Many of the neutral compounds could still be polar molecules, such as anything with a carbonyl. Even a carboxylic acid at acidic pH will still have a polar carbonyl group. So couldn't a significant amount of these still move to the water layer? I'm sure it depends on how hydrophobic the rest of the molecule is too, but acetone and ethanol are pretty water soluble, though I'm not sure what the equilibrium would be between water and say, hexane.
Hi Dr. Laurie! I am a Pharmacy student at University of Costa Rica (UCR) and I just wanted to say that this video has been really useful for my organic chemistry laboratories. And also I have a question! Based on your explanation, I could say that a molecule like etizolam would react only with a strong acid like HCl right? And if the molecule was fentanyl that is an amide, that would react with HCl or with NaOH? I am a little confused with the acid base behavior of amides. Thank you!
Great explanation with great use of visual examples thank you
Great explanation and information is systemized. Thank you.
Many of the neutral compounds could still be polar molecules, such as anything with a carbonyl. Even a carboxylic acid at acidic pH will still have a polar carbonyl group. So couldn't a significant amount of these still move to the water layer? I'm sure it depends on how hydrophobic the rest of the molecule is too, but acetone and ethanol are pretty water soluble, though I'm not sure what the equilibrium would be between water and say, hexane.
Hi Dr. Laurie! I am a Pharmacy student at University of Costa Rica (UCR) and I just wanted to say that this video has been really useful for my organic chemistry laboratories. And also I have a question! Based on your explanation, I could say that a molecule like etizolam would react only with a strong acid like HCl right? And if the molecule was fentanyl that is an amide, that would react with HCl or with NaOH? I am a little confused with the acid base behavior of amides. Thank you!
Great video
THANK YOU