Do Gut Microbes Predict or Cause Diseases like Parkinson's? | Martha Carlin | TEDxBoulder
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- เผยแพร่เมื่อ 26 มิ.ย. 2024
- A Citizen Scientist takes a systems approach to looking at Parkinson's disease and finds the answers to PD and many chronic diseases may be in our poop.
When doctors said her husband’s Parkinson’s would eventually kill him, Martha Carlin said, No It Won’t. She stepped out of a successful career as a systems expert and into the new role of Citizen Scientist. After years of re-learning the sciences, pouring over research (and commissioning work at the University of Chicago), Martha is now a leading source of deep data on the human biome to unlock preventions and cures for many of our most complex health conditions. Her company, The BioCollective, links personal health history, metagenomics and microbiome analysis to uncover previously unknown links between chronic disease and diet, stress, and environment. She lives with her (thriving) husband John in Lone Tree, Colorado.
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at ted.com/tedx
Everyone should be so fortunate as to have a spouse as committed and loving (and smart and pragmatic) as Martha.
I met your amazing husband in a boxing class this morning. He told me all about you! I was there checking the class out for my Mother In Law. She's in the classes offered in Boulder. She was considering a move to Denver. Honestly, after meeting the class, I wish she was here already. What an amazing group of people!!! Great work! Thank you for all you're doing!
This is SO relevant! Just this week's science news proclaims that we, personally are experiencing a mass extinction. We are missing many many species of bacteria that were common to our ancestors. Regaining some of these species may mean a cure for MS, Parkinson's, ALS, Alzheimer's, diabetes and overweight, and maybe hundreds of other maladies down to the common cold.
I firmly believe that this is correct. I founded a company, The BioCollective to help accelerate the research, find answers and develop solutions. If you are interested become a member. You can purchase a kit or you can answer surveys and wait for a research project that is interested in samples from someone like you to get one for free.
6:20 "As I interviewed John and others in his Parkinson's support group I noticed similar patterns in their histories, chronic strep and other infections, repeated antibiotics, cold sores, shingles, exposures to pesticides and chemicals, diets high in sugar, and near-constant low-grade stress. The 15 year mind map of my study connected to the microbiome in almost every node." - TH-cam: Do Gut Microbes Predict or Cause Diseases like Parkinson's? Martha Carlin TEDxBoulder
I admire your dedication and love for your husband! Thank you for this important message. Praise God for giving us an INTERNAL PHARMACIST - so many people have neglected their "internal garden", the microbiome, and one of the best things you can do for your health us to start feeding your gut with Godmade foods. I have suffered with RA (Rheumatoid Arthritis), an autoimmune dusease, for 40 years and by eliminating dairy, oil and processed manmade foods I have reversed my disease and am living a wonderful new life, and I have medication-free for over two years. I would encourage everyone to return to the old paths of eating FERMENTED FOODS which are NATURALLY PROBIOTIC-RICH like homemade sauerkraut, sourdough bread, kombucha, kefir, apple cider vinegar and fermented vegetables.
this is true. doctors need to take this seriously & apply it in treating patients.
Fantastic eye-opening talk. Took by breath away.
Thank you! I appreciate that. I am trying to open people's eyes. Please share. ;-)
Going into dietetics, and I am fascinated by the gut biome. Thank you for sharing.
DAISY research eat green succinic acid
Wow....not only scientific but quite poetic Mrs. carlin -citizen scientist.......indeed... "Standing too a painting and seeing only colors" brilliant ! A wonderful. Remark ! and above all : A LOVE STORY ! Thank u from the bottom of my..........guts !
*standing too close to
*and seeing your favorite color
@@jppagano3215 Thank you so much for the kind words! Love can inspire us to do great things :-)
Extremely well done Martha!
Awesome journey by this brave, resourceful woman. And we will all benefit. Thank you. 🙏🥝🥑🥦
Thank you!
Martha you are amazing and I am glad to know you. Excellent heartfelt communication and challenge in your Tedx talk.
Parkinson's indicates unresolved rejection, massive amounts of abandonment, rejection and hope deferred. I read a book called"A more excellent way" by Henry Wright.
Yes, there is a very large emotional component to the disease. Fear is also a piece of the puzzle.
@@marthacarlin7264 So true. How does this (emotions) relate to the microbiome? And what can be done to reverse PD?
A truly awe-inspiring and moving presentation, Martha! As you know, I spent most of my career as a research microbiologist studying the effects of highly complex mixtures of heavy metals and toxic organic chemicals on microbial biodegradation pathways in complex microbial communities. See, e.g., Lewis et al. Influence of environmental changes on degradation of chiral pollutants in soils. Nature 1999, 401:898-901. Most scientists take the opposite approach, focusing on individual pollutants and selected species of microbes that could degrade or transform pollutants. The difference between the two is similar to comparing your whole-system approach versus studying specific neurotoxins present in the gut biome. It may be somewhat useful, for example, to understand the role C. botulinum and C. tetani could play in triggering neurological disorders as they produce their own characteristic neurotoxins in the human gut. But fully understanding and appreciating the wider role that gut microflora may play in neurological disorders, I suspect, is more likely to come from studying neurotoxic effects associated with shifts in the biome as a whole. Environmental researchers, for example, have discovered that certain non-neurotoxic chemicals become highly neurotoxic in the presence of certain other non-neurotoxic chemicals.
So to some extend we may specialise as a verticale approach but we need also to understand the horizontal interactions … between phenomena … ( back again to the holistic stand point of view of mind set !! )
So, what are the next steps here? Is there research being done on replacing those specific gut bacteria that are missing in order to REVERSE the disease?
yes...but there's more to it than that. Read Ruscio & Susan Blum
We are actually working on specific bacteria to help transform the ecosystem. But we also see that there are "weeds" in the garden. Its a complex ecosystem that involves rebuilding much the same as regenerative farming. Diet/food and water are critical as these determine pH, a significant factor in what grows in the "garden".
thanks ,agree with you
So what do I need to do. I'm 39 and I just got diagnosed with Parkinson I'm devastated please someone help me I wanna heal
The biggest lie you were told "It's not that simple"...... a lie we were told over and over again...The truth is that it is. The answer is within us. YOU ARE VERY CLOSE>
Hello, I am a junior at James Madison University. I'm currently in the beginning stages of a pseudo-Capstone Project in which my team is looking to develop a novel diagnostic for Parkinson's Disease. If anyone can assist me in finding some of the published research pertaining to this particular microbiome-oriented focus of Parkinson's, I would greatly appreciate it!
Curious to know the progress on this research
We will have some interesting data coming out later this year in Parkinson's. We have also identified a potential biomarker in PD stool samples that is a precusor to a previously published blood biomarker in PD and ALZ. Very likely there is a complex co-infection involved and there will be patients divided by the combination of microorganisms in the co-infection as well as their genetic risks/blood antigen type, etc.
@@mcarlinrplp, thank you for being relentless in your quest for better information than the standard medical community offers. I, too, have done and continue to do as you, just not with the same resources...yet. I have been relentless daily...daily...for a decade and regularly for a few years prior to that. I continue to seek new information daily and always will. I'm going to go ahead and assume you have already completely eliminated ALL sources of contact with gluten including skin contact for good for not only your husband but also for yourself and for as many people as you can encourage/beg to do so. It's amazing what gluten does to our FIRST brain, the digestive system, and to our second brain across that blood brain barrier. My daughter is alive today not because the standard medical community had a clue..as they still don't...but because ten years ago I figured it out on my own...with God's guidance. You are absolutely spot on regarding all you mentioned. I wish I had seen your video prior to today, and am thankful to have now seen it. I pray for you and your husband and your family. Thank you, again, for staying relentless and sharing your vital research with us all. I know without a doubt you have had an enormous amount of naysayers as have I, including from those in the standard medical community.
Laura Willingham thank you for your note. Have cut out the gluten for the most part. Rare occasions. I think that the glyphosate used is a big part of the problem. It targets a gene that is present in about 2000 species of bacteria thus reshaping the entire gut ecosystem over time with constant exposure.
@@marthacarlin7264, even the dust of gluten retoxifies the body with cascading effects that can last six months. I definitely agree the glyphosate is extremely damaging, but even without the glyphosate, wheat especially is extremely damaging and completely unnecessary, even wheat that hasn't been over hybridized and completely changed as our wheat in this nation. Prior to the changes in our grain crops, especially the wheat, people all throughout time have had issues with wheat. The process needed to consume it the best way still doesn't completely remove that possibility of damage. Repair can occur in some people, but it still occurs. Many people fair better with no grains at all. Our bodies don't have to have grains, of course, thankfully. For some, something simple like spinach causes issues. For some, nightshade produce. For some, grains. For some, legumes. For some, red meat..especially those allergic to the sugars in red meat, especially in beef. The Lone Star tick supposedly carries a contaminant that can cause that issue. You probably know all the things I've mentioned, and definitely know far more than I have learned so far. PLEASE continue to share as much as you can. I know you're obviously swamped right now with caring for your husband and continuing your research. That's far more important, obviously, but if you're sharing additional information, I would love to have access to that information and would like to know how to go about finding it. I am very thankful you've helped us learn, and are continuing your research for the benefit of us all.
Laura Willingham I am helping a non-profit put together a website for education. The early focus is on antibiotics and chemicals in the food and water. The grain connection is definitely real - it makes a “paste”. Interesting too that the wheat genome is the most complicated in the world. There was a recent story on it. I will see if I can find it again and post it. My company, The BioCollective, is looking to connect gut issues across disease classifications. We collect diet information as well so maybe we will be able to make this connection through our data to the grains.
“Are you Martha Carlin from Kentucky”? Her maiden name is the same as her married name? I’m confused. 🤔
I actually misspoke in my talk - I am the Martha Carlin from Kentucky - my maiden name was Rodgers. I was nervous and have been Martha Carlin for so long I just blooped.
@@marthacarlin7264 I'm a pharmacist working in the microbiome. If it will make you feel better, now... I have good evidence that overgrowth of bad bacteria and decline of good bacteria are actually behind Parkinson's. Carbonated water and preservatives in bread, etc are shown to be behind this. My channel has more. Wish I known of you much sooner.
#parkinson's #PD #citizenscience #microbiome #gutbacteria #poop
Great information. Side note, Martha has fabulous legs.
Thank you!
Very informative. But I just started taking some antibiotics that will really kill all my good gut bacteria. I don't have a choice really, I came down with a staph infection.
You are right. Staph infection is very serious. We have put ourselves in jeopardy from the overuse of antibiotics such that they may no longer work for some people. Hope you are on the mend.
One of the things to ask for in the future is a shot rather than a pill. Dr. Hua Helen Wang at Ohio State has shown there is a significant difference in what happens to the gut between oral and parenteral antibiotics.
@@marthacarlin7264 microbiomelabs has a spore-based probiotic called megaspore that you can take during and after that replenishes and balances your microbiome. Go to the website and Kiran Krishnan has educational videos where he explains about the microbiome and how you can repair it.
Just found this. I'm a pharmacist whose lab has made breakthrough here. My channel has more on this subject!