I have an exam about this today and I was always confused about certain parts in this pathway. This video clearly and succinctly explains the pathway, thank you so much!
I'm glad you saved the simple explanation for the end because it helped me digest such a detailed explanation of all of the macronutrients it regulates by blocking them... I think 😅 Black seed oil 👍
1. AKT is an inhibitor of TSC1/2 2. TSC1/2 is an inhibitor if Rheb. 3. Rheb is an activator of mTORC1 AKT inhibits the inhibitor of Rheb (TSC1/2). Thereby allowing more Rheb to activate mTORC1 allowing for more activation of TSC1/2 as compared to if AKT was NOT present
Is GSK3 the same as GSK3-ß from Wnt-signaling (Activation of Akt leads to inactivation of beta-Catenin Destruction Complex, leading to a proliferative signal through a accumulation of beta-Catenin in the nucleus)? This would be an additional way how Akt stimulates cell proliferation?
Great Job! Really helpful! But in the part relation to Glycogen synthesis is little bit confusing to me. If possible please clear me! Does by GSK3 phosphorylation, GSK3 become inactive? and GS become phosphorylated or dephosphorylated?
Dear JJ Medicine, I wonder whether there is an email address I am able to contact you regarding your authorisation to use illustration elements of this material for scientific publication please? Any help is greatly appreciated. Kind regards, Olivia
Just started my research masters, this video is sweeter to my eyes and ears than any of my greatest youthful crushes.
I have an exam about this today and I was always confused about certain parts in this pathway. This video clearly and succinctly explains the pathway, thank you so much!
fantastic video on how AKT Kinase works. I learnt a lot. The author has a very lucid style of explanation. Thank you for posting.
I'm glad you saved the simple explanation for the end because it helped me digest such a detailed explanation of all of the macronutrients it regulates by blocking them... I think 😅
Black seed oil 👍
Very didactic and summarized explanation. Thank you¹
A very clearly and useful lesson, greetings from PERU
thank you for spending time and sharing your knowledge with us.
You are amazing! I wish I can be able to explain this clearly to my students just like you did. Thank you!
Super clear! Bravo!
1. AKT is an inhibitor of TSC1/2
2. TSC1/2 is an inhibitor if Rheb.
3. Rheb is an activator of mTORC1
AKT inhibits the inhibitor of Rheb (TSC1/2). Thereby allowing more Rheb to activate mTORC1 allowing for more activation of TSC1/2 as compared to if AKT was NOT present
thank you sossss much it was really useful
Great. Thank you so much
Thank you sooooo much!!
Thank you, it's pretty clear
simply perfect. i wish you could do a similar video to the pathways involved in HSP90 alpha.
Thank you so much for this lecture. It was really really helpful ☺️☺️
thx sir today my biochem exam has actually have akt pathway
Very helpfull!! thank you so much
Very good explanation.
Great video!
Thanks mate, great videos
Your videos are awesome
Keep up the good work!
Thank you
Very helpful. Thank you
Is GSK3 the same as GSK3-ß from Wnt-signaling (Activation of Akt leads to inactivation of beta-Catenin Destruction Complex, leading to a proliferative signal through a accumulation of beta-Catenin in the nucleus)? This would be an additional way how Akt stimulates cell proliferation?
Amazign work!!!
Thanks
شكراً جززززيلااااااا
Love u so much ...Thank you
Great Job! Really helpful! But in the part relation to Glycogen synthesis is little bit confusing to me. If possible please clear me! Does by GSK3 phosphorylation, GSK3 become inactive? and GS become phosphorylated or dephosphorylated?
ថឪ
Cool 😎 best ever video
10/10
nice video! What's the source of the image i can refer to?
Why both Glycogen synthesis and Glycolysis are activated?
thanku
Enjoy the content bruh
Dear JJ Medicine, I wonder whether there is an email address I am able to contact you regarding your authorisation to use illustration elements of this material for scientific publication please? Any help is greatly appreciated. Kind regards, Olivia
i’m 16. why am i here lol
Sncak vidio aktifkan dong?
In writing