Be careful. It helped me too overall but you know the rumor about like people thinking they r a glad of orange juice and then never recovering. I got very close to that in 2020. I stayed away for a week 04/28/20 - 05/08/20 and I didn’t come back to reality until July 3rd. I had taken a gel tab . Just one. I puked 30min after I took it and I could tell it was gonna be a wild ride. It was. I had full psychosis. I’m recovered now. Fully recovered I have a job. Been in a three year relationship. Found real God . (I know the spiritual aspect if very all connected which is still true it’s just that Jesus is the true God) idk anyways… Be careful!!! I still smoke pot. I take lithium now too it’s a medicine.
@maryrosehopkins I took 7 gels last week and 4 the week before that. I'm sorry, but unless you're predisposed to schizophrenia, you are completely and utterly full of shit.
I’ve tried LSD a few times with mostly positive experiences. However I had a very bad trip a few days ago. Mine lasted over 24 hours of sheer paranoia and fear, the likes of which I wouldn’t wish on my worst enemy. My body was completely numb and I felt the extreme need to want to hurt myself and others. I somehow managed to calm down by drinking herbal tea, listening to soft music and talking with a suicidal hotline. If you ever try this drug, make sure you start with a very low dosage, have zero responsibilities and have a trip-sitter with you for at least 8 hours.
this is the main problem with LSD, one bad trip and it can fuck you up in the head quite badly, it happened to me as well and I think I still have "ghosts" of that bad trip in my personality, looking forward for healing myself this year.
Yo what does it feel like normally? Someon on another vid jus told me Puff the Magic Draggon is about LSD. Wow how inocent I am for a 36 year old. I still to this moment that this other person said this took that little tune to be about a magic Godzilla if you will. Cause Puff the magic dragon lived by the see. Hmmm sounds like Godzilla to me but of course a magic 1 as he's the macinations of a 4 year old.
@ultragd69 It is a drug, sure it may not be as destructive as meth, but, every addict will be irresponsible and, if they don't get a good high, they'll try harder drugs
@@neurochallenged pls tell me if i use lsd havily everi day for a month so i have very little 5-HT2A receptors, can i get them back, and does a shortige of this receptors cause long teem learning and memorizing skils (cognitive functions) pls tell me i realy wanna know
Amazing videos.. I m just 15 years old and your videos inspired me to learn out of textbook. I literally have a book filled with just your videos notes pls keep uploading and u r doing a great job keep it up
@@ike2938 depends on dosage and state of mind when taking the drug. Crucially though, it’s not addictive and does not have a significant physiological effect in the same way heroin/cocaine does
@@ike2938 well that depends on what country you live in. but it’s fairly easy buy online through the dark web/tor and get it shipped to where you live. Either that or find your local drug dealers and ask them
The perceptional distortion can be one of my favorite parts of taking lsd it's so funny how a shadow cast from something can change what your seeing and idk so hard for me to put it into words But I much prefer mushrooms over lsd
I disagree,, personally i prefer LSD over mushrooms.. to me the best description i can come up with is LSD is a cleaner trip Mushrooms are a heavy body trip and makes me nautious sometimes and i yawn alot on mushrooms and feel lethargic where LSD i am energized and alot more happy
@@danparts9333 I personally find that the comedown from LSD can be uncomfortable while mushrooms generally ease you back into sobriety. I think most of the discomfort from LSD comes from the vasoconstriction which leads to you feeling cold and clammy.
*Psychedelic definitely have undeniable benefits to deal with PTSD,ADDICTION,TRAUMA AND DEPRESSION ETC.The experience gave me freedom.I was Able to get shrooms,dmt,edibles,lsd etc from this licensed mycologist who ships to my location without hassel*
Hello I'm a person on acid rn um about 7hrs ago I had 2 brownies and a tab the rest had been kinda blankish but so many thoughts go through your brain. Just wanna say this... AMAZING...... but you have to be in good guidance of positive thoughts. The rest is your immaagunatikn See you in 12hours Edit: listen to Top Hat - Al Bowlly You're welcome.
One of the most transformative experiences of my lifetime, forever changed my reality. LSD’s power can not be understated, the insights that can be gained are immense. It’s been nearly 25 years since the last trip, still remember it like yesterday. Experiment responsibly ☺️
@@aleksandrzhilkin4800transformative experiences stick with you bro she wouldn’t need to keep doing it like a junkie to keep having transformative experiences a lot of people are good with just 1 experience like that and they are set
@@aleksandrzhilkin4800 I believe he didn't see a need for it. In my personal experience I've used LSD multiple times. It has helped me develop more cognitive perspectives of other people and develop more sympathy for people. I was kinda self centered back then. After those times, I felt like using the drug would be pointless.
Is it like weed at all? the comments make it to me sound kinda like THC in what happens if you get out of hand. But hmmm maybe CBD like trip if you do it right?
Then it dawns on you: “Of course, I’m LSD. I am consciousness. I am imagining myself. I am whatever I conceive myself to be because there is nothing outside my endless Mind.”
Generally speaking it's pretty enjoyable, but it's not until you have more difficult experiences that you begin making real progress. It's like calluses on a guitarists finger, you gotta feel the burn
It's not trying to explain how it feels it's trying to explain how it works on a neurological level to the best science understand right now. Don't be so condescending.
Are there any negative implications of a downregulation of the 5-HTP2A receptor on one’s overall mood or baseline or anything else? I wonder this in the case of microdosers who dose small amounts every 2-3 days.
That's a good question. There has been some speculation that 5-HT2A downregulation might be linked to therapeutic effects, but it's just speculation at this point as there's not much data on it. The mechanism of microdosing (as well as the effectiveness) is still pretty unclear.
In my few years of experience I haven't had any negative experience with downregulation. In fact, after a trip the downregulation takes place in much greater fashion than with microdosing. Some suggest that receptor downregulation caused by microdosing is minimal to none. In high (trip) doses it definitely takes place and after trips most report feeling much better and their psychological condition improve drastically. After my first trip I felt great for the next few months, better than ever in my life before. I don't think it's caused by downregulation though. I think this effect is just a 'side effect', that doesn't have to do anything with the actual therapeutic psychedelic effects.
3 Hits for my first time. 1- Everything is real. Everyone is Real. Life isn’t the same. You see things and people differently. 2- Don’t expect anything at all. Just Go for the ride. When doing any kinda of God Particles/ Hallucinating “ Drugs”. EMBRACE IT. Stop worrying, don’t think about anything. Have No noises, Background noises or perhaps music that is Not violent. Enjoy your first time. 3- The come down sucks, the let go is horrible. But don’t let it scare you, just take your time. If you don’t have LSD (it’s proper name) for MONTHS. Then fine. Just cope. But personally if you really wanna delve into that, Have a sheet. Or Droplets. And then fry yourself once. (But have a friend who is semi-fried or Still capable). Your safety is with Dosing. And Mentality
i love the experience, He got magic mushroom, Lsd, Dmt, microdose, and other psych as well... My order for penis envy and chocolates bar and all kinds of weeds arrived last week
What is the major differences between SSRI serotonin activation compared to LSD? Why LSD can induce hallucination with serotonin receptors activation, but SSRI did not? Is SSRI cannot activated 5ht2a receptors or there is other major factors that cause these differences.
One thing is that the mechanism is different; SSRIs are inhibiting the reuptake of serotonin, not binding to serotonin receptors. But the question still remains of why the increased serotonin levels induced by SSRIs don't elicit similar effects to LSD. The answer is that no one is sure yet, but one hypothesis is that LSD prompts some change in the conformation of the serotonin receptor that influences how the receptor interacts with other cellular constituents. According to this idea, there's something unique about the structure of LSD that causes the serotonin receptor to respond differently to it than it would to the increases in endogenous serotonin levels that SSRIs would cause.
A key factor is also the much greater binding affinity of LSD to the receptor. LSD is preferred over serotonin itself, the natural ligand! The receptor prefers LSD, if you like.
Also, there are two different pathways activated by the receptor, the G protein pathway and beta arrestin. Serotonin activates the g pathway more, LSD the beta arrestin. Forgive my shocking spelling.
Awesome question though. They say the Nobel prize is in the question and not the answer, I think this is one of those questions. Now you just gotta find out the answer and collect that Nobel!
I've heard a lot of tripping stories, and they are very exciting, i would love to try magic mushrooms but I can't easily get some, Is there any realiable source I can purchase from??
I have a general question about making TH-cam video!! Please answer.. Can we take picture from google search and use it in our video to explain the stuff?? (With reference link on it)
Hi Safoora, you should only use images that the creator has indicated are OK for you to reuse. I use search.creativecommons.org/to search for images that I can reuse if I'm looking for an image to use in my videos (most of them I create on my own, though).
mad ophelia probably my first but then again... one day I was given a red star microdot and I was already running at a thousand miles per hr on e and speed. That was a night to remember, forever!
After taking a dose of 200 ug and having a good trip, next day do anyone have intense dreams and wake up every few hours 🤔.. and I am a extrovert and love to socalize but for few weeks I feel off and nervouse and after that I am back to normal ...?
@@xavierthe_elfeduardo9699 bc whats the negative side effects of lsd? Did u not watch the video? Doing it safely has zero adverse health effects and its non addictive. Drugs aren't all bad bud
@@sinxsideways5900 don’t spout nonsense like “lsd has no adverse side effects”, that’s not true at all, and that’s not even what the video said. I love acid but cant stand misinformation like this.
What about the point I read about it getting trapped in the receptor causing the body to absorb it to break it down leading to why it lasts so long... Mine went 12 hours.
Does lsd affect people in depression? I started smoking marijuana and decided to suicide a few months back and still im depressed and i started medications but i dont think its helping so i wanna try anything that will make me happy. I am not a bad person but my condition got so worse that i am lost so lost that every day is new and i dont remember much about past 😕💔
it may not have physical effect but it has mental effect which is unpredictable and varies from person to person.Don’t get fucked up and loose your sense of morality just to be cool. :)
Yea this doesn't happen unless ur wreckless with it bud. Do ur research on dosage and set and setting. Ur environment controls ur trip and ur state of mind. These drugs have also been proven to be the best treatment for depression and addiction to other substances. No one has ever gone crazy bc of LSD and no one has ever OD'd on it bc its practically impossible to do so
@@MahmudulHasan-gp9qm where is ur factual information on this. The person who synthesized it said it is one of the most least toxic substances on the planet.
@@MahmudulHasan-gp9qm what are u talking about. Its literally science. I can provide u with a ton of facts. Irresponsible ppl domt make a drug bad thats stupidity and that can make anything harmful. Explain how it's harmful bc u have yet to do so
I get my from an online store his got shroom, psychedelic and microdosing products well refined also ships to anywhere discreetly, can also guide you on anything.
Because even though we don't understand exactly what it does in the brain to produce its effects, we do know from animal research and about 80 years of human use that it isn't linked to life-threatening complications.
LSD is a partial agonist on 5-HT2A? I doubt this, LSD has strong affinity to it, which makes it an agonist. But LSD has partial agonism on a dopamine receptor, I think it's D3.
LSD has high binding affinity for 5-HT2A, but lower activation efficacy than other 5-HT2A ligands. I relied on a 2016 study (see reference below) for information on affinity, potency & efficacy. From that study: "LSD and psilocin were 5-HT2A receptor partial agonists, with 28% and 16% activation efficacy, respectively, whereas all of the other compounds presented higher 5-HT2A receptor activation efficacies..." Rickli A, Moning OD, Hoener MC, Liechti ME. Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens. Eur Neuropsychopharmacol. 2016 Aug;26(8):1327-37. doi: 10.1016/j.euroneuro.2016.05.001. Epub 2016 May 20.
*Psychedelic definitely have undeniable benefits to deal with PTSD,ADDICTION,TRAUMA AND DEPRESSION ETC.The experience gave me freedom.I was Able to get shrooms,dmt,edibles,lsd etc from this licensed mycologist who ships to my location without hassel*
Psychedelics healed me. I can't explain it but my experience has been quite spiritual. Depression and anxiety entirely gone.
Be careful. It helped me too overall but you know the rumor about like people thinking they r a glad of orange juice and then never recovering. I got very close to that in 2020. I stayed away for a week 04/28/20 - 05/08/20 and I didn’t come back to reality until July 3rd. I had taken a gel tab . Just one. I puked 30min after I took it and I could tell it was gonna be a wild ride. It was. I had full psychosis.
I’m recovered now. Fully recovered I have a job. Been in a three year relationship. Found real God . (I know the spiritual aspect if very all connected which is still true it’s just that Jesus is the true God) idk anyways…
Be careful!!!
I still smoke pot.
I take lithium now too it’s a medicine.
Gimme that too
@maryrosehopkins I took 7 gels last week and 4 the week before that. I'm sorry, but unless you're predisposed to schizophrenia, you are completely and utterly full of shit.
its probably because it alters mood, specifically targeting serotonin and dopamine.
Same here. Glad others have seen the bright side of life from psychedelics :)
Keep it in mind that physiology, metabolism, brain chemistry and body size all play significant role on how one may responds.
This is actually a great review, they saved me from death bud, let’s be honest here, and mushrooms are one of the most amazing things on this planet.
Can you help me with the reliable source 🙏🏻.
I’m 60 years old and I have been suffering from depression and alcohol addiction.
Microdising helped me to get out of the pit of my worst depressive episodes, a three year long episode, enough to start working on my mental health.
I’ve tried LSD a few times with mostly positive experiences. However I had a very bad trip a few days ago. Mine lasted over 24 hours of sheer paranoia and fear, the likes of which I wouldn’t wish on my worst enemy. My body was completely numb and I felt the extreme need to want to hurt myself and others. I somehow managed to calm down by drinking herbal tea, listening to soft music and talking with a suicidal hotline.
If you ever try this drug, make sure you start with a very low dosage, have zero responsibilities and have a trip-sitter with you for at least 8 hours.
This is simple proof of why you should never take things like this.
you should not be taking anything if a drug makes you want to hurt others
@@osamedennadi6309It really isn’t
this is the main problem with LSD, one bad trip and it can fuck you up in the head quite badly, it happened to me as well and I think I still have "ghosts" of that bad trip in my personality, looking forward for healing myself this year.
Yo what does it feel like normally?
Someon on another vid jus told me Puff the Magic Draggon is about LSD.
Wow how inocent I am for a 36 year old. I still to this moment that this other person said this took that little tune to be about a magic Godzilla if you will.
Cause Puff the magic dragon lived by the see.
Hmmm sounds like Godzilla to me but of course a magic 1 as he's the macinations of a 4 year old.
This has the potential to heal so many people's trauma if only researching it wasn't so taboo and difficult.
It's only temporary. Trust me.
@@osamedennadi6309 you know this is the same stuff that people use to accidentally quit their meth addictions and stuff right lmfao "temporary"?😭
@ultragd69 It is a drug, sure it may not be as destructive as meth, but, every addict will be irresponsible and, if they don't get a good high, they'll try harder drugs
@@fruitZzed so are caffeine and sugar except those can be (and for sugar, are very) addictive unlike psychedelics lmao
@@fruitZzedThis video quite literally states lsd as non-addictive
Needs to be decriminalized so it can be created in a pharmacy and prescribed to people who need it.
for the most part all of humannity needs it atleast once
@@Opal_Elephant why ?
It gets extracted from ergot it does not get created it’s already there it’s natural and that is probably the biggest misconception about LSD
Wrong it needs to be legalized lad
Works for my ptsd and bipolar helped me soo much
Drug neuro is great! Please do more of these, they're fascinating
More to come soon...
@@neurochallenged pls tell me if i use lsd havily everi day for a month so i have very little 5-HT2A receptors, can i get them back, and does a shortige of this receptors cause long teem learning and memorizing skils (cognitive functions) pls tell me i realy wanna know
@@jakethedog5667 No you're fine, lsd is not neurotoxic at all
Amazing videos.. I m just 15 years old and your videos inspired me to learn out of textbook. I literally have a book filled with just your videos notes pls keep uploading and u r doing a great job keep it up
u good bro?
pogchamp
@@purrfect6257 no
Lmaoo felt
have you pursued any sort of formal education in neuroscience and or pharmacology since you posted this comment?
lsd really is the coolest drug ever. awesome vid =]
How dangerous it is on a scale from 0 to 10?
@@ike2938 depends on dosage and state of mind when taking the drug. Crucially though, it’s not addictive and does not have a significant physiological effect in the same way heroin/cocaine does
@@madophelia4322 what about the accessibility?
@@ike2938 well that depends on what country you live in. but it’s fairly easy buy online through the dark web/tor and get it shipped to where you live. Either that or find your local drug dealers and ask them
Where can I get some? I am a big fan of Steve Jobs and am interested in this as he was a fan.
The perceptional distortion can be one of my favorite parts of taking lsd it's so funny how a shadow cast from something can change what your seeing and idk so hard for me to put it into words
But I much prefer mushrooms over lsd
Why mushrooms over lsd? Whats the biggest difference in perceptual change?
i’d have to disagree with you here. LSD is so much better to me!
I disagree,, personally i prefer LSD over mushrooms.. to me the best description i can come up with is LSD is a cleaner trip Mushrooms are a heavy body trip and makes me nautious sometimes and i yawn alot on mushrooms and feel lethargic where LSD i am energized and alot more happy
@@danparts9333 I personally find that the comedown from LSD can be uncomfortable while mushrooms generally ease you back into sobriety. I think most of the discomfort from LSD comes from the vasoconstriction which leads to you feeling cold and clammy.
Not only isn't addictive but reduces other addictions in ny experience
Same here.. after tripping I feel free and take advantage of the cession of drug cravings
*Psychedelic definitely have undeniable benefits to deal with PTSD,ADDICTION,TRAUMA AND DEPRESSION ETC.The experience gave me freedom.I was Able to get shrooms,dmt,edibles,lsd etc from this licensed mycologist who ships to my location without hassel*
*They're on telegram as**
*@TRIPGLOOVE**
Hello I'm a person on acid rn um about 7hrs ago I had 2 brownies and a tab the rest had been kinda blankish but so many thoughts go through your brain.
Just wanna say this...
AMAZING...... but you have to be in good guidance of positive thoughts.
The rest is your immaagunatikn
See you in 12hours
Edit: listen to Top Hat - Al Bowlly
You're welcome.
Love you bro
on tabs as we speak
One of the most transformative experiences of my lifetime, forever changed my reality. LSD’s power can not be understated, the insights that can be gained are immense. It’s been nearly 25 years since the last trip, still remember it like yesterday. Experiment responsibly ☺️
if it is so transformative why didn't you use it after?
@@aleksandrzhilkin4800transformative experiences stick with you bro she wouldn’t need to keep doing it like a junkie to keep having transformative experiences a lot of people are good with just 1 experience like that and they are set
@@aleksandrzhilkin4800 I believe he didn't see a need for it. In my personal experience I've used LSD multiple times. It has helped me develop more cognitive perspectives of other people and develop more sympathy for people. I was kinda self centered back then. After those times, I felt like using the drug would be pointless.
Is it like weed at all? the comments make it to me sound kinda like THC in what happens if you get out of hand. But hmmm maybe CBD like trip if you do it right?
Then it dawns on you: “Of course, I’m LSD. I am consciousness. I am imagining myself. I am whatever I conceive myself to be because there is nothing outside my endless Mind.”
I bought some psychedelic products from a Drugstore online
Check them in Instagram.
Could you do a 2 minute neuroscience episode about piracetam?
These videos are brilliant. Thank u 🙏🏼
Generally speaking it's pretty enjoyable, but it's not until you have more difficult experiences that you begin making real progress. It's like calluses on a guitarists finger, you gotta feel the burn
i strongly recommend him he's trustworthy he ship to any location safely man he got all kinds of stuff
¿Trip_world1?
ON Instagram
Wait so like LSD doesn’t have any effect on the body? Dude that’s kickass
It has, they don’t know s#it
LSD removes things or breaks them down so you can shit them out and put new you back in the place of the removed things
Awesome! Great video
U cant explain it with words
Well the neural mechanisms you could!
Ik bro
@@jadenr1514 u really cant
It's not trying to explain how it feels it's trying to explain how it works on a neurological level to the best science understand right now. Don't be so condescending.
Nobody was being condescending tho?
Are there any negative implications of a downregulation of the 5-HTP2A receptor on one’s overall mood or baseline or anything else? I wonder this in the case of microdosers who dose small amounts every 2-3 days.
That's a good question. There has been some speculation that 5-HT2A downregulation might be linked to therapeutic effects, but it's just speculation at this point as there's not much data on it. The mechanism of microdosing (as well as the effectiveness) is still pretty unclear.
In my few years of experience I haven't had any negative experience with downregulation. In fact, after a trip the downregulation takes place in much greater fashion than with microdosing. Some suggest that receptor downregulation caused by microdosing is minimal to none. In high (trip) doses it definitely takes place and after trips most report feeling much better and their psychological condition improve drastically. After my first trip I felt great for the next few months, better than ever in my life before. I don't think it's caused by downregulation though. I think this effect is just a 'side effect', that doesn't have to do anything with the actual therapeutic psychedelic effects.
@@neurochallenged how to upregulate it
How to upregulate it
0:31 - 0:40 😼 this quote was used in a track: The Microgram - Subjective Experience
3 Hits for my first time.
1- Everything is real. Everyone is Real. Life isn’t the same.
You see things and people differently.
2- Don’t expect anything at all. Just Go for the ride. When doing any kinda of God Particles/ Hallucinating “ Drugs”. EMBRACE IT. Stop worrying, don’t think about anything. Have No noises, Background noises or perhaps music that is Not violent.
Enjoy your first time.
3- The come down sucks, the let go is horrible. But don’t let it scare you, just take your time. If you don’t have LSD
(it’s proper name) for MONTHS. Then fine. Just cope.
But personally if you really wanna delve into that, Have a sheet. Or Droplets. And then fry yourself once. (But have a friend who is semi-fried or Still capable).
Your safety is with Dosing. And Mentality
the consciousness is the observer and the universe. defining it in this way is just the universe pretending to define itself.
Can you create a content about ibogaine?
HIT UP
MACROPAUL6…..
On instagram…_^^^
His the best online drug store I know, he got DMT, LSD and more.._****
Tripped two days ago, did it a month ago on my birthday, and done it numerously several years ago, yet still wondering what a flashback is.
Bullshit law teachers tell you
i love the experience, He got magic mushroom, Lsd, Dmt, microdose, and other psych as well... My order for penis envy and chocolates bar and all kinds of weeds arrived last week
is a legit person on TELEGRAM
DON'T mix MICROSMITH1 STAY SAFE...
What is the major differences between SSRI serotonin activation compared to LSD? Why LSD can induce hallucination with serotonin receptors activation, but SSRI did not? Is SSRI cannot activated 5ht2a receptors or there is other major factors that cause these differences.
One thing is that the mechanism is different; SSRIs are inhibiting the reuptake of serotonin, not binding to serotonin receptors. But the question still remains of why the increased serotonin levels induced by SSRIs don't elicit similar effects to LSD. The answer is that no one is sure yet, but one hypothesis is that LSD prompts some change in the conformation of the serotonin receptor that influences how the receptor interacts with other cellular constituents. According to this idea, there's something unique about the structure of LSD that causes the serotonin receptor to respond differently to it than it would to the increases in endogenous serotonin levels that SSRIs would cause.
@@neurochallenged Thank you so much for the answer. Neuroscience is sooo interesting. I hope one day I can create thesis on this topic.
A key factor is also the much greater binding affinity of LSD to the receptor. LSD is preferred over serotonin itself, the natural ligand! The receptor prefers LSD, if you like.
Also, there are two different pathways activated by the receptor, the G protein pathway and beta arrestin.
Serotonin activates the g pathway more, LSD the beta arrestin.
Forgive my shocking spelling.
Awesome question though. They say the Nobel prize is in the question and not the answer, I think this is one of those questions. Now you just gotta find out the answer and collect that Nobel!
What a trippin' good explanation! ;)
Great video 👏 👏 👏
Anybody else having one of those trips where a random set of questions just led you to this video
I’m literally on cid rn and I can’t feel my legs
Me Rn Off 2 Tabs
Are there any negative interactions between lsd and amlodipine? @Neuroscientifically Challenged
Is it any hard to make it at home?
mycotripper1
On instagram
…..?¿
They have the best dmt lsd shrooms and other psychedelic edibles and ships discreetly.
I got my stuffs delivered discreetly by this mycologist whose got MDMA, chocolate bars, Isd, dmt, Mushrooms, cannabis etc
They are on Instagram or telegram
Very good video, just a small thing, LSD is considered a psychedelic which is a type of hallucinogenic drug.(Not psychedelic OR hallucinogen).
i strongly recommend him he's trustworthy he ship to any location safely man he got all kinds of stuff
ON Instagram
¿Trip_world1?
I was right, it lowers serotonin signals to a ' fraction of what serotonin normally does ', ie low intrinsic activity, inducing a dream state . . .
But that dresmstate still contains so much awareness!
Your videos are brilliant mate keep going
Okay but what does it actually do to the ion channels?
I've heard a lot of tripping stories, and they are very exciting, i would love to try magic mushrooms but I can't easily get some, Is there any realiable source I can purchase from??
I'm so interested in the experience but am terrified of having a bad trip
I tried two grams last time, it was a thrilling experience and I enjoyed it
This whole thing is pretty new to me, can I try 3grams?
@Angela carter where to search? Is it IG ??
@Angela carter alright, I'll reach out to him immediately to get some
I have a general question about making TH-cam video!! Please answer..
Can we take picture from google search and use it in our video to explain the stuff?? (With reference link on it)
Hi Safoora, you should only use images that the creator has indicated are OK for you to reuse. I use search.creativecommons.org/to search for images that I can reuse if I'm looking for an image to use in my videos (most of them I create on my own, though).
I miss LSD.
what's the best LSD trip you had?
I miss it 2 and my last trip was only a week and a half ago 😂
Truejustice420 hard to get here in the uk
mad ophelia probably my first but then again... one day I was given a red star microdot and I was already running at a thousand miles per hr on e and speed. That was a night to remember, forever!
You will love live in florida we dont miss that shit here 😆
What would happened to you if you are taking SSRI’s and have an acid trip?
Serotonin syndrome
After taking a dose of 200 ug and having a good trip, next day do anyone have intense dreams and wake up every few hours 🤔.. and I am a extrovert and love to socalize but for few weeks I feel off and nervouse and after that I am back to normal ...?
Bruh why do drugs
@@xavierthe_elfeduardo9699 bc whats the negative side effects of lsd? Did u not watch the video? Doing it safely has zero adverse health effects and its non addictive. Drugs aren't all bad bud
@@sinxsideways5900 don’t spout nonsense like “lsd has no adverse side effects”, that’s not true at all, and that’s not even what the video said. I love acid but cant stand misinformation like this.
What about the point I read about it getting trapped in the receptor causing the body to absorb it to break it down leading to why it lasts so long... Mine went 12 hours.
i strongly recommend him he's trustworthy he ship to any location safely man he got all kinds of stuff
¿Trip_world1?
ON Instagram
Can you please do a video on DMT, and trichotillomania
What is trichotillomania?
I’ve never heard of that.
@@NYBrandywineTree It's hair pulling. Just do a little research on it. It would be a lot for me to type.
@blakeedward5267 Thank you
I’m working on a DMT video right now. Look for it in a couple weeks.
@@neurochallenged That's great, I can't wait to see it.
Does lsd affect people in depression? I started smoking marijuana and decided to suicide a few months back and still im depressed and i started medications but i dont think its helping so i wanna try anything that will make me happy. I am not a bad person but my condition got so worse that i am lost so lost that every day is new and i dont remember much about past 😕💔
i strongly recommend him he's trustworthy he ship to any location safely man he got all kinds of stuff
¿Trip_world1?
ON Instagram
1:46
okay 👌🏻
How to increase memory?
Lion's mane, microdosing psychedelics, cholinergic drugs (Choline, racetams), good sleep and diet, high intensity interval training, physical exercise generally, dream journaling, mnemonic techniques (e. g. 'memory palace')
Ego dissolution and psychedelic trips.
No mention of the increase in connectivity across regions of the brain?
source / publication?
I think this is supposed be a basic explanation in a short time, so no.
@@supersaiyanzero386 ??? I meant the commenter not video author
@@userou-ig1ze plenty of articles out there. Its no joke the amount of "insight" that becomes "available". when used.
@@zzzz1192 I think I would say that if I didn't know how to read a publication. Possibly if I didn't know how to read full stop. lol
it may not have physical effect but it has mental effect which is unpredictable and varies from person to person.Don’t get fucked up and loose your sense of morality just to be cool. :)
Yea this doesn't happen unless ur wreckless with it bud. Do ur research on dosage and set and setting. Ur environment controls ur trip and ur state of mind. These drugs have also been proven to be the best treatment for depression and addiction to other substances. No one has ever gone crazy bc of LSD and no one has ever OD'd on it bc its practically impossible to do so
@@sinxsideways5900 Bro,you are good in Marketing. Lsd is a slow poison.
@@MahmudulHasan-gp9qm where is ur factual information on this. The person who synthesized it said it is one of the most least toxic substances on the planet.
@@sinxsideways5900 bro, you only believe what u want to believe.
@@MahmudulHasan-gp9qm what are u talking about. Its literally science. I can provide u with a ton of facts. Irresponsible ppl domt make a drug bad thats stupidity and that can make anything harmful. Explain how it's harmful bc u have yet to do so
I think VR could work just like LSD...
LSD needs to be legalised my god
I get my from an online store his got shroom, psychedelic and microdosing products well refined also ships to anywhere discreetly, can also guide you on anything.
His on Instagrams, with also telegrams with,,
*Mycopete%
if its effects on the brain aren't fully understood, how can it be considered generally safe? im just curious, not hating 🥳
Because even though we don't understand exactly what it does in the brain to produce its effects, we do know from animal research and about 80 years of human use that it isn't linked to life-threatening complications.
@@neurochallenged thank you for your response!
LSD is a partial agonist on 5-HT2A? I doubt this, LSD has strong affinity to it, which makes it an agonist. But LSD has partial agonism on a dopamine receptor, I think it's D3.
LSD has high binding affinity for 5-HT2A, but lower activation efficacy than other 5-HT2A ligands. I relied on a 2016 study (see reference below) for information on affinity, potency & efficacy. From that study: "LSD and psilocin were 5-HT2A receptor partial agonists, with 28% and 16% activation efficacy, respectively, whereas all of the other compounds presented higher 5-HT2A receptor activation efficacies..."
Rickli A, Moning OD, Hoener MC, Liechti ME. Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens. Eur Neuropsychopharmacol. 2016 Aug;26(8):1327-37. doi: 10.1016/j.euroneuro.2016.05.001. Epub 2016 May 20.
@@neurochallenged Thanks for the input. Very interesting
He stated this in the video tho.
Just give it to me, I'll show you what it does.
What if you inject lsd anybody have info on this?
Who else is tripping on acid rn
I want to make some and try it. Seems hard to find instructions.
Because it’s illegal lol
Bro it's one of the hardest drugs to synthieze and the precursors are really hard to get on large quantities
Awesome super
I'm on lsd.
I got my stuffs delivered discreetly by this mycologist whose got MDMA, chocolate bars, Isd, dmt, Mushrooms, cannabis etc
They are on Instagram or telegram
@Pham_smart11
When theres no one around yes of course haha
The benefits are only temporary.
Repression
It's good until it isn't, trust a 41 year old man, I promise, lol
and here i am, sad cuz of damn tolerance, :'(
I got my stuffs delivered discreetly by this mycologist whose got MDMA, chocolate bars, Isd, dmt, Mushrooms, cannabis etc
They are on Instagram or telegram
@Pham_smart11
All you did is read from an article. And you used the exact same one for lsd and magic mushrooms.
im gay
So who's gae?
What's that?
You all are deceived if you think drugs heal you
❤️🩹❤️🩹❤️🩹
*Psychedelic definitely have undeniable benefits to deal with PTSD,ADDICTION,TRAUMA AND DEPRESSION ETC.The experience gave me freedom.I was Able to get shrooms,dmt,edibles,lsd etc from this licensed mycologist who ships to my location without hassel*
*They're on telegram as**
*@TRIPGLOOVE**