Regrowing Teeth In Old Age Is Possible! Human Trial Starts This Year
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- เผยแพร่เมื่อ 10 ก.ย. 2024
- Here we look at a new technology from Kyoto University which promises to regrow teeth. It will initially be tested on children who genetically have too few teeth but is expected to also work on regrowing teeth in the elderly.
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🌐Links in this video
Kyoto University news announcement
www.kyoto-u.ac...
Toregem Pharma web page
toregem.co.jp/...
Development of tooth regenerative medicine strategies by controlling the number of teeth using targeted molecular therapy
www.ncbi.nlm.n...
Anti-USAG-1 therapy for tooth regeneration through enhanced BMP signaling
www.science.or...
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#toothrepalcement #regenerative #tooth
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I think a Dr in 80 said that the body in a day lose 94 cells and repait this 94 cells in a day so humen can repair himself and i think how its easy just add to your body appropriate chemicals-drugs and i think humen can grovn new heart or even lost legs we need to find what chemicals-drugs
i have a question. have you tried catalase?
A lot of health scams I'm a single comment. Get off TH-cam and find a real job.
If the American medical establishment gets hold of this, it will be produced for $80 and marketed for $9,000.
We paying this for a fking implants...At least this will be a natural teeth
@@adrianbalogh6161they will probably kill this research. Too many crowns, implants, root canal industries would be destroyed 😊
That’s exactly what would it cost. Stop eating sugar and you have a chance to keep your own teeth until an early death from something else…
@@adrianbalogh6161bro if it is developed by India Or China then it is only going to be cheaper.
I've been waiting decades for this. Exciting!!!
Hi thanks. Let's hope that it is available soon!
thyeve had a processess for about a decade using pulsating red light. Out of UofT in Canada . They don't let the good stuff out .
@@cm9748 Interesting
Good luck affording it, unless you’re rich
My teeth have been waiting for this for decades. So even exciting to my mind, however connected!
My dad had a poor upbringing and by the age of 18 had lost most of his teeth. He's 83 and has maybe 5 or 4 teeth.
well he must be one charming mf then
In the meantime, I got my trusty blender!
Blinders can make Advanced Glycation End-products (AGEs)...the real reason "processed" foods are unhealthy. To reduce formation, carbohydrate should be blended alone, having either fat or protein present causes the carbohydrate to bond to fat or protein creating AGEs. Most of these healthy kidneys can remove. One they can't: glucosepane. This wedges itself into collagen, laminin, fibronectin, and elastin increasing tissue stiffness. And most relevantly, it stiffens the arteries.
There are some tricks. You can blend components separately and then mix together by hand at the end. Another thing you can do is put something acidic in there at the start. The acid helps reduce the reaction.
AGEs are more commonly known to be formed during high temperature cooking. They are also formed in the body at an increased rate when glucose is elevated, such as in diabetics.
I take some supplements to minimize these creations. I cook mostly with water, sauces and steam to avoid the temperatures that promote these reactions. I only buy and eat raw seeds and nuts, never roasted.
There is a table on the Internet that shows the AGEs levels in many foods. The methods used there I have heard undercounts AGEs in carbohydrates, but is still very useful. The very worst foods are bacon, butter, BBQ chicken, margarine, Parisian cheese, broiled hot dog, pine nuts, roasted chicken, soft cream cheese, steak pan-fried in olive oil, roasted cashews, deep-fried chicken, steak pan-fried in canola, and mayonnaise.
😂😂😂😂😂
👀😂🍉
Excellent research Richard. Thanks for your vigilance and excellent reporting.
Hi thank you! Hope that it was helpful.
Great. Teething again at 60. (I'll need a chew-toy!)
😂
Isn't that what kink is for?
God I hope this is something that consistently works, I lost my upper teeth at 21 and will be losing my bottom teeth 'soon' at 27 now, and it's been miserable
Hi thanks for sharing. It would be great if it can help you. I wish you good luck. Do you have a medical condition which is causing the problems with your teeth?
@@ModernHealthspan Yeah, I usually have trouble remembering what the name of it is, my dentist named it in passing awhile ago, but my enamel is more porous on most of my teeth, the front four bottom teeth were unaffected by the gene responsible and are pretty much pristine, while the rest are abominable, the outside of the teeth kind of crush in if something is tough or if in the time I had upper teeth I would grind them in my sleep and wake up with dust in my mouth. I imagine the bottom four front teeth similarly to tiger stripes in the way whatever the gene is called presents.
Aw bless you.
I hope they can help you or at least you get some kind of cosmetic teeth.
I have had all mine out one at a time over a few years , I can appreciate the pain and the not being confident . You are young so I hope you get teeth and they can solve the genetics too for other people.
Best of luck.
Fascinating research tho , very exciting.
This is so exciting! Thanks Richard
Hi thanks! I think so too!
Can't wait! Been following this tech for a long time. Similar to this a tech to regrow eyes is also in the works.
Gosh, I do wish this was available now. Here in the UK it is impossible to get an NHS dentist and I certainly do not have the huge cost of going private sadly. Thank you for this information.
I broke part of one upper incisive when I was child. The missing part got totally “repaired” alone in about 15 or 20 years… when I says this to dentists, they say it is impossible😅
Hi thanks for sharing and very interesting!
How did it get repaired. Do you mean the body repaired it on its own?
@@TGray-ez4vc Kind of... I suspect the tooth is simply slowly worn away with time. Such as the broken part disappeared. Just a speculation though...
Exciting, give me hope! especially not only talking, will be in human trial this year. Important and great info, thank you!
Hey Jose, thanks! Yes, it is great that they have a clinical trial planned for this year.
Really ???
Oh please let this work!
Very interesting to see this research taking place. I hope it will come to fruition with no side effects. Some of my family members would be thrilled. One always rather envies crocodiles for their capacity to regrow teeth! Thanks for the upload and do keep us posted about this, Richard!
interesting times we are in with de-aging science rapidly moving ahead.I think as soon as a cure for teeth regrowing or a cure for grey hair or something like that on the first stage comes then the investment in this science will go into billions weekly .
Hi thanks for sharing. I agree. There is a lot of promise, of therapies getting close to or into human trial. I think there will be a big bump when the first therapy that clearly fixes signs of aging becomes available in the clinic.
@@ModernHealthspan Definitely one of the first cures is about to happen which will trigger things even faster with major global finance and resources.
I always knew there were three lots , I don't know how 😊.
I keep hoping they will come through as I haven't any left.
What a wonderful bit of research 😊
What happened to human trials September started any update about human trials 🏮😁😁😁😁😁😁🏮
I cant wait for the American implant industry to go sideways. Charging 8k-12k per implant (while you can get a 5 star vacation along with full dental care overseas for 6k-includes implants and all expenses) .
Since I was a pre-teen, there have been proposed alternative ways for filling teeth or curing them of cavities (laser, electric pulse, gels), and I have never seen one of these treatments reach mainstream dentistry.
As someone who is absolutely terrified of dentistry, had just begun to trust my dentist when he left the local practice, that practice closing down, no other NHS dentists available in my town (and not likely to start up either), I face a future of going to A&E for emergency extractions or just letting old teeth fall apart and drop out.
Given the mysterious disappearance of all the other aforementioned treatments over the past 40 years, I wonder if we will really see this treatment appear in dental clinics.
And for those of us who can't afford private dentists, if this will ever be offered by the NHS (not a chance, I think). At best, I suspect it'll be exclusive for the haves, not the have nots.
This after I just spent $39,000. But I have a perfect smile, and good for another 40 years. 😅
Stop eating garbage and go carnivore
Hi Elizabeth, thanks. That sounds good. Although there is a timeline, who knows when this technology will really be available!
In India it would be not more than 4k usd
Implants? If so, was the procedure painful? Please relate your experience as I'm considering them myself.
hoping the clinical trials yield promising results and there aren’t crazy side effects. This could change the world
The best way to get it would be to be in an experimental group. When it becomes a real practice, only the rich will be able to afford it because insurance companies will never cover it.
As long as it is cheaper than an implant, which insurance also doesn't cover, it's a win. Implants cost between 3 to 5 grand each.
Awesome! Thx for sharing!
Can you guys do updates for this in future? Normally you hear a lot of headlines that go nowhere and it’s frustrating.
Oh! This is wonderful!
Is it possible to volunteer? Because I would willingly participate!!!!
i can't wait forever
Million are waiting😢😢😢
Wow, super exciting.
Thanks for sharing Richard. Do you know how to get into this trial?
Hi Ron, thanks for your question. For the trial in September there is a contact link (iact.kuhp.kyoto-u.ac.jp/patient/consultation) for further information. Note the page is in Japanese. The Phase IIa trial also has a more information link but explicitly says the trial is only for children with congenital lack of teeth and they will not respond to other enquiries. Hope this helps.
@@ModernHealthspan Thanks Richard.
I am hearing about this from 2012 and still saying 2030 it should be available ⚡ faster ASAP until 2025 and 2030 would be too late okay👍 god bless🙏 😁😁😁⭐⭐⭐🫂
Wow you really look younger! What do you attribute this to? I take donotage NMN &sirtuin 6. I'd love to know your exercise and supplement routines. Thanks!
Hi Milena, thank you! I am not sure what it would be, though I did get my hair cut. Recently I have lost a little weight, as I have concentrated on aerobic training. For exercise I am doing Zone 2, 4x4 and Sprints. I also do weights twice per week. I take quite a lot of supplements so difficult to list them all here. I take a NAD booster (currently this is Nuchido), vitamins b, c, d, k. Also Mg, Selenium, TMG, Omega-3. But not anything here that I have changed recently. I have added n1o1 serum on my face, but cannot say if it is helping yet.
I am 89 and have only a few teeth left. I am willing to be tried on if you're looking for older people?
Excellent info .... something similar I've read in one of Dr. Mercola's article. Not sbout growing actual teeth but regenerating the teeth eith cavities.
Mercola is a fraud.
Hi thanks for sharing. That sounds interesting and I guess must have a different mechanism.
now that's a news worth smiling for 😁
I remember my small hometown dentist explaining to my mom that there was not enough room for my eye teeth to come in. They were behind the existing teeth. With only novocaine and some rather effective pliars, (he may as well put his foot on my neck) my mom freaking out trying to calm me, he essentially performed oral surgery on me, awake, not having any of it, took out the existing teeth and the ones behind them. That's something you never forget. Reminds me of that movie, There Will Be Blood. 😂
One problem with awakening vestigial genes is that there is a good chance they are damaged. Every generation has around 100 mutations. If something important is damaged, then they are less likely to survive and procreate. If the gene is no longer used, it does not matter, and damage will accumulate over time. There is no selection pressure to keep it intact.
There is also a good chance these teeth will be a next size up, and not fit in the mouth. People might get some nifty canines too.
Is this medication work on that people who has lost their tooth dew to cavities or accidents ?
Can i lose all my tooth and regrow all new teeths?
Med beds shud be able to grow new teeth
I hear hydroxyapatite helps to "protect enamel" & it's now available in a couple Canadian toothpastes. I'm an old infantilized adult, so it would be just to become able to grow another round of teeth, where when needed, thanks.
Can I volunteer my teeth
I have had a full set of plastic teeth since 2008. It'd be nice to grow another set but not really necessary
This is one I'll believe when I see it.
Nice news sir I'm waiting⏳ from india
Why not front teeth? So many people are missing those and it's visible.
Beware of Calcium deficiency, also in their Bones ; Osteoporosis.. in elderly (!?!) V-B1,2,6
Growing teeth need Vitamin K3 plus Vitamin D to extract Calcium from bloodstream into Bones & growing New Tooth.(?) ...(green Veggies; Broccoli, Spinach, etc.)
Can't wait to happen soon.
That's awesome
Very cool!
Thanks!
Need my teeth
Regrowing teeth is like fusion always 20 years away, I have been reading, watching news about it for years, and for last 20 years promise was "it will be next year", and somehow, next year never comes. Not even addressing what when jaw bone has been absorbed, etc...
Scientific testing and studies usually takes about 20 years before entering human trials if all goes well. Seeing this has been spoken about and researched for 20 years is actually a good sign that the medicine and research has been going well to now be entering human trials
Great!!!! Can I also become part of an experimental group here in Germany?? This would be wonderful! 😁🥳🙏👏
Maybe it's easier to knock my grinded teeth and grow a new one than fixing the old ones 🤷♂️
What about gums to hold those teeth in place?
So science is at last progressing 😂
So how will this work if a person has severe periodontal desiese, gum, and bone loss? Does the tootg bud akso stimulate gum and bone to grow? Wont the periodontal desiese attack the new tooth as well? Or is this only for select people? There have been many of these stories for years like tooth regeneration for no more cavities, but they all seem to just fizzle away.
Pls see the video of DHS vloger he is dentist to in his video he has explained about trials of 3 stage with different conditions if got more information about this pls reply me to
@@bhakti9486 I will check that out. Im wondering how long after the trials will we know if they are a success or not. I do not believe it takes too long for a natural tooth to erupt, maybe a few months? Hopefully we will know something by Christmas or first quarter of the new year.
@@anonymousf454 hope so same for corona vaccine it was said but it worked quickly
Even in hair transplants first no one was believing but today most of the people are going for it even by bro had done it and with god grace it work completely I’m waiting for the results but this treatment should be effort able for common people pockets I personally think some treatment should be under government guidelines
When it can be possible???
How long and how much ! :/
Great if it becomes a tablet available to everyone.
i heard stories how people over 100y develop new teeth like the children have which the fall off fast and then the real new teeth grow
even if i have dental implant ?
My son’s friend, at the age of 21 or thereabouts, suddenly started growing a third set of teeth. Obviously there was not enough room for all the teeth, so he had the older ones extracted, as the new ones appeared. I know this is an extremely unusual occurrence, and I thought he was so lucky, to get brand new teeth again. We should all grow new teeth at the age of between 30 and 40, because by then, we will look after them better, perhaps, than we did before. With new insight and knowledge, we could all have all our teeth, in perfect condition, well into old age. Wouldn’t that be wonderful? No fillings, no root canals, no extractions, no crowns and bridges, no false teeth/ dentures. That would all be a thing of the past! Oh joy! 😂🤣
How The heck… Lucky guy. Do he take any medication/drug or food that might have triggered it as a side effect?
@@xDidYouKnow I don’t think he took anything that may have triggered this. He just got helluva lucky, I guess. I am so envious, to this day. 😵💫😂
@@jacksprat429 could your son ask him please? Maybe we could do the same if he took something🥹
A third set of teeth? Fascinating. Please don't regrow wisdom teeth.
Hi Scott, thanks. I was surprised to hear about the third set of teeth and it seems mostly mentioned by this team. In some of their papers they talk about the third dentition as being the cause of extra teeth growth that some people have.
Febuxostat (by prescription only), a med for gout, downregulates USAG-1
So if one gets it, then it works?
Hair regrowth would be more profitable.
For the algorithm 😎
Either you did it it already or didn't..quit pretending that it may work.
I can see it now, 60 year olds lining up at the pharmacy buying teething rings because their new teeth are coming in.
🦷 Thanks 🦷
First thing first
💙Dentistry💙
🦷💙🦷💙🦷
I need new perio too. Please hurry japan.
Always Love the Japanese 👏🏽 Doing The World a Favor For The Future 🍻
I read that it will be unaffordable for most people, and dental plans probably won’t cover it. Might as well be honest, and say that it’s just another thing for the rich and their vanity. Not for people who’s actually need it…
Where did you read it?
$275,000 a treatment im the U.S.?
Yay!
Please speak high to understand
Can it be possible for front teeths
Toothes in fronts be nice
This is great and all but will sadly not fixed the crookedness !
I hope it's not a therapy that will accidentally cause cancer 5 years down the line or something
is this click bunk?
That would be incredible 👍🤩
Hurry up. I'm not interested in paying for new teeth . It costs as much as a new car.
This will not be available tot he common man for another 20 years.
Hi thanks. I think it is not possible to judge the time scale but this is normally the way things develop.
When they figure out regrowing retina, get back to me...
We'll see when that happens.
It’s possible with transplant or injection but pills it’s so dangerous 🙀
This is possible to do yourself crazy
i don't know which one of your supplements you are taking is responsible but wow you look so much younger. Truly. Please share which you think had the most effect. It's not your skin but the way the flesh is sitting on your bone structure and no it's not because you lost weight.
Hi Billie, thank you! I am not sure. A couple of things. I got my haircut! I know you say it is not because I lost weight, but I have lost a little bit as part of some training I am doing at the moment. My supplements have not changed much recently. There are too many of them to list here, but I don't think I include anything unusual. I have started using n1o1 (a nitric oxide serum which enhances blood flow) on my face.
@@ModernHealthspan It really does look like reverse aging as opposed to a healthier looking skin. It's not cosmetic - it's incredible. Don't change a thing before you'll be signing up for high school.
2030 tak dental patients will expire
nice copium, we've had these tales since 2006
There is always talk decades before something becomes a reality. Space travel was first mentioned in 1881.
Hi thanks for your comment. This is an issue with looking at primary research, it can be a long way from the clinic. I find it encouraging that they have a schedule for the initial trials.
I read about the research starting on pigs in 1998. They are now on humans. Good luck. I might take up contact sports if I can regrow them.
@@juliahello6673and still is fairytales. The earth is flat, enclosed in a dome
"Development of tooth regereative medicine strategies by controlling the number of teeth using targeted molecular therapy" sounds like a title generated by some kind of online bullshit generator.
Will this work for people who have had root canals?
Yes but first you must remove the teeth with the root canal.
@@MysteriaNota ok, a sacrifice and pain I am willing to pay for to be able to chew gum again without worry.
Dentistes Will l'ose heir job and nerd reconversion
What is nerd reconversion?
Chances are they will grow in all directions and cause more problems than they solve.
Poor animals they tested on for 10 years
last year
this year
next year
2030
never
Next life I want to birth in Japan, cose I don't going to wait so long. Or med pod will be here before that long time... Waiting for a new world to begin as soon is possible!
Cose this one is a lie world devil's fake game! 👽🗽🤍
Thanks for sharing!