Joe Rogan / Paul Stamets fans!

  • @jopmens6960
    @jopmens6960 2 ปีที่แล้ว +1

    I really dont get why psilocybin is showed in binding diagrams with receptors (elsewhere).. Altho 5-HT2a is also present outside the brain i think, ofc that is not the interesting part.. Psilocybin cannot cross the BBB barrier so why do they show it binding?

  • @Eric-yj5xg
    @Eric-yj5xg 4 ปีที่แล้ว +6

    why didnt you talk about neurogenesis?

  • @runningman7674
    @runningman7674 2 ปีที่แล้ว

    What is the down regulation of the ht2A receptor?? Where does this come from

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      *Psychedelic saved my life from Depression and anxiety,all thanks goes to this mycologist who has been my guide during my journey on DMT,he also got other psychedelic stuffs in his store,shipping discreetly worldwide*

  • @davidsweeney111
    @davidsweeney111 4 ปีที่แล้ว +2

    I wonder if they will make it legal in the UK again?

  • @karlakurucz127
    @karlakurucz127 2 ปีที่แล้ว +1

    But what about the effects on the heart? Specifically for those with congenital heart defects? ☹️

  • @user-ds2nj7zd6x
    @user-ds2nj7zd6x 3 ปีที่แล้ว +2

    AKA you can't get addicted to what when it won't affect you anymore after the third day you would have to increase your dosage so much everyday just to feel anything

  • @powerfulmanifestormentors
    @powerfulmanifestormentors 3 ปีที่แล้ว +3

    will there be an interaction if you drink but take anti depressants since it reacts to serotonin receptors ?

    • @thegalhorowitz
      @thegalhorowitz 3 ปีที่แล้ว +1

      yes seratonin syndrome, dont do it! This is medicine.

  • @GrowthChronicles_YT
    @GrowthChronicles_YT 2 ปีที่แล้ว +20

    There’s a lot of potential in psychedelics, I can’t wait to try any of them mushrooms specifically but it’s just so hard to find a reliable source over here, I’ll be glad if anyone can be of help

    • @Neto37375
      @Neto37375 2 ปีที่แล้ว +5

      Psychedelic drugs should be used when you’re in the right state of mind, a lot of people abuse them.

    • @Bryanclouds
      @Bryanclouds 2 ปีที่แล้ว

      Psilocybin containing mushrooms saved my life. They drastically reduced my benzodiazepine withdrawal allowing me to quit illicit pill addiction after three years of heavy daily use before it would had become medically dangerous to quit.

    • @GrowthChronicles_YT
      @GrowthChronicles_YT 2 ปีที่แล้ว

      @Jeffrey Hartwhere do I search is it on IG?

    • @GrowthChronicles_YT
      @GrowthChronicles_YT 2 ปีที่แล้ว

      @Jeffrey Hart
      Alright, I’m gonna check him out right now

    • @KelvinRosemark
      @KelvinRosemark 2 ปีที่แล้ว

      My crippling insecurity that was caused by emotional abuse in my childhood got cured on taking 5grams and also dramatically reduced the severity of my PTSD and uncovered very many repressed emotions I had

  • @skinisdelicious3365
    @skinisdelicious3365 4 ปีที่แล้ว +11

    That explains why my mushrooms didnt work, im immune to them from all the fuckin LSD xD

    • @FirstSynapse
      @FirstSynapse 3 ปีที่แล้ว +3

      Only if you ate the mushrooms just several days after your last LSD dose. The same would happen if you try to take LSD again the day after, you would need a much larger dose (double or triple the normal dose for the same effects). The tolerance goes away completely after a couple weeks.

    • @Stizz7777
      @Stizz7777 3 ปีที่แล้ว

      @@FirstSynapse I just ate shrooms yesterday so if I would eat more today would I feel. Them??

    • @FirstSynapse
      @FirstSynapse 3 ปีที่แล้ว +1

      @@Stizz7777 you would have to eat about triple the amount to feel similar effects and even then the experience wouldn't be the same. So you would be pretty much wasting your money and time.

    • @Stizz7777
      @Stizz7777 3 ปีที่แล้ว

      @@FirstSynapse how long would you recommend I wait till doing more??

    • @FirstSynapse
      @FirstSynapse 3 ปีที่แล้ว +2

      @@Stizz7777 well that depends. Your brain's tolerance will go to normal completely after about two weeks. You will get effects sooner than that but I personally wouldn't recommend doing shrooms more oftem than once a month, to maximise enjoyment and keep the "magic" of the experience. There are online calculators for tolerance after a dose.

  • @science_and_anonymous
    @science_and_anonymous 4 ปีที่แล้ว +1

    Once again, incredible video

  • @NoName-oj5pl
    @NoName-oj5pl 3 ปีที่แล้ว

    Good short video. Thank you

  • @Family__Guy_
    @Family__Guy_ 2 ปีที่แล้ว

    I ingested 4.9g of Tri Color Ecuadorian mixed with Amazon and no effect, purchased from a very reliable source; highly rated by psychonauts. Throughout my lifetime I have taken shrooms on 4 or 5 occasions, always ingesting three times more than the people I was with (and those people had quite the trips). I still have yet to experience a trip or effects of ANY kind.
    Is this level of tolerance common? Can there be other contributing factors as to why I need more? My diet wasn’t the greatest yesterday, so I will prepare with a cleaner diet a couple of days in advance of my next attempt. I will also take 10g, I think, perhaps using a tea.
    Any advice or criticism is welcomed.

    • @Family__Guy_
      @Family__Guy_ 2 ปีที่แล้ว

      Tried another 6g three weeks later and, with the experience I had, I would say that the effects were that of a ‘low dose’. Big difference from 4.9g to 6g, though.
      Maybe I’ll try 8g??

    • @rizzrightonInstagram
      @rizzrightonInstagram 2 ปีที่แล้ว

      check out⬆️to get this and also the trippiestt stuffs ever
      PS: be ready to be next to heaven

  • @user-ds2nj7zd6x
    @user-ds2nj7zd6x 3 ปีที่แล้ว +2

    Just like LSD after two or three days you probably won't feel anything everyday you take it the less and less effect you yet it's more of the weekend warrior type thing or once a month to get your mind and body back in sync or once-in-a-lifetime experience to see if it helps your life perception

    • @emilyjohnson8156
      @emilyjohnson8156 3 ปีที่แล้ว

      my dealer is the best mycologist plug I've ever seen,he grows the best psilocybin of different strains. Ya'll should go check him on Instagram @fran_sbull

    • @XxX_65
      @XxX_65 2 ปีที่แล้ว

      100% agree with you and listen to music and smoked thc with it will make a way better trip.

  • @BrianOSheaPlus
    @BrianOSheaPlus 2 ปีที่แล้ว

    Have you read any research about neuroplasticity and neurogenesis caused by psychedelics, as treatments for brain injuries and neurodegenerative diseases? I have been looking for clinical trials in these areas, but have not found many.

    • @elizabethjones6960
      @elizabethjones6960 2 ปีที่แล้ว

      i recommend him he's trustworthy he ship to any location man he got all kinds of psychedelic dmt LSD microdosing shrooms

    • @elizabethjones6960
      @elizabethjones6960 2 ปีที่แล้ว

      They're on INSTAGRAM

    • @elizabethjones6960
      @elizabethjones6960 2 ปีที่แล้ว

      Trip_world1_
      ??

  • @deadbeats4894
    @deadbeats4894 2 ปีที่แล้ว +4

    Psilocin is ineffable. Does wonders for treatment resistant anxiety/depression. Short term. I love psilocin.

    • @Raye-ml1hx
      @Raye-ml1hx ปีที่แล้ว

      I will refer you to online store I got mine stuff

    • @Raye-ml1hx
      @Raye-ml1hx ปีที่แล้ว

      They are on Instagram and telegram

    • @Raye-ml1hx
      @Raye-ml1hx ปีที่แล้ว

      @Pham_smart11

  • @MartyBoyRN23
    @MartyBoyRN23 2 ปีที่แล้ว +1

    Hopefully one day we can figure out how psilocin causes these mystical, sometimes ineffable experiences. Gotta be more than just serotonin receptor excitation.

  • @tpotturner101
    @tpotturner101 3 ปีที่แล้ว +6

    It's very safe ... in controlled amounts. Other wise you're gonna ride a wave you don't want to surf. Unless you know.

  • @BC___1
    @BC___1 3 ปีที่แล้ว

    I was taking seroquel at night 25mg for a couple years. I heard it affects that receptor. I've been off it for about a month now but is there a certain amount of time that needs to pass before that receptor goes back to default?

    • @thegalhorowitz
      @thegalhorowitz 3 ปีที่แล้ว +1

      they say two weeks but Im sure its different for everyone… Might have curbed your sensitivity. Take your time and keep trying till you feel it! ( lot of questions like this on reddit !)

  • @MessyMaj
    @MessyMaj 4 ปีที่แล้ว +1

    So if I take mushrooms 3 days later Am I gonna have a reduced acid trip or is it a maybe?

    • @taylordurden8470
      @taylordurden8470 4 ปีที่แล้ว +1

      You’ll still have a potent trip but waiting a full week resets tolerance to zero.

    • @MessyMaj
      @MessyMaj 3 ปีที่แล้ว

      @@taylordurden8470 Thanks

    • @cindybowen871
      @cindybowen871 3 ปีที่แล้ว

      I have a plug on ï..ğ...

    • @cindybowen871
      @cindybowen871 3 ปีที่แล้ว

      Psyc_dimensions got all psilocybin products 🍄🍫you need and ships discreetly also..

  • @Rg-es9kv
    @Rg-es9kv 4 ปีที่แล้ว +14

    ok il start these comments off reasonably, the whole world should take this and disassociate in order to better understand how we are controlled by our mammalian brains, and only through disassociation we the self can we achieve a truly harmonious world free of pain

    • @cesarcdx
      @cesarcdx 4 ปีที่แล้ว

      Better without drugs.

    • @Rg-es9kv
      @Rg-es9kv 4 ปีที่แล้ว +2

      ​@@cesarcdx yes but that takes huge cultural reform that isnt going to happen unless some sort apocalypse strikes us, yes if we all read the bhagavad gita then we wouldn't need this but since that is not going to happen, induced dissociation of the adult population would be a fantastic way to improve the world.

    • @kitscollective
      @kitscollective 4 ปีที่แล้ว

      way to go R g

    • @agape_99
      @agape_99 4 ปีที่แล้ว +5

      You can do it with improving your power of consciousness over your brain mechanism and establish it as a diciplin. Rage against uncontrolled impulses! Rage against the (biological) machine!

  • @vision10345
    @vision10345 4 ปีที่แล้ว +1

    Does psilocybin go bad. I hear it will last forever then I heard a year. I want to store some for the future. Anyone know? I appreciate the help

    • @alexkennedy9600
      @alexkennedy9600 4 ปีที่แล้ว

      I wouldn't plan it but what I did was keep a quarter of dried shrooms potent in side double ziploc bags use your knowledge

    • @vision10345
      @vision10345 4 ปีที่แล้ว +3

      @@alexkennedy9600 all jars. No plastic for anything. Degrades to much. Thanks you.

    • @youngknowledgeseeker
      @youngknowledgeseeker 4 ปีที่แล้ว

      Sorry bro, you’re gonna have to Google it or ask a professional on fungi. But, and I’m no expert nor should you listen to me, I heard that fresh mushrooms last about a week, and dried mushrooms last anywhere from six months to over a year depending in what and where you store it (vacuum sealed bag, in a cool/not humid, sanitized dark place)

    • @vision10345
      @vision10345 4 ปีที่แล้ว

      @@youngknowledgeseeker absolutely always research. Want to see what others say. This is still not fact in most places. Research is still ongoing everyday.

  • @obuyWw
    @obuyWw 4 ปีที่แล้ว +2

    concise and clear!! but what about Baeocystin? I read that shrooms also contain this apart from the two you mentioned.

    • @jamesisaac5587
      @jamesisaac5587 3 ปีที่แล้ว

      I get the best psychedelic products from @mycoallen check out her page on Instagram for the best quality mushrooms, dmt and mdma. @mycoallen
      He ships discreetly too he also got tips for you.

  • @Bot-tm7hs
    @Bot-tm7hs ปีที่แล้ว

    Ok but what happens after it binds to the receptor?

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      *Psychedelic saved my life from Depression and anxiety,all thanks goes to this mycologist who has been my guide during my journey on DMT,he also got other psychedelic stuffs in his store,shipping discreetly worldwide*

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      {He's on Instagram}

  • @hebrewwolf6540
    @hebrewwolf6540 4 ปีที่แล้ว +2

    How to acquire Psilo?

    • @cantavoidtrite
      @cantavoidtrite 4 ปีที่แล้ว

      Denver has decriminalized it.

    • @emilyjohnson8156
      @emilyjohnson8156 3 ปีที่แล้ว

      my dealer is the best mycologist plug I've ever seen,he grows the best psilocybin of different strains. Ya'll should go check him on Instagram @fran_sbull

  • @povtravelsadventures9281
    @povtravelsadventures9281 3 ปีที่แล้ว

    Just took my first micro dose
    capsule. How long does it kick in?

  • @jesipohl6717
    @jesipohl6717 4 ปีที่แล้ว +3

    do more on psilocyn, do some hypotheticals, there are plenty of hypotheses to draw from.

  • @saravargas31
    @saravargas31 ปีที่แล้ว

    These are great videos. However, there are multiple layers to this, and it is ***not*** definitive that Psilocin (metabolite of Psylocybin) really executes its effects through only 5HT2A receptors. That oversimplifies the picture of what's really going on; which really, still remains unknown. More papers are coming out this year challenging this hypothesis of 5HT2A receptors being the be-all and end-all of Psilocin effects. There is certainly something really interesting going on in terms of the mechanism(s); 5HT and Psilocin do not seem to affect cell types in the same way even though they both act through the same receptors -This is a fair assumption that should also be challenged. This is the day and age of Psychedelics!!! So much research being done with the potential to change gov. policy and change people's lives!

    • @EtukEsther
      @EtukEsther ปีที่แล้ว

      I get my psychedelics and microdosing stuff from an online store where I got my own his on Instagram and also on Telegram with the below handle

    • @EtukEsther
      @EtukEsther ปีที่แล้ว

      *Mycopete.*

  • @rickharold7884
    @rickharold7884 4 ปีที่แล้ว

    Interesting. Thx

  • @martymoody2501
    @martymoody2501 2 ปีที่แล้ว

    Watching this while I'm tripoing balls

  • @thegalhorowitz
    @thegalhorowitz 3 ปีที่แล้ว +1

    people commenting that they take it with ssri and alcohol… you ruin it for the rest of us. This is serious medicine and we need it to be legal, dont get seratonin syndrome on us

  • @SHMUPS
    @SHMUPS 3 ปีที่แล้ว

    so its an SSRI?

    • @ashleyhenry1602
      @ashleyhenry1602 3 ปีที่แล้ว

      Follow up this dude I ordered from on Instagram @ vestertripps. He got shrooms, chocolate bars, LSD,DMT and other dope psychy products ..

    • @aspiresk8boarding
      @aspiresk8boarding 2 ปีที่แล้ว

      Nope it blocks production of serotonin. That’s why it makes u feel light and open minded. Taking a lot will give the high serotonin effects and distort brain energy production and start tripping hard

  • @TH-bj1pb
    @TH-bj1pb 4 ปีที่แล้ว +1

    Lsd has some similar effect as psilocybin I would have said, rather than the opposite

  • @Kat31017
    @Kat31017 4 ปีที่แล้ว +1

    Interesting

    • @jamesisaac5587
      @jamesisaac5587 3 ปีที่แล้ว

      I get the best psychedelic products from @mycoallen check out her page on Instagram for the best quality mushrooms, dmt and mdma. @mycoallen
      He ships discreetly too

  • @FBI-ed9ku
    @FBI-ed9ku 4 ปีที่แล้ว +2

    UT Brainstorms??

  • @heytherenordic7230
    @heytherenordic7230 3 ปีที่แล้ว +3

    The downside for me is that I have dissociation disorder from trauma and psilocybin makes it worse, and it even triggers it for people that doesn’t have this disorder from before.

    • @IdlanRafiqi
      @IdlanRafiqi 3 ปีที่แล้ว +5

      Face your traume. If you know, it is a tool to bring your inner demon and trauma. Whatever you do, you need to solve it, in order to find peace with yourself.

  • @Godstepsofpromises
    @Godstepsofpromises 3 ปีที่แล้ว +1

    Psilocybin is not a drug it's being used in University of Washington treating a lot of PTSD in soldiers wouldn't you be proud about that I love my veterans.

  • @fumarate1
    @fumarate1 3 ปีที่แล้ว +5

    I notice if I've done high emounts of Magic mushrooms the pcilocybin stays in your system for ages,symtoms like hot sweats,hot flushes,tremors,white flash in eyes,anxiety,feeling sendimental weeping.

    • @carlitocouture8640
      @carlitocouture8640 3 ปีที่แล้ว +1

      Currently feel like I’ve been going through this, hot flashes through the day, night sweats, also hear a weird ringing from time to time

    • @fumarate1
      @fumarate1 3 ปีที่แล้ว

      @@carlitocouture8640 where you taking lots of them?

    • @carlitocouture8640
      @carlitocouture8640 3 ปีที่แล้ว

      @@fumarate1 i would usually take 3.5 almost a week apart

    • @fumarate1
      @fumarate1 3 ปีที่แล้ว

      @@carlitocouture8640 probably to much.

    • @carlitocouture8640
      @carlitocouture8640 3 ปีที่แล้ว +1

      @@fumarate1 just scooped another eighth bar today, definitely going to limit myself from now on thanks for the reply

  • @basiclee5770
    @basiclee5770 2 ปีที่แล้ว

    the chemical structure of psilocin looks EXACTLY like serotonin

  • @tnijoo5109
    @tnijoo5109 3 ปีที่แล้ว +1

    Rapid tolerance. Bummer

  • @laugh4life631
    @laugh4life631 3 ปีที่แล้ว +4

    Don't do drugs kids! Except mushrooms! Definitely do mushrooms!

    • @bubbyboi3696
      @bubbyboi3696 3 ปีที่แล้ว +1

      do you actually know the effects of psilocybin on a developing brain?

    • @laugh4life631
      @laugh4life631 3 ปีที่แล้ว

      @@bubbyboi3696 does going picking in my early teens and eating them myself count as knowing?

    • @bubbyboi3696
      @bubbyboi3696 3 ปีที่แล้ว

      @@laugh4life631 yes I would like to hear your experience with the long term effects of it on your brain.

    • @laugh4life631
      @laugh4life631 3 ปีที่แล้ว

      Please elaborate on what you mean! Am I a dribbling mess or am I more in tune with the real world? They grow out the ground! They are the biggest living organism in the world! They help with depression and anxiety! They are a potential unlimited food supply! They are the bin men of the planet! Watch Fantastic fungi it's amazing! Alcohol and cigarettes are the devil and kill more people than all recreational drugs!

    • @bubbyboi3696
      @bubbyboi3696 3 ปีที่แล้ว +1

      @@laugh4life631 yes I mean have you see. any negative effects on your brain like any issues with schizophrenia or any issues on your short or long term memory. stuff like that

  • @redwizxrd
    @redwizxrd 2 ปีที่แล้ว +1

    watching this on shrooms rn

  • @nealkelly9757
    @nealkelly9757 4 ปีที่แล้ว +3

    So it destroys receptors? Scary

    • @simplyvibinn5417
      @simplyvibinn5417 4 ปีที่แล้ว

      it doesnt

    • @craigmoyle2924
      @craigmoyle2924 3 ปีที่แล้ว

      Modulates receptors or resets receptors provided you space doses apart once a week maybe

    • @Liter4lly_Nobody
      @Liter4lly_Nobody 3 ปีที่แล้ว

      @@abella11 1:36 it's possible. Like people who use some substances to increase their testosterone level (in order to get ripped faster) often suffer from gynecomastia and their testes become smaller. Their organism tries to protect from such large amounts of this hormone and stops producing it. Psilocybin may couse something like that with other hormones but I never heard of it so maybe this process have little impact on the body.

    • @lykveekk1749
      @lykveekk1749 3 ปีที่แล้ว

      Jeremyco34 on Instagram has quality DMT compounds, LSD , choc
      olate bars they also grows and sells mushrooms 🍄

  • @beetlejuice4693
    @beetlejuice4693 3 ปีที่แล้ว +1

    Tripping

  • @derekaugust872
    @derekaugust872 2 ปีที่แล้ว +1

    Nope. It’s actually melts your brain. That’s why you get so hot on it.

  • @leonardplanckiii998
    @leonardplanckiii998 2 ปีที่แล้ว +1

    What happens when shrooms don’t work? Is the brain broke?

  • @jordanlangebein2342
    @jordanlangebein2342 4 ปีที่แล้ว

    Watching this video after munching some shroomies

    • @ChaosBW
      @ChaosBW 4 ปีที่แล้ว +1

      Wow way to ruin your high

  • @LEPRECHADOS
    @LEPRECHADOS 3 ปีที่แล้ว

    I´m high now on this lol

  • @bluewater8955
    @bluewater8955 3 ปีที่แล้ว

    Haha this video is so trippy.

  • @olorin4317
    @olorin4317 11 หลายเดือนก่อน +1

    More like silly psy-bean am I right? …I’ll show myself out.

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      *Psychedelic saved my life from Depression and anxiety,all thanks goes to this mycologist who has been my guide during my journey on DMT,he also got other psychedelic stuffs in his store,shipping discreetly worldwide*

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      {He's on Instagram}

  • @Reallys-l8o
    @Reallys-l8o 10 วันที่ผ่านมา

    125

  • @lucya7223
    @lucya7223 4 ปีที่แล้ว

    So you can get fried off of LSD, but just not trippin about that though

  • @looneycrow7978
    @looneycrow7978 4 ปีที่แล้ว

    Old study

  • @victorrubennavarrocortes739
    @victorrubennavarrocortes739 3 ปีที่แล้ว +2

    And another one talking through scientific mindset, which is exactly the opposite of what mushrooms are.
    STOP CALLING THIS SACRED MEDICINE A DRUG!!

    • @willr7849
      @willr7849 3 ปีที่แล้ว

      Drug: un
      a medicine or other substance which has a physiological effect when ingested or otherwise introduced into the body.
      By definition it’s a drug, doesn’t mean it’s bad, most medications are derived from plants fungus, sometimes even venom.

  • @peterschnack3518
    @peterschnack3518 11 หลายเดือนก่อน

    Danske pensionister i Fuengirola

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      *Psychedelic saved my life from Depression and anxiety,all thanks goes to this mycologist who has been my guide during my journey on DMT,he also got other psychedelic stuffs in his store,shipping discreetly worldwide*

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      {He's on Instagram}

    • @AlexDestiny-o4b
      @AlexDestiny-o4b 6 หลายเดือนก่อน

      @Iyvoktrips }}}}}

  • @martymoody2501
    @martymoody2501 2 ปีที่แล้ว

    Wow........... I'm gone. Haha stay away kids shrooms are not for kidsssdsss

  • @abdulazizusman5060
    @abdulazizusman5060 2 ปีที่แล้ว

    Look up that handle TOP I also went through this but thanks to psychedelic microdosing I'm normal and okay again . He's got guidelines and products to overcome this disorder God bless you ( Dr imenherbal ).....

    • @elizabethjones6960
      @elizabethjones6960 2 ปีที่แล้ว

      i recommend him he's trustworthy he ship to any location man he got all kinds of psychedelic dmt LSD microdosing shrooms

    • @elizabethjones6960
      @elizabethjones6960 2 ปีที่แล้ว

      They're on INSTAGRAM

    • @elizabethjones6960
      @elizabethjones6960 2 ปีที่แล้ว

      Trip_world1_
      ??