Professor Sapolsky, I am a loyal listener of yours and I just want to say that this series of yours is not only very educational but also extremely cute and lovely, I get up every morning and listen to an episode that puts me in a good mood and motivates me to learn new things for the day, thank you! Happy anniversary! ❤
I recently quit drinking. The transformation I underwent was startling. In barely over a month, I lost 20 lbs, now I can run for miles, effortlessly, I feel incredible, and every aspect of my life has improved dramatically. Before I quit drinking, I did the math and discovered that I was drinking 1500 calories of beer a day. Luckily, I had only started drinking fairly recently, only drinking heavily for less than 10 years. I'm 48, now.
You had me at Winston Churchill’s ass! Then I was in awe to hear you spread the word about alcohol’s connection to cancer (I’m an RN turned Oncology Data Specialist and I collect this info for research) and we ended with pure delight hearing the Siberian Fox domestication story (I watched a documentary about this years ago)! THANK YOU Dr. Sapolsky and your wonderful offspring! Congratulations on 35 years with your mate! 🥳💖🫶🏼 sending love to this whole community!
I saw a recent video on Startalk interviewing David Speigal, also of Stanford, talking about hypnosis. I would be interested in your thoughts about how it can be used to control or modify parts of the brain. Specifically related to depression and anxiety. Happy Anniversary as well! My wife and I will celebrate our 33rd in May.
When I got home from Vietnam I didn't realize I was suffering from PTSD. The heavy drinking and assorted drugs seemed to help. I also did a lot of heavy thinking and it occurred to me one day that cause and effect could be traced backwards to the beginning of time as we know it. When I came across your absence of free will presentations a couple years ago I was and am very impressed. Keep up the good work! ~ : )
Buon anniversario and let me tell you that every Thursday for me is much more better knowing that there's a new episode. Thank you professor and thank you offspring.
What a fascinating family you all are! Your TH-cam channel is even more informative than my local community college. Thank you for welcoming us into your home! Happy Anniversary! 🎉
Delightful! Thank you once again for an interesting episode. Congratulations to Professor Sapolsky and his wife on their wedding anniversary. I think that I will watch one of the lecture series yet again... every time I watch them, I find something that I missed before.
It seems the northern elephant seal has the highest male/female lifespan discrepancy of all mammals. 50%! Wow! Happy anniversary Doc. Thanks for the video.
I've been a huge fan since I read Behave 5 years ago and have watched every episode. All are fascinating. But this one seemed especially so. I listened with rapt attention. It is so interesting to learn about the switch from rich people obesity to poor people obesity. So sorry about your data request being denied. Gosh darn lawyers anyway. I had not heard about the surgeon general's pronouncement that alcohol is a carcinogen. I quit drinking 3 years ago at 66. I wish I'd never started. And the effects of breeding foxes for domestication having the surprising effect on their appearance. Fascinating! These videos always lift my mood, which is a miracle in today's political environment. Thank you both so much!
great episode, other than the alcohol section, I laughed all the way through, and I hope you find that whistleblower, the world deserves to know about Churchill's ass. ;)
Is that the little girl that was helping Professor Sapolsky get baboon vitals in that old clip!? Wow! All grown up and still fascinated with papas work. Love to see it! ❤️ Its so wholesome
Thanks a lot sir for this new scientific podcast. As a Romania who transitioned the horrible period from a centralized economy to the free market one after the collapse of communism in the Eastern Europe I confirm your analysis on why so many males lived less than women. I knew a lot of my own friends , I'm 66, that did not make it through that period of massive job losses and lack of any hope and mostly of an uncertain future. Alcohol was the main killer of my friends and acquaintances.
I made a quick search for that gene in foxes, GTF 2I (general transcription factor, initiator). Robert mentioned it before in dog episode ☝. There is a strong connection between dog hypersociality and modification in that gene (compared to wolves who have it intact). As well in humans GTF 2I possibly makes for hypersociality, when one gene copy is lost with chromosom 7 aberration (elven syndrome). I found one fox study only, they do not conform differences in GTF 2I in domesticated and wild foxes. Yet samples are exploratory, genomes of 5-10 animals 💁♂
Your work has explored the intricate interplay of biology, environment, and behavior, often breaking down deterministic views of human nature. But what if consciousness itself is not confined to individual brains? What if thought can be shared, accessed, or transmitted beyond the structures we currently understand?
I am so excited about the picture on Mr. Sapolsky's shirt: is that really a Canis lupus?! Could you please say a word about the phenomenon of people's fear of wolves and their ecological role? How has the wolf shaped people socially historically? What is the connection between wolves and dog breeds today? Btw: Thx for the great episodes!!
I would not say legal liability is a terrible idea, if some evil corporation is poisoning your drinking water, you'll probably want them held accountable. As with anything it just depends how it's applied. With personal data, it can be de-identified for research, which I'm surprised wasn't Robert's next question on that phone call.
@PinataOblongata I think you extrapolated on the point way beyond its intention. Obviously, any society that is expected to function requires rules. Ugh....
10:59 Ah, it’s quite the revelation, isn’t it? Knowing that even Dr. Sapolsky, with all his brilliance, feels a tad... primitive when graced by the refined tones of a proper British accent. It’s rather comforting, really-like realizing even the great minds can be titillated by the Queen’s English! Lol what's it ?
So much great content! I love this series and your books. And Happy Anniversary!! I have a question - I’m interested to learn how exercise affects brain function and mental health, and also how it affects the health of other organs in the body? We often hear about how the brain communicates with our muscles. But we don’t hear about how our muscles communicate with the brain and other organs. When we do strenuous work or exercise, what are our muscles doing that produce such benefits for the rest of our body? Lastly, I’ve read there are benefits at the cellular level related to mitochondria and gene replication. What is that all about? Thank you!
Dear professor, as a depressed conflicted animal in a foreign land who doesn't know the people language, doesn't want to partake in default society groups but seeks to find their own people in comedy clubs and chess clubs or even neurology, language clubs. What do you suggest to do to survive and thrive? An individual can live their life without sacrificing their freedom of rights? How to practice social interaction without getting harmed or being harmed? Thank you for being awesome as ever.
Thanks, Sapolsky clan, I’m a fan, a reader of your books , Mr. Quibble: “Junk food” and nutrition and obesity: I’m inclined to link the latter two factors with behaviours, significantly genetically influenced rather than the chemical composition of the so-called “junk food”. Or am I wrong? Denis 80 year old Engineer from Dublin still enjoying “me meat ‘n potatoes”, white bread and jam sambos,,,,,you get the point!
Seems to me, and it would be a big ask, that requesting if they can get you a 'names redacted' list, so that you can have the size information & value of the suit while protecting personal information.
Couldnt you just sent a spreadsheet to the the tailor, they put in the data, and then it simply spits out the date at which the transition took place ? They wouldn't even send BMI's ? which is probably all you need. Or how about getting normalized data ?
What about the generations of humans that lived on weak alcoholic beverages as an alternative to clean drinking water hundreds of years ago? Were they more likely to have cancer? Most humans 1-2 hundred years ago relyed on weak alcohol because clean drinking water was hard to obtain and very unreliable
Wow, how did I not know that alcohol itself increases the risk of cancer? Thankfully I myself never drank alcohol, despite the pressure from everyone. Where I live, not drinking alcohol (especially as an adult) is considered lame and childish. Guess the european country. No: actually guess the crumbling abomination that we have the audacity to call a "country".
The fox experiment really SHOULD introduce everyone to Pleiotropy, Poygenetic inheritance, mosaicism, Developmental windows (YOU CLEARLY HAVE THESE, alhtough from the very specific ways in which traits are prevented from closure through consistent behavioral actions, BEFORE human brain maturation, even highly preserved epigenetic and transcriptional silencing are affected by top-down behavior, as well as upwards from the molecular) and Neoteny. Habituation is one emotiocognitive trait cluster that is above, conflated with "intelligence." It is better hypothesized as often neotenic relationship. The Gray Wolf, for example, passes a developmental window , the very one involved in "tameness" as characterized by Belyayev et alia. And Gaze Following IS a trait maintained within the wolf ingroups, though not recorded across species which they would benefit from observing. That is a Red Wolf on Dr Sapolsky's shirt, which has some genetic identity with Canis latrans, as well as some unique alleles of Canis lupus. Common mammalian prey of cursorial predators DOES tend to follow the 20kg predator size choice in prey change. Red Wolves may be an exception due to old endemic mosquito-borne heartworm nematodes, though climate change hand human domestic spread has caused proliferation of that parasite. It appeard that red wolves have, or had some resistance to the disease. England, and all of Europe persisted in violently hating canids, and extirpating them as much as possible, up through this moment. Foxes are mesopredators, which oddly, are benefited by wolf presence, as 9j North America, the persecution of wolves led the mesopredator coyote to become both far mroe abungant, and expand its range in areas where paleozoologists had never found coyote during the long period of Canis lupus presence. And Doc, I do most vehemently NOT find the neotenous trait of pug noses to be more endearing than the craggy pointed head of wolves or the pointy muzzle of coyote. We are all mosaic, even chimeric, which remark i hope will stimulate readers to explore.
If I remember correctly, the foxes were also bred from the most aggressive ones. The result were very unlikable violent little monsters. This would seem to counteract the assumption that they were almost cute to begin with.
They are multiple generations removed from their ability to ever again live in their natural habitat. There are a few organizations trying to rescue them and let them live more freely. Most have never been outside the factory. For more info, see Save A Fox Corporation. Very inspirational.
Why couldn't they give you the data without names? Or you could agree to never publish anything but the trends? That study would be worth trying again. It would seem all you need is the time and size of the suit, not who owned it.
"Off switch" = Stop codons. Cells are marvelous, communicative organisms, and tumor cells also signal other replications, for example, completely normal cells that increase vascularization. Thus the concept of "randomness" is not a concept you should file under "maybe something won't affect ME!" Tumor cells, just like actively exercised cells of any type, signal "i need food!" and with a bit of ingroup insistence, get their way, and induce better feeding tubing to themselves. They have the pizza app. You have to love Henrietta Lacks' cells, still asking for their menus 75 years after she's gone. (my sister, btw, along with two of the two other women i have long contact with, slugs down her vino, sans veritas concerning the cancers all three have chosen to express. Attribution of 10%, too Vegasy for me to credit. The House WILL still win.)
Talking about foxes. Sure, you know, but there is another part of the same experiment. Some of the foxes were chosen for aggressive behavior towards humans. The results were also pretty interesting.
Did women live longer after the introduction of birth control instead of being baby machines. In family records the men seem to go through multiple wives.
Professor Sapolsky, I am a loyal listener of yours and I just want to say that this series of yours is not only very educational but also extremely cute and lovely, I get up every morning and listen to an episode that puts me in a good mood and motivates me to learn new things for the day, thank you! Happy anniversary! ❤
I recently quit drinking. The transformation I underwent was startling. In barely over a month, I lost 20 lbs, now I can run for miles, effortlessly, I feel incredible, and every aspect of my life has improved dramatically. Before I quit drinking, I did the math and discovered that I was drinking 1500 calories of beer a day. Luckily, I had only started drinking fairly recently, only drinking heavily for less than 10 years. I'm 48, now.
Happy anniversary to the Sapolsky parents :)
You had me at Winston Churchill’s ass! Then I was in awe to hear you spread the word about alcohol’s connection to cancer (I’m an RN turned Oncology Data Specialist and I collect this info for research) and we ended with pure delight hearing the Siberian Fox domestication story (I watched a documentary about this years ago)! THANK YOU Dr. Sapolsky and your wonderful offspring! Congratulations on 35 years with your mate! 🥳💖🫶🏼 sending love to this whole community!
I haven't watched it yes, so I am still wondering. Did Winston have a donkey or...............
This man is so so good. As a teacher he is my very idol ❤
His teaching gift is definitely a reason to idolize Dr. Sapolsky!
0:24 This moment was almost too sweet for an episode called Winston Churchill's ass
Yes! 🥹
I saw a recent video on Startalk interviewing David Speigal, also of Stanford, talking about hypnosis.
I would be interested in your thoughts about how it can be used to control or modify parts of the brain. Specifically related to depression and anxiety.
Happy Anniversary as well!
My wife and I will celebrate our 33rd in May.
When I got home from Vietnam I didn't realize I was suffering from PTSD. The heavy drinking and assorted drugs seemed to help. I also did a lot of heavy thinking and it occurred to me one day that cause and effect could be traced backwards to the beginning of time as we know it. When I came across your absence of free will presentations a couple years ago I was and am very impressed. Keep up the good work! ~ : )
… and you stopped drinking alcohol?
Wonderful, thankyou, and wonderfully
funny to boot.
YEP! I knew it! A small stream hearabouts is know as a CRIK!
Buon anniversario and let me tell you that every Thursday for me is much more better knowing that there's a new episode. Thank you professor and thank you offspring.
What a fascinating family you all are! Your TH-cam channel is even more informative than my local community college. Thank you for welcoming us into your home! Happy Anniversary! 🎉
I really appreciate these segments on alcohol damage, for real
You are an amazing human being. ❤
This, like all your work, is unbelievably great! Bravo!
Delightful! Thank you once again for an interesting episode. Congratulations to Professor Sapolsky and his wife on their wedding anniversary. I think that I will watch one of the lecture series yet again... every time I watch them, I find something that I missed before.
me too
Crazy about your work, have all your books. You might try one of the New England versions of exclusive tailoring, J Press, New Haven.
It seems the northern elephant seal has the highest male/female lifespan discrepancy of all mammals. 50%! Wow! Happy anniversary Doc. Thanks for the video.
Awww…happy anniversary to an adorably slim couple!
"How to Tame a Fox [and build a dog]" - Lyudmila Trut
Agreed, a fantastic read.
I've been a huge fan since I read Behave 5 years ago and have watched every episode. All are fascinating. But this one seemed especially so. I listened with rapt attention. It is so interesting to learn about the switch from rich people obesity to poor people obesity. So sorry about your data request being denied. Gosh darn lawyers anyway. I had not heard about the surgeon general's pronouncement that alcohol is a carcinogen. I quit drinking 3 years ago at 66. I wish I'd never started. And the effects of breeding foxes for domestication having the surprising effect on their appearance. Fascinating! These videos always lift my mood, which is a miracle in today's political environment. Thank you both so much!
great episode, other than the alcohol section, I laughed all the way through, and I hope you find that whistleblower, the world deserves to know about Churchill's ass. ;)
Happy Anniversary you two! My wife and I celebrated our 35th anniversary on the 12th. Small world! I love this channel!
Is that the little girl that was helping Professor Sapolsky get baboon vitals in that old clip!? Wow! All grown up and still fascinated with papas work. Love to see it! ❤️ Its so wholesome
Thank you for all you do, happy anniversary!
Thank you, professor!
Thanks a lot sir for this new scientific podcast. As a Romania who transitioned the horrible period from a centralized economy to the free market one after the collapse of communism in the Eastern Europe I confirm your analysis on why so many males lived less than women. I knew a lot of my own friends , I'm 66, that did not make it through that period of massive job losses and lack of any hope and mostly of an uncertain future. Alcohol was the main killer of my friends and acquaintances.
We need to keep the research project alive!
Happy Anniversary Doctors!
I think it's *Drs
I made a quick search for that gene in foxes, GTF 2I (general transcription factor, initiator). Robert mentioned it before in dog episode ☝. There is a strong connection between dog hypersociality and modification in that gene (compared to wolves who have it intact). As well in humans GTF 2I possibly makes for hypersociality, when one gene copy is lost with chromosom 7 aberration (elven syndrome). I found one fox study only, they do not conform differences in GTF 2I in domesticated and wild foxes. Yet samples are exploratory, genomes of 5-10 animals 💁♂
Banger!
Thank you 🎉❤
Happy Anniversary to you both!
Now _that's_ a title! Happy 35th anniversary!
Another wonderful Episode and Thank you so much for sharing such a great information. btw hope next time you would talk about felines ...
Your work has explored the intricate interplay of biology, environment, and behavior, often breaking down deterministic views of human nature. But what if consciousness itself is not confined to individual brains? What if thought can be shared, accessed, or transmitted beyond the structures we currently understand?
I am so excited about the picture on Mr. Sapolsky's shirt: is that really a Canis lupus?! Could you please say a word about the phenomenon of people's fear of wolves and their ecological role? How has the wolf shaped people socially historically? What is the connection between wolves and dog breeds today?
Btw: Thx for the great episodes!!
I particularly enjoyed the discussion of alcohol and cancer. Thanks for the info..
What a shame that a great idea was lost due to the terrible idea of legal liability.
I would not say legal liability is a terrible idea, if some evil corporation is poisoning your drinking water, you'll probably want them held accountable. As with anything it just depends how it's applied. With personal data, it can be de-identified for research, which I'm surprised wasn't Robert's next question on that phone call.
@PinataOblongata I think you extrapolated on the point way beyond its intention. Obviously, any society that is expected to function requires rules. Ugh....
Is that a moo deng reference in this week's edition of Sapolsky-Offspring Interviews
Moo deng moo deng moo deng 🦛
Absolutely amazing every time 👍
Love the way you explain everything 👍
Happy Anniversary!
Omg. This is the best TH-cam series in history of our shared reality! Thank you! I love you too!
Great story ❤️
Thank you
Excellent work, offspring.
Start a petition to the Savile Row legal department, we'll all sign!
i missed savile row....help
I'm on board! Keep the research alive!
Happy Anniversary
10:59 Ah, it’s quite the revelation, isn’t it? Knowing that even Dr. Sapolsky, with all his brilliance, feels a tad... primitive when graced by the refined tones of a proper British accent. It’s rather comforting, really-like realizing even the great minds can be titillated by the Queen’s English!
Lol what's it ?
Fascinating.🤔
So much great content! I love this series and your books. And Happy Anniversary!!
I have a question - I’m interested to learn how exercise affects brain function and mental health, and also how it affects the health of other organs in the body? We often hear about how the brain communicates with our muscles. But we don’t hear about how our muscles communicate with the brain and other organs. When we do strenuous work or exercise, what are our muscles doing that produce such benefits for the rest of our body? Lastly, I’ve read there are benefits at the cellular level related to mitochondria and gene replication. What is that all about? Thank you!
Happy Anniversary 👏👏👏
spontaneously indeed
Merci vous deux 💗
Congrats on making it though to 35... :)
🎉Congratulations !
✨️Happy Anniversary ❤🎉
Dear professor, as a depressed conflicted animal in a foreign land who doesn't know the people language, doesn't want to partake in default society groups but seeks to find their own people in comedy clubs and chess clubs or even neurology, language clubs. What do you suggest to do to survive and thrive? An individual can live their life without sacrificing their freedom of rights? How to practice social interaction without getting harmed or being harmed? Thank you for being awesome as ever.
Moldova mentioned! 🇲🇩🇲🇩🇲🇩
thanks ❤
Hello sir Sapolsky
Thanks, Sapolsky clan, I’m a fan, a reader of your books , Mr.
Quibble: “Junk food” and nutrition and obesity: I’m inclined to link the latter two factors with behaviours, significantly genetically influenced rather than the chemical composition of the so-called “junk food”.
Or am I wrong?
Denis
80 year old Engineer from Dublin still enjoying “me meat ‘n potatoes”, white bread and jam sambos,,,,,you get the point!
⚡ EXCELLENT CONTENT⚡©®™
thanyou and family, as im a lrnnin plenty, prof and awwespring
I have a badger living in its sett in 'our' garden some 30 feet from my backdoor. He has domesticated me.
Seems to me, and it would be a big ask, that requesting if they can get you a 'names redacted' list, so that you can have the size information & value of the suit while protecting personal information.
Couldnt you just sent a spreadsheet to the the tailor, they put in the data, and then it simply spits out the date at which the transition took place ?
They wouldn't even send BMI's ? which is probably all you need.
Or how about getting normalized data ?
What about the generations of humans that lived on weak alcoholic beverages as an alternative to clean drinking water hundreds of years ago? Were they more likely to have cancer? Most humans 1-2 hundred years ago relyed on weak alcohol because clean drinking water was hard to obtain and very unreliable
Wow, how did I not know that alcohol itself increases the risk of cancer? Thankfully I myself never drank alcohol, despite the pressure from everyone. Where I live, not drinking alcohol (especially as an adult) is considered lame and childish. Guess the european country. No: actually guess the crumbling abomination that we have the audacity to call a "country".
if alexander mcqueen was alive he would probably be interested as he used to work in saville row…
or maybe
The fox experiment really SHOULD introduce everyone to Pleiotropy, Poygenetic inheritance, mosaicism, Developmental windows (YOU CLEARLY HAVE THESE, alhtough from the very specific ways in which traits are prevented from closure through consistent behavioral actions, BEFORE human brain maturation, even highly preserved epigenetic and transcriptional silencing are affected by top-down behavior, as well as upwards from the molecular) and Neoteny.
Habituation is one emotiocognitive trait cluster that is above, conflated with "intelligence." It is better hypothesized as often neotenic relationship.
The Gray Wolf, for example, passes a developmental window , the very one involved in "tameness" as characterized by Belyayev et alia.
And Gaze Following IS a trait maintained within the wolf ingroups, though not recorded across species which they would benefit from observing.
That is a Red Wolf on Dr Sapolsky's shirt, which has some genetic identity with Canis latrans, as well as some unique alleles of Canis lupus.
Common mammalian prey of cursorial predators DOES tend to follow the 20kg predator size choice in prey change. Red Wolves may be an exception due to old endemic mosquito-borne heartworm nematodes, though climate change hand human domestic spread has caused proliferation of that parasite.
It appeard that red wolves have, or had some resistance to the disease.
England, and all of Europe persisted in violently hating canids, and extirpating them as much as possible, up through this moment.
Foxes are mesopredators, which oddly, are benefited by wolf presence, as 9j North America, the persecution of wolves led the mesopredator coyote to become both far mroe abungant, and expand its range in areas where paleozoologists had never found coyote during the long period of Canis lupus presence.
And Doc, I do most vehemently NOT find the neotenous trait of pug noses to be more endearing than the craggy pointed head of wolves or the pointy muzzle of coyote.
We are all mosaic, even chimeric, which remark i hope will stimulate readers to explore.
so, human self-domestication next?
If I remember correctly, the foxes were also bred from the most aggressive ones. The result were very unlikable violent little monsters. This would seem to counteract the assumption that they were almost cute to begin with.
There are still many, many fox fur "farms" in North America. Thanks to Prada, Gucci, etc...😢
☹️
They are multiple generations removed from their ability to ever again live in their natural habitat.
There are a few organizations trying to rescue them and let them live more freely. Most have never been outside the factory. For more info, see Save A Fox Corporation. Very inspirational.
Why couldn't they give you the data without names? Or you could agree to never publish anything but the trends? That study would be worth trying again. It would seem all you need is the time and size of the suit, not who owned it.
"Off switch" = Stop codons.
Cells are marvelous, communicative organisms, and tumor cells also signal other replications, for example, completely normal cells that increase vascularization. Thus the concept of "randomness" is not a concept you should file under "maybe something won't affect ME!"
Tumor cells, just like actively exercised cells of any type, signal "i need food!" and with a bit of ingroup insistence, get their way, and induce better feeding tubing to themselves. They have the pizza app.
You have to love Henrietta Lacks' cells, still asking for their menus 75 years after she's gone.
(my sister, btw, along with two of the two other women i have long contact with, slugs down her vino, sans veritas concerning the cancers all three have chosen to express.
Attribution of 10%, too Vegasy for me to credit.
The House WILL still win.)
Talking about foxes. Sure, you know, but there is another part of the same experiment. Some of the foxes were chosen for aggressive behavior towards humans. The results were also pretty interesting.
orange cats explained
Let’s stick to serious questions here not nonsense
This is an interesting counterpoint relative to alcohol and cancer th-cam.com/video/F5sDzukarN8/w-d-xo.htmlsi=3r9taePnwA37LqFm
@@dougtunison I watched. Yes, interesting. Thx for sharing.
Did women live longer after the introduction of birth control instead of being baby machines. In family records the men seem to go through multiple wives.
So, Winston Churchill had a donkey?!!
Sir please recommend my Harvard Graduate Application
huh? I thought it was pregnancy that caused the female lower lifespan 1900s etc
sen bu dünyadan değilsin. Kesinlikle değilsin...
I think a woman that goes out to collect the water is going to live longer than the woman that learns to turn the tap water on in her kitchen.
Yes, if all she’s doing is collecting the water! He did say “worked to death” and he means that literally.