Pharmacokinetics: How Drugs Move Through the Body

แชร์
ฝัง
  • เผยแพร่เมื่อ 29 ม.ค. 2025

ความคิดเห็น • 104

  • @gunp0wderr0cks
    @gunp0wderr0cks 4 ปีที่แล้ว +179

    as a second year pharmacy student, I really thank you for all of your organic chemistry videos and these, keep them up

  • @beefnoodlles
    @beefnoodlles 3 ปีที่แล้ว +23

    I am watching your videos since my GSCEs; I moved to the UK when I was younger and it was really hard to study in English. But your videos made so much sense to me, that I was able to get into the uni. Now I am in my last year of Biochemistry course (bachelors) and I am still watching you! I cannot thank you enough. The impact you make is unbelievable

  • @halamikkawii
    @halamikkawii 3 ปีที่แล้ว +31

    as a second-year pharmacy student, I thank you for literally all your videos since they helped me a lot!! keep up the great work! ily

  •  4 ปีที่แล้ว +6

    Thank you for your educational content. I dropped out of school in 10th grade to pursue a life of drugs and delinquency. Im now 29, spending the last 4 years re-educating myself on subjects I never even learned. Some of this wouldnt be possible for people like me without wonderful people like yourself making this content.

    •  4 ปีที่แล้ว

      I just found out you lived in wilton,ct at one point by the way. So do i haha

  • @hannahcrandall8415
    @hannahcrandall8415 4 ปีที่แล้ว +43

    thank you for posting content like this! us nursing students appreciate it since pharm is only taught briefly but we're expected to know so much of it!

    • @sasuxsakuxfan
      @sasuxsakuxfan 3 ปีที่แล้ว +2

      so true... i'm basically teaching myself at this point

  • @ThePBandJen
    @ThePBandJen 4 ปีที่แล้ว +25

    I'm in pharmacy school. I loved your videos for my pre-req classes like organic chemistry and biology so I am thankful you did these as well! Thank you!

  • @easy461
    @easy461 4 ปีที่แล้ว +8

    I'm an Egyptian pharmacist and very interested in your lectures . You are amazing, go ahead

  • @Zetsuke4
    @Zetsuke4 4 ปีที่แล้ว +6

    im impressed by your postings of medical videos recently

  • @MsDunn-x6o
    @MsDunn-x6o 9 วันที่ผ่านมา

    I like your videos and you make them easy to understand. I am in a clinical mental health masters degree now and only had Anatomy and Physiology long time ago so your videos help. I currently have a Neuropsychopharmacology class,

  • @CarineLucilia
    @CarineLucilia 3 ปีที่แล้ว +1

    I’m in nursing and this videos are amazing!! Thank you!

  • @desislavarusekova9394
    @desislavarusekova9394 4 ปีที่แล้ว +3

    Hello from Scotland :)! I don't comment much in here but I am so glad I found your videos! You did great work with them, thank you! Easy, understandable clear, and knowledgable! I only have one recommendation (I apologize if you did it and I did not see it).Thank you! Officially I am a follower!

  • @natethedon10
    @natethedon10 2 ปีที่แล้ว

    Prof Dave! I haven't seen you in a while. You got me through undergrad, thank you 😭💜

  • @b14548
    @b14548 3 ปีที่แล้ว +3

    I absolutely LOVE this little song at the beginning!

  • @andrewliu6592
    @andrewliu6592 4 ปีที่แล้ว +7

    can you please talk about antibiotic resistance, how it is spreading, and other possible treatments that could be used for treating antibiotic resistance? (like MRSA, acinetobacter baumanii, etc.)

  • @BeaverZer0
    @BeaverZer0 4 ปีที่แล้ว +7

    Hey bud. Love your shit. Good to see ya dropping vids.

  • @li-an7700
    @li-an7700 4 ปีที่แล้ว +5

    im a filipino nursing student in the US and your video is helping me get through pharmacology

  • @getrudephiri9538
    @getrudephiri9538 ปีที่แล้ว

    Thank you for your effort in trying to make learning easy

  • @nickydaviesnsdpharms3084
    @nickydaviesnsdpharms3084 2 ปีที่แล้ว

    that's great, i didn't realise you did pharmacology too, you're an all rounder. like it

  • @tesawaluyaputri5797
    @tesawaluyaputri5797 4 ปีที่แล้ว

    Hello from Indonesia. I just found your channel. Thank you for your pharmacology videos!

  • @mohammadhmouz2563
    @mohammadhmouz2563 3 ปีที่แล้ว

    Really thank you , finally I've understood it after a long suffer , wish you all the best ❤❤❤😍😍😍

  • @nicolecurtis7016
    @nicolecurtis7016 3 ปีที่แล้ว

    Thank you for these vids! They help me a lot with me studies and exams. Thank you 🙏🏻

  • @alreadymarked
    @alreadymarked 4 ปีที่แล้ว +8

    Im wondering, what would be your next series? I hope that you'll make many videos about medicine! haha

  • @laibaali2297
    @laibaali2297 3 ปีที่แล้ว +3

    Can you please teach pharmacology topics related to MBBS? Like in a systemic way , lippincott takes a long time to interpret and understand. Your videos are very easy to understand. Thankyou so much for the videos. They are very very helpful.

  • @kenivia
    @kenivia 2 ปีที่แล้ว

    You Simplified it all, thanks!

  • @jasmincappal8730
    @jasmincappal8730 4 ปีที่แล้ว +3

    thank you for your educational content. love it ❤

  • @junaid2173
    @junaid2173 4 ปีที่แล้ว +2

    This is incredible vedio for pharmacy students

  • @favourchiazam9319
    @favourchiazam9319 2 ปีที่แล้ว

    Wow! This is beautiful 🥰
    Thank you so much sir 👏

  • @avirah__5644
    @avirah__5644 ปีที่แล้ว

    Superb video professor

  • @nneomaofo
    @nneomaofo ปีที่แล้ว

    Thanks for the good work Prof. Please are their no transcript for these videos

  • @essameliwa2251
    @essameliwa2251 4 ปีที่แล้ว +1

    Thanks a lot for your efforts

  • @colletchitiyo2799
    @colletchitiyo2799 3 ปีที่แล้ว +1

    Many thanks , this is great!!

  • @bellavita5308
    @bellavita5308 3 ปีที่แล้ว +1

    Thank you professor Dave.
    Great explanation

  • @hoseakiruii
    @hoseakiruii 3 ปีที่แล้ว +1

    Hi Prof. You're doing an amazing job!

  • @kunenethandie220
    @kunenethandie220 3 ปีที่แล้ว

    Nice summary prof

  • @sabazargarzadeh
    @sabazargarzadeh 3 ปีที่แล้ว

    Thank you so much for your videos, they are really helpful 🙏🏽❤️

  • @sumanamaity3105
    @sumanamaity3105 3 ปีที่แล้ว

    You are an amazing teacher ❤️

  • @shahabbaloch8338
    @shahabbaloch8338 4 ปีที่แล้ว +6

    professor thanks for ur videos we cant get out of homes because of lockdown i hope ur videos suffice.
    but please teach us other branches of chemistry like nuclear chemistry and analytical chemistry

  • @dlinmu
    @dlinmu 7 หลายเดือนก่อน

    Professor Dave, could you please make a video explaining how enterohepatic recycling of drugs work?? Please and thank you!!

  • @tulmajok3562
    @tulmajok3562 3 ปีที่แล้ว

    Second-year pharmacy student...
    Nice video sir

  • @kevinmoore2501
    @kevinmoore2501 4 ปีที่แล้ว +8

    I’m super interested in this stuff. I liked this vid, and added it to my faves. 👍

  • @mustaffmaxamed5439
    @mustaffmaxamed5439 4 ปีที่แล้ว +3

    Thanks

  • @jonathanbailey8376
    @jonathanbailey8376 4 ปีที่แล้ว +1

    Good videos dave!!!!!!

  • @ravena.carvalho
    @ravena.carvalho 3 ปีที่แล้ว

    Thank you very much for your explanations!

  • @GhYaAan
    @GhYaAan 3 ปีที่แล้ว

    Thank you sir better than my md teacher ❤️Love you

  • @jowiolfers6812
    @jowiolfers6812 4 ปีที่แล้ว +3

    I study biomedical sciences and your video's are very informative, clear and easy to follow!! amazing!

  • @ruhidyusifov5106
    @ruhidyusifov5106 3 ปีที่แล้ว

    Thank you for great video context

  • @WhdibAoqj
    @WhdibAoqj ปีที่แล้ว

    Thank you professor

  • @arshisiddiqui7657
    @arshisiddiqui7657 3 ปีที่แล้ว

    Thanks a lot sir😊...its helpfull👍

  • @Jslav-jj2xq
    @Jslav-jj2xq 3 ปีที่แล้ว

    Pretty good overview. 1 comment, bioavailability is the Rate and extent of absorption, not just extent. Generic drugs must demonstrate identical rates and extent of absorption for approval.

  • @abdulkarimturay5667
    @abdulkarimturay5667 2 ปีที่แล้ว

    You're indeed a professor Sir

  • @parasiftikhar159
    @parasiftikhar159 11 หลายเดือนก่อน

    Thank you!

  • @Animatedinsights9
    @Animatedinsights9 ปีที่แล้ว

    Sir you are really amazing 😍

  • @sachinmasan8574
    @sachinmasan8574 2 ปีที่แล้ว

    So easy explain ❤

  • @afifahatikasari3337
    @afifahatikasari3337 3 ปีที่แล้ว

    that so helpful sir thanks u so much!

  • @fartuunxuseenxasan4662
    @fartuunxuseenxasan4662 4 ปีที่แล้ว +3

    Thank you for your help me

  • @sabrango
    @sabrango 4 ปีที่แล้ว +3

    thx!

  • @chirazcharzou8610
    @chirazcharzou8610 4 ปีที่แล้ว

    Could u please make videos about medicine chemistry * therapeutic chemistry* I'll appreciate that so much, 🙏💓 and thank u so much for all those videos 🙏💕

  • @3la7e
    @3la7e 2 ปีที่แล้ว

    Thank u Dr ♥️

  • @Zetsuke4
    @Zetsuke4 4 ปีที่แล้ว +3

    this is good

  • @bravonline3052
    @bravonline3052 2 ปีที่แล้ว

    When exactly the metabolism occurs?is it after the drug acted on the organ or before it?

  • @dindafaara
    @dindafaara 11 หลายเดือนก่อน

    THANK YOU SO MUCHH

  • @abdallaabdelrahim8949
    @abdallaabdelrahim8949 3 ปีที่แล้ว

    does the drug metabolize in the liver and kidney before entering the bloodstream? or enter the circulation then reach the target tissue then end up in the liver & kidney

    • @hamadafd9730
      @hamadafd9730 3 ปีที่แล้ว

      If you give the drug orally it will enter the portal circulation before it reach blood stream so it will undergo metabolism so the amount of drug reach the blood stream less than same drug if you give it intravenously and the kidney has no thing with metabolism it is responsible for elimination of the drug I hope you understand me

  • @alfiethelabrador9692
    @alfiethelabrador9692 3 ปีที่แล้ว

    You summarised a 2 hour lecture in 8 minutes.... come work at my uni please 😆

  • @richricogranada9647
    @richricogranada9647 3 ปีที่แล้ว

    The way drugs reach their destination is fascinating

  • @anirbandutta3273
    @anirbandutta3273 3 ปีที่แล้ว

    I just understood the entire pharmacokinetic ( portal circulation) in my final year 😅😅 dont know why i didnt find this one b4

  • @techgautam422
    @techgautam422 3 ปีที่แล้ว

    To some extent it cleared but couldn't completely clear my doubt. My question is, if liver detoxifies any toxin in blood does it see drug as toxin? If so, how drugs work in our body if liver detoxifies it?

  • @arlix6845
    @arlix6845 3 ปีที่แล้ว

    i have a question do drugs (medication) activate the immune system if so the body will attack the drug and there will be memory cells then the next time the drug is being adminstered the bioavailablity will decrease right cause so of it will be destroyed ???

  • @Code3chef
    @Code3chef 3 ปีที่แล้ว

    Hello! Any chance I could contact you and discuss a skin absorption problem

  • @nicc8230
    @nicc8230 2 ปีที่แล้ว

    Awesooome!

  • @jpgnt5721
    @jpgnt5721 3 ปีที่แล้ว

    Thnq so much

  • @georgiarooks5472
    @georgiarooks5472 หลายเดือนก่อน

    What about drugs that is injecting in the body that lasts for 30 days invegus. Is this drug harmful to the liver

  • @riveraraissajoyce9131
    @riveraraissajoyce9131 4 ปีที่แล้ว

    hello, where did you get those photos from the slides?

  • @kondwanibanda7819
    @kondwanibanda7819 10 หลายเดือนก่อน

    Thumbs up for the intro 😂😂❤

  • @beautyofislam9688
    @beautyofislam9688 4 ปีที่แล้ว

    fantastic

  • @jakubd3426
    @jakubd3426 2 ปีที่แล้ว

    New here. Replayed intro like 100 times now xDDDD

  • @dgmickley
    @dgmickley 3 ปีที่แล้ว

    Do the kidneys help keep metals and carcinogens from the brain when you get a vaccination?

  • @dariustaylor6983
    @dariustaylor6983 3 ปีที่แล้ว

    0:20

  • @michaelberman3648
    @michaelberman3648 3 ปีที่แล้ว +1

    With all due respect, I do not agree with this definition of "bioavailability". The way I actually define "bioavailability" is the fraction of drug which reaches its targeted receptors and the active site of enzymes whether the enzymes are located on the cell membrane's surface or inside those targeted cells. When a drug reaches systemic circulation, not all of the drug will clearly reach the target receptors or enzymes at those targeted cells because the drug may bind to some extent to proteins or fatty acids within the systemic circulation of the blood and some of it will not be released by those binding proteins or fatty acids within the blood stream. And if these enzymes are in those targeted cells, then it will depend on the polarity and size of the drug molecule whether it can pass through those cellular membranes or not. Thus, based upon my definition of "bioavailability", the fraction of drug becoming truly "bioavailable" should be even lower than the more popular definition which states "the fraction of drug which reaches systemic circulation"!

    • @joefarrow1599
      @joefarrow1599 10 หลายเดือนก่อน

      Serum concentration is easy to measure by a blood test. If I use your definition, how would I measure this quantity?

  • @akosuaanointed6561
    @akosuaanointed6561 4 หลายเดือนก่อน

    Please i want to no from the beginning of pharmacology

  • @erikjohansson1814
    @erikjohansson1814 4 ปีที่แล้ว +2

    You are good and pleasant to listen to.
    Subscribed.
    Oh, love your funny bashing of the flat earth idiots.

  • @janinemaemacaraig4889
    @janinemaemacaraig4889 3 ปีที่แล้ว

    What about liberation? I thought it is LADME

  • @queenzelika8269
    @queenzelika8269 ปีที่แล้ว

    Woooow very fruitful 💉💊👍

  • @mujib4466
    @mujib4466 2 ปีที่แล้ว

    🙏🏽

  • @anasalabd6515
    @anasalabd6515 4 ปีที่แล้ว

    Adsorption not absorption

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  4 ปีที่แล้ว +7

      They are two different words with different meanings. I used the correct one.

  • @reneferdinandfilip2202
    @reneferdinandfilip2202 4 ปีที่แล้ว

    you forgot about liberation

  • @ascharyabalaji5888
    @ascharyabalaji5888 4 ปีที่แล้ว +1

    OMG he got a haircut whatttt

  • @akshaygullapalli6500
    @akshaygullapalli6500 4 ปีที่แล้ว +2

    Sir where are your hair

  • @glydeldetubio336
    @glydeldetubio336 3 ปีที่แล้ว

    I have watched a lot of your videos but this is my first time seeing you with a short hair you look so hot hahaha by the way thank you very much, you really a big help for my board exam review. Hope I will pass!!

  • @CabdifataaxCardio
    @CabdifataaxCardio 4 ปีที่แล้ว +2

    May Allah guides u to the light of Islam from the dark of non Islamic beliefs

  • @mari_6163
    @mari_6163 3 ปีที่แล้ว

    Please translation to Arabic

  • @mirad7014
    @mirad7014 3 ปีที่แล้ว

    First year medical student cries over there in the corner

  • @Mrgowds009
    @Mrgowds009 2 ปีที่แล้ว

    How drugs ex., paracetamol know that they have to move to targets
    Hoe do they know

  • @midend
    @midend 4 ปีที่แล้ว +3

    nice

  • @LashZhvania-Movies-MMA-Science
    @LashZhvania-Movies-MMA-Science 2 ปีที่แล้ว

    intro is very ennoying

  • @natethedon10
    @natethedon10 2 ปีที่แล้ว +1

    Prof Dave! I haven't seen you in a while. You got me through undergrad, thank you 😭💜

  • @quenniepacaldo4714
    @quenniepacaldo4714 4 หลายเดือนก่อน

    Amazing!!! Thank you!