Testing for Insulin Resistance For Mental Health
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- เผยแพร่เมื่อ 14 พ.ค. 2024
- Mental disorders are strongly correlated with insulin resistance. Testing yourself for insulin resistance could be a powerful tool for improving not only your metabolic health, but also symptoms of psychiatric illness. Learn what tests to ask for, how to interpret the results and why insulin resistance matters for both metabolic and mental health.
Table of Contents:
0:00 - Introduction
1:10 - Insulin Resistance
2:23 - Types of Tests
2:30 - HOMA-IR Test
3:37 - Oral Glucose Test
4:00 - Kraft Test
4:26 - Disclaimer
4:51 - At Home Test
6:14 - Conclusion
Here’s a link to a detailed educational guide on insulin resistance for further reference. www.dietdoctor.com/health/ins...
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Diagnosis Diet - www.diagnosisdiet.com/
New Study: Serious Mental Illness Improves on Ketogenic Diet -
www.psychologytoday.com/us/bl...
The Role of Ketogenic Metabolic Therapy on the Brain in Serious Mental Illness: A Review
www.ncbi.nlm.nih.gov/pmc/arti...
Chris Palmer MD - www.chrispalmermd.com/
Stanford Metabolic Psychiatry Clinic - metabolicpsychiatry.com/
What Is Metabolic Psychiatry? 5 Questions Answered by Dr. Shebani Sethi
med.stanford.edu/news/all-new...
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Checking a HOMA-IR in my psychiatric practice has been a powerful intervention to show patients when they should consider addressing their diet and lifestyle, particularly those with treatment-resistant major mental disorder
~ Low carbohydrate diet has much improved my own mental health. Amazing ... 👌
How about measuring ketones?
This is a great idea, my mood Changed so much since I reduced sugar/ simple carbs. Like feeling less depressed and getting rid of negative thoughts about myself, this thing called self critic.
However homa-ir is not always accurate when it comes to people with accurate BMI, especially people on the thinner side.
I had insulin resistance symptoms, when I take mino-inositol it helps with my symptoms. It makes your body more sensitive to insulin. Yet, my homa-ir was in healthy range, when I checked it.
Hi Dr, I have been running a keto diet in insulin resistance patients for 8 years. That is some 12,000 patients now.
I study insulin resistance and have noticed that about 40% of patients have homa ir below 1 but on a 3 point insulin Kraft test comes out massive insulin resistance. In my opinion, Homa IR is not an effective test for assessing insulin resistance
For the past year, I have observed that about 60% of patients with isnulino resistance are taking antidepressants.
The efficacy and effectiveness of my ketogenic diet has been documented by a scientific paper available on PUB MED entitled: The Effects of a Low Calorie Ketogenic Diet on Glycaemic Control Variables in Hyperinsulinemic Overweight/Obese Females.
Hello,
Would love to ask, have you had any female patients with PMDD and seen an improvement in their depression/suicidal ideation/anger/irritability when putting them on a keto diet? I assume a large amount of women with PMDD are insulin resistant.
I am so glad this comment exist. There are studies that show that people with right BMI, may have not accurate results with Homa-ir.
I am one of these people, I got symptoms of insulin resistance, when I take mino-inositol it helps with symptoms, yet my homa-ir was in healthy range. Always look at symptoms first.
What is your opinion on the Triglyceride / HDL-C ratio of 3.5 or greater being an indicator of insulin resistance?
Great explanation of HOMA-IR. Thank you!
Valuable info, to the point.. practical to do. I wil share this with my community of friends. Thank you so much Bret & Team MB :-) gr Inder from the Netherlands.
Hello DrS. I'm glad you are working on mental health and I'm sure you will do a lot of good for a lot of people. Then I hope you will move on to gerontology. As a 60F I'm fighting sarcopenia and other issues of aging. I appreciate Dr Gabrielle Lyon's point of view of the contribution of muscle to metabolic health and healthy aging, but that's just one factor. Would appreciate your attention given to healthy aging, lifespan=healthspan! :)
Thank you.
If it's waist circumference, then this should not be measured at the hips (that's hip circumference). The waist is further up, around the area of the belly button. This video here explains exactly how that is measured:
th-cam.com/video/b-BXpE0itSY/w-d-xo.html
Also, it should be waist divided by height, not the other way around.
Cheers
Mario
Yes - thank you. It’s a big difference 😊
Thank you
Using a kraft test with finger prick technology from Meterbolic with my clients. Very powerful motivator in the fight against insulin resistance
Looks like a very interesting option. I look forward to learning more about them
Is this as good as the homa ir
Much better. Rather than just a fasting measure you get a post-prandial response which we can then measure the peak of insulin and glucose at 30, 60 minutes and two hour potentially three hour mark. Much greater information gained
Thanks I’d never heard of the home test; simple, cheap and no one will know if I cheated!
It can be your secret. But don’t cheat yourself. Best wishes to you, I bet you have a great sense of humor!🙂
I requested a HOMA-IR from my doctor. She asked me what the test was for. When I explained she declared she never orders tests that she can’t read. And told me to go to my naturopath.
Good summative overview. If you have a W:H ratio of 0.47 and optimum lipid profile, is it still possible to have high visceral fat? And if so, how can you find out?
Thanks for your question. In that case, it is still possible to have elevated visceral fat, although less likely. One of the bests tests to find out is a Body Composition DEXA Scan. Hope that helps!
You forgot one other test equivalent to HOMA-IR, the Triglyceride / HDL-C ratio. A value of 3.5 or greater is associated with insulin resistance.
I think you divide your waist by your height. Dividing your height by your waist circumference will always be greater than .50.
Yes! Sorry if we misspoke. It is the waist to height ratio, so divide your waist by your height.
Thank you for your great work. One question I couldn't find an answer for, also elsewhere is, if insulin resistance can occur only on the brain level and not showing up in the HOMA-IR. If so, what marker could be used as a surrogate to get a first indication of that brain tissue insulin resistance before having to do more invasive tests? Domingo
Thanks a great question, and one we don't have a great answer for yet. But researchers are looking at this. It could be blood-brain-barrier imaging like Dr. Calkin is doing, or other similar tests. Let's see where the science goes on this!
@@metabolicmindhello,
What forums/platforms/websites can I look at often to get the latest info in regards to these happenings in this field? Other than this TH-cam channel, which is AMAZING!
TG:HDL Ratio less than 1 is another way to tell apparently
TyG index is easier than HOMA-IR with better sensitivity and specificity.
Thank you for your comment. That's a really good point about using the triglycerides/glucose index. It can be a very helpful marker as well, especially since they are standard blood tests. I appreciate you mentioning it.
@@metabolicmind I love it, and what is very fascinating is almost everyone is insulin resistance and/or has a high propensity for NAFLD. No wonder everyone is so sick!
I love the idea of a lab test to measure the existence and severity of insulin resistance but the doctors where I live don't want to go through the cost. They just rely on visual signs like abdominal fat and skin discoloration at the skin folds. It's very frustrating.
OGTT with Kraft insulin assay test
Ask your doctor for that and the answer will either be no or wtf is that. My endocrinologist won't prescribe, he says it's not necessary.
@@iss8504
Change doctor
@@bobcocampo change body
I told my Dr. about HOMA-IR, and she said, "what..?". And refused to get me any tests other than the basic panels SHE wanted.
Check out ownyourlabs.com They offer discounted labs people can self order to get what their doctor wont order.
Thank you! But clarification. I just divided my height by waist and got a score of 1.8. To get a score of 0.5 I'd need a waist of 130 inches which would make me Insulin Resistant for sure. Don't you mean to divide waist by height?
You are correct! It is the waist to height ratio, not the other way around!
What if you dont have metabolic dysfunction in the body but have bipolar? Could it be possible that insulin resistance can be just within the brain and not the whole body? Is only someone who is insulin resistant able to benefit from the ketogenic diet for mental health? Thank you for all you do by the way🙏
Thanks for your question. Ketosis can benefit brain function by improving insulin resistance and providing ketones as a fuel source. So, in theory, ketosis could still benefit people even if they don't have insulin resistance. But as you alluded to, it's possible that brain insulin resistance could exist even if it isn't detected systemically. We need better ways to detect brain insulin resistance to know if that is the case. But this is a long-winded way of saying we have more to learn from a mechanistic standpoint, but clinical practice and theory suggest that someone could benefit even without detectable insulin resistance.
@@metabolicmind thank you so much for your reply, this makes total sense. I will report back to see if it helps for us:)
What is your opinion of using the Triglycerides/Glucose Index to measure insulin resistance and NAFLD? I read an article that said that the TyG index is a better indication of insulin resistance than HOMA-IR.
I think it is a very good marker. it is hard to say for sure which is "better," but I think the more you look at, the better idea you have.
So my height is 65 inches and my waist is 30 inches. That gives me a reading of 2.2. I'm 120 lbs and you want me to lose weight???
Sorry, there was a spot where I misspoke. It is waist to height ratio, so 30/65=0.46 so based on that calculation, you're less likely to have insulin resistance.
Thanks. That's more like it.
@@metabolicmind
Why not just test your fasting insulin? Can you have low fasting insulin and high fasting glucose? If not, then a low fasting insulin is all that is needed, no need for homa ir.
Why ? Because Most Drs will not order fasting insulin unless you are diabetic and taking insulin ( Standard of Care Insurrance rules ).
But you can pay for it yourself at Quest labs out of pocket.
Dr. Scher, I appreciate all the work and dedication to helping people over come mental illness, nutritionally. And this is a good video. However, because most people are going to do the waist divided by the height test you need to correct your instructions on how to do that. I have been on a low carb diet for a number of months and I have been no to low carb high fat diet for about 2 1/2 months. I followed how to measure the waist on this clip.
th-cam.com/video/b-BXpE0itSY/w-d-xo.html
And then I divided my waist measurement of 35 inches where I took the tape measure all the way around my waist as she instructs, by my height of 5 foot 4” turned into inches. So 35 Divided by 64, which gave me a result of 0.546875
I hope I did that right and if so, then I have a ways to go to get below 0.5, but not nearly as much as I would have three or four months ago.
5:58 You mean the opposite right? Divide your waist by height.
Yes!