'Low wavelength not activate cones', this statment is false. In the Video he corrects himself by saying the ligtht low intensity diactivates the cones. The rods have a much higher light sesitivity but the blue cones have a Adsorption Maxima at 420nm while the Rhodopsin is at 500nm. In Average while the Switching from Photopic to scotopic vision the spectral sensitivity shifts fom green to bluegreen also called Purkinje-effect/shift. So blue things appears to be brighter than red stuff.
Im a first year optom student and this was so helpful in prep for my exam! Thank you! My a level biology teacher reccomended your channel and its amazing I can still find videos here not only covering a level but university content too!
if only i found out about this channel since year 1 med school wasted 6 years now graduated and this helps review for usmle exam, thank you brilliant doc and teacher
"Oh man you know what? spiderman movie was so great! I wanna go back in again, and watch it again" 15:48 LMAOOOOOOO #Visual_adaptation Zach you are the B-E-S-T!
Thank you for another amazing video breaking down these complicated things in an understandable and organized way! Love the drawings as well - very helpful :))
Have you ever heard of the McCollough effect The McCollough effect is a phenomenon of human visual perception in which colorless gratings appear colored contingent on the orientation of the gratings. It is an aftereffect requiring a period of induction to produce it
I can't wait for the day when you have a contest for high school students and they give your whiteboard accounts accurately for scholarships. Think what kind of physicians we would have them.
I know you said that the phototransduction for rods and cones is really similar on the phototransduction cascade video, but how does the high amount of light doesn't cause the dissociation of the transducin on cones? Is that why you said the "less sensitive cones turn on"? so more sensitive cones would be turning on as adaptation to bright light occurs?
From what i know , There are about 120 million rods receptor , on each one there are plenty of escotopsin ( rhodopsin ) but these receptors have low threshold ( which means a high sensetivity to light photons ; that's why they can feel the less light in the dark after the adaptation But on the other hand, we have cones which are hugily less in number compared to rods (only 7 millions mainly exist in fovea centralis or macula lutae ) but they have a highly threshold value so they do just work on highly amounts of photons So in day light the rhodopsin is massivly destructed Which means that the rate of its destruction exceeds the rate of its synthesis in liver and retina On the other hand , theoritically only 1 million of the cones respond to the light But at the end The both cascades are the same but it only differs according to the sensetivity of the receptor ( i hope i explained it )
I have a question : From the video of photo transduction cascade, you mentioned rhodopsin getting activated by light. So if the pupils constrict in bright light to focus the light on the fovea, then how do rods "turn off"? I hope the question makes sense
This is because due to the continuous activity of light on rhodopsin it is getting continuosly broken down into all trans retinal and opsin. So not much rhodopsin is now left and that is why rods are getting turned off. Hope you understood. Please let me know
Awesome. Do you have a source you use for your knowledge? Textbook? Neuroscience book? Some books get really detailed like Guyton and Hall. Wondering where you find your information.
He uses BORON and the likes. A personal suggestion-: Try to read GANONG which is a review book of physiology and make notes. You will find some concepts explained in a breath-taking way. Though your comment is 1 year old I doubt my suggestion would be of any help or not.
sir, why does rhodopsin accumulation takes time ? as you have said that after dark to light shift rode cells become inactivate so during light I feel rod cells get enough time to prepare themselves for dark light.
Photoreceptors-
Rods-
Rhodopsin
Retinal sensitivity
Scotopic vision.
Cones-
Photospin
Visual acuity
Colour Vision.
Dark to light adaptation-
Pupil constrict
Bleaching pigment
Rods turns off
Retinal sensitivity decrease
Cones turns on
Colour Vision
5-10 minutes.
Light to dark adaptation-
Pupil dilation
Rhodopsin start accumulating
Retinal sensitivity increase
Rods turn on
Low wavelength not activate cones
20-30 minutes.
Colour blindness
Nyctalopia
Night blindnesses
Retinitis pigmentosum.
Thank you sir
👍
'Low wavelength not activate cones', this statment is false. In the Video he corrects himself by saying the ligtht low intensity diactivates the cones. The rods have a much higher light sesitivity but the blue cones have a Adsorption Maxima at 420nm while the Rhodopsin is at 500nm. In Average while the Switching from Photopic to scotopic vision the spectral sensitivity shifts fom green to bluegreen also called Purkinje-effect/shift. So blue things appears to be brighter than red stuff.
Really I’m so happy because we live in same time ♥️
This channel fell from heaven 💙💙
Now these are the type of people that are meant to do this job!! Thank you so much, taught me so much more than my university professor ❤️
You are my real Professor!!!for all of my med school.i m glad i found this channel in my first year ❤
Wish I had found you at the beginning of this semester.
What would I have done without you man ?
You're simply awesome.🙏
Wow thank you so much, this video helped me get a better idea what my professor was explaining in class. ✔✔👍
i really appericiate you making this informative video. one of if not the best one i've ever seen on this subject
Finally made sense of my notes my lecturer gave .This is awesome
I never understood why pupils constrict in bright light before this video. Thanks Zack, stay blessed and continue helping doctors around the world 😍
Im a first year optom student and this was so helpful in prep for my exam! Thank you! My a level biology teacher reccomended your channel and its amazing I can still find videos here not only covering a level but university content too!
if only i found out about this channel since year 1 med school wasted 6 years now graduated and this helps review for usmle exam, thank you brilliant doc and teacher
I have to tell you I have spent the whole day watching your videos haha, can't believe I only discovered them today
I love it. Excellent drawing and explanation. It draws all the points together that helps me understand the whole process. Very good job!
BROOOOOOOOOOOO!!!!!!!!! This video was the best video in explaining this process. Thank you sooooo much for making it!!!!!!!!!!!!!
I agree!!
U teach more than my professors do
you're actually clutch for this one
Thank you very much!!!!! It is truly amazing that you can condense all these information in this one video!
Excellent. Your grasp on the subject and teaching is just fab.
You're more than perfect 👌. Thanks for your excellent and brilliant explanation 👏
The best lectures are of ninja nerd
stay blessed ninja nerd , love you so much and you are the best .❣
15.55 the happiness I saw on your face was so touching u make me laugh and enjoy my med study tho if it's hard
I love this man
"Oh man you know what? spiderman movie was so great! I wanna go back in again, and watch it again" 15:48 LMAOOOOOOO #Visual_adaptation
Zach you are the B-E-S-T!
I love all of his Explaination.
You're the best teacher ever!
This man is amazing. Always a pleasure watching your videos !!!!!!!
This is gold. Thank you so much.
Thanks for your time to make this video great
FAVOURITE CHANNEL THANKYOU HOPE YOU LIVE A BEAUTIFUL LIFE 💜
Thank you for another amazing video breaking down these complicated things in an understandable and organized way! Love the drawings as well - very helpful :))
You are raw talent… original and good.
Thank you
You are awesome Ninja Nerd
Amazing and informative video
I have specialization exam for my PhD and I have this ticket - you saved my grade :D
thank you i am in ophthalmology residency, but no one help me to understand basic as you
Best chenell so far
Thank you so much Zach.
dude is a LIFESAVER!!!!!!
Terrific and glorious ninja
Seriously a best lecture ❤️🙏
Zack paaji tussii great ho ji .❤❤
You are truly blessed! Thank you!
Ultimate explanation sir 🔥🔥
Thank you as always for this amazing work of art !
Have you ever heard of the McCollough effect
The McCollough effect is a phenomenon of human visual perception in which colorless gratings appear colored contingent on the orientation of the gratings. It is an aftereffect requiring a period of induction to produce it
You are a gift ❤️❤️❤️
Need the video on the embroyological development of human eye
thank you soooooooo
much Zach
I can't wait for the day when you have a contest for high school students and they give your whiteboard accounts accurately for scholarships.
Think what kind of physicians we would have them.
Thank you sir such a nice clear lecture and one of my favorit lecturer love from afghanistan
Amazing!
the best teacher
Thanks sir, sir I want study about ERG, so please suggest video..
THANK YOU
Awesome video
I know you said that the phototransduction for rods and cones is really similar on the phototransduction cascade video, but how does the high amount of light doesn't cause the dissociation of the transducin on cones? Is that why you said the "less sensitive cones turn on"? so more sensitive cones would be turning on as adaptation to bright light occurs?
From what i know ,
There are about 120 million rods receptor , on each one there are plenty of escotopsin ( rhodopsin ) but these receptors have low threshold ( which means a high sensetivity to light photons ; that's why they can feel the less light in the dark after the adaptation
But on the other hand, we have cones which are hugily less in number compared to rods (only 7 millions mainly exist in fovea centralis or macula lutae ) but they have a highly threshold value so they do just work on highly amounts of photons
So in day light the rhodopsin is massivly destructed
Which means that the rate of its destruction exceeds the rate of its synthesis in liver and retina
On the other hand , theoritically only 1 million of the cones respond to the light
But at the end
The both cascades are the same but it only differs according to the sensetivity of the receptor
( i hope i explained it )
Great baby ,, I really appreciate this hard work ...,
you're a life saver
Amazing ❤ thanks a lot ! 🙌🏻🙌🏻
Can you do a segment on color blindness? And the different types?
THANK YOU SO MUCH!!! Thank youuuuuuu.
question : why does the rhodopsin have to accumulate ? in other words where did it go in the first place for it to accumulate ?
thanks in advance .
Thank you so much.
Thank you
can u provide the link of visual pathway I am unable to find it
Huge fan of ur sir😊
Wow! you are so so great! Thanks a lot!!!
Thank you sir
thank you for helping me pass the exam, sir Q_Q
Excellent
your videos are amazing! helped me understand so well thank you:)
nice explanation
Ohhh man you are genius ❤️
Thanks sir....u r the best❤️
Legend!
Really helpful
superb awesome sir
You’re unbelievable!!!
u r best , thanks sir
💛 thank you
you make everything make sense
nice lecture 👍
thank you so so so so so so so much
I have a question :
From the video of photo transduction cascade, you mentioned rhodopsin getting activated by light. So if the pupils constrict in bright light to focus the light on the fovea, then how do rods "turn off"? I hope the question makes sense
This is because due to the continuous activity of light on rhodopsin it is getting continuosly broken down into all trans retinal and opsin. So not much rhodopsin is now left and that is why rods are getting turned off. Hope you understood. Please let me know
I like before i watch.
Thanks a lot ❤️
Thanks❤
Lots of love ❣️🇮🇳
thank you!!
Thank you!!!!!
Such a great lecture mahn😍
Awesome. Do you have a source you use for your knowledge? Textbook? Neuroscience book? Some books get really detailed like Guyton and Hall. Wondering where you find your information.
He uses BORON and the likes.
A personal suggestion-: Try to read GANONG which is a review book of physiology and make notes. You will find some concepts explained in a breath-taking way. Though your comment is 1 year old I doubt my suggestion would be of any help or not.
Thanks
sir, why does rhodopsin accumulation takes time ? as you have said that after dark to light shift rode cells become inactivate so during light I feel rod cells get enough time to prepare themselves for dark light.
Thank you so much!!! 😭😭
you are the best
Great, thanks so much