Got SIBO? It's a mistake to ignore SIFO! (Candida)
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- เผยแพร่เมื่อ 5 ต.ค. 2024
- People with SIBO are more susceptible to developing SIFO aka small intestinal fungal (Candida) overgrowth. Learn why this is the case, how this can affect the immune system, and what to do about it.
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Videos referenced:
How SIBO causes slow motility: • Could THIS be the caus...
How I successfully treated my hydrogen sulfide SIBO: • How I Treated My Hydro...
Playlists referenced:
Watch my SIBO playlist here!: • Hydrogen Sulfide SIBO!...
References:
1. Leite, Gabriela, et al. "The duodenal microbiome is altered in small intestinal bacterial overgrowth." PloS one 15.7 (2020): e0234906.
2. Erdogan, Askin, and Satish SC Rao. "Small intestinal fungal overgrowth." Current gastroenterology reports 17.4 (2015): 1-7.
3. Renga, Giorgia, et al. "To be or not to be a pathogen: Candida albicans and celiac disease." Frontiers in immunology 10 (2019): 2844.
4. Jacobs, C., et al. "Dysmotility and proton pump inhibitor use are independent risk factors for small intestinal bacterial and/or fungal overgrowth." Alimentary pharmacology & therapeutics 37.11 (2013): 1103-1111.
5. Noble, Suzanne M., Brittany A. Gianetti, and Jessica N. Witchley. "Candida albicans cell-type switching and functional plasticity in the mammalian host." Nature Reviews Microbiology 15.2 (2017): 96-108.
6. picture Nikou, Spyridoula-Angeliki, et al. "Candida albicans interactions with mucosal surfaces during health and disease." Pathogens 8.2 (2019): 53.
7. drruscio.com/s...
8. www.drweitz.co...
High-quality, peer-reviewed journal articles on bartonellosis:
1. Giladi, M., Maman, E., Paran, D., Bickels, J., Comaneshter, D., Avidor, B., ... & Wientroub, S. (2005). Cat‐scratch disease-associated arthropathy. Arthritis & Rheumatism, 52(11), 3611-3617.
2. Maman, E., Bickels, J., Ephros, M., Paran, D., Comaneshter, D., Metzkor-Cotter, E., ... & Giladi, M. (2007). Musculoskeletal manifestations of cat scratch disease. Clinical infectious diseases, 45(12), 1535-1540.
3. Maggi, R. G., Mozayeni, B. R., Pultorak, E. L., Hegarty, B. C., Bradley, J. M., Correa, M., & Breitschwerdt, E. B. (2012). Bartonella spp. bacteremia and rheumatic symptoms in patients from Lyme disease-endemic region. Emerging infectious diseases, 18(5), 783.
4. Mozayeni, B. R., Maggi, R. G., Bradley, J. M., & Breitschwerdt, E. B. (2018). Rheumatological presentation of Bartonella koehlerae and Bartonella henselae bacteremias: A case report. Medicine, 97(17).
5. Breitschwerdt, E. B., Maggi, R. G., Duncan, A. W., Nicholson, W. L., Hegarty, B. C., & Woods, C. W. (2007). Bartonella species in blood of immunocompetent persons with animal and arthropod contact. Emerging infectious diseases, 13(6), 938.
6. Kalogeropoulos, C., Koumpoulis, I., Mentis, A., Pappa, C., Zafeiropoulos, P., & Aspiotis, M. (2011). Bartonella and intraocular inflammation: a series of cases and review of literature. Clinical Ophthalmology (Auckland, NZ), 5, 817.
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Mast Cell Activation Resources:
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#sifo #candida #bartonellababe bartonella #bartonellosis #jakepicker
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✩ OTHER WAYS TO SUPPORT MY HARD WORK: I believe that everyone should have access to affordable, high-quality healthcare and I also believe that people should be compensated for their hard work. If you appreciate my hard work, research, and advocacy, you can also support me via PayPal and Venmo. You can find me on PayPal with my username @bartonellababe or by searching Jake Picker. My username on Venmo is Jake-Picker. No one needs to support me in this way and please do not gift me if you are not in a position to do so!
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Castor oil is an excellent antifungal.
It works better on candida than most antifungals (which are often quite toxic).
Castor oil is not toxic.
If you have a lot of castor oil it is a laxative i.e. More than 3 tablespoons a day.
1-3 tablespoons a day is the recommended amount.
If you get the laxative effect take less.
Castor oil is much cheaper than any extract of castor oil.
You'll soon know if it agrees with you... but if it's killing your candida the chances are you're going to like it because it makes you feel better.
🙂
Thank you for your research! Would love another video on SIFO treatment.
Awesome!! Putting it on the docket 🙂
@@BartonellaBabe Me too! Thanks, this was a great video, very helpful.
I would love this video if could.
This is SIBO/SIFO journey has been a living HELL. But hey, I guess I'm way further than my 15 yr old self, when the doctor shrugged his shoulders, called it IBS, and had me eat Activia every day (I'm relatively intolerant to diary....).
Doctors are too busy to involve in each personal case . Really disappointing
I've been on a meat only diet for 9 months. My severe SIFO has been gone since the first month since my Carnivore WOE.
How severe was it??? I have it so bad i have itching all day and brain fog is so bad i can barely talk. Please help
Love your work Jake. Soooo clever. And hilarious.
Thank youuuuuu Chantal. You know how to make me happy lol
Hi, Jake! I used to have very very bad Candida, and it was giving me relentless yeast infections and UTIs, after like more then 10 g of sugar eaten a day. I was treating it with fluconazole back and forth. But in 2019 I had EBV reactivation (while also having H2S LIBO) and was using whole bunch of everything to treat it. Nothing helped much, until I got that big tote of Monolaurine from Amazon. It worked really great, so in addition to bringing EBV down I also apparently killed all the yeast in my gut. The stool test didn't show any yeast whatsoever.
Also the last few days I was recearching hard about neurological symptoms of chronic infections with food intolerances like sulfur, and I started reading about CBS mutations and what came up was ammonia problem. So it turns out, that ammonia contributues to lots of symptoms of people with chronic inflammatory conditions and especially Lyme. At some point the liver and kidneys can't handle all the ammonia that's being produced by bacteria or in result of genetic enzymatic deficiencies and it causes brain fog, body pains, headaches etc. it's generally highly toxic to the body, especially to the brain that can't process it at all. Ammonia deplets BH4, and its deficiency can cause MCAS. Go figure what excactly causes MCAS in people with multiple infections though. =D
So you might want to look into it, because Candida and Lyme all contribute to high ammonia blood levels. Carnitine, Citrulline, Ornithine and Arginine help getting rid of it through urea cycle. there're other supplements too. Folks on forums suggest Yucca root, Malic acid and Resistant starch (I wouldn't do RS though, too risky for smb with a wrecked gut). Lactulose and FOS+Bifidus can help too.
The last thing I wanted to share with you: the other day I discovered a girl on YT that had Lyme for like 14 years and she had it baaad. The turning point in her healing was stem cells therapy. It's when they take stem cells from your body, and then process them in some way and inject them back. So, she went from being catastrophically ill to almost healthy. She still has food sensitivities etc., but it's a day and night difference in her condition. Her name on YT is Kimbers New Frequency, so check it out. It's really inspirational to see how people get from almost dying to living their full lives =)
Cheers! ✌️
Yes to everything you said about monolaurin and ammonia and I am SO GLAD to hear how effective the monolaurin was for you. I can't tolerate it, at least not at this time. I did try a LOLA supplement and reacted horribly to it. I don't feel like ammonia is the main factor for me. I think the SIFO is what is driving a lot of my symptoms right now and I already feel a little bit better (fingers crossed) after being on a low dose of nystatin for a few weeks and slowwwwwwwwwlyyyyyyyy titrating up
Hi, did you try manganese for ammonia?
monolaurin cured ur SIFO??
I tested negative for sibo….. but i have:
Tinea versicolor
Ringworm
Anal itching
Extreme sugar cravings…
Brain fog after food….
It has to be SIFO/candida right??
it might be, try coconut oil in that case
What sugar did you use for your breath test? SIFO sometimes doesn't like lactulose and shows negative there, but will be quite positive for glucose. You might consider trying a glucose breath test to see if that is positive.
Nope you got parasites
******Have you tested your home for mold? This can trigger SIBO / SIFO in people and mold toxicity.******
What should i eat before/during/after treatment??? any idea?
Awesome work Jake!
Thanks so much Nicole!
Great information here!!!❤
You are hilarious! made me laugh about something that is just a pain in the butt.
You go pretty deep ! Very interesting btw.
If you want a simple test for fungal infection do an OAT test: Organic Acids Test
The fungal toxins show up in the urine.
The toxins will tell you which fungal infection you have... and will pick up infections anywhere in the body.
Very useful... especially if you have more than one fungal infection and it's not just the bowel being affected.
The OAT test may also pick up other problems you didn't know you had.
🙂
What was your symptoms from sibo and Cándida
I have SIFO too. I just started my nystatin.
Hope it goes well for you!
So do I. Enough of this hell!
@@imstillhere3753 How was the Nystatin? I just started. How many days were you on and was it the Liquid?
How to take garlic or allicin if we have a sulfur sensitivity? Was taking garlic raw bt gt way too brain fogged. Is molybdenum 1st on the list before taking allicin, garlic, or NAC?
Many, if not most patients, with sulfur sensitivity cannot handle allicin. It's incredibly sulfuric. Molybdenum (Mozyme Forte) by Biotics Research has been immensely helpful for me and I can't eat without it right now. So dealing with the sulfur sensitivity is important (molybdenu, B12) and figuring out the cause(s) of that sulfur sensitivity
Thanks Jake this was interesting. This video is on par with what I’m focusing on atm. Just started monolaurin last week woooo. I would like to see a video on sifo treatment! Hope the nilstat helps you, fingers and toes crossed!
Wooooo monolaurin!!! I tried one pellet of monolaurin and couldn't do take anything for three days because of the reaction. I had a coconut issue before becoming disabled so not sure if this is why but doesn't matter because it's intolerable for me. How is it going for you?
@@BartonellaBabe that would be so horrible!! Ah ok so your body has never liked coconut bloody hell. I took 3 pellets at the start of the year and couldnt get out of bed for 3 weeks 😵💫 It bloody knocks us out hey! I’ve just started with one pellet per week (only taken it twice so far) and I’m ok so far… Just some burning / numbness and slight fatigue. Good luck with the nilstat keep us updated!
@@catashtrophe0 oh my god 3 pellets put you out for three weeks!! I believe you but I cannot believe that. That is absolutely insane and horrible. Are you taking the monolaurin for yeast or something else or for multiple things?
@@BartonellaBabe crazy!! the pellets are tiny too, what are they doing to us haha. dr wants me on it for biofilm, but personally yeast!! i keep getting yeast infections / gut issues
…where on the rectum scale are we with the bathroom humor? ;~)
I've had sifo for 2 years now. I've been on Diflucan for years at this point and I'm still horribly nauseous.
ughhh that's terrible!! I'm so sorry. What happens if you try a different anti-fungal (herbal or pharmaceutical) and/or use a biofilm med?
@@BartonellaBabe Not much. Im not sure why it's so stubborn to get rid of but I've tried all sorts of supplements and no luck. Diflucan is the only thing that helps but it doent actually get rid of it. I miss carbs and sugar! Never thought I'd be stuck on this diet for years at this point. Between mcas, candida, and gastroparesis it is a very limited diet.
@@annaWdbn Then there's clearly an underlying factor as to why Candida is overgrown. Maybe you have low commensal bacteria (have you tested this? You can with Thryve/Biomesight), maybe Candida is protecting you from Mercury (ever had amalgrams?), maybe you live in a mouldy environment. Is your diet conducive to ridding the yeast? (No sugars/wheat/processed foods/not going crazy with carbs). If you've been treating with Diflucan for 2 years I'd say for a certainty you MUST support your gut with prebiotics + probiotics. It can't just be a kill protocol. Oregano Oil/GSE made my Candida worse because it destroyed my commensal bacteria. It could also be that your yeast is bungled up in biofilm; did you ever introduce methods for that? A proper yeast protocol requires support for the lymphatic system, biofilm and hyphenation, and raising commensal bacteria (pre + probiotics, mainly diet!) You could could try supporting your gut bugs ongoing, try other (less damaging) methods for the yeast like HICA or ozone therapy, while addressing what else it is that's causing the yeast to be so stingy.
Hi, I have insane insomnia after taking Rifaximin. It has been four weeks since that but I still can't fall asleep and it feels like I had 10 cups of coffee. I have no pain just like a moving feeling all night, gas in the morning. My stools are soft before I was constipated. I can't tolerate fermented foods, and probiotics. It also gives me insomnia. I eat very plain like rice and beef. Please can you suggest what to do?
My Lyme doc recommended Ozone oil called Ozovita due to yeast, bacteria and parasites still present in my stool test. I cannot find any information really on this and was wondering if you did? Thank you for all you do!
Hmmm I have never heard of this! Sorry I couldn't be more helpful!
Hey, really great videos and information. I am in England and going through the exact same things as you in terms of MCAS and SiBO and potential SIFO. I even spoke to Dr Rao over email. It's crazy how similar your finding is as mine at same time lol.
Just wanted to ask the Nystatin you are taking is it sugar (sucrose) free? As it is counter productive if it has any sugar as that keeps the yeast thriving and alive. And Fluconazole with lactose is same thing. I've had both and it doesn't eradicate the issue.
My naturopathic doctor has said instead to treat the H2S Sibo and then directly after it is lowered I have to repopulate the gut in order to be able to break down the yeast itself and keep it at bay. Probiotics in the gut should keep the SIFO under control after. Also, if you can handle ginger then strong amount of ginger tea can be better than some prokinetics at moving the gut along.
Hopefully, we both get to the bottom of these issues and get our health back 🙏🏽
I get all my meds compounded with just salt so no sugar here! Probiotics in those with SIBO is controversial in terms of the scientific literature, doc's opinions, and patient anecdotes. Both of my GI doctors don't recommend probiotics for me at this time but I hope they work out for you! Dr. Siebecker says she has a pretty good mix of patients who respond well, not well, and no negative or positive response
@@BartonellaBabe thank you for the reply. So did your Nystatin have any sweeteners added? Like sorbitol or anything like that? I don't think I can get compounded over here but best they have is sugar free anti fungal and instead they have like sorbitol rather than an actual sugar added.
@@divdep3612 nope no sweeteners. Just nystatin and salt. That's what I do for all my meds that I can do that with. Sorbitol (an alcohol sugar) is harder to digest than regular sugar and can make SIBO worse according to Dr. Pimentel but everything has it pluses and minuses so we all just do what we gotta do!
How did you react to the Clarithromycin as a pro kinetic?
I’m really sensitive too and am curious.
interested in more on this for sure. believe it is a real issue for me
okay putting SIFO treatment video on the docket 🙂
God bless you!!!!!!!!!!!! ❤
Who's tried Nystatin in these comments? Just started!
How did it go with the Nystatin?
@@vincentvega3747 Good! I took it with my antibiotics so I wouldn't suffer a Candida yeast overgrowth. Pretty much in remission with SIBO and back to eating carbs, dairy and sugar. My stomach isn't 100% flat but I'm not sick anymore.
I just started this week with Nystatin. Did you notice a change in your stools and toungue(white coating). How long did you take Nystatin and the dosage? Thanks for answering😊@@shannonnelson7764
So Monolaurin is also a biofilm disrupter ?
I haven't checked the scientific literature to verify this but I have heard that from multiple doctors
You are such a babe! Thank u for the great videos too😊
Hi I have high yeast in my stool and abdominal pains are my only symtoms. What can I do?
So happy you made this video and didn't even know sifo was a real thing lol I've had years of antibiotics for my lyme and bart. I was just prescribed rifaximin, so how do wr get rid of sifo? Will the rifaximin make all this worse? Thanks in advance
There aren't any studies on whether rifaximin would make sibo worse but just thinking through it, if the small intestine has slow motility (like in those with anti-vinculin antibodies) then food debris is sitting int he small intestine longer than it should. This allows whatever microbes that are there to ferment the food and overgrow. If you are taking rifaximin or any other antibiotic, you are suppressing the bacteria and depending on the antibiotic, archaea as well, which could allow for the yeast to flourish. Anti-fungals manage SIFO. Then a prokinetic would maintain remission
@@BartonellaBabe rifaximin is suppressing the bacteria? i thought it killed them.
@@sassypants6005 each antibiotic has a different mechanism of action. Some are bactericidal, which means they kill the bacteria, while others are bacteriostatic, meaning that they inhibit the reproduction. Whether or not an antibiotic is bacteriostatic or bactericidal can depend on which bacteria and on the dosage. I don't know the exact properties of rifaximin regarding this issue but I am sure we could both find out on Google 🙂. Regardless of whether or not rifaximin is bactericidal or bacteriostatic, once you come off rifaximin, most SIBO patients need a prokinetic to maintain remission
@@BartonellaBabe so inhibiting the reproduction gives our digestive system time to eliminate what's left of the overgrowth? i'm not sure if i have sibo or sifo. my breath test was borderline tho i have all the symptoms of sibo
Science baby....SCIENCE.
Thank you Jake
Enjoy your take
You're the original, no fake
Kickin Sibo to the curb
Feelin so much better gonna stop the herb
Fight the fight
Win the war
hahaha this is a beautiful poem!! Or song or rap
Great content, thanks!
Thank you, as always, baffled waffle ❤️
If no candida was detected by endoscopy or stool sample, is it safe to say SIFO can be ruled out? For clarity, my daughter tested HIGH for methane (IMO) on her SIBO breath test. She's on round 3 of rifaximin (in addition to 1 round of metronidazole and 1 round of neomycin between doses) and although her methane level has been cut in half symptoms don't really seem to be getting any better. She's only 7 y/o, so alot of other treatments aren't really appropriate for her. Elemental diet might be in her future, but we'll need to wait until she's on winter break so she'll just be home for 3 weeks to really be dedicated to it.
Hmm I am not a doctor so I don't know the answer for sure but upper endoscopy can only get to the first part of the small intestine (the duodenum) and cannot reach the second (jejunum) or third (ileum) part so no I do not think that SIFO can definitely be ruled out. If her methane levels have come down, that shows that the treatment is working but has not been successful. Are they at normal levels? I would also say that the treatment regimen you have been given is not what many SIBO experts would recommend for IMO. They often give rifaximin AND neomycin at the same time for IMO. Elemental diet for a 7 year old sounds really rough. I would ask doc about rifax and neomycin at the same time and ask about a biofilm agent
@@BartonellaBabe Thanks for your reply. From what I can recall her methane levels were 80 (ppm?) initially when she was diagnosed and came down to 37 after the first round of Rifaximin. AFAIK, that is still far above what would be considered normal. Her GI specialist hesitated to give both Rifaximin and Neomycin at the same time because she was afraid it might be too much for my daughter's little system to handle, which is why she wanted to first try alternating between them. I will say that the 2 weeks she was on Neomycin alone was difficult, with lots of pain and more BM's than normal. Now that she's back on Rifaximin, she's feeling much better again. I know that her specialist had previously mentioned trying an antifungal if these antibiotics don't cure her, which to me indicates she's already got the possibility of SIFO in the back of her mind. I know you mentioned that you are currently on low dose Rifaximin and I could potentially see that being one way for us to manage her pain/discomfort in the future if we can't eradicate IMO. It's been a frustrating process and difficult trying to wrap my head around the fact that there is no one tried and true path to treating IMO and many doctors I've spoken to don't even seem to truly understand the difference between treating SIBO and IMO. The GI doc who performed her endoscopy and colonoscopy looked at me like I had 2 heads when I started talking about archaea and said, "no, it's bacteria." Ok, bud.
@@BlakeSuperior_Beats You're right. 37 methane is far above the normal cut off of 10. If she has IMO, the literature truly shows that rifaximin and neomycin is the most effective combo (in most people) and then you maintain remission with a prokinetic. If you maintain remission with just rifaximin, you could develop SIFO because you're not addressing the motility problem. If her breath test is still positive, that indicates more treatment. Of course, none of this is medical advise but it sounds like you need a SIBO/IMO specialist and not just any ole GI doc. Facebook groups are good for finding expert specialist docs. Can't believe the endoscopy doc didn't know there is archaea!!!! 🤦♀️
Hi Bart Babe: I got prescribed 500mg clarithmyin 2 x daily. I'm scared this may be too much.. also I did not get any other antibiotics prescribed. Is this okay to start with?
Hi there! I obviously can't give medical advice because I am not a doc but I can tell you what is commonly prescribed for bartonellosis patients. Clarithromycin is one of the most effective antibiotics for Bartonella in addition to rifampin and rifabutin. However, you may want to ask your doctor about not starting at a full dose. 500 2x a day right off the bat could induce a very strong Jarisch-Herxheimer-like reaction
@@BartonellaBabe Hi Bart Babe! I called my doctor to see about starting at a lower dose. Do you think 500mg in the evening for 20 days would be a good start (I know you're not a doc, just asking your personal thoughts) because he gave me 500mg twice daily for 10 days to start. Also do you know if treatment w antibiotics helps the POTS symptoms or poor sleep associated w bart?
@@BartonellaBabe Just also wondering about side effects of these antibiotics like Clair.. do you think they are concerning, like the heart warnings ect.. do you know if most people don't have issues?
Sorry, to ask so much, but what do you think is helpful for detox and herx reactions?
There is anecdotal evidence that nystatin caps work better than the tabs.
Good to know! Thank you. Mine is compounded with salt because of MCAS and I put them in a potato pill (literally just potato with the powder rolled in it) because I can't tolerate any capsule
Was Dr. Rao your doctor?
No he wasn't but Dr. Rahbar and Dr. Rezaie are so 2/3 Dr. R's lol
I have a question, bartonella cannot be transmitted from human to human right?
We have no compelling evidence, not even animal studies, that it can be passed from human to human. Bartonella need access to the blood stream so unless you're bleeding into someone's open wound, you're good. I have made several videos on transmission where I review the literature. People often say "well we don't have evidence that it can't" and while that is true, it's not a compelling argument once you read and study the literature to the extent that I have
@@BartonellaBabe so let’s say I have sex w a girl who has bartonella. Could I get it then?
@@Noti-hm2vl There have been no studies on this but using reasoning from other types of studies and from talking to Bartonella experts that actually conduct this research the answer is no. Anyone who says otherwise is talking out of their ass, frankly
@@BartonellaBabe fs ty