I am so excited for my interview tomorrow at a compounding pharmacy after watching this video. Thank you for making me realize I want to do this as a living even more!
In germany we compound capsules a little bit different. We don't calc the amount for the filling agent. We "dilute" the active ingredients a little bit and fill it in the capsules, then we fill up all capsule before dumpung it all back in the mortar to homogenize. Then we fill em up. Sometimes we also have graduated cylinders with a mark (10 cps, 20 cps, 100 etc) and fill it up 3/4 w/ the filler, add the diluted active ingredients and fill it up to the mark, homogenize and fill. We never hand punch, even when its just like 10 caps. We just stick some tape over the remaining holes in the capsule filler😅
Wow. Thanks for showing this. It's pretty mind-blowing for the layperson. It appears like there could be a lot of room for error. For instance, how can you be sure the mixed powder is mixed perfectly even? (What if there's more of one of the ingredients in one section of the glass mortar? Can't one of the capsules end up with more of one ingredient and less of another?) I guess my disconnect is because these are solids. To me, it would seem like liquids could be mixed more evenly, but of course I realize you can't put liquids in these capsules. I'm also curious, at 4:51 in the video, how is the +/-10% figure arrived at?
Pharmacy student here. The powder mixture should be triturated (mixed together) long enough so that equal distribution of powder is achieved. The geometric dilution method also helps with this. As for the +/- 10%, it is the industry standard acceptable weight limits (as far as i know, of course you can check the US pharmacopeia to be sure)
@@DonnaAndCats happy to help! It's also important to note that these types of compounding jobs are only done for specialty medications (such as when a patient needs a particular dose that isn't commercially available) or by compounding pharmacies (though all pharmacists are trained to do this, not all pharmacies have the proper equipment for compounding jobs)
So I have a capsule press which allows me to load 100 capsules equally by pouring the mixture into the grid which evens each capsule to near exact equal amounts. My ingredients are 100% organically sourced and are mostly different herbal and mushroom blends which require specific amounts in each capsule i.e. 100mg x 7 different types of mushroom powders into one capsule. If all calculations and bulk measurements are done correct following the method in this video, then is this an efficient way to accurately make my capsules? Can I be assured that by adding the correct amount individually to the mixture and thoroughly mixing in as demonstrated here that my capsules would have the desired amount of ingredient per capsule? I'm based in the UK so industry standard's and regulations will need to be taken into account. Any feedback is greatly appreciated, thank you.
I'm trying to fill 5 different powders to one capsule but I have a stumbling block and need help. Can someone show me the way. The video is a bit too fast for me and I'm not understanding it very well. Thanks
I am so excited for my interview tomorrow at a compounding pharmacy after watching this video. Thank you for making me realize I want to do this as a living even more!
Good luck with the interview! We hope you get the job and love it!
@@pharmacistplace thank you so much!
That was so enjoyable to watch
In germany we compound capsules a little bit different. We don't calc the amount for the filling agent. We "dilute" the active ingredients a little bit and fill it in the capsules, then we fill up all capsule before dumpung it all back in the mortar to homogenize. Then we fill em up. Sometimes we also have graduated cylinders with a mark (10 cps, 20 cps, 100 etc) and fill it up 3/4 w/ the filler, add the diluted active ingredients and fill it up to the mark, homogenize and fill. We never hand punch, even when its just like 10 caps. We just stick some tape over the remaining holes in the capsule filler😅
I really appreciate your work... i want to see more and more. Keep it up
Thank you so much 😀
Wow. Thanks for showing this. It's pretty mind-blowing for the layperson. It appears like there could be a lot of room for error.
For instance, how can you be sure the mixed powder is mixed perfectly even? (What if there's more of one of the ingredients in one section of the glass mortar? Can't one of the capsules end up with more of one ingredient and less of another?)
I guess my disconnect is because these are solids. To me, it would seem like liquids could be mixed more evenly, but of course I realize you can't put liquids in these capsules.
I'm also curious, at 4:51 in the video, how is the +/-10% figure arrived at?
Pharmacy student here. The powder mixture should be triturated (mixed together) long enough so that equal distribution of powder is achieved. The geometric dilution method also helps with this. As for the +/- 10%, it is the industry standard acceptable weight limits (as far as i know, of course you can check the US pharmacopeia to be sure)
@@thespqrguy Thanks for helping it make a little more sense to a layperson like me! :)
@@DonnaAndCats happy to help! It's also important to note that these types of compounding jobs are only done for specialty medications (such as when a patient needs a particular dose that isn't commercially available) or by compounding pharmacies (though all pharmacists are trained to do this, not all pharmacies have the proper equipment for compounding jobs)
So I have a capsule press which allows me to load 100 capsules equally by pouring the mixture into the grid which evens each capsule to near exact equal amounts. My ingredients are 100% organically sourced and are mostly different herbal and mushroom blends which require specific amounts in each capsule i.e. 100mg x 7 different types of mushroom powders into one capsule. If all calculations and bulk measurements are done correct following the method in this video, then is this an efficient way to accurately make my capsules? Can I be assured that by adding the correct amount individually to the mixture and thoroughly mixing in as demonstrated here that my capsules would have the desired amount of ingredient per capsule? I'm based in the UK so industry standard's and regulations will need to be taken into account. Any feedback is greatly appreciated, thank you.
I'm trying to fill 5 different powders to one capsule but I have a stumbling block and need help. Can someone show me the way. The video is a bit too fast for me and I'm not understanding it very well. Thanks
could you say where that 455 mg came from?