Xarelto is only controlled with the indirect INR (fibrinogen test + Ca + tissue factor III) and no prothrombin ratio is checked at all and rising liver values in the event of abnormalities can then appear in an emergency, which are also routinely used in toxic liver cirrhosis. I just personally don't understand where the actual specific proof of effectiveness as a specific anticoagulant substance lies. With XArelto there is no specific treatment feedback, only that Coagulation damage at best, even fibrinolysis in hypothetically triggered Sirs is masked, or is the same not exactly distinguishable In the indirect INR then. Also speaks specifically. enzyme or vitamin K. Often only the fibrinogen test is used as an indirect INR. There is often no direct INR as was previously obvious plus a defined amount of prothrombin in comparison. also no isolated quick with only chemically inactivated serum prothrombin (FII) undeactive amount of FII? for the activator factors VII, IX, X, and possibly V. to differentiate between them? These are relevant in order and effectiveness for normal coagulation So not factor X at all. I don't understand what it's supposed to do, except for SIRS it's often high?
I tried Xeralto - could not tolerate! Also several other blood thinners! All caused horrible ITCHING from head to toe! Finally realized I am intolerant to anticoagulants so I am looking into the Watchman and IVC filter! I don’t see this side effect listed but believe it should be!!! I took blood thinners for a month and the itching almost drove me mad! No more for me!!!!!
I have afib and am having a lot of stomach (gastritis) symptoms on several of the blood thinners. I researched the Watchman device and found out it contains nickel…and I am allergic to nickel which is in a lot of the cheap jewelry that causes me to get an infection. Xarelto has a very short time it is active in your system; about 12 hours. Warfarin is cheaper and lasts from 20 to 60 hours, so I am going to ask my doctor about it. Hopefully an upcoming ablation will eliminate the need for blood thinners.
I was found to have AFib in April, and have been taking xarelto , 20 mg, once a day. I feel there’s a side effect with difficulty in stool-- pool becomes dry, also, I concern it could harm kidney in long run. So, I myself reduce the dose to once every two day which I feel comfortable when pool. In general, I am healthy with normal blood pressure, and all data in blood test is normal ( only LDL a little bit higher at 130). Will 20 mg xarelto every two day ok ? Will it increase risk for stroke? My I watch shows my heart beat rate is between 67 to 135 with resting rate at 79. How long does it need to take xarelto? Some info says discontinued the medication could increase risk of stroke, if my heart beat go back to normal, and xarelto can be discontinued. How can it do that ?
What are possible symptoms of bleeding while using Xarelto? Symptoms of potentially serious bleeding can vary, but they may include: any bleeding that’s severe, lasts a long time, or won’t stop frequent nosebleeds unusual bleeding from your gums unexpected vaginal bleeding or menstrual bleeding that’s heavier than usual blood in your urine, which may be red, pink, or brown in color blood in your stool, which may be red or black in color, or look like tar vomiting blood, which may be red or pink in color, or look like coffee grounds coughing up blood that looks like coffee grounds severe headache dizziness, which could be a sign of low blood pressure that’s caused by internal bleeding joint pain pain, swelling, or bleeding at any wounds
what about grapefruit iits to be avoided it interacts negatively with blood anticoagulant otherwise ok mention of back pain is another problem with xarelto and there is more........
HI great video, I know people always talk about foods high in vitamin k that can clot the blood but do you need to worry about eating foods that are high in vitamin E that can thin the blood if you are on rivaroxaban ? Thanks.
Hi Robert, while vitamin E is known to have some "blood thinning" properties, it usually not significant for people taking anticoagulants like rivaroxaban.
Xarelto does not negatively kidney function in any way. The kidneys do eliminate Xarelto from the body. As such, the dose should be adjusted in patient's who have certain low levels of kidney function to avoid excessive exposure of the drug for the patient.
Alcohol certainly can increase bleed risk with these drugs. There is no defined quantity of drinks nor drinks/day to provide guidance. Do people consume alcohol when taking them? Yes. Is it ideal? No. In general, people should avoid or minimize alcohol intake when possible while taking these drugs.
I recently read that you should take xaralto at night, as most strokes happen in the early hours. It mentioned that it wears off so to be sure you are covered, take it at night. Any truth to this?
I'm going through it right now,and ally doctors tell me I have to take it for life. I can't sleep at night, I'm tired all day but can't sleep even though I'm tired.My hair is starting to shed and look stringy. My eyes hurt. I'm a bout one week away from switching back to aspirin and playing with death. This is no way to live, and I'm not scared to die. I'm so over this med.
@@patriciaortiz1683there is a lot of info on Google that explains why certain people need anti coagulants further than aspirin. It's usually for artery clots where the patient has had multiple in provoked instances of pulmonary embolisms or have had a heart attack or stroke due to an artery clot or clots. I've been doing a ton of reading because I want to go back on aspirin. I never felt bad like this on the aspirin, but I would forget to take it. I feel like I would rather take aspirin and risk death than live feeling like this on xeralto. It's terrible.
I had a DVT in my lower left calf and with testing discovered I had Factor V. I am now on Xarelto 10mg as a permanent low dose to prevent DVT's. Do we know what the long term effects of taking this drug is at 10 mg? Say for 10, 20, 30 + years... thanks
I'm wondering if increasing water consumption and making dietary changes and lifestyle changes would be better, (not sitting in office chair hours on end without even getting up). I'm going to be miserable not being able to take ibuprofen for arthritis.
Definitely a meal. Mostly protein and fiber in my case. I’ve been on Xarelto for 8 years, doc says it’s best with a meal anywhere between 300-500cal. I just eyeball it with a plate, take it right before my breakfast and drink plenty of water throughout the day!
Xarelto is only controlled with the indirect INR (fibrinogen test + Ca + tissue factor III) and no prothrombin ratio is checked at all and rising liver values in the event of abnormalities can then appear in an emergency, which are also routinely used in toxic liver cirrhosis. I just personally don't understand where the actual specific proof of effectiveness as a specific anticoagulant substance lies. With XArelto there is no specific treatment feedback, only that
Coagulation damage at best, even fibrinolysis in hypothetically triggered Sirs is masked, or is the same
not exactly distinguishable In the indirect INR then. Also speaks specifically. enzyme or vitamin K.
Often only the fibrinogen test is used as an indirect INR.
There is often no direct INR as was previously obvious plus a defined amount of prothrombin in comparison.
also no isolated quick with only chemically inactivated serum prothrombin (FII) undeactive amount of FII?
for the activator factors VII, IX, X, and possibly V. to differentiate between them?
These are relevant in order and effectiveness for normal coagulation
So not factor X at all. I don't understand what it's supposed to do, except for SIRS it's often high?
Good and clear information, but please drop the crappy pointless music. Most annoying.
I tried Xeralto - could not tolerate! Also several other blood thinners! All caused horrible ITCHING from head to toe! Finally realized I am intolerant to anticoagulants so I am looking into the Watchman and IVC filter! I don’t see this side effect listed but believe it should be!!! I took blood thinners for a month and the itching almost drove me mad! No more for me!!!!!
I have afib and am having a lot of stomach (gastritis) symptoms on several of the blood thinners. I researched the Watchman device and found out it contains nickel…and I am allergic to nickel which is in a lot of the cheap jewelry that causes me to get an infection. Xarelto has a very short time it is active in your system; about 12 hours. Warfarin is cheaper and lasts from 20 to 60 hours, so I am going to ask my doctor about it. Hopefully an upcoming ablation will eliminate the need for blood thinners.
I was found to have AFib in April, and have been taking xarelto , 20 mg, once a day. I feel there’s a side effect with difficulty in stool-- pool becomes dry, also, I concern it could harm kidney in long run. So, I myself reduce the dose to once every two day which I feel comfortable when pool. In general, I am healthy with normal blood pressure, and all data in blood test is normal ( only LDL a little bit higher at 130). Will 20 mg xarelto every two day ok ? Will it increase risk for stroke? My I watch shows my heart beat rate is between 67 to 135 with resting rate at 79. How long does it need to take xarelto? Some info says discontinued the medication could increase risk of stroke, if my heart beat go back to normal, and xarelto can be discontinued. How can it do that ?
What are possible symptoms of bleeding while using Xarelto?
Symptoms of potentially serious bleeding can vary, but they may include:
any bleeding that’s severe, lasts a long time, or won’t stop
frequent nosebleeds
unusual bleeding from your gums
unexpected vaginal bleeding or menstrual bleeding that’s heavier than usual
blood in your urine, which may be red, pink, or brown in color
blood in your stool, which may be red or black in color, or look like tar
vomiting blood, which may be red or pink in color, or look like coffee grounds
coughing up blood that looks like coffee grounds
severe headache
dizziness, which could be a sign of low blood pressure that’s caused by internal bleeding
joint pain
pain, swelling, or bleeding at any wounds
When I started taking Xarelto, I had big clots on my monthly period.
Excellent information and clear communication.
Thank you!
Thank you, Sean. Very helpful.
what about grapefruit iits to be avoided it interacts negatively with blood anticoagulant otherwise ok mention of back pain is another problem with xarelto and there is more........
Well explained. Much appreciated.
Thankyou brilliant video very very good. Can l have a couple of beers now and then whilst on xarelto
HI great video, I know people always talk about foods high in vitamin k that can clot the blood but do you need to worry about eating foods that are high in vitamin E that can thin the blood if you are on rivaroxaban ? Thanks.
Hi Robert, while vitamin E is known to have some "blood thinning" properties, it usually not significant for people taking anticoagulants like rivaroxaban.
May I know if Xarelto affects the kidney?
Xarelto does not negatively kidney function in any way. The kidneys do eliminate Xarelto from the body. As such, the dose should be adjusted in patient's who have certain low levels of kidney function to avoid excessive exposure of the drug for the patient.
You are a genius thank you
Is the risk of bleeding significantly increased if a moderate amount of alcohol is consumed regularly ?
Alcohol certainly can increase bleed risk with these drugs. There is no defined quantity of drinks nor drinks/day to provide guidance. Do people consume alcohol when taking them? Yes. Is it ideal? No. In general, people should avoid or minimize alcohol intake when possible while taking these drugs.
since I started taking xarelto, I feel like I have a bad sunburn---it burns. What is causing this? Oh I am also on plavix and duluxitine.
Very helpful.
I recently read that you should take xaralto at night, as most strokes happen in the early hours. It mentioned that it wears off so to be sure you are covered, take it at night. Any truth to this?
I"ve been on this for 2 months, and I hate it, innsomia, my energy is zapped, not to mention the insane cost. why wouldn't baby aspirin work?
I have that same question? Why can’t I just take baby aspirin?
I'm going through it right now,and ally doctors tell me I have to take it for life. I can't sleep at night, I'm tired all day but can't sleep even though I'm tired.My hair is starting to shed and look stringy. My eyes hurt. I'm a bout one week away from switching back to aspirin and playing with death. This is no way to live, and I'm not scared to die. I'm so over this med.
@@patriciaortiz1683there is a lot of info on Google that explains why certain people need anti coagulants further than aspirin. It's usually for artery clots where the patient has had multiple in provoked instances of pulmonary embolisms or have had a heart attack or stroke due to an artery clot or clots. I've been doing a ton of reading because I want to go back on aspirin. I never felt bad like this on the aspirin, but I would forget to take it. I feel like I would rather take aspirin and risk death than live feeling like this on xeralto. It's terrible.
Same here being on rivaroxaban for two months but it is not easy always tired, dizzy sometimes 😢
I had a DVT in my lower left calf and with testing discovered I had Factor V. I am now on Xarelto 10mg as a permanent low dose to prevent DVT's. Do we know what the long term effects of taking this drug is at 10 mg? Say for 10, 20, 30 + years... thanks
I'm wondering if increasing water consumption and making dietary changes and lifestyle changes would be better, (not sitting in office chair hours on end without even getting up). I'm going to be miserable not being able to take ibuprofen for arthritis.
"Take with Food." How much food? A full meal, or a grape?
Definitely a meal. Mostly protein and fiber in my case. I’ve been on Xarelto for 8 years, doc says it’s best with a meal anywhere between 300-500cal. I just eyeball it with a plate, take it right before my breakfast and drink plenty of water throughout the day!
Can you drink milk with xralto