Virology Lectures 2023 #4: Structure of viruses

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  • เผยแพร่เมื่อ 31 พ.ค. 2024
  • Viral particles are a paradox: they must protect the genome in its journey among hosts, but also come apart under the right conditions to release the genome into cells, a property called metastability. This lecture explores the two major forms of symmetry for building virus particles, helical and icosahedral. We discuss quasi equivalence; how to make larger viruses by increasing the triangulation number; and the lipid envelope and its glycoproteins derived from the host cell.
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ความคิดเห็น •

  • @sandvich101
    @sandvich101 ปีที่แล้ว +6

    Uploading columbia lectures is such a godsend fr. I love learning virology thru these videos while i do my other actual bio course work at uni. You make it really interesting Vincent!

  • @janntcyberunclenicky7553
    @janntcyberunclenicky7553 6 หลายเดือนก่อน +1

    I have benefitted a lot from this class. My name is Gwengi - a student of pharmacy in Kenya

  • @MrJessie51
    @MrJessie51 4 หลายเดือนก่อน

    According to my text book, school notes, google AI bard , and Oxford dictionary the nucleocapsid refers to the capsid together with the nucleic acid it encloses. So that might be why so many are confused when you say your definition because nucleocapsid according to the other sources would be found in non enveloped and enveloped viruses

  • @zhansayabauyrzhanova2492
    @zhansayabauyrzhanova2492 4 หลายเดือนก่อน

    Thanks, watching from Kazakhstan

  • @michaelchicchelly7522
    @michaelchicchelly7522 ปีที่แล้ว +1

    Excellent

  • @lmug1
    @lmug1 ปีที่แล้ว +1

    Thanks for another lecture, it was great!

  • @rukaiyamemon9908
    @rukaiyamemon9908 4 หลายเดือนก่อน

    Thanks proff its very helpful...❤

  • @paul3116
    @paul3116 ปีที่แล้ว

    Thanks Vincent! Amazing lecture!!

  • @f.scott.fitzbeagle
    @f.scott.fitzbeagle ปีที่แล้ว +1

    Looking at the illustrations of viruses early in this lecture, I am surprised by the similarity between the viral illustrations and photographs of diatoms.

  • @dediosp16
    @dediosp16 ปีที่แล้ว +2

    thank you Vincent ,i enjoy the learning i get from your shows...

  • @MrKaidman
    @MrKaidman ปีที่แล้ว +1

    Ty for this

  • @pked9
    @pked9 ปีที่แล้ว

    Thanks Vincent! Amazing lecture ....

  • @FuerteDoctora
    @FuerteDoctora 5 หลายเดือนก่อน

    Thank you professor 💚💚

  • @bohdanoryshkevich2140
    @bohdanoryshkevich2140 ปีที่แล้ว +1

    I have a question. Does influenza virus have eight different nucleocapsids, one for each ot its -RNA segments? If so is that what defines its helical nature?😮 The virion image appears globular. I assume that is so because of the encompassing membrane? Thank you for answering this question. I did not catch this nuance in your previous versions of this lecture!

    • @zhansayabauyrzhanova2492
      @zhansayabauyrzhanova2492 4 หลายเดือนก่อน

      I think so, he grouped viral structure by capsid / nucleocapsid structure, , not by their structure itself. Even if the if Ebolavirus looked like round as influenza, it would stay as helical, not isohedrical.

  • @f.scott.fitzbeagle
    @f.scott.fitzbeagle ปีที่แล้ว

    "The bonding contacts of subunits are usually non-covalent." Are they not always non-covalent?

  • @middlevoids
    @middlevoids ปีที่แล้ว

    Don't get the term meta-stable in context of the protective role for viral genome

  • @pked9
    @pked9 ปีที่แล้ว

    the mic bites on this one.....