Imagining CRISPR Cures | Fyodor Urnov | TEDxBerkeley

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  • เผยแพร่เมื่อ 2 มิ.ย. 2022
  • Fyodor Urnov explores the future of CRISPR and how it has the potential to save lives. Professor Fyodor Urnov is a Professor of Molecular and Cell Biology at the University of California, Berkeley, and is a Director at its Innovative Genomics Institute, leading the Center for Translational Genomics and directing the Technology & Translation division. A pioneer in the field of therapeutic genome editing, Fyodor’s research focuses on advancing genome editing technology and pushing the boundaries of how it can be applied to solve real-world biomedical problems. In his work at Sangamo Therapeutics (2000-16), Fyodor and colleagues demonstrated the first use of native gene editing in human cells and coined the term “genome editing.” Fyodor then led collaborative teams to establish at-scale applications of genome editing for human somatic cell genetics and model animal and crop reverse genetics. Fyodor was a key member of the team that developed the first-in-human clinical application of genome editing (2009), and then led a from basic discovery to clinic an approach to use gene editing to treat the hemoglobinopathies, beta-thalassemia and sickle cell disease, that has resulted in sustained clinical benefit for over 70 individuals. At the IGI, Fyodor focuses on establishing turnkey editing of the human genome for clinical use and make CRISPR-based treatments for genetic disease broadly and equitably available on-demand. He works in collaborative teams to develop first-in-human applications of experimental CRISPR-based therapeutics for sickle cell disease, genetic disorders of the immune system, radiation injury, neuroinflammation, and neurological disorders. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

ความคิดเห็น • 55

  • @bikojalal3120
    @bikojalal3120 ปีที่แล้ว +25

    I have a son he has been diagnosis with Ethylmalonic encephalopathy disease which is less than hundred people in the world they have this disease. My son is four years and eight months old he is mildly affected. Our hope is this gene therapy will be available soon and it can save our sons life.

  • @esaiqwerty
    @esaiqwerty ปีที่แล้ว +14

    Raise awareness. This is the future.

  • @robdev89
    @robdev89 7 หลายเดือนก่อน +3

    Every day my mind is blown by our Technologies and passionate people in the world, making these things possible. Thankfully the good guys do eventually find their way. 🎉

  • @maxthelionxmax9220
    @maxthelionxmax9220 ปีที่แล้ว +3

    This is excellent. No one knows who will develop a disease in the future. It’s important the solution is there before not after

  • @BearMeat4Dinner
    @BearMeat4Dinner ปีที่แล้ว +3

    Dr. Doudna ❤

  • @sanjaychoudhary8849
    @sanjaychoudhary8849 ปีที่แล้ว

    Your speak made me cry at the beigning

  • @MrDigantvora
    @MrDigantvora ปีที่แล้ว +4

    Thank you for information and bringing awareness of "Health Justice". Health justice is necessary because it, all we would be left with INFINITE GREED OF UNSUSTAINABLE HUMAN SOCIETY

  • @rickidhal3950
    @rickidhal3950 ปีที่แล้ว +2

    Thank you for championing the possibility of cure, I watched this with a ton of hope. I have to say your words are powerful but it's extremely hard to impossible to find anyone on this planet who can offer cure via crispr now. Just a bunch of videos saying we must do this. There are illnesses that can be cured now but it doesn't happen. Probably won't happen in the lifetime for many people dying right now. How do we really change this now?

    • @madhu_1489
      @madhu_1489 ปีที่แล้ว +1

      They just advertise for to get investors attention. That all nothing more!

    • @PedroDeBandit
      @PedroDeBandit 7 หลายเดือนก่อน

      We hope that someone like Jeff Bezos comes to understand that he can't take his money with him 🙏

  • @lexwil1689
    @lexwil1689 ปีที่แล้ว +1

    I am a dialysis patient and I know this would reverse the actions of kidney disease

  • @squamish4244
    @squamish4244 7 หลายเดือนก่อน

    "O for a Muse of fire, that would ascend. The brightest heaven of invention"

  • @NicoleDaly-jq4db
    @NicoleDaly-jq4db 16 วันที่ผ่านมา

    Is CRISPR being studied for use in Familial Adenomatous Polyposis patients yet?

  • @dancar2537
    @dancar2537 5 หลายเดือนก่อน +1

    we are going to automate medicine and this is going to get easy

  • @LuisOrtiz-ey1bp
    @LuisOrtiz-ey1bp ปีที่แล้ว +3

    What about for autism and global development delays/disabilities?

    • @questmarq7901
      @questmarq7901 ปีที่แล้ว +1

      Paste gene editing, look it up

  • @semrabahcivan8627
    @semrabahcivan8627 ปีที่แล้ว +2

    I have Thallasaemia heterogeneous, Hyperthyroidism, Sjogren, autoimmune diseases, kidney stones, vascular retinal occlusion. Can I get any treatment ?

  • @charlesbaha5298
    @charlesbaha5298 9 หลายเดือนก่อน

    Wouldn’t this be easy to fix NF1?

  • @akhiy5384
    @akhiy5384 ปีที่แล้ว +1

    I have PTSD and i want to erase my trauma .i don't my future children to not have any kind of disease😭

    • @lucid0443
      @lucid0443 ปีที่แล้ว +2

      i hope you’re re joking

  • @srin8116
    @srin8116 ปีที่แล้ว +1

    👍

  • @johndaly6497
    @johndaly6497 ปีที่แล้ว +1

    Need allogenic options.

  • @OneOfMany111
    @OneOfMany111 11 หลายเดือนก่อน

    👽♥️🕊️

  • @taylortischhauser4414
    @taylortischhauser4414 ปีที่แล้ว +2

    Love the idea of CRISPR in a perfect world, but this brings up concerns and raises important questions about access and equity. If gene editing becomes widely available, it could create new forms of social and economic inequality, with only the wealthy and privileged able to afford the treatments and enhancements that come with CRISPR technology.

    • @juliahello6673
      @juliahello6673 6 หลายเดือนก่อน

      He literally just talked about how to make it affordable. I swear, Americans have watched too many movies and think that movie plots occur in real life.

  • @jaqueitch
    @jaqueitch ปีที่แล้ว +1

    Indeed, Bluebird Bio is bound for bankruptcy

  • @YouTube_Enjoyerlol
    @YouTube_Enjoyerlol ปีที่แล้ว +1

    I just want to genetically engineer myself to stop aging after the age of 25 😆 👌 let’s gooooo

  • @nmbr1ctrman
    @nmbr1ctrman ปีที่แล้ว +5

    Weaponizing Crispr seems to be a big issue in the future as well

    • @religionisapoison2413
      @religionisapoison2413 ปีที่แล้ว

      Yeah like editing a SARs virus..... And making billions of dollars for you and your buddies while it spreads around the world

    • @questmarq7901
      @questmarq7901 ปีที่แล้ว +7

      This is the last of our problem. We need gene therapy asap

    • @nmbr1ctrman
      @nmbr1ctrman ปีที่แล้ว

      @@questmarq7901 won't matter if someone creates a super virus and destroys humanity.

    • @sanjaychoudhary8849
      @sanjaychoudhary8849 ปีที่แล้ว +1

      ​@@questmarq7901 so true

  • @lttrhd
    @lttrhd 8 หลายเดือนก่อน

    What about a schizophrenia?

  • @jebediahconde2143
    @jebediahconde2143 ปีที่แล้ว

    Can we crisper out the speakers mouth noises?

    • @aj-uo3uh
      @aj-uo3uh ปีที่แล้ว +1

      Can we crisper out you?

    • @jebediahconde2143
      @jebediahconde2143 ปีที่แล้ว

      @@aj-uo3uh nope. Here to stay

    • @aj-uo3uh
      @aj-uo3uh ปีที่แล้ว

      @@jebediahconde2143 Ok fine, please behave then.

    • @lttrhd
      @lttrhd 8 หลายเดือนก่อน

      The topic is too serious to concentrate on speaker noises

  • @imagreatguy1250
    @imagreatguy1250 ปีที่แล้ว

    This is the 4th comment. Shit's RARE...

  • @PedroDeBandit
    @PedroDeBandit 7 หลายเดือนก่อน

    Jeff Bezos... are you listening...

  • @documentedrecords5364
    @documentedrecords5364 ปีที่แล้ว

    Imagine.......CRISPR CURES!.....
    Me: Yeah, keep imagining idiots

    • @JZGreengo
      @JZGreengo ปีที่แล้ว

      It’s like call of duty releases, im not hyped for the next one and I’m most likely not hyped for this, im not crashing on that train like the stem cell one

  • @completelybraindead
    @completelybraindead ปีที่แล้ว +1

    This guy needs a glass of water or something. His mouth sounds dry af.

  • @Hunter_Bidens_Crackpipe
    @Hunter_Bidens_Crackpipe ปีที่แล้ว

    I can’t deal with the lip smacking. I want to watch this but it’s to much to handle

  • @yvonnecarter4118
    @yvonnecarter4118 ปีที่แล้ว +1

    Stop swallowing into the mike. It sounds dreadful and prevent me from listening 😢

    • @lttrhd
      @lttrhd 8 หลายเดือนก่อน

      Turn off sound, turn on CC