VDJ recombination | antibody class switching

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  • เผยแพร่เมื่อ 22 ก.ย. 2016
  • VDJ recombination lecture - This lecture explains about the mechanism of antibody class switching and somatic mutation that leads to the development of antibodies by the plasma cells. Plasma cells undergo genetic VDJ recombination that allows them to shuffle DNA segment between variable region of antibody which helps in the generation of different types of antibody modifications. This process is known as antibody class switching when the antibody class is switched from one type to the other.
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    Thank you for watching the VDJ recombination and antibody class switching video lecture in immunology.

ความคิดเห็น • 290

  • @ju6305
    @ju6305 3 ปีที่แล้ว +153

    Idk how much this man gets paid but it should be at least the amount of an amazing doctor because he has saved my life multiple times

    • @shibaghosh1817
      @shibaghosh1817 2 ปีที่แล้ว +11

      Don't worry, He earns more than a doctor, He is the best biology teacher in our West Bengal.

    • @microbiologywithshafaq1411
      @microbiologywithshafaq1411 ปีที่แล้ว

      Agreed

    • @hardikdubey730
      @hardikdubey730 9 หลายเดือนก่อน +2

      One of the best since my childhood

  • @nishattasnim9549
    @nishattasnim9549 2 ปีที่แล้ว +46

    I'm just paying the University for degree, whereas you make me understand each and every concept clearly. Thank you sir. Lots of respect from Kolkata ☆

  • @maishapoushi231
    @maishapoushi231 3 ปีที่แล้ว +9

    i am a medical student myself,& i honestly owe u due to your crystal clear xplanations. your speed,the precision of concepts & the accuracy summed up with ur confident presentation is what makes this immunology concept amazing!
    b4 my xams,it was a life saviour! so thank youuu

  • @dawnhoran3353
    @dawnhoran3353 7 ปีที่แล้ว +22

    Once again a brilliantly clear lecture making it easier to understand this complex subject, thank you so much!

  • @pranjalimahamuni-badiger2873
    @pranjalimahamuni-badiger2873 ปีที่แล้ว +7

    No one can explain in such a excellent way.. thanku

  • @saloniprasad9739
    @saloniprasad9739 ปีที่แล้ว +6

    I opened kuby book I was confused with how this switching taking place but within a mints I got the concept
    Thnks sir for your precious vedios n hardworking✨👑
    I admire n thank ful for u everytime I comes here to serch any topics ❤️💎

  • @anupamupadhyay1677
    @anupamupadhyay1677 7 ปีที่แล้ว +2

    thank you so much shomu your selfless action of spreading knowledge among the dummies. We are very gratefull to you and not to mention you are just awesome in terms of expression and are really an expert.

  • @Sneha-hc3wm
    @Sneha-hc3wm 4 ปีที่แล้ว +13

    2 days away form my biology exam and you saved my life!! THANK YOU SIR!!

  • @aboutstudies766
    @aboutstudies766 6 ปีที่แล้ว +1

    Clearly explained Sir. Thank you very much.

  • @ramshajawed1716
    @ramshajawed1716 2 ปีที่แล้ว +9

    Sir you saved my semester really thankful to you ☺️

  • @diya3095
    @diya3095 6 ปีที่แล้ว +1

    Genius ...thnks alot from kashmir

  • @meghapatel1683
    @meghapatel1683 6 ปีที่แล้ว +2

    You made it much easier! Thank you

  • @doctorofmedicine1113
    @doctorofmedicine1113 5 ปีที่แล้ว +4

    This is what i was searching for ..
    And free finally got from my best.....

  • @naomigu8131
    @naomigu8131 5 ปีที่แล้ว +7

    you’re so good at explaining things, thank you for clarifying this, just wondering if you have a video on T cell receptor diversity?

  • @amanyasharon5227
    @amanyasharon5227 6 ปีที่แล้ว

    Very informative lecture, Thank you very much

  • @aathmikagovindh733
    @aathmikagovindh733 6 ปีที่แล้ว

    Thanks a lot sir the video solved all my doubts and confusions

  • @saniyashah7846
    @saniyashah7846 7 ปีที่แล้ว +1

    thanks a lot shomu....ur lectures have been helpfull to me olwz

  • @mumthaspk6616
    @mumthaspk6616 4 ปีที่แล้ว

    I'm watching the vedio in 2020 it's so easy to understand. Thank you

  • @garimarai7588
    @garimarai7588 5 ปีที่แล้ว +1

    sir i just started to see your video from this month. and i m loving the way u explain

  • @kainatrehman7384
    @kainatrehman7384 6 ปีที่แล้ว

    my immunology teacher suggested me to watch thiz video:)...nd its amzaing sir...

  • @vipulkumar2726
    @vipulkumar2726 7 ปีที่แล้ว

    superb explanation sir...

  • @shriyamahajan811
    @shriyamahajan811 ปีที่แล้ว +2

    How you teach soooo soo well. It just get straight into the mind. Thank you so much sir.☠🤍🤍

  • @viveksinghchauhan7496
    @viveksinghchauhan7496 5 ปีที่แล้ว +2

    Respect level up !!! After seeing this video.

  • @reevaabc9159
    @reevaabc9159 หลายเดือนก่อน

    thanks shomu after 7 years you are still #1

  • @starnancy6173
    @starnancy6173 4 ปีที่แล้ว +5

    Literally you are very hardworking guy..one thing that I can learn from you is Consistency..Hats off to you..

  • @vishnudasan3711
    @vishnudasan3711 7 ปีที่แล้ว +1

    clear explanation sir

  • @tajpreetpadda4780
    @tajpreetpadda4780 6 ปีที่แล้ว +3

    Super helpful!!

  • @amansharma7737
    @amansharma7737 7 ปีที่แล้ว +1

    this video helped me a lot sir

  • @beenakathait7325
    @beenakathait7325 5 ปีที่แล้ว

    Sir u r the best ❤🙌

  • @quynhxuantran3624
    @quynhxuantran3624 3 ปีที่แล้ว +1

    this is the best detaied mechanism explanation I could found. thank youu

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 ปีที่แล้ว

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @georgewilliams6733
    @georgewilliams6733 7 ปีที่แล้ว

    Really useful, cheers!

  • @rabiamehmood3507
    @rabiamehmood3507 5 ปีที่แล้ว +1

    Beautifully explained. Thank you!

  • @Nostalgicsforever
    @Nostalgicsforever 6 ปีที่แล้ว

    superb... thank u sir......

  • @dineshahir1291
    @dineshahir1291 3 ปีที่แล้ว +1

    Big thanks your sir❣️If i haven't seen this video I will never understand vdj recombination thanks legend of microbiology.

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 ปีที่แล้ว

      You're welcome. Glad to hear that you're getting benefit from my lectures. Please subscribe and share

  • @areejfatima4781
    @areejfatima4781 4 ปีที่แล้ว +2

    Very well explained Sir! Thank you!....Stay blessed!

  • @shuvoameer8081
    @shuvoameer8081 3 ปีที่แล้ว

    thank you sir, that was really healpful, i have difficulty to understand that TDT part , and how it cleave the unnecessary part of the gene

  • @gokularora965
    @gokularora965 2 ปีที่แล้ว +1

    The best explanation of Antibody diversity

  • @jhonyjosuecruzpelaez2227
    @jhonyjosuecruzpelaez2227 6 ปีที่แล้ว

    Great job.

  • @shrutibaurai5480
    @shrutibaurai5480 5 ปีที่แล้ว +5

    Great sir... Even in kuby it's hard to understand bt sir u made it more interesting.. Goona b very helpful in my coming exams..

  • @JamesBond-px4kg
    @JamesBond-px4kg 6 ปีที่แล้ว +3

    Sir ur videos are one of the most informative and easy to grasp on. But the only think u r lacking is your video setup, the lights ,the angle and editings. If you can improve this u ll get lots of view and subscribers from around the world.

  • @Hannah-gw9qd
    @Hannah-gw9qd 7 ปีที่แล้ว

    Thank you!

  • @mayukhroy5393
    @mayukhroy5393 4 ปีที่แล้ว +3

    This video was soo helpful, Thank you so much Sir.

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 ปีที่แล้ว

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @sarahwinkler8410
    @sarahwinkler8410 7 ปีที่แล้ว

    Thank you! Great explanation.

  • @kianagoudarzi1619
    @kianagoudarzi1619 5 ปีที่แล้ว +3

    You just saved me for my final exam mister.
    Much appreciations 🙏🏻

  • @peacefulsparrow4740
    @peacefulsparrow4740 4 ปีที่แล้ว

    First comment
    I m BS Biotechnology student of 4th semester
    Explanation is oxm
    I HV no words 💓
    Love from Pakistan

  • @skt08
    @skt08 6 ปีที่แล้ว

    U r just awesome....😀😀😀

  • @Amsebrid
    @Amsebrid 2 ปีที่แล้ว +1

    Best biology channel on TH-cam

  • @anazeba2369
    @anazeba2369 7 ปีที่แล้ว +1

    thank you sir

  • @angelon86031
    @angelon86031 5 ปีที่แล้ว +4

    Shomu thank you so much, I'm studying Biochemistry, your explanation help me so much. Best regards from Mexico City 🙏✨🔬⚗️

    • @shomusbiologyofficial
      @shomusbiologyofficial  5 ปีที่แล้ว +2

      Thank you for appreciating my efforts. Glad to hear that you are getting benefit from the videos

  • @merveoltan4015
    @merveoltan4015 5 ปีที่แล้ว +2

    You are the best. I have learned a lot from you

  • @aishwaryaudhayakumar7339
    @aishwaryaudhayakumar7339 3 ปีที่แล้ว +4

    U helped me a lot... and thank u so much sir... keep uploading ❣️

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 ปีที่แล้ว

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @labibatahsin9125
    @labibatahsin9125 3 ปีที่แล้ว +1

    Just before my exam.. It was awesome. Love from Bangladesh

  • @ParthBambhroliya
    @ParthBambhroliya 4 ปีที่แล้ว +2

    Unbelievable explanation!!

  • @belaidsalma2015
    @belaidsalma2015 3 ปีที่แล้ว +1

    It was very well explained !! Thank u so much

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 ปีที่แล้ว +1

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @matthewrandell5055
    @matthewrandell5055 7 ปีที่แล้ว +110

    Why did it get so much more difficult in the last two minutes :(

    • @sahelidas244
      @sahelidas244 7 ปีที่แล้ว +5

      exactly .. i also could not understand the VDJ part ...

    • @viveksinghchauhan7496
      @viveksinghchauhan7496 5 ปีที่แล้ว +2

      @@sahelidas244 Same here brother .

    • @catsandrandom3844
      @catsandrandom3844 5 ปีที่แล้ว +4

      Keep watching this part again and try to draw the same step by step. It's not that difficult.

    • @catsandrandom3844
      @catsandrandom3844 5 ปีที่แล้ว

      @@viveksinghchauhan7496 *Sister*

    • @huxleymarvit3832
      @huxleymarvit3832 5 ปีที่แล้ว +6

      Because he plagiarized it.

  • @minkughosh7051
    @minkughosh7051 3 ปีที่แล้ว +1

    u r the best sir👍

  • @preethisivakumar4003
    @preethisivakumar4003 5 ปีที่แล้ว +2

    Sir,really amazing ...well defined !!...

  • @Chansophornkhem
    @Chansophornkhem 5 ปีที่แล้ว +1

    so so so briliant. thanks so much

  • @mpoetsintseli3184
    @mpoetsintseli3184 ปีที่แล้ว +1

    wow it's so clear now ,thank you

  • @Sanwithz
    @Sanwithz 7 ปีที่แล้ว

    Love all you video. Thanks

  • @hafizanamal
    @hafizanamal 3 ปีที่แล้ว +1

    Thankx alot you are the solution of my all study related problems again thankx alot alot of prayers for you

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 ปีที่แล้ว +1

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @user-ep5fv1xf9u
    @user-ep5fv1xf9u 5 ปีที่แล้ว +1

    thank you ~ you are
    my teacher -from korea-

  • @macplay9765
    @macplay9765 7 ปีที่แล้ว

    its a really smart learning... watched not almost all but huge no. is there.. nd all r great.. thnk u for this tutorial .. hope u will give notes on your google + or your website..

  • @murphl
    @murphl 5 ปีที่แล้ว +1

    A Really good video.. Thanks a lot sir !

  • @user-fg9eq3wb1o
    @user-fg9eq3wb1o 3 ปีที่แล้ว +1

    I don't like immunology ..... but I try to understand it .Your explanation is nice and simple to helpe me alot ,,, Thank you

  • @haseebsheikh6551
    @haseebsheikh6551 ปีที่แล้ว +1

    You are the best
    Thank you

  • @mnrhft6692
    @mnrhft6692 ปีที่แล้ว +1

    Thank you sm!! Very clear

  • @ashmitarijal8510
    @ashmitarijal8510 3 ปีที่แล้ว +1

    This was a great help thankyou

    • @shomusbiologyofficial
      @shomusbiologyofficial  3 ปีที่แล้ว

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @ashanikarandawela8129
    @ashanikarandawela8129 10 หลายเดือนก่อน +1

    It really helped.thank you😊

  • @aquibraz5087
    @aquibraz5087 5 ปีที่แล้ว +1

    Great sir..
    Thanku so much ❤

    • @shomusbiologyofficial
      @shomusbiologyofficial  5 ปีที่แล้ว +1

      You're welcome. Glad to hear that you are getting benefit from the videos

  • @rajad1132
    @rajad1132 4 ปีที่แล้ว +1

    Simply excellent........

  • @blessingsbanda3872
    @blessingsbanda3872 3 ปีที่แล้ว +2

    Thank you Sir this was very helpful👌

  • @vineshmanohar9978
    @vineshmanohar9978 5 ปีที่แล้ว +1

    This was very useful! Thank you :)

  • @vikashmishra8744
    @vikashmishra8744 5 ปีที่แล้ว

    Shomu sir aapki..ek..baat..bahut ..achha lgta h..yhi..ki..
    That is about it...

  • @kisaakyeevelyn401
    @kisaakyeevelyn401 3 ปีที่แล้ว +1

    My best teacher ❤️❤️

  • @muskangarana8074
    @muskangarana8074 2 ปีที่แล้ว +1

    Thankyou so much sir, you made it so easy for me.

  • @drhappypill4830
    @drhappypill4830 2 ปีที่แล้ว +1

    Love youuuuu! ❤

  • @hui2077
    @hui2077 2 ปีที่แล้ว +1

    thank you so much for this video

  • @thisislekshmy123
    @thisislekshmy123 6 หลายเดือนก่อน +1

    Brilliant ❤️

  • @sayunijay4742
    @sayunijay4742 ปีที่แล้ว +1

    thankyou proff ❤

  • @zarin1897
    @zarin1897 ปีที่แล้ว +1

    Thanks a lot Brother ❤

  • @alwinaanam1231
    @alwinaanam1231 7 ปีที่แล้ว

    very helpful... thanks .

  • @raisabadhan3417
    @raisabadhan3417 6 ปีที่แล้ว

    great

  • @sajana875
    @sajana875 3 ปีที่แล้ว +1

    Great!

  • @ricasaluria8821
    @ricasaluria8821 4 ปีที่แล้ว +1

    Thank you so much. ❤️❤️❤️❤️

    • @shomusbiologyofficial
      @shomusbiologyofficial  4 ปีที่แล้ว +1

      You're welcome. Glad to hear that you're getting benefit from my lectures

  • @user-ni6id3zy3r
    @user-ni6id3zy3r 5 ปีที่แล้ว +1

    You're the best 😘

  • @benishshah9678
    @benishshah9678 6 ปีที่แล้ว +1

    ur new surcriber from Pakistan,u did great job☺
    thnxx fr making it..

  • @swapnilghosh3010
    @swapnilghosh3010 2 ปีที่แล้ว +1

    bhai korechen ki? apni tokhon 10k subscription e chhilen..... hats off

  • @amiamaira3636
    @amiamaira3636 8 หลายเดือนก่อน +1

    This legend!!!!!!

  • @parthjani2254
    @parthjani2254 5 ปีที่แล้ว +2

    Nice one Sir...

  • @pakhisingh6378
    @pakhisingh6378 2 ปีที่แล้ว +3

    Very well explained sir😊

  • @saikatsarkar5125
    @saikatsarkar5125 3 ปีที่แล้ว +1

    Great

  • @barbaradezman7855
    @barbaradezman7855 6 ปีที่แล้ว +1

    Hi, first I really like your videos but I have 2Q: 1.Why does a class switch occure later in the course of an immune response? 2.When does clonal expansion not occur?

  • @alveenasahar3381
    @alveenasahar3381 11 หลายเดือนก่อน +1

    Ur explanations are superb but I lost at 17:17 😅...but I got the main chunk of my topic ..thank u so much ..

  • @KhanjanYT
    @KhanjanYT 5 ปีที่แล้ว +1

    very helpful

  • @tatinikayal9295
    @tatinikayal9295 ปีที่แล้ว +1

    I have exam... this video helped me a lot.. thank you ☺️ sir

  • @sukhendumukhopadhyay4219
    @sukhendumukhopadhyay4219 6 ปีที่แล้ว +2

    amazing sir

  • @mohammedameen6824
    @mohammedameen6824 ปีที่แล้ว +1

    U rock bro

  • @aleehyder5798
    @aleehyder5798 3 ปีที่แล้ว

    Plz get understand somatic hyoermutation and somatic recombination( vdj )..bcz I think both process are different but mostly it is mixed in all online videos..

  • @saifurrehman7617
    @saifurrehman7617 4 ปีที่แล้ว +1

    very nice bro