Peptidoglycan | Peptidoglycan structure | Biochemistry

This video explains about Peptidoglycan and structure of peptidoglycan.
Peptidoglycan is made up of NAM (N-acetyl Muramic acid) and NAG (N-acetyle Glucosamine) linked with Beta 1 4 glycosidic bond.
Peptidoglycan is heteropolysaccharide and Peptidoglycan is found in cell wall of bacteria so it is call structural polysaccharide.
Peptidoglycan is 3D mesh like structure having pentaglycine interbridge. Pentaglycine interbridge is formed by an enzyme called D D Transpeptidase. Penicillin binds to Transpeptidase enzyme and blocks its activity hence the cellwall systhesis is inhibited and bacteria die.

[@vartanazo1694]

Muchas gracias, Thankk you Very much, you have helped me a lot with this majesty explanation jejejjee, greetings from Chile

[@SandipsBiology]

I am glad to help you! 🙂

[@yinyang.333]

Totally agree bro, because even when I was looking for such kinda explaination I cont get after 100 video search, all just shows you to mug structure names. This guy is really underrated

[@aasthapriya8120]

Thank you so much sir for this....I usually don't comment guys but right now at 2am because of this topic I was literally having a mental breakdown... thanks to teachers like you on TH-cam who save us!

[@goutamsbiologygoutamchoudh2921]

Superb, concept is now crystal clear

[@yaminisunkara9316]

The best explanation. Thank you so much sir

[@navpreetkaur5121]

Very nicely explained.....thanks

[@phearenkit849]

Thanks. Your lecture is very helpful.

[@eysheedutta7710]

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[@s.sambath2202]

Brilliant class dear sir

[@amrinansari3869]

Very well teaching sir .. 👍

[@gauravyadav2530]

Sir explain very unique nice 👍

[@Livelong413]

very well explained sir

[@mohammadashraf9177]

Excellent professor in india

[@poojasoni1407]

Woww.... thank you so much sir....you just nailed it....you just made this topic so so easy that even if I don't study it , I can write it on exam day directly.... thanks a lot.....keep your good work going....

[@SandipsBiology]

Thank you!

[@Alvatheathlete]

Thank you! Super helpful

[@pavitkaur4948]

Awesome lecture...... seriously concept is made so easy ....thanx a lot sir....it was very helpful

[@SandipsBiology]

Thank you!

[@francismannion7075]

Thank you for a great explanation it was very clear and well presented.

[@SandipsBiology]

Thank you!

[@gamingsaiyanyt6492]

Sir your videos are really very helpful for me 🙂 thank you so much sir for posting them😀
why you stopped posting them??
If possible then please start posting videos again🙏

[@rosaljvrdi8009]

Very helpful. Thank you .

[@vinhlethihong4544]

I am much obliged to you for your video. It helps m a lot

[@SandipsBiology]

I am glad to help you! 🙂

[@musicstyle3825]

Thanks sir this explains of nag and nam

[@K_Singh.]

Very helpful video.....
Thank u so much sir...

[@SandipsBiology]

Glad to hear that my video helped you!

[@md.rashedulkabir8175]

thanks a lot,sir

[@aparnaprajapati9461]

Very helpful sir ....thank you😊

[@SandipsBiology]

Glad to hear that my video helped you!

[@zahraamahmoud5661]

Awesome thank you very much
❤️

[@SandipsBiology]

You're welcome!

[@Sweta_thakur711]

Well explained ...thank u sir ..

[@SandipsBiology]

Welcome!

[@pallavishende8350]

Very well explained sir, it really help me in my exam

[@SandipsBiology]

Thank you!

[@chenikayadav1057]

Sir plzz make a vedio on structure of proteins in detail ( biochemistry part)

[@rubi22teresa]

Thanks

[@rahulkanetkar6710]

Thank you so much sir

[@SandipsBiology]

You’re welcome!

[@haseeburrahman8653]

sir thanks alot

[@spinni9768]

very helpful!!

[@SandipsBiology]

+Spinni97 Thank you! I am glad that you found my video helpful!

[@dakshsharma1703]

Thank you so much Sir☺️

[@SandipsBiology]

You're welcome!

[@mansarasirpali8287]

thank you soo much..

[@SandipsBiology]

Welcome!

[@huleshsahu7251]

Good....

[@SandipsBiology]

Thank you! :)

[@tahirsmedicalandbiologyvid4969]

sooper

[@archanayadav8674]

mast sir jii😘

[@SandipsBiology]

+Archana Yadav Thank you! :)

[@naddn5321]

One question sir, this is one peptidoglycan layer - but is it conected with upper and lower ones? Lets say this is one piece o paper (what you explained), but how is pile of papers connected? Thank you very much! :)

[@yinyang.333]

There is no pile of papers. You just increase the the thickness of one paper instead of stacking different different papers and joining them, there is a difference between the two process that you should appreciate, so in former process the whole paper essential remain one molecule of peptidoglycan and That's why gram positive Bacteria are easily susceptible to antibiotics, because even if layer is thich but it can be broken easily by an antibiotic.

[@arundhoni7027]

tq

[@SandipsBiology]

You're welcome!

[@ladlyperween.6183]

sir samaj mein aagya pr..ek jagah confusion hai..sir apne NAG m primary amine aur actyl grp lgaya hai..tb tk dusre side mein koi change nhi hua hai..pr jaise hi NAM banaye to usme aachanak se primary amine or acetly grp lga diya..to ques ye hai sir jis samay aap NAG mein change kr rhe the to NAM mein bhi sath sath change krna hai..plz sir reply

[@SandipsBiology]

Actually, jab bacteria mein cell wall synthesis hota hai tab NAG & NAM pehle se hi produced hote hai, sirf ye NAG & NAM monomers jud ke polymer banate hai. Structure ko samjne mein aasani ho es liye meine es tarike se steps mein samjaya hain. Hope this helps!

[@ladlyperween.6183]

+Sandip's Biology not really sir..mera mtlb jab NAG m primary amine aur acetyl grp legega to sath sath NAM m bhi lge g

[@SandipsBiology]

Haa lagenge. NAG + Lactate = structure of NAM

[@deepakbisht4805]

Hello Sir ,ye topic lehninger biochemistry book mai hoga

[@deepakbisht4805]

Sir ye topic kiss book mai milega bta dijiye 🙏🙏

[@SandipsBiology]

Lehninger

[@deepakbisht4805]

@@SandipsBiology okay sir tysm🙏🙏

[@karanveerthakur4041]

5:30 You didn‘t draw Lactate but Propionate

[@SandipsBiology]

Yes, but at 8:17 it is correct

[@amrzein9949]

Why is everyone Indian

[@poongodimahendran9209]

Onnupurriyala tamilanadathanaava purriyathu ethulanee Englishlanadathar 🤣🤣🤣🤣🤣🤣

[@SandipsBiology]

Didn't get you. Could you please translate this into English? 😃

[@royalbeast9034]

I don't understand 😠😠🤯🤯🤯🤯🤯🤯🤯🤯🤯🤯🤯🤯🤯

[@sreenidhi136]

Very helpful! Thank you

[@SandipsBiology]

You're welcome!